Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:2.6.1.2 (alanine aminotransferase)
 26,722 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

2,4-Monofurfurylidene-tetra-O-methyl-sorbitol (MSF), which protects rats against a number of hepatotoxins, also reduces the death rate in mice receiving a crude Amanita phalloides powder (APP) by i.p. route, this protective effect being dose- and time-dependent. MSF-pretreatment greatly reduces APP-induced liver damage and blood serum GOT and GPT increase. MSF antagonizes APP more effectively than do mercaptopropionylglycine (MPG) and silymarin. The results are briefly discussed.
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PMID:Mice protection with 2,4-monofurfurylidene-tetra-O-methyl-sorbitol (MSF) against acute toxicity due to Amanita phalloides. 58 38