Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: EC:2.6.1.19 (GABA transaminase)
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Human Gene/Protein
GABA transaminase 14.9
4-aminobutyrate aminotransferase 14.7
D-3-aminoisobutyrate-pyruvate aminotransferase 14.5
succinate-semialdehyde dehydrogenase 13.3
succinic semialdehyde dehydrogenase 13.2
succinate semialdehyde dehydrogenase 13.2
Succinate semialdehyde dehydrogenase 12.9
Alanine-glyoxylate aminotransferase 12.9
SSADH 12.2
alanine-glyoxylate aminotransferase 2 11.9
beta-ureidopropionase 11.9
glutamate decarboxylase GAD65 11.8
NAD+-isocitrate dehydrogenase 11.5
Succinic semialdehyde dehydrogenase 11.2
glutamate decarboxylase 11.0
formyltetrahydrofolate dehydrogenase 10.6
ALDH5A1 10.6
cysteine sulfinic acid decarboxylase 10.5
GAT-2 10.5
alpha-albumin 10.5
GAT2 10.3
GABA-B receptor 9.9
Ornithine aminotransferase 9.9
GABA transporter 9.9
AGT1 9.6
alanine-glyoxylate aminotransferase 9.6
betaine/GABA transporter 9.6
POP2 9.5
GAD1 9.5
KAT2 9.5
dihydrouracil dehydrogenase 9.4
PMCA3 9.4
cAMP-dependent protein kinase catalytic subunit 9.3
glutamic acid decarboxylase 9.3
V1a vasopressin receptor 9.3
PSORT 9.2
GAD67 9.1
GAT-3 9.1
Diamine oxidase 9.0
isocitric dehydrogenase 8.9
GABA 8.8
GAD 8.8
GAD2 8.8
2-oxoglutarate dehydrogenase 8.6
ubiquilin 8.6
alpha-ketoglutarate dehydrogenase 8.5
Glutaminase 8.5
ornithine aminotransferase 8.4
GAD65 8.3
DAO 8.3
GABA(B) receptor 8.2
agmatinase 8.2
dihydropyrimidinase 8.1
SV2A 8.1
PLP 8.1
PMCA2 8.1
arginine decarboxylase 8.0
propionyl-CoA carboxylase 8.0
pyrroline-5-carboxylate synthetase 8.0
BCATm 8.0
adenosine A2 receptor 8.0
oxoglutarate 7.9
glutaminase 7.9
diamine oxidase 7.8
S-adenosyl-L-methionine decarboxylase 7.8
gamma-amino butyric acid 7.7
serotonin N-acetyltransferase 7.7
noradrenaline transporter 7.7
gene 4 7.6
CPT1A 7.6
ZAP 7.6
pyridoxal kinase 7.6
beta-lyase 7.5
GTase 7.5
glutamic dehydrogenase 7.5
Tryptophan hydroxylase 7.5
polyamine oxidase 7.4
EOS 7.4
TC1 7.4
AMPS 7.3
HOT 7.2
Alanine aminotransferase 7.2
vesicular GABA transporter 7.2
Glutamic acid decarboxylase 7.2
glutamate dehydrogenase 7.2
EGR 7.1
FRS2 7.1
NFAT1 7.1
GAT1 7.1
HOP 7.1
GTA 7.1
CAO 7.1
glutamine synthetase 7.0
Glutamine synthetase 6.9
SPS 6.9
CPT1 6.9
phosphate-activated glutaminase 6.9
hydroxyindole-O-methyltransferase 6.9
S-adenosylhomocysteine hydrolase 6.9
ATP citrate lyase 6.8
prolyl endopeptidase 6.8
Dnmt3b 6.8
ABG 6.8
fumarase 6.7
vesicular glutamate transporter 2 6.7
GABA(A) receptor 6.7
5HT1A 6.6
CCK-4 6.6
carbamoylphosphate synthetase 6.6
CSD 6.6
DSP-4 6.5
acetyl-CoA synthetase 6.5
carnitine acetyltransferase 6.5
dopamine D4 receptor 6.5
ASP 6.5
decarboxylating 6.4
serine hydroxymethyltransferase 6.4
cannabinoid receptor 1 6.4
amine oxidase 6.3
GluR4 6.3
dihydroorotate dehydrogenase 6.2
mitochondrial carrier 6.2
COL3A1 6.1
dihydropyrimidine dehydrogenase 6.0
PTD 6.0
gephyrin 6.0
fragile X mental retardation protein 6.0
ODC 6.0
GDH 6.0
Nurr1 5.9
KCC2 5.9
dopa decarboxylase 5.9
ornithine decarboxylase 5.8
pyruvate carboxylase 5.8
aspartate aminotransferase 5.8
ChAT 5.8
H16 5.8
GES 5.8
SCH 5.8
aldehyde dehydrogenase 5.8
isocitrate dehydrogenase 5.7
POP 5.7
D-amino acid oxidase 5.7
ANT 5.7
HPI 5.6
adenosine A1 receptor 5.6
BAT 5.6
OMP 5.5
tryptophan hydroxylase 5.5
MAO-B 5.5
citrate synthase 5.5
A. nidulans 5.5
catechol-O-methyltransferase 5.5
SSA 5.5
Era 5.5
histamine H1 receptor 5.5
adenyl cyclase 5.4
glutamate pyruvate transaminase 5.3
vesicular monoamine transporter 2 5.3
DTNB 5.3
more...
Disease
Hyper-beta-alaninemia 13.7
Succinic semialdehyde dehydrogenase deficiency 12.6
audiogenic seizure 9.0
Acute encephalopathy 8.9
Medulla 8.7
GAD 8.4
catatonic schizophrenia 8.4
hyperglycinemia 8.1
hypo-osmolality 7.8
EOS 7.4
EOS 7.4
diabetic hyperglycemia 7.4
complex partial seizures 7.3
cocaine addiction 7.1
Lennox-Gastaut syndrome 7.1
ornithine transcarbamylase deficiency 7.0
petit mal 7.0
SPS 6.9
Lennox-Gastaut syndrome 6.8
aminoaciduria 6.6
SPS 6.5
propionic acidemia 6.5
premenstrual dysphoric disorder 6.4
hepatic coma 6.1
PME 6.1
PTD 6.0
moderate mental retardation 5.9
lymphogranuloma venereum 5.8
SCH 5.8
paranoid schizophrenia 5.7
Fallopian tube 5.7
catalepsy 5.6
generalized seizure 5.5
tardive dyskinesia 5.5
HCI 5.5
epilepsy 5.5
hyperosmolality 5.5
vitamin E deficiency 5.4
panic disorder 5.3
PIC 5.2
protein deficiency 5.2
GCE 5.2
fits 5.2
Venezuelan equine encephalitis 5.2
febrile convulsions 5.0
Rift Valley fever 4.8
porphyria 4.7
neoplastic process 4.7
cocaine abuse 4.7
anterior myocardial infarction 4.7
Wuchereria 4.7
disinhibition 4.7
CSA 4.5
Cerebellum 4.5
fragile X syndrome 4.5
tuberous sclerosis 4.4
developmental delay 4.3
Nelson 4.3
hyperprolactinemia 4.2
drug withdrawal 4.1
panic attacks 4.0
status epilepticus 4.0
brain atrophy 4.0
Cushing's disease 3.9
anhedonia 3.9
uterine leiomyoma 3.9
Huntington's disease 3.9
emotional stress 3.8
apraxia 3.8
HPA 3.8
listeriosis 3.8
African trypanosomiasis 3.7
ACP 3.7
fallopian tube 3.7
PCC 3.7
anxiety disorders 3.7
temporal lobe epilepsy 3.7
drug addiction 3.6
suicide 3.5
sleep disorders 3.5
meninges 3.4
encephalopathy 3.4
mental retardation 3.3
mental retardation 3.3
sexual dysfunction 3.2
hypoglycemia 3.2
movement disorder 3.1
brain metastases 3.1
PCA 3.1
MRS 3.1
parkinsonism 3.0
DBA 3.0
PSA 2.8
Pituitary 2.8
amnesia 2.8
sleep disturbances 2.8
migraine 2.8
affective disorder 2.8
psychosis 2.7
hyperphagia 2.7
tetanus 2.6
Hepatocellular carcinoma 2.6
NAME 2.6
PCP 2.5
astrocytoma 2.5
prematurity 2.5
iron deficiency 2.5
memory impairment 2.4
pheochromocytoma 2.4
hallucinations 2.4
schizophrenia 2.2
mole 2.1
ADHD 2.1
neurological disease 2.1
depression 2.0
Yersinia 2.0
mole 1.9
cold 1.8
prolapse 1.8
gastroesophageal reflux disease 1.7
myopathy 1.7
aggressiveness 1.7
SDS 1.6
ischemia 1.6
substance abuse 1.5
neuroblastoma 1.5
addiction 1.5
bipolar disorder 1.5
aggression 1.4
respiratory failure 1.4
myelodysplastic syndrome 1.4
coma 1.3
autism 1.3
cerebral ischemia 1.2
ulcerative colitis 1.2
alcoholism 1.1
amyotrophic lateral sclerosis 1.0
multiple sclerosis 0.9
Crohn's disease 0.9
Klebsiella 0.8
Alzheimer's disease 0.8
inflammatory bowel disease 0.8
Epstein 0.7
West 0.7
autoimmune disease 0.7
infertility 0.6
acute myocardial infarction 0.6
herpes simplex 0.5
hyperglycemia 0.4
tumor growth 0.4
glioma 0.4
dysplasia 0.3
osteoarthritis 0.2
hepatocellular carcinoma 0.1
cognitive impairment 0.1
Infection 0.0
malaria -0.2
virus infection -0.3
anemia -0.4
breast cancer -0.4
more...
Symptom
Subjective tinnitus 9.1
impaired motor coordination 7.7
tonic seizure 7.5
Psychiatric symptoms 6.9
POA 6.2
partial seizure 5.8
hypotonia 5.7
seizures 5.5
eds 5.2
neuralgia 4.5
myoclonus 4.2
skin irritation 4.2
bradykinesia 4.1
tachypnea 4.0
ataxia 3.9
lethargy 3.8
sleepiness 3.6
tinnitus 3.6
hypothermia 3.5
insomnia 3.5
spasticity 2.6
anorexia 2.5
starvation 2.2
dystonia 2.2
tremor 2.1
distraction 2.1
constipation 1.9
headache 1.8
agitation 1.7
analgesia 1.5
anesthesia 0.5
diarrhea -0.5
pain -0.7
Drug
Fengabine 12.9
GVG 12.7
Ganaxolone 10.9
Sodium valproate 9.5
Stiripentol 9.5
Rufinamide 9.4
Gabapentin 8.8
pyridoxal phosphate 8.6
Pyridoxal 8.2
Pyridoxal phosphate 8.1
Abamectin 8.1
Quisqualate 7.8
Aminoguanidine 7.5
Ethylenediamine 7.5
Compound 9 7.3
DPA 7.0
Apomorphine 6.6
Pregabalin 6.5
OMP 6.4
Glutamic acid 6.3
Sulpiride 6.0
Helium 6.0
Vitamin B 6.0
Pilocarpine 5.9
Kainic acid 5.9
Phenytoin 5.9
TEL 5.7
Isoniazid 5.3
niacin 5.0
ALA 4.8
balanced salt solution 4.7
Frontal 4.3
Propofol 4.2
CDP 4.1
L-tyrosine 4.1
NADH 3.8
Alanine 3.8
Ethanol 3.6
Vitamin E 3.6
lysine 3.4
PCP 3.4
Glucagon 3.4
CSF 3.2
citric acid 3.0
NH3 2.5
caffeine 1.9
Asn 1.7
Gel 1.4
vitamin E 1.2
Nephron 1.1
Leaf 0.9
ascorbate 0.8
Enzyme
GABA transaminase 15.3
D-3-aminoisobutyrate-pyruvate aminotransferase 14.7
EC 1.2.1.16 14.7
N-succinylglutamate 5-semialdehyde dehydrogenase 14.3
beta-alanine-pyruvate aminotransferase 14.3
EC 1.1.1.15 14.3
succinic semialdehyde dehydrogenase 13.3
EC 5.1.1.10 12.7
N-methylhydantoin amidohydrolase 12.7
delta-aminovalerate transaminase 12.7
hydroxyacid-oxoacid transhydrogenase 12.5
DABA DC 11.9
acetylornithine aminotransferase 11.9
transaminase C 11.6
lysine 2-monooxygenase 11.6
3'(2'),5'-bisphosphate nucleotidase 11.6
beta-ureidopropionase 11.5
YdcW 11.5
2-oxoglutarate decarboxylase 11.4
Xsc 11.3
glutamate decarboxylase 11.1
YgjG 10.9
alpha-aminoadipate aminotransferase 10.9
PrpD 10.8
methylmalonate-semialdehyde dehydrogenase 10.3
SOAT 10.2
propionyl-CoA synthetase 10.1
leucine aminotransferase 10.1
D-amino acid aminotransferase 9.8
desulfinase 9.8
glutamine transaminase K 9.6
pantothenate synthetase 9.3
ornithine aminotransferase 9.1
branched-chain aminotransferase 9.0
isoflavone reductase 9.0
alanine racemase 8.5
glutamic dehydrogenase 8.5
L-serine dehydratase 8.4
alpha-ketoglutarate dehydrogenase 8.4
phosphoserine aminotransferase 8.3
arginine decarboxylase 8.2
dihydropyrimidinase 8.1
arginine decarboxylase 8.0
propionyl-CoA carboxylase 7.9
propionyl-CoA carboxylase 7.8
kynurenine aminotransferase 7.8
glutaminase 7.8
adenylosuccinate lyase 7.7
succinyl-CoA synthetase 7.6
aspartase 7.5
NAD+ oxidoreductase 7.5
pyridoxal kinase 7.5
polyamine oxidase 7.4
glutamate dehydrogenase 7.3
glutamate dehydrogenase 7.3
glutamate dehydrogenase 7.3
condensing enzyme 7.2
dihydropyrimidine dehydrogenase 7.2
diamine oxidase 7.2
SpeB 7.2
S-adenosylmethionine decarboxylase 7.1
LuxS 7.1
proline dehydrogenase 7.0
glutamine synthetase 7.0
4CL 6.9
arylalkylamine N-acetyltransferase 6.9
tryptophanase 6.8
AGT 6.7
SPS 6.6
lysine decarboxylase 6.6
dihydropyrimidine dehydrogenase 6.6
carnitine acetyltransferase 6.5
cyclohydrolase 6.5
acetyl-CoA synthetase 6.4
acetate kinase 6.4
dihydroorotate dehydrogenase 6.3
dihydroorotate dehydrogenase 6.3
SCS 6.3
isocitrate dehydrogenase 6.3
malate synthase 6.3
DOPA decarboxylase 6.2
aromatic L-amino acid decarboxylase 6.2
fumarase 6.1
monoamine oxidase 6.1
serine hydroxymethyltransferase 6.1
fumarate reductase 6.0
tyrosine aminotransferase 5.9
ornithine decarboxylase 5.8
aldehyde dehydrogenase 5.8
aldehyde dehydrogenase 5.8
aldehyde dehydrogenase 5.7
pyruvate carboxylase 5.7
glutamate synthase 5.7
glutamate synthase 5.7
ascorbate oxidase 5.7
TMT 5.6
prolyl endopeptidase 5.6
glutamate synthase 5.6
BAT 5.6
aldehyde dehydrogenase 5.5
isocitrate dehydrogenase 5.5
tryptophan 2,3-dioxygenase 5.5
tryptophan hydroxylase 5.5
citrate synthase 5.5
aspartate aminotransferase 5.4
MPP 5.4
isocitrate lyase 5.3
choline acetyltransferase 5.2
aldehyde dehydrogenase 5.2
N-acetyltransferase 5.1
alanine aminotransferase 5.0
CPS 5.0
transketolase 4.9
tyrosine hydroxylase 4.9
dopamine beta-hydroxylase 4.8
histidine decarboxylase 4.7
malate dehydrogenase 4.7
succinate dehydrogenase 4.6
aryl hydrocarbon hydroxylase 4.6
phosphoenolpyruvate carboxylase 4.5
deaminase 4.5
ornithine transcarbamylase 4.5
MAT 4.5
succinic dehydrogenase 4.5
aconitase 4.5
hexokinase 3.9
pyruvate dehydrogenase 3.8
pyruvate dehydrogenase 3.5
pyruvate dehydrogenase 3.5
thymidylate synthase 3.5
nitrate reductase 3.4
nitrate reductase 3.4
nitrate reductase 3.4
nitrate reductase 3.4
arginase 3.4
nitrate reductase 3.4
carbonic anhydrase 3.4
PCP 3.4
adenylate cyclase 3.4
nitrate reductase 3.4
NADPH-diaphorase 3.3
NO synthase 3.3
acetylcholinesterase 3.3
phosphoenolpyruvate carboxykinase 3.2
phosphoenolpyruvate carboxykinase 3.2
CPT 3.1
phosphoenolpyruvate carboxykinase 3.1
CD10 3.0
DNA methyltransferase 3.0
pyruvate kinase 2.9
NADPH oxidase 2.8
dihydrofolate reductase 2.8
phosphoinositide 3-kinase 2.7
kallikrein 2.7
AST 2.7
ATP synthase 2.5
NOS 2.4
lactate dehydrogenase 2.4
beta-galactosidase 2.4
glucose-6-phosphate dehydrogenase 2.3
more...
Compound
3-phenylpentanoic acid 15.3
3-phenylpentanoic acid 15.3
1-cyclopentene-1-carboxylic acid 14.3
Gabaculine 13.5
3-chloroalanine 12.9
3-chloroalanine 12.9
3-chloropropanoic acid 12.9
Vigabatrin 12.7
3-methyl-2-butenoic acid 12.5
3-chloro-D-alanine 11.9
AZU 11.9
2-aminoethylphosphonic acid 11.6
Canaline 11.1
TXP 11.0
2-pentenoic acid 10.9
Homotaurine 10.8
beta-methylcrotonic acid 10.7
Phenelzine 10.6
Phenelzine 10.5
THIP 10.4
Glutaric acid 10.2
5-aminovalerate 9.9
4-methylpentanoic acid 9.8
Pyrithiamine 9.7
4-hydroxybenzyl alcohol 9.7
Semicarbazide 9.7
cinnamyl acetate 9.5
Tiagabine 9.5
gamma-aminobutyric acid 9.5
1-penten-3-ol 9.2
2-butenoic acid 9.2
4-hydroxybenzaldehyde 9.1
4-hydroxybenzaldehyde 9.1
4-hydroxybenzaldehyde 9.1
4-hydroxybenzaldehyde 9.1
4-hydroxy-3-methoxybenzaldehyde 9.1
4-hydroxy-3-methoxybenzaldehyde 9.1
DBB 9.0
2-butenoic acid 8.9
XTP 8.9
GABA 8.9
Ethosuximide 8.9
4-hydroxybenzaldehyde 8.9
GABA 8.9
beta-alanine 8.9
2-oxoglutarate 8.8
Muscimol 8.8
PMP 8.7
PMP 8.7
2-Chloroadenosine 8.7
2-Chloroadenosine 8.7
4-oxobutanoic acid 8.7
4-hydroxy-3-methoxybenzaldehyde 8.6
PMP 8.5
HBA 8.5
2-hydroxybenzaldehyde 8.4
2-hydroxybenzaldehyde 8.4
2-hydroxybenzaldehyde 8.4
2-hydroxybenzaldehyde 8.4
2-hydroxybenzaldehyde 8.4
2-hydroxybenzaldehyde 8.4
2-hydroxybenzaldehyde 8.4
2-hydroxybenzaldehyde 8.4
2-hydroxybenzaldehyde 8.4
2-hydroxybenzaldehyde 8.4
2-hydroxybenzaldehyde 8.4
2-hydroxybenzaldehyde 8.4
2-hydroxybenzaldehyde 8.4
2-hydroxybenzaldehyde 8.4
2-hydroxybenzaldehyde 8.4
2-hydroxybenzaldehyde 8.4
2-hydroxybenzaldehyde 8.4
3-methylcrotonyl-CoA 8.4
Roxarsone 8.3
Piperidine 8.3
Pyridoxal 8.2
gamma-hydroxybutyric acid 8.2
2-hydroxybenzaldehyde 8.2
Felbamate 8.1
Amitraz 8.1
Clobazam 8.1
2-hydroxybenzaldehyde 8.1
PLP 8.0
1-aminocyclopropanecarboxylic acid 7.9
Bicuculline 7.9
2-furaldehyde 7.9
2-hydroxybenzaldehyde 7.8
vinyl 7.8
Lamotrigine 7.7
Tetracaine 7.7
3-methylbutanoic acid 7.7
pentanedioic acid 7.7
Hydrazine 7.7
Oxcarbazepine 7.7
2-hydroxybenzaldehyde 7.4
EOS 7.4
Vanillin 7.4
Baclofen 7.3
2-oxobutyrate 7.3
oxalacetate 7.3
Picrotoxin 7.3
Picrotoxin 7.3
Flumazenil 7.3
Levetiracetam 7.3
isonicotinic acid 7.3
Valproic acid 7.3
Valproic acid 7.2
Lithium chloride 7.2
2-pyrrolidinone 7.1
Cypermethrin 7.1
AIB 7.0
2-oxobutyrate 7.0
2-phenylethylamine 6.9
hydroxyglutarate 6.9
Putrescine 6.9
Chlordiazepoxide 6.9
DPA 6.8
DPA 6.8
Pyridoxine 6.7
Polyamine 6.7
Pyrroloquinoline quinone 6.6
2-furaldehyde 6.6
Agmatine 6.6
DPA 6.6
Ornithine 6.6
DPA 6.6
Ether 6.6
Ether 6.5
DPA 6.5
Lorazepam 6.5
Clonazepam 6.5
2-pyrrolidinone 6.4
phenylacetaldehyde 6.4
DPA 6.4
Baicalein 6.4
butyric acid 6.3
DPA 6.3
OMP 6.3
DPA 6.3
DPA 6.3
DPA 6.3
DPA 6.3
DPA 6.3
Carnosine 6.2
butyric acid 6.2
aminomethyl 6.2
4-hydroxyphenylacetic acid 6.2
Aminophylline 6.2
CPP 6.2
succinic acid 6.1
succinic acid 6.1
succinic acid 6.1
succinic acid 6.1
ornithine 6.1
ornithine 6.1
ornithine 6.1
CPP 6.1
ornithine 6.1
ornithine 6.1
3-hydroxybutyric acid 6.1
more...