Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:2.7.1.1 (
hexokinase
)
5,274
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Partial sympathectomy of rat liver, carried out by bilateral section of
celiac
nerves, caused a distinct increase in the activity of
hexokinase
and glucose-6-phosphate dehydrogenase and (less distinctly) of 6-phosphogluconate dehydrogenase and lactate dehydrogenase in liver tissue. The alterations in glucokinase activity were not statistically significant. Noradrenaline disappeared completely from rat liver after the
celiac
nerves section. Activities of the above-mentioned enzymes were altered to the same degree in sympathectomized liver of adrenalectomized animals. The increase in the
hexokinase
and glucose-6-phosphate dehydrogenase activity was prevented by administration of actinomycin D immediately after the section of
celiac
nerves. The data obtained suggest that after section of liver
celiac
nerves the alterations in the enzymatic activities are determined by the increase of their biosynthesis and occur as a result of impairment of liver sympathetic innervation.
...
PMID:[Nature of changes in the activity of certain enzymes of energy metabolism in the liver after partial sympathectomy]. 102 52
