Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:2.6.1.1 (aspartate aminotransferase)
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Human Gene/Protein
transducin-like enhancer protein 10.5
Chloride intracellular channel protein 2 10.5
LRFT 10.5
ubiquitin-conjugating enzyme E2Z 10.5
spliceosome associated protein 10.5
LC27 10.5
splicing factor arginine/serine-rich 6 10.5
natural killer cell receptor 2B4 10.5
IGSF22 10.5
Ferritin light polypeptide 10.5
VCX protein 10.5
aspartate aminotransferase 10.5
AST 10.5
AAT 10.3
alanine aminotransferase 9.6
GOT1L1 9.5
aat-1 9.5
ZNF193 9.5
creatine kinase, mitochondrial 9.5
CCDC43 9.5
mitochondrial glycerol 3-phosphate acyltransferase 9.5
TPARL 9.5
Cell death activator 9.5
glutamate pyruvate transaminase 9.4
AAT1 9.3
AAT-1 9.3
Alanine aminotransferase 9.0
C6orf120 8.9
SSB3 8.9
SET nuclear oncogene 8.9
aspartate aminotransferase 1 8.9
Erbb2 interacting protein 8.9
actin, alpha 2, smooth muscle, aorta 8.9
Aspartate aminotransferase 8.6
GGT 8.5
GPT2 8.5
SID1 transmembrane family member 2 8.5
GGT 2 8.5
enoyl-Coenzyme A, hydratase/3-hydroxyacyl Coenzyme A dehydrogenase 8.5
CCBL2 8.5
CTXL 8.5
AD031 8.5
ALP 8.2
GGT6 8.2
myristoyl CoA:protein N-myristoyltransferase 8.2
Ribosomal protein S27a 8.2
mitochondrial solute carrier protein 8.2
RRP2 8.2
Small ubiquitin-like modifier 4 8.2
alpha-1 globin 8.2
gamma-glutamyltransferase 8.2
GOT1 8.2
Aspartate transaminase 8.0
Gamma-glutamyltransferase 7.9
ST6GALNAC3 7.9
GP110 7.9
PGBD1 7.9
Insulin-like growth factor binding protein 1 7.9
aspartate dehydrogenase 7.9
myosin light chain 3 7.8
ALB 7.8
SAMM50 7.8
FABPpm 7.7
dihydrolipoamide S-succinyltransferase 7.7
INCLUDED 7.7
TRIM40 7.7
LDHL 7.7
protein kinase C, epsilon 7.7
Apolipoprotein O 7.7
Nucleoside diphosphokinase 7.7
glycerol-3-phosphate acyltransferase, mitochondrial 7.7
MP100 7.6
AAAT 7.5
GLT25D1 7.5
collagen, type I, alpha 1 7.5
PARVB 7.5
PPP1R3G 7.5
zinc transporter 5 7.5
Alanine-glyoxylate aminotransferase 7.5
paraoxonase-3 7.5
more...
Disease
cardiopericarditis 10.5
Cholemic nephrosis 10.5
AAT5 10.5
Midzonal hepatic necrosis 10.5
AAT3 9.5
Pigment nephropathy 9.5
Cytomegalovirus syndrome 9.5
AAT2 9.5
Exudative diathesis 8.9
Cold Ischemia 8.9
Hyperprolinemia type II 8.9
Acute toxic hepatitis 8.7
Tying-up 8.5
Alcoholic liver damage 8.2
Round heart disease 8.2
Erythrocytopenia 8.2
Estrogenic effect 8.2
Ischemic hepatitis 8.1
SPD2 7.9
Compensated metabolic acidosis 7.9
Secondary biliary cirrhosis 7.9
mercaptolactate-cysteine disulfiduria 7.9
Erythroid hypoplasia 7.9
AAT1 7.8
Hepatotoxicity 7.8
Boid inclusion body disease 7.7
Regenerative anemia 7.7
Recurrent upper respiratory tract infections 7.7
AAT deficiency 7.6
SPD1 7.5
Hepatic necrosis 7.4
Coronary artery anomaly 7.4
relapsed small lymphocytic lymphoma 7.4
Jordan's anomaly 7.4
Transient hypogammaglobulinemia of infancy 7.4
Autoimmune hypothyroidism 7.4
Carrion 7.3
Toxicosis 7.2
Drug-induced myopathy 7.2
Corneal deposits 7.2
FENIB 7.2
ASAT 7.1
Heartworm disease 7.1
Micronodular cirrhosis 7.1
FAA4 7.0
Hepatic infarction 7.0
EBV hepatitis 7.0
Myoglobinuric acute renal failure 6.9
MRSA wound infection 6.9
Hepatic impairment 6.9
Fulminant hepatitis 6.8
Alcoholic liver disease 6.8
GTRAP3-18 6.8
liver fibrosis 6.8
Necrobacillosis 6.7
MRX34 6.7
Simian hemorrhagic fever 6.7
Acute liver failure 6.7
Neutrophilic panniculitis 6.6
Chronic iron overload 6.6
Ascending cholangitis 6.6
Renal anemia 6.6
vitamin B6 deficiency 6.6
alcoholic fatty liver 6.5
Intestinal coccidiosis 6.5
Retinoic acid syndrome 6.5
Chlamydia trachomatis pneumonia 6.5
Hepatosplenic schistosomiasis 6.5
GSD IX 6.4
heterophyiasis 6.4
PPD2 6.4
CMV hepatitis 6.3
cholangiolitis 6.3
Unconjugated hyperbilirubinemia 6.3
porcine stress syndrome 6.2
Nonalcoholic fatty liver 6.2
Cytokine storm 6.2
Acute hepatitis A 6.2
Conjugated hyperbilirubinemia 6.2
Dicrocoeliosis 6.2
more...
Symptom
jaundice of the skin 8.5
liver pain 7.5
ECG signs of myocardial ischemia 6.4
Limb weakness 6.4
rib pain 6.1
frequent urination 5.7
feeling sick 5.7
Murphy's sign 5.6
strangury 5.4
breast hyperplasia 5.4
dark urine 5.4
hepatomegaly 5.4
sinus congestion 5.2
hypoproteinemia 5.0
Reticulocytosis 4.9
emaciation 4.7
Flu-like symptoms 4.7
lassitude 4.7
right upper quadrant pain 4.7
periorbital edema 4.5
decreased appetite 4.5
bradypnea 4.5
generalized rash 4.4
Breast pain 4.3
Muscle soreness 4.3
Kayser-Fleischer ring 4.3
corpulence 4.3
lethargy 4.2
anorexia 4.2
myalgia 4.0
gumma 4.0
asterixis 3.8
No adverse effect 3.8
oliguria 3.8
Aphasic 3.8
ketonuria 3.7
nocturnal cough 3.7
asthenia 3.7
splenomegaly 3.6
prostration 3.6
hepatosplenomegaly 3.5
incoordination 3.5
bigeminal 3.5
chills 3.5
abdominal cramps 3.5
loss of equilibrium 3.4
non-productive cough 3.4
nausea 3.3
polydipsia 3.3
nasal discharge 3.3
rigors 3.2
stomach pain 3.1
meningism 3.1
polyuria 3.1
abdominal discomfort 3.1
Decreased activity 3.0
hangover 3.0
epigastric pain 3.0
jaw pain 3.0
hyperemesis gravidarum 3.0
arm weakness 3.0
Tenderness 3.0
vomiting 2.9
impaired motor coordination 2.9
excessive sweating 2.9
consciousness disturbance 2.8
labored breathing 2.8
rales 2.8
pedal edema 2.8
muscle rigidity 2.8
diarrhea 2.8
arthralgia 2.8
inanition 2.7
abdominal pain 2.7
muscle cramps 2.7
Spots 2.7
ACHE 2.6
night sweats 2.6
nausea and vomiting 2.6
fatigue 2.6
more...
Drug
Polygonatum rhizome 10.5
Plantago seed 10.5
Cholic Acid 9.5
Sulfopyruvate 9.2
Schisandra fruit 9.2
Timefurone 8.9
Gamma-Glutamylcysteine 8.9
Somidobove 8.9
Glibornuride 8.5
Erythromycin acistrate 8.2
Valerianae radix 7.7
Bidisomide 7.5
Propagermanium 7.5
Gemifloxacin mesylate 7.4
Bupleurum root 7.4
Dexamethasone palmitate 7.2
Monensin sodium 7.2
Cupric chloride 6.9
Lifibrol 6.8
Sesame oil 6.8
Tocopherol acetate 6.7
Pyridoxal phosphate 6.7
pyridoxal phosphate 6.6
Zinga 6.6
Cupric sulfate 6.5
Innohep 6.4
Citrus unshiu peel 6.4
Tiopronin 6.4
Questran 6.4
Tranexamic Acid 6.3
Pyridoxal 6.2
Darapladib 6.1
Metreleptin 6.1
NAH 6.1
Mercurochrome 6.1
Cognex 5.9
Alendronate sodium 5.9
Tepoxalin 5.9
Uzel 5.8
Calciparine 5.8
Berberine chloride 5.8
Gliquidone 5.8
CTT 5.7
Malotilate 5.7
Maduramicin 5.7
Sesamol 5.7
Menogaril 5.6
Pralatrexate 5.6
Manganese chloride 5.6
Bosutinib 5.6
Lead acetate 5.5
Gentian 5.5
Imagent 5.5
Tryptophane 5.5
Aescin 5.4
Swertia 5.4
AGG 5.4
Vitamin B 5.4
Lisdexamfetamine dimesylate 5.4
Histidinol 5.3
Ilomastat 5.3
Glucose-6-Phosphate 5.2
Bucillamine 5.2
Dipyrone 5.2
Peramivir 5.2
TAC 5.2
Telbivudine 5.2
Toltrazuril 5.2
Estrumate 5.2
Prolastin 5.2
Dimethylformamide 5.2
Swainsonine 5.1
Amlexanox 5.1
Serum albumin 5.1
Rocaltrol 5.0
Progabide 5.0
O-Acetylserine 5.0
Entecavir 5.0
Entecavir 5.0
Clofarabine 5.0
more...
Enzyme
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate-2,6-diaminopimelate ligase 10.5
aspartate-prephenate aminotransferase 10.5
glucose phosphomutase 10.5
aspartate aminotransferase 10.5
AST 10.5
EC 2.3.1.2 9.5
alanine aminotransferase 9.5
D-amino acid aminotransferase 8.9
aromatic amino acid aminotransferase 8.8
aryl sulfotransferase IV 8.7
CobD 8.7
succinyldiaminopimelate aminotransferase 8.5
EC 2.6.1.14 8.5
sulfopyruvate decarboxylase 8.2
histidinol phosphate aminotransferase 8.2
gamma-glutamyl transpeptidase 7.9
aspartate dehydrogenase 7.9
BAST I 7.7
amine N-sulfotransferase 7.7
glutamine transaminase K 7.7
EC 2.6.1.4 7.6
valine dehydrogenase 7.6
glutamic dehydrogenase 7.5
sorbitol dehydrogenase 7.4
glutamate dehydrogenase 7.2
glutamate dehydrogenase 7.2
2-oxoisovalerate dehydrogenase 7.2
guanosine deaminase 7.2
ferric leghemoglobin reductase 7.2
pyruvate aldolase 7.2
glutamate dehydrogenase 7.2
lactate dehydrogenase 7.1
desulfinase 7.0
creatine kinase 7.0
transaminase C 6.8
pyridoxal oxidase 6.8
alkaline phosphatase 6.8
proprotein convertase 2 6.7
L-asparagine synthetase 6.7
EC 2.3.2.1 6.7
branched-chain aminotransferase 6.7
malate dehydrogenase 6.6
glycocyamine kinase 6.5
glutaminase II 6.4
MDH 6.4
phosphoserine aminotransferase 6.4
AGT 6.4
guanase 6.4
MDH 6.3
enzyme X 6.2
glutathione oxidase 6.2
mannitol 1-phosphate dehydrogenase 6.2
glutathione peroxidase 6.1
collagen galactosyltransferase 6.1
alpha-aminoadipate aminotransferase 6.1
EC 1.1.1.38 6.1
PrpD 6.1
tyrosine aminotransferase 6.1
CGT 6.1
arogenate dehydrogenase 5.9
GMT 5.9
threonine aldolase 5.9
isocitrate dehydrogenase 5.8
glycine dehydrogenase 5.8
EC 2.3.1.29 5.8
glycine dehydrogenase 5.8
transpeptidase 5.8
superoxide dismutase 5.8
asparagine synthetase 5.8
aspartase 5.8
lactic acid dehydrogenase 5.8
8-amino-7-oxononanoate synthase 5.8
4-nitrophenol hydroxylase 5.8
glutaminase 5.8
arylsulfate sulfotransferase 5.7
glutamate synthase 5.7
ornithine aminotransferase 5.7
delta-aminolevulinic acid dehydratase 5.7
aspartate racemase 5.7
LGT 5.7
more...
Compound
N,N-dimethylhydrazinecarboxamide 10.5
Eremanthin 10.5
2,3-dibromo-2-butenoic acid 10.5
(Benzamidooxy)acetic acid 10.5
2-amino-3-butenoic acid 10.5
Perfluorosuccinate 10.5
2-mercapto-N-phenylacetamide 10.5
3-mercapto-N-phenylpropanamide 10.5
AAT 10.5
Usaramine 9.5
2-amino-4-methoxy-4-oxobutanoic acid 9.5
2-amino-4-methoxy-4-oxobutanoic acid 9.5
Interferon gamma-1b 9.5
1-dotriacontanol 9.5
Gostatin 8.9
2-methylaspartic acid 8.9
Cupressuflavone 8.9
Diphenaldehyde 8.9
Sequoyitol 8.9
Coleonol 8.9
S-(2-aminoethyl)cysteine 8.7
S-(2-aminoethyl)cysteine 8.7
S-(2-aminoethyl)cysteine 8.7
Avenaciolide 8.5
4-methoxy-1-naphthaldehyde 8.5
Pachyman 8.5
butyl palmitate 8.5
Murrayanine 8.5
Fraxin 8.4
3-sulfopyruvate 8.4
Canaline 8.4
ALP 8.2
3-chloroalanine 8.2
C6H5NO3 8.2
Astragaloside III 8.2
Sulfometuron methyl 8.2
3-chloroalanine 8.2
Robinin 8.2
Ophthalmic acid 8.2
PTGA 8.2
3-mercaptolactate-cysteine disulfide 8.2
Robinin 8.2
Pyridoxamine 5'-phosphate 8.1
Dictamnine 8.0
4-methoxy-1-naphthaldehyde 7.9
Yangonin 7.9
Pedunculagin 7.9
Succinic acid monomethyl ester 7.9
arginine succinate 7.9
Cronolone 7.9
Indoxyl sulfate 7.9
Taraxasterol 7.8
Lead nitrate 7.8
AAFC 7.7
Vicine 7.7
Dimethyl phosphate 7.7
Columbin 7.7
Yangonin 7.7
Fraxetin 7.6
(aminooxy)acetic acid 7.6
D-Galactosamine 7.6
Irisolidone 7.5
Citramalate 7.5
Tellimagrandin I 7.5
Tetrachloride 7.5
bicyclo[2.2.1]heptan-2-one 7.5
Cinobufotalin 7.5
Allyl methyl disulfide 7.5
Citramalate 7.5
CCl4 7.4
Trithion 7.4
4-(diethylamino)benzaldehyde 7.4
Budlein A 7.4
1-phenyl-2-propen-1-one 7.4
Propagermanium 7.4
Girinimbine 7.4
alpha-Methyltryptophan 7.4
Karanjin 7.2
Tectorigenin 7.1
Diphenyl ditelluride 7.1
more...