Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:2.7.1.1 (
hexokinase
)
5,274
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
hexokinase
5231
ATP
1110
pyruvate kinase
728
phosphofructokinase
686
insulin
643
glucose-6-phosphate dehydrogenase
515
lactate dehydrogenase
490
glucokinase
489
ADP
384
Sep
373
Mol
361
Hexokinase
282
citrate synthase
260
glucose-6-phosphatase
251
glucose transporter
207
malate dehydrogenase
203
glycolytic enzyme
172
AMP
156
ATPase
150
phosphorylating
132
creatine kinase
130
6-phosphogluconate dehydrogenase
121
NADH
118
adenylate kinase
112
glycogen phosphorylase
107
phosphoglucose isomerase
103
glyceraldehyde-3-phosphate dehydrogenase
103
phosphatase
103
glycogen synthase
93
NADPH
92
hemoglobin
90
outer mitochondrial membrane
86
fructose-1,6-bisphosphatase
84
NAD
80
NADP
79
phosphoglycerate kinase
78
Glucokinase
77
fructokinase
76
glutamate dehydrogenase
75
enolase
73
more...
Disease
cancer
343
diabetes
331
tumor
310
hyperglycemia
112
hepatocellular carcinoma
108
type 2 diabetes
58
breast cancer
51
hypoglycemia
48
GSH
41
carcinoma
40
ischemia
39
Alzheimer's disease
39
obesity
35
hyperinsulinemia
35
tumor growth
35
cold
30
glioma
29
depression
26
glucose intolerance
25
SDS
25
hemolytic anemia
23
tumor progression
19
leukemia
18
MCF
18
neuroblastoma
17
carcinogenesis
17
Schistosoma mansoni
16
insulinoma
16
tumorigenesis
16
adenocarcinoma
16
anemia
16
hypertension
15
idiopathic thrombocytopenic purpura
15
melanoma
15
SEM
14
colon cancer
14
hyperthyroidism
13
worms
13
metastases
12
hypothyroidism
12
more...
Symptom
starvation
70
anesthesia
17
fatigue
17
exhaustion
15
seizures
9
collapse
6
acidity
5
hyperoxia
4
polydipsia
4
polyuria
4
hypothermia
4
weakness
4
tremor
4
anorexia
3
agitation
3
acute stress
3
Anoxia
3
overweight
3
pain
3
hypercapnia
2
cachexia
2
vomiting
2
functional recovery
2
dyspnea
2
insomnia
1
respiratory distress
1
nausea
1
testicular pain
1
numbness
1
hepatomegaly
1
hunger
1
Decreased activity
1
twitching
1
ataxia
1
thinning
1
POA
1
erythema
1
splenomegaly
1
lethargy
1
stigma
1
more...
Drug
NADH
123
citric acid
41
Fructose
28
Leaf
25
ROS
19
ascorbate
19
lactose
18
vitamin E
14
lysine
14
Cibacron Blue
10
FAD
8
Adenosine triphosphate
8
Cardiovasc
7
Glucagon
7
Gel
7
NH3
6
Metrizamide
6
Portal
6
Bayer
6
NAG
5
CaCl2
5
Adriamycin
5
DNase I
5
CaCl2
5
Galactose
5
CSF
5
CaCl2
5
pyridoxal phosphate
5
CDP
4
caffeine
4
Glutathione
4
Asn
4
Lactose
4
Nephron
4
Dermatol
3
Cellulose acetate
3
Biopolymers
3
Ethanol
3
Vitamin A
3
MAP
3
more...
Enzyme
hexokinase
5274
phosphofructokinase
757
pyruvate kinase
729
glucose-6-phosphate dehydrogenase
612
lactate dehydrogenase
522
glucokinase
493
citrate synthase
266
glucose-6-phosphatase
255
malate dehydrogenase
217
phosphorylase
208
phosphoglucose isomerase
207
aldolase
201
ATPase
180
phosphoglucomutase
158
creatine kinase
152
glyceraldehyde-3-phosphate dehydrogenase
152
glyceraldehyde-3-phosphate dehydrogenase
131
6-phosphogluconate dehydrogenase
124
6-phosphogluconate dehydrogenase
124
glyceraldehyde-3-phosphate dehydrogenase
116
succinate dehydrogenase
116
adenylate kinase
115
glyceraldehyde-3-phosphate dehydrogenase
110
phosphoglycerate kinase
103
glyceraldehyde-3-phosphate dehydrogenase
103
invertase
95
pyruvate dehydrogenase
87
phosphoenolpyruvate carboxykinase
87
phosphoenolpyruvate carboxykinase
83
phosphoenolpyruvate carboxykinase
83
protein kinase
80
glutamate dehydrogenase
79
glutamate dehydrogenase
79
glutamate dehydrogenase
79
glucose oxidase
77
enolase
75
aspartate aminotransferase
75
isocitrate dehydrogenase
73
isocitrate dehydrogenase
73
pyruvate dehydrogenase
72
more...
Compound
glucose
3092
ATP
1111
phosphate
953
galactose
421
ADP
409
ADP
384
ADP
384
Dec
376
oxygen
308
hexose
282
glucose-6-phosphate
276
hexose
249
hexose
249
hexose
249
Clin
203
pentose
183
pentose
179
pentose
179
pentose
179
water
169
AMP
166
DNA
147
sodium
145
calcium
144
NAD
136
NADH
122
NADP
122
glutamate
106
glycerol
104
acetate
98
CoA
98
NADPH
94
NADPH
92
Mg2+
86
NAD
80
glutamine
77
ethanol
75
alanine
72
CO2
72
Insulin
72
more...