Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:2.7.1.1 (
hexokinase
)
5,274
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
hexokinase
5231
ATP
1110
pyruvate kinase
728
phosphofructokinase
686
insulin
643
glucose-6-phosphate dehydrogenase
515
lactate dehydrogenase
490
glucokinase
489
ADP
384
Sep
373
Mol
361
Hexokinase
282
citrate synthase
260
glucose-6-phosphatase
251
glucose transporter
207
malate dehydrogenase
203
glycolytic enzyme
172
AMP
156
ATPase
150
phosphorylating
132
creatine kinase
130
6-phosphogluconate dehydrogenase
121
NADH
118
adenylate kinase
112
glycogen phosphorylase
107
glyceraldehyde-3-phosphate dehydrogenase
103
phosphatase
103
phosphoglucose isomerase
103
glycogen synthase
93
NADPH
92
hemoglobin
90
outer mitochondrial membrane
86
fructose-1,6-bisphosphatase
84
NAD
80
NADP
79
phosphoglycerate kinase
78
Glucokinase
77
fructokinase
76
glutamate dehydrogenase
75
enolase
73
pyruvate dehydrogenase
71
GLUT1
70
phosphoenolpyruvate carboxykinase
70
HKII
67
isocitrate dehydrogenase
66
6-phosphofructokinase
65
hexokinase II
64
porin
61
superoxide dismutase
61
aspartate aminotransferase
60
catalase
59
ATP:D-hexose 6-phosphotransferase
58
CO2
57
NAD+
56
alkaline phosphatase
56
glucosamine
55
cytochrome c
54
NMR
54
glutathione peroxidase
52
hexokinase 2
50
HKI
50
FDG
50
glutathione reductase
49
Gen
49
PHI
47
LDH
46
hexokinase 1
44
GLUT4
43
glycerol kinase
43
voltage-dependent anion channel
43
NADP+
41
glutaminase
41
cytochrome
40
endoplasmic reticulum
40
cytochrome c oxidase
39
GSH
39
alcohol dehydrogenase
39
glucagon
38
GTP
36
GLUT-4
36
more...
Disease
cancer
343
diabetes
331
tumor
310
hyperglycemia
112
hepatocellular carcinoma
108
type 2 diabetes
58
breast cancer
51
hypoglycemia
48
GSH
41
carcinoma
40
Alzheimer's disease
39
ischemia
39
obesity
35
tumor growth
35
hyperinsulinemia
35
cold
30
glioma
29
depression
26
glucose intolerance
25
SDS
25
hemolytic anemia
23
tumor progression
19
leukemia
18
MCF
18
neuroblastoma
17
carcinogenesis
17
insulinoma
16
adenocarcinoma
16
tumorigenesis
16
Schistosoma mansoni
16
anemia
16
melanoma
15
idiopathic thrombocytopenic purpura
15
hypertension
15
SEM
14
colon cancer
14
hyperthyroidism
13
worms
13
type 1 diabetes
12
metastases
12
hypothyroidism
12
dyslipidemia
12
dehydration
12
mole
11
mole
11
cataract
11
hyperlipidemia
11
colorectal cancer
10
lung cancer
10
gastric cancer
10
sarcoma
10
Chagas
9
fatty liver
9
squamous cell carcinoma
9
epididymis
9
liver cancer
9
cystic fibrosis
9
chronic obstructive pulmonary disease
8
sepsis
8
cirrhosis
8
sepsis
8
uterus
8
dementia
8
liver cancer
8
heart failure
8
FAS
7
B-cell lymphoma
7
malaria
7
amebiasis
7
malnutrition
7
lymphoma
7
Parry
7
metabolic disorder
6
Blocking
6
ovarian cancer
6
rheumatoid arthritis
6
DBA
6
Parkinson's disease
6
non-small cell lung cancer
6
fits
6
more...
Symptom
starvation
70
fatigue
17
anesthesia
17
exhaustion
15
seizures
9
collapse
6
acidity
5
polydipsia
4
hypothermia
4
tremor
4
weakness
4
hyperoxia
4
polyuria
4
anorexia
3
agitation
3
acute stress
3
overweight
3
Anoxia
3
pain
3
dyspnea
2
hypercapnia
2
functional recovery
2
vomiting
2
cachexia
2
insomnia
1
respiratory distress
1
nausea
1
testicular pain
1
numbness
1
hepatomegaly
1
hunger
1
Decreased activity
1
twitching
1
ataxia
1
regurgitation
1
thinning
1
POA
1
erythema
1
Ill
1
asterixis
1
lethargy
1
flushing
1
splenomegaly
1
stigma
1
syncope
1
hypocapnia
1
headache
1
discomfort
1
decreased appetite
1
myalgia
1
discomfort
1
Drug
NADH
123
citric acid
41
Fructose
28
Leaf
25
ascorbate
19
ROS
19
lactose
18
lysine
14
vitamin E
14
Cibacron Blue
10
FAD
8
Adenosine triphosphate
8
Glucagon
7
Gel
7
Cardiovasc
7
Portal
6
NH3
6
Bayer
6
Metrizamide
6
NAG
5
DNase I
5
CaCl2
5
Galactose
5
CSF
5
CaCl2
5
pyridoxal phosphate
5
CaCl2
5
Adriamycin
5
caffeine
4
Nephron
4
Lactose
4
Glutathione
4
CDP
4
Asn
4
Cellulose acetate
3
Nephron
3
MAP
3
Dermatol
3
Biopolymers
3
Alanine
3
Ethanol
3
Vitamin A
3
Rosiglitazone
3
Glycerol
3
Captopril
2
Adenosine deaminase
2
Check
2
Amiloride
2
MgSO4
2
MRC
2
Salicylate
2
PTH
2
Gleevec
2
IL-2
2
Glide
2
Amiloride
2
Naftidrofuryl
2
ABC
2
ALA
2
Serum albumin
2
SMP
2
Vitamin B
2
Bifidobacterium
2
Wine
2
Clofibrate
2
Iotrolan
2
Diurnal
2
K-252a
2
Carboxyatractyloside
2
Bupivacaine
1
Pyridoxal phosphate
1
PCB
1
Xylocaine
1
Adenyl
1
Bevacizumab
1
TES
1
Mutagen
1
Thiopentone
1
Luteinizing
1
Itraconazole
1
more...
Enzyme
hexokinase
5274
phosphofructokinase
757
pyruvate kinase
729
glucose-6-phosphate dehydrogenase
612
lactate dehydrogenase
522
glucokinase
493
citrate synthase
266
glucose-6-phosphatase
255
malate dehydrogenase
217
phosphorylase
208
phosphoglucose isomerase
207
aldolase
201
ATPase
180
phosphoglucomutase
158
creatine kinase
152
glyceraldehyde-3-phosphate dehydrogenase
152
glyceraldehyde-3-phosphate dehydrogenase
131
6-phosphogluconate dehydrogenase
124
6-phosphogluconate dehydrogenase
124
succinate dehydrogenase
116
glyceraldehyde-3-phosphate dehydrogenase
116
adenylate kinase
115
glyceraldehyde-3-phosphate dehydrogenase
110
phosphoglycerate kinase
103
glyceraldehyde-3-phosphate dehydrogenase
103
invertase
95
phosphoenolpyruvate carboxykinase
87
pyruvate dehydrogenase
87
phosphoenolpyruvate carboxykinase
83
phosphoenolpyruvate carboxykinase
83
protein kinase
80
glutamate dehydrogenase
79
glutamate dehydrogenase
79
glutamate dehydrogenase
79
glucose oxidase
77
enolase
75
aspartate aminotransferase
75
isocitrate dehydrogenase
73
isocitrate dehydrogenase
73
pyruvate dehydrogenase
72
pyruvate dehydrogenase
71
superoxide dismutase
69
fructokinase
68
glycerol-3-phosphate dehydrogenase
66
catalase
64
glycerol-3-phosphate dehydrogenase
64
alkaline phosphatase
56
cytochrome oxidase
54
glycerol kinase
53
glutathione peroxidase
53
alanine aminotransferase
52
fructose 1,6-bisphosphatase
52
glutathione reductase
50
alcohol dehydrogenase
44
AMP-activated protein kinase
43
glutaminase
43
3-hydroxyacyl-CoA dehydrogenase
43
alpha-ketoglutarate dehydrogenase
42
peroxidase
40
sucrose synthase
40
PGM
40
diaphorase
40
3-hydroxyacyl-CoA dehydrogenase
36
alpha-glucosidase
36
acetylcholinesterase
33
HK2
33
histidine kinase
33
glucose dehydrogenase
32
acid phosphatase
32
trypsin
31
CPR
29
phosphomannose isomerase
28
ATP synthase
28
pyruvate carboxylase
27
aldose reductase
26
apyrase
26
mitogen-activated protein kinase
25
calcineurin
25
sorbitol dehydrogenase
24
succinic dehydrogenase
23
more...
Compound
glucose
3092
ATP
1111
phosphate
953
galactose
421
ADP
409
ADP
384
ADP
384
Dec
376
oxygen
308
hexose
282
glucose-6-phosphate
276
hexose
249
hexose
249
hexose
249
Clin
203
pentose
183
pentose
179
pentose
179
pentose
179
water
169
AMP
166
DNA
147
sodium
145
calcium
144
NAD
136
NADP
122
NADH
122
glutamate
106
glycerol
104
CoA
98
acetate
98
NADPH
94
NADPH
92
Mg2+
86
NAD
80
glutamine
77
ethanol
75
CO2
72
alanine
72
Insulin
72
nitrogen
64
hydrogen
62
alloxan
58
sulfate
57
Lactate
55
UTP
48
urea
47
DEAE
47
2-oxoglutarate
46
salt
45
GSH
44
GSH
44
ammonium
43
Sucrose
43
cAMP
43
GlcNAc
42
nicotinamide
42
cysteine
41
Glycogen
41
potassium
41
alcohol dehydrogenase
40
ammonia
40
2,3-diphosphoglycerate
40
Glucose 6-phosphate
39
xylose
37
TCA
36
GTP
36
phosphocreatine
34
adenylate
33
tyrosine
32
acetyl-CoA
32
cyanide
31
UDP
30
leucine
30
SDS
30
Fructose
29
serine
29
UDP-glucose
28
arginine
26
lysine
25
more...