Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:2.6.1.44 (
AGT
)
770
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
The sensitivity of the low ionic strength solution antiglobulin test (LISS-AGT), polyethylene glycol antiglobulin test (PEG-AGT), low ionic strength solution solid-phase antiglobulin test (LISS-SPAT), gel low ionic strength solution antiglobulin test (GEL-LISS), and gel papain test (GEL-PAP) was compared in titration studies of 460 sera containing identified IgG alloantibodies. The GEL-
PAP
was 100% sensitive to detect Rh antibodies, whereas the PEG-
AGT
was the most sensitive to detect Kell, Duffy, Kidd, Ss, and rare blood group antibodies. The better performance of PEG-
AGT
was especially obvious with Kell, Duffy, and Ss antibodies (S = 100%). When the sensitivity of the LISS-
AGT
, PEG-
AGT
, GEL-LISS, and GEL-
PAP
was evaluated in different routines, the GEL-LISS showed to be more sensitive than PEG-
AGT
in the detection of clinically significant antibodies. These discrepant results showed that the performance of a technique may change when it is applied as a routine.
...
PMID:Evaluation of recent techniques for detection of red blood cell antibodies in sera of reference samples, patients, pregnant women, and blood donors. 888 3
