Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:2.6.1.2 (
alanine aminotransferase
)
26,722
document(s) hit in 31,850,051 MEDLINE articles (0.02 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
alanine aminotransferase
13720
aspartate aminotransferase
8708
AST
4535
alkaline phosphatase
3644
GPT
2403
lactate dehydrogenase
1854
superoxide dismutase
1778
GSH
1757
albumin
1746
Sep
1700
catalase
1400
interferon
1191
TNF
1155
glutathione peroxidase
1028
ALP
1007
LDH
989
insulin
986
tumor necrosis factor
970
hemoglobin
823
Mol
763
IL-6
715
creatine kinase
694
cytokine
637
lipopolysaccharide
616
SOD
611
caspase-3
572
HDL
558
IFN
539
GGT
526
collagen
515
glutamate pyruvate transaminase
502
surface antigen
489
prothrombin
443
galactosamine
408
gamma-glutamyltransferase
363
inducible nitric oxide synthase
362
serum albumin
358
myeloperoxidase
350
C-reactive protein
348
interleukin-6
336
CAT
323
glutamate dehydrogenase
316
IL-10
308
amylase
302
glutathione reductase
294
gamma-glutamyl transpeptidase
284
Bcl-2
264
microsomal
257
LPS
256
glutathione S-transferase
249
cytochrome P450
247
CD4
245
ATP
234
ferritin
231
TNF-alpha
218
GTG
214
interferon-alpha
214
heme oxygenase-1
201
TLR4
198
sorbitol dehydrogenase
195
acid phosphatase
192
Nrf2
190
gut
188
tumor necrosis factor alpha
187
endoplasmic reticulum
186
lipase
186
antioxidant enzyme
185
CYP2E1
181
She
171
SMA
171
fibrinogen
165
Aspartate aminotransferase
164
GST
163
adiponectin
161
CD8
154
ROS
154
p65
148
p53
147
serum protein
145
cytochrome P-450
145
CPK
143
erythroid
140
smooth muscle actin
139
leptin
137
CRP
137
proliferating cell nuclear antigen
132
JNK
131
HO-1
126
acetylcholinesterase
124
peroxisome proliferator-activated receptor
118
alpha-fetoprotein
116
p38
115
interferon alpha
115
COX-2
114
transferrin
113
thromboplastin
111
thymus
110
MAPK
108
IL-4
107
PPAR
106
IL-2
105
cyclooxygenase-2
105
cytochrome
103
nitric oxide synthase
103
glucose-6-phosphate dehydrogenase
103
lysozyme
102
ATPase
101
carp
101
Pol
100
Fas
100
gamma-glutamyltranspeptidase
99
cytochrome P450 2E1
98
glutamine synthetase
96
IFN-gamma
94
fatty acid synthase
91
alcohol dehydrogenase
91
phosphatase
91
NAD
89
malate dehydrogenase
88
caspase-9
88
HSP70
87
cytochrome c
87
pyruvate kinase
87
chemokine
86
peroxidase
85
IL-1
85
Alanine aminotransferase
84
glycoprotein
83
Alkaline phosphatase
83
kit
83
IgA
82
AMPK
82
NMR
82
reductase
81
metallothionein
81
P450
81
IL-8
80
lymphoid
80
Cytokine
79
MCP-1
78
isocitrate dehydrogenase
77
GTP
76
NADPH
76
HCC
75
glucose-6-phosphatase
75
RIN
74
ERK
74
AFP
74
mTOR
73
A-I
73
FIB
73
phosphoenolpyruvate carboxykinase
71
vascular endothelial growth factor
70
PI3K
70
PEG
70
NADH
69
xenobiotic
69
alpha-smooth muscle actin
69
epididymal
69
interleukin 6
69
more...
Disease
chronic hepatitis
2284
hepatitis
1869
hepatitis B
1775
GSH
1757
hepatitis C
1686
cirrhosis
1477
liver disease
1445
fatty liver
1030
hepatocellular carcinoma
1004
cancer
977
diabetes
809
ischemia
790
tumor
772
liver fibrosis
736
obesity
667
viremia
427
cholestasis
426
acute hepatitis
418
HIV
410
viral hepatitis
391
chronic liver disease
381
sepsis
354
sepsis
326
metabolic syndrome
315
thrombocytopenia
309
alcoholic fatty liver
308
anemia
307
hypertension
302
virus infection
290
type 2 diabetes
283
chronic active hepatitis
270
Nonalcoholic fatty liver
261
cold
247
pneumonia
235
hyperlipidemia
234
rash
210
liver cancer
207
immunodeficiency
207
depression
204
hyperglycemia
193
infectious diseases
190
hepatitis A
184
Hepatotoxicity
173
neutropenia
157
carcinoma
154
dyslipidemia
154
eosinophilia
154
cardiovascular disease
148
hypercholesterolemia
139
leukopenia
131
pruritus
129
lymphoma
129
atherosclerosis
128
liver cancer
122
breast cancer
120
carcinogenesis
119
primary biliary cirrhosis
117
myocardial infarction
114
hyperbilirubinemia
114
hepatitis E
113
tuberculosis
112
alcoholism
110
AIDS
108
urinary tract infection
107
iron overload
106
renal disease
106
proteinuria
105
bronchitis
103
alcohol abuse
102
cytomegalovirus
102
hypoglycemia
95
tumor growth
95
chronic persistent hepatitis
94
renal failure
91
Chronic hepatitis B
88
stroke
87
portal hypertension
85
malnutrition
84
cholangitis
83
leukemia
81
hepatic encephalopathy
81
gallstones
79
tonsillitis
79
hepatitis G
78
dengue
77
HCC
75
acute pancreatitis
74
rheumatoid arthritis
73
Infection
72
metastases
71
glucose intolerance
71
malaria
70
arthritis
69
pancreatitis
68
alcoholic hepatitis
67
influenza
65
encephalopathy
65
thalassemia
65
West
64
Haemophilus
63
lymphadenopathy
63
Epstein
60
ACP
60
myopathy
59
B-cell lymphoma
59
acute renal failure
59
bronchitis
58
Acute liver failure
58
Klebsiella
57
meningitis
57
Chronic hepatitis C
57
lymphadenitis
57
heart failure
56
coagulopathy
56
disseminated intravascular coagulation
55
adenocarcinoma
54
lung cancer
54
Hepatocellular carcinoma
54
hyperinsulinemia
53
hepatitis D
53
posttransfusion hepatitis
53
obstructive jaundice
53
schistosomiasis
53
dehydration
53
hypothyroidism
52
biliary obstruction
50
coma
50
Cirrhosis
49
haemophilia
48
SEM
48
peritonitis
47
EIA
47
acute myeloid leukemia
47
fits
46
systemic lupus erythematosus
46
bronchopneumonia
45
melanoma
45
NAME
45
lymphopenia
44
Wilson's disease
44
uterus
44
hyperthyroidism
44
graft-versus-host disease
43
LAP
43
sickle cell disease
42
tumorigenesis
42
plaque
42
NS3
41
Alcoholic liver disease
41
thrombocytosis
41
acute myocardial infarction
41
primary sclerosing cholangitis
40
MIP
40
pyelonephritis
40
epilepsy
39
enteritis
38
hemorrhagic fever
38
FAS
37
prostate cancer
37
colitis
37
more...
Symptom
diarrhea
433
fatigue
280
vomiting
263
nausea
233
hepatomegaly
222
anorexia
200
anesthesia
196
pain
190
abdominal pain
161
overweight
148
headache
118
weakness
98
splenomegaly
90
myalgia
83
lethargy
76
cough
71
nausea and vomiting
71
Ill
62
arthralgia
55
starvation
54
dyspnea
54
seizures
53
hypothermia
46
erythema
45
hepatosplenomegaly
42
chills
33
constipation
31
collapse
30
exhaustion
29
epigastric pain
29
hypoproteinemia
28
respiratory distress
28
discomfort
23
dizziness
23
asthenia
23
tremor
23
polyuria
22
oliguria
22
discomfort
22
decreased appetite
21
analgesia
21
polydipsia
19
ataxia
18
sleepiness
17
sore throat
17
insomnia
17
right upper quadrant pain
16
chest pain
15
agitation
15
emaciation
14
angina
13
acidity
13
fever of unknown origin
13
functional recovery
12
numbness
12
flushing
12
abdominal discomfort
11
dark urine
11
cachexia
11
tachypnea
10
pallor
9
back pain
9
shortness of breath
9
hypotonia
9
skin irritation
8
thinning
8
paresthesia
8
hyperoxia
8
apathy
8
syncope
7
nasal discharge
7
colic
7
vertigo
6
acute abdominal pain
6
regurgitation
6
paresis
6
hot flushes
6
No adverse effect
5
incoordination
5
dysuria
5
consciousness disturbance
5
night sweats
5
acute stress
5
spasm
5
tingling
5
urinary frequency
5
jaundice of the skin
5
hemoptysis
4
rigors
4
cyanosis
4
rhinorrhea
4
hunger
4
hyperemesis gravidarum
4
hypocapnia
4
bone pain
4
intestinal bleeding
4
low back pain
4
stomach pain
4
muscle cramps
4
HSA
4
muscle rigidity
4
nasal congestion
4
Welt
4
acute abdomen
4
abdominal cramps
4
memory loss
4
Flare
3
asterixis
3
retching
3
tinnitus
3
hypercapnia
3
wheezing
3
tonic-clonic seizure
3
leg pain
3
menopausal symptoms
3
leg edema
3
dysarthria
3
Gastrointestinal symptoms
3
excessive sweating
3
muscle stiffness
3
spasticity
3
myoclonus
3
abdominal fullness
3
lassitude
3
flank pain
3
Wind
3
hangover
3
adenitis
3
ataxic gait
3
despair
3
bloating
3
ketonuria
3
prostration
3
Decreased activity
3
exertional dyspnea
3
stridor
2
livedo
2
hot flashes
2
body pain
2
dry skin
2
Flu-like symptoms
2
cerebellar ataxia
2
cancer pain
2
non-productive cough
2
anal pain
2
Murphy's sign
2
drooling
2
periorbital edema
2
labored breathing
2
neck pain
2
staggering gait
2
impaired motor coordination
2
dystonia
2
CSR
2
mental fatigue
2
neuralgia
2
ophthalmoplegia
2
stigma
2
clubbing
2
knee pain
2
more...
Drug
vitamin E
262
ascorbate
204
ROS
154
Ethanol
115
IL-2
105
IFN-gamma
93
lysine
74
NADH
65
Monit
65
Albumin
62
ROC
62
Glutathione
56
CSF
54
Alanine
54
pyridoxal phosphate
53
caffeine
49
EE2
48
Cardiovasc
46
Vitamin E
43
Dermatol
41
ENT
41
Serum albumin
41
ALA
39
Portal
38
CTX
34
Bifidobacterium
31
ampicillin
31
Nephron
29
Nephron
29
MAP
28
PMEA
27
Entecavir
26
Entecavir
26
CCL
25
SBT
24
Vitamin B
22
Dial
22
Heme
21
ZnO
21
Ringer's solution
21
Fructose
21
AZT
21
Simvastatin
21
NH3
21
Leaf
21
Biopolymers
21
NAG
21
TAC
20
citric acid
20
Rosiglitazone
19
lactose
19
Isoniazid
18
Fraction
18
Glycyrrhiza
18
Ginseng
17
niacin
16
CTX
16
Adefovir dipivoxil
16
CTX
16
PMPA
15
IFN-beta
15
IPM
15
PTH
15
Telbivudine
15
G-CSF
14
Vitamin A
14
TAK
14
CPZ
14
Aloe
13
AZT
13
Tacrolimus
13
Acacia
13
CDZM
12
Prednisolone
12
Tenofovir
12
Rutin
12
Troglitazone
12
Adriamycin
11
Rosuvastatin
11
OTC
11
Retinoic acid
10
Mutagen
10
Prednisone
10
Gel
10
Nitric Oxide
10
CEZ
9
PCB
9
Lipiodol
9
FAD
9
Ceftazidime
9
CMZ
9
Azithromycin
9
PAPM/BP
9
Norplant
9
CZOP
9
Sorafenib
9
Ximelagatran
9
Ganciclovir
9
TiO2
8
CPR
8
ZnCl2
8
Emodin
8
Emodin
8
Isotretinoin
8
ZnCl2
8
Lovastatin
8
Indomethacin
8
ETA
8
Liraglutide
7
Docetaxel
7
Infliximab
7
Bosentan
7
Lead acetate
7
ABC
7
Ketoconazole
7
DMI
7
EPA
7
ADR
7
Bosentan
7
Aminoguanidine
7
CTM
7
Fluorescein
7
DM1
7
AMC
7
Infliximab
7
Furan
7
Ezetimibe
7
Histamine
7
Swertia
6
CZON
6
TAT
6
Olive oil
6
Kenyan
6
Rituximab
6
Itraconazole
6
Cefprozil
6
ACT
6
Capsicum
6
MRC
6
Indocyanine green
6
LMOX
6
ADM
6
ICI
6
HCH
6
Clofibrate
6
Ranitidine
6
BLM
6
MEPM
6
p75
6
Pegasys
6
Fluconazole
6
DPA
6
Caspofungin
6
Intron A
5
RFP
5
FMOX
5
Glucagon
5
Doxycycline
5
NVP
5
Honey
5
more...
Enzyme
alanine aminotransferase
26722
aspartate aminotransferase
13093
AST
4535
alkaline phosphatase
3647
superoxide dismutase
2325
lactate dehydrogenase
2024
catalase
1690
gamma-glutamyl transpeptidase
1643
glutathione peroxidase
1045
creatine kinase
924
peroxidase
438
caspase-3
433
glutathione S-transferase
414
mitogen-activated protein kinase
339
glutamate dehydrogenase
328
glutamate dehydrogenase
328
glutamate dehydrogenase
327
acetylcholinesterase
315
glutathione reductase
295
cholinesterase
250
sorbitol dehydrogenase
195
lipase
194
acid phosphatase
192
ERK
174
AMP-activated protein kinase
141
glucose-6-phosphate dehydrogenase
128
malate dehydrogenase
125
protein kinase
122
ATPase
120
thromboplastin
116
lysozyme
103
alcohol dehydrogenase
101
glutamine synthetase
97
reverse transcriptase
97
aldolase
91
isocitrate dehydrogenase
90
aldehyde dehydrogenase
89
pyruvate kinase
88
focal adhesion kinase
86
phosphoenolpyruvate carboxykinase
83
AMPK
82
AMPK
82
phosphoenolpyruvate carboxykinase
81
phosphoenolpyruvate carboxykinase
80
isocitrate dehydrogenase
78
glucose-6-phosphatase
76
ceruloplasmin
71
demethylase
68
collagenase
67
arginase
67
caspase-9
66
succinate dehydrogenase
64
heme oxygenase
64
NQO1
63
thrombin
61
xanthine oxidase
61
transpeptidase
58
NO synthase
55
acetyl-CoA carboxylase
53
DNA polymerase
53
hexokinase
52
CYP3A4
48
luciferase
48
CPT
48
PARP
48
ACE
47
leucine aminopeptidase
46
aldehyde dehydrogenase
44
caspase-1
44
5'-nucleotidase
42
citrate synthase
42
CPR
41
lipoprotein lipase
40
alpha-amylase
40
aldehyde dehydrogenase
40
MIP
40
aldehyde dehydrogenase
40
aldehyde dehydrogenase
40
ornithine transcarbamylase
39
trypsin
38
tyrosine aminotransferase
38
glucokinase
37
phosphorylase
36
UDP-glucuronosyltransferase
35
gamma-glutamylcysteine synthetase
35
caspase-8
34
pyruvate dehydrogenase
34
delta-aminolevulinic acid dehydratase
34
adenosine deaminase
33
RNA polymerase
32
glutaminase
31
NOS
31
phosphofructokinase
31
beta-glucuronidase
30
GLO
30
MDH
30
MDH
30
GSK
29
protein kinase C
28
beta-lactamase
28
ornithine decarboxylase
27
6-phosphogluconate dehydrogenase
27
6-phosphogluconate dehydrogenase
27
CYP7A1
26
lactic acid dehydrogenase
26
pyruvate carboxylase
26
type III procollagen
26
NADPH oxidase
25
complex I
25
adenosine deaminase
25
NADPH oxidase
24
CPT
24
fructose 1,6-bisphosphatase
24
CPT
24
transcriptase
22
glyceraldehyde-3-phosphate dehydrogenase
22
phosphoglucomutase
22
GABA transaminase
22
pyruvate dehydrogenase
22
pyruvate dehydrogenase
22
phosphoglucose isomerase
21
thymidine kinase
21
ACS
21
ECH
20
diaphorase
20
cytochrome oxidase
20
phospholipase A2
20
renin
20
paraoxonase
20
glutamate decarboxylase
19
elastase
19
glyceraldehyde-3-phosphate dehydrogenase
19
diamine oxidase
18
APC
18
phosphodiesterase
18
MAP
18
guanase
18
alpha-ketoglutarate dehydrogenase
18
paraoxonase
18
purine nucleoside phosphorylase
18
adenylate kinase
17
lactic acid dehydrogenase
17
PGM
17
phosphatidylinositol 3-kinase
17
glutamate synthase
17
lactic acid dehydrogenase
17
carboxylesterase
17
proteasome
17
MEK
16
glutamate synthase
16
glyceraldehyde-3-phosphate dehydrogenase
16
glutamate synthase
16
MMP
16
neutrophil elastase
16
LPL
16
nucleotidase
15
phosphoinositide 3-kinase
15
monoamine oxidase
15
nitrate reductase
15
3-hydroxy-3-methylglutaryl coenzyme A reductase
14
more...
Compound
glucose
2576
creatinine
2473
GPT
2403
DNA
2197
urea
2147
Dec
1856
GSH
1803
GSH
1803
Clin
1625
water
1279
TNF
1155
nitrogen
1054
ALP
1007
oxygen
983
ethanol
909
sodium
800
CCl4
752
alanine
731
calcium
656
MDA
584
glutamate
546
nitric oxide
542
APAP
482
iron
472
potassium
452
phosphate
406
CAT
332
CAT
323
CAT
323
ammonia
295
phosphorus
291
methionine
273
zinc
265
acetate
249
ATP
234
cysteine
224
cadmium
224
copper
222
N-acetylcysteine
200
galactose
181
glutamine
172
selenium
163
hydrogen
163
2-oxoglutarate
158
nitrate
157
His
154
arginine
151
sulfate
139
methanol
138
GSSG
135
hyaluronic acid
129
PEG
121
3TC
120
NAD
112
CO2
111
leucine
106
chloroform
105
salt
100
alcohol dehydrogenase
100
DPPH
98
tyrosine
97
PEG
92
Silymarin
91
NAD
89
Asp
87
alloxan
87
ethyl acetate
84
ammonium
82
lysine
81
Curcumin
81
Insulin
79
dUTP
78
serine
77
MTT
77
NADPH
76
GTP
76
NADPH
76
Lactate
75
aniline
74
NH2
73
tryptophan
73
mercury
70
8-OHdG
70
aflatoxin B1
70
aspartic acid
69
tryptophan
67
H2O2
66
silver
66
ornithine
65
ornithine
65
ornithine
65
tryptophan
65
ornithine
65
ornithine
65
NADH
65
tryptophan
65
Hematoxylin
64
homocysteine
64
gallic acid
64
nicotinamide
63
Cholesterol
63
DMSO
63
Malondialdehyde
62
bromobenzene
61
ADP
61
Bilirubin
61
Phe
61
asparagine
60
Glutamate
60
vitamin D
60
threonine
59
glycerol
58
STZ
57
chromium
57
iodine
56
ADP
56
ADP
56
aldehyde
55
Cardiol
55
INH
53
Pac
52
caffeine
52
manganese
52
Alanine
51
Vitamin E
51
glutamic acid
49
6-12
48
Ile
48
DDP
48
Hemoglobin
48
proline
48
Ribavirin
48
Oil Red O
47
MCH
47
Lead
47
TSH
47
CdCl2
46
Ascorbic acid
46
valine
46
Arsenic
45
NADP
45
Melatonin
45
Abbott
45
CoA
44
phenol
44
TCA
44
Oil Red O
44
adenosylmethionine
44
isoleucine
43
isoleucine
43
AMP
43
Adriamycin
42
MIC
42
PMA
41
retinol
41
DBA
41
TAA
41
betaine
40
bromide
40
Quercetin
39
more...