Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:2.6.1.2 (
alanine aminotransferase
)
26,722
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Gianotti-Crosti syndrome
(
GCS
) is a viral-associated eruption that most commonly occurs in children aged 15 months to 2 years. It consists of monomorphic red-brown to pink papules and vesicles distributed symmetrically on the cheeks, extensor surface of the extremities, and buttocks. The eruption usually spontaneously resolves over the course of 10 to 60 days. We report the rare case of
GCS
in an adult. An otherwise healthy 20-year-old woman presented with a pruritic eruption of 2 weeks' duration on the dorsal aspect of her hands and feet, elbows, and knees. The patient received oral corticosteroids prior to presentation to our clinic with some improvement. A biopsy revealed histopathologic findings consistent with a diagnosis of
GCS
. The patient's aspartate aminotransferase (AST) and
alanine aminotransferase
(
ALT
) levels were elevated. Over the course of the next 2 months, the patient's skin findings completely resolved with normalization of liver function tests. The clinical and histologic correlation was consistent with
GCS
in an adult. This condition may not be as rare in adults as previously thought. Clinicians should keep
GCS
in their differential diagnosis when examining adult patients.
...
PMID:Gianotti-Crosti syndrome: a case report in an adult. 2261 43
