Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:2.7.1.1 (hexokinase)
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Human Gene/Protein
ATP:D-hexose 6-phosphotransferase 12.6
EIF-2B 12.6
HKDC1 protein 12.6
GPR107 protein 12.6
hexokinase 12.6
Hexokinase type I 12.4
hexokinase III 12.2
Hexokinase-2 12.2
Hexokinase 11.6
G6d 11.6
GLUT-9 11.6
NADH dehydrogenase (ubiquinone) Fe-S protein 2 11.6
arrestin domain containing 4 11.6
hexokinase 4 11.6
hHK1 11.6
Kelch-like protein 7 11.6
solute carrier family 2 (facilitated glucose transporter), member 3 11.6
Hexokinase III 11.6
kelch-like 12 11.6
hexokinase 3 11.5
more...
Disease
Hexokinase deficiency 12.6
Chronic hemolytic anemia 10.2
HPLE 10.0
CLL variants 10.0
GST6 8.8
sideroblastosis 8.7
fructosuria 8.6
trisomy 10p 8.4
metastatic papillary thyroid cancer 8.0
Type V hyperlipoproteinemia 7.9
Pyridoxine deficiency 7.8
Biotin deficiency 7.6
pyruvate kinase deficiency 7.5
Disuse atrophy 7.4
pediatric liver cancer 7.2
Glycerol kinase deficiency 7.1
MODY2 7.1
Erythroleukemia 6.9
preneoplastic state 6.9
Hers 6.9
more...
Symptom
Anoxia 5.0
asterixis 4.9
testicular pain 4.1
starvation 4.1
POA 3.5
Decreased activity 3.5
polydipsia 3.5
polyuria 3.0
exhaustion 2.7
decreased appetite 2.4
hyperoxia 2.2
acute stress 2.0
hypocapnia 1.8
twitching 1.6
cachexia 1.1
acidity 1.0
fatigue 1.0
hypercapnia 0.6
agitation 0.6
hypothermia 0.5
more...
Drug
Fructose-1,6-Diphosphate 12.6
Fructose-6-Phosphate 11.0
Sodium Pentobarbital 11.0
1,4-Dithiothreitol 9.1
Carboxyatractyloside 8.7
Iotrolan 8.1
Adenyl 7.9
Berberine chloride 7.8
Insulin glulisine 7.5
Lonafarnib 7.4
Naftidrofuryl 7.3
Cibacron Blue 7.0
Penfluridol 6.9
1-Deoxynojirimycin 6.9
Fructose 6.5
Ciglitazone 6.3
Cellulose acetate 6.1
Metrizamide 5.9
Glybenclamide 5.9
Marcaine 5.8
more...
Enzyme
hexokinase 12.6
mannitol-1-phosphatase 10.9
aldose-6-phosphate reductase 10.3
glucose-1-phosphate cytidylyltransferase 10.2
EC 2.3.1.14 10.2
phosphofructokinase 10.2
fructokinase 10.1
N-acetylglucosamine kinase 10.1
HK3 10.1
glucokinase 10.0
mannokinase 9.9
pyruvate kinase 9.7
oxoglutarate dehydrogenase 9.6
L-arabinitol dehydrogenase 9.6
phosphoglucose isomerase 9.5
2,3-bisphosphoglycerate phosphatase 9.5
phosphoglyceromutase 9.5
polyphosphate glucokinase 9.5
phosphoglucomutase 9.5
ADP-dependent glucokinase 9.4
more...
Compound
N-Acetylneuraminic acid 9-phosphate 12.6
3-Chloromethylthiochromone-1,1-dioxide 11.6
Agaricic acid 11.6
C6H12S 11.6
Triethyloxonium tetrafluoroborate 11.0
Pentoxyl 10.6
Echitamine 10.0
2,5-Anhydro-D-mannitol 10.0
6-Deoxy-D-glucose 9.6
Pelentan 9.6
Hymenoxon 9.4
Glucose 6-phosphate 9.3
L-Ribulose 5-phosphate 9.2
hept-2-ulose 9.1
Isopulegol 9.0
F6P 8.9
F6P 8.9
C6H12O6 8.9
glucose-6-phosphate 8.9
Isopulegol 8.9
more...