Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:2.7.1.1 (
hexokinase
)
5,274
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
The kinetic properties of
hexokinase
of L1210 ascites tumor cells propagated in DBA/2HaD mice are altered by treatment of the mice with the modified nucleoside N6-(delta2-isopentenyl)-adensone (
IPA
). Relative to animals not treated with
IPA
, ascites cell
hexokinase
showed an increased affinity for ATP and a decreased affinity for glucose as a result of
IPA
treatment. The heat stability of the enzyme was different in treated and untreated mice. It was concluded that
IPA
treatment may either produce changes in enzyme conformation which resulted in a change in control mechanisms or may induce the formation of a
hexokinase
isoenzyme.
...
PMID:Effect of N6-(delta2-isopentenyl)adenosine treatment in vivo on hexokinase activity of mouse L 1210 cells. 105 42
