Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:2.6.1.1 (aspartate aminotransferase)
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Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
aspartate aminotransferase 14774
alanine aminotransferase 7069
AST 6040
alkaline phosphatase 3556
lactate dehydrogenase 2397
albumin 1860
superoxide dismutase 1735
GSH 1560
Sep 1485
catalase 1353
creatine kinase 1262
glutathione peroxidase 1039
TNF 1031
ALP 874
AAT 845
Mol 791
LDH 782
hemoglobin 778
tumor necrosis factor 744
insulin 739
SOD 598
IL-6 596
GGT 509
caspase-3 497
glutamate pyruvate transaminase 462
lipopolysaccharide 461
HDL 454
cytokine 426
glutamate dehydrogenase 420
prothrombin 400
collagen 398
gamma-glutamyltransferase 385
CAT 340
C-reactive protein 324
glutathione reductase 319
serum albumin 306
myeloperoxidase 299
galactosamine 290
amylase 286
inducible nitric oxide synthase 282
gamma-glutamyl transpeptidase 280
interleukin-6 277
Bcl-2 255
interferon 249
malate dehydrogenase 231
glutathione S-transferase 224
IL-10 220
IFN 216
GTG 214
ATP 210
acid phosphatase 198
LPS 181
Alanine aminotransferase 177
antioxidant enzyme 177
Nrf2 172
ferritin 172
gut 166
SMA 163
TLR4 156
cytochrome P450 155
endoplasmic reticulum 152
microsomal 152
lipase 151
fibrinogen 151
heme oxygenase-1 149
ROS 143
CYP2E1 142
p65 140
GST 139
tumor necrosis factor alpha 134
erythroid 132
serum protein 131
p53 130
TNF-alpha 130
FIB 129
transferrin 125
sorbitol dehydrogenase 123
surface antigen 123
acetylcholinesterase 121
She 118
more...
Disease
GSH 1560
liver disease 836
cirrhosis 799
cancer 771
hepatitis 749
ischemia 649
fatty liver 640
liver fibrosis 635
diabetes 631
tumor 593
hepatocellular carcinoma 556
chronic hepatitis 535
hepatitis C 465
hepatitis B 452
obesity 386
cholestasis 302
cold 259
anemia 254
sepsis 238
hypertension 235
thrombocytopenia 232
sepsis 226
alcoholic fatty liver 225
myocardial infarction 206
viral hepatitis 202
type 2 diabetes 201
depression 193
chronic liver disease 190
hyperlipidemia 188
metabolic syndrome 178
Nonalcoholic fatty liver 176
HIV 164
acute hepatitis 155
hyperglycemia 154
liver cancer 146
virus infection 135
acute myocardial infarction 128
alcoholism 124
rash 122
cardiovascular disease 118
carcinoma 117
dyslipidemia 113
Hepatotoxicity 113
breast cancer 108
hypercholesterolemia 106
primary biliary cirrhosis 99
infectious diseases 99
atherosclerosis 97
leukopenia 97
alcohol abuse 97
pneumonia 96
neutropenia 94
liver cancer 92
pruritus 92
hypoglycemia 91
immunodeficiency 87
renal failure 87
hyperbilirubinemia 87
myopathy 85
tuberculosis 85
hepatitis A 85
carcinogenesis 84
renal disease 81
proteinuria 81
chronic active hepatitis 81
myocardial ischemia 79
dehydration 78
AAT deficiency 75
viremia 75
malnutrition 72
portal hypertension 71
encephalopathy 71
stroke 69
tumor growth 69
iron overload 69
dengue 68
lymphoma 68
heart failure 66
rheumatoid arthritis 66
cholangitis 66
more...
Symptom
diarrhea 267
fatigue 209
pain 183
anorexia 170
vomiting 167
hepatomegaly 162
nausea 160
anesthesia 148
abdominal pain 139
weakness 101
splenomegaly 82
overweight 81
headache 73
myalgia 73
lethargy 71
cough 69
dyspnea 66
seizures 61
hypothermia 48
nausea and vomiting 40
starvation 40
erythema 39
Ill 36
chest pain 35
hepatosplenomegaly 35
arthralgia 33
respiratory distress 33
chills 33
ataxia 31
collapse 29
exhaustion 28
hypoproteinemia 25
constipation 25
flushing 24
asthenia 23
angina 20
emaciation 19
epigastric pain 19
polyuria 18
decreased appetite 18
oliguria 17
tremor 16
analgesia 15
polydipsia 15
dizziness 15
discomfort 14
discomfort 14
insomnia 14
incoordination 14
sleepiness 13
right upper quadrant pain 12
colic 12
paresis 11
acute stress 11
shortness of breath 11
back pain 11
sore throat 11
functional recovery 11
abdominal discomfort 10
agitation 10
acidity 10
nasal discharge 9
pallor 9
tachypnea 9
cyanosis 9
cachexia 9
regurgitation 9
hypotonia 9
dark urine 8
apathy 8
skin irritation 8
hyperoxia 8
thinning 6
frequent urination 6
fever of unknown origin 6
exertional dyspnea 6
hypercapnia 5
night sweats 5
bone pain 5
bloating 5
more...
Drug
vitamin E 240
ascorbate 202
pyridoxal phosphate 171
ROS 143
lysine 126
Ethanol 94
NADH 90
IL-2 83
Asn 66
Monit 65
Cardiovasc 60
Albumin 58
ROC 49
Glutathione 48
IFN-gamma 45
Alanine 44
Vitamin E 43
CTX 41
TAC 40
CSF 40
Portal 38
Vitamin B 35
ALA 35
caffeine 35
Dermatol 33
ACT 33
TAT 30
citric acid 29
Serum albumin 28
Bifidobacterium 28
MAP 27
Leaf 25
niacin 23
AGG 23
CTC 22
lactose 22
Nephron 22
Nephron 22
Dial 21
CTC 21
TTC 20
CTX 19
Heme 19
CTX 19
ZnO 18
Glycyrrhiza 18
CCL 18
Fructose 16
Gel 15
ampicillin 15
ENT 15
EE2 15
CTT 15
NH3 15
Ginseng 14
Isoniazid 13
Rutin 13
Pyridoxal 13
Acacia 13
Tacrolimus 13
Ringer's solution 12
Monensin 12
NAG 11
TiO2 11
Aloe 11
L-tyrosine 10
Simvastatin 10
Pyridoxal phosphate 10
Norplant 9
CTA 9
Rosiglitazone 9
PCB 9
TAK 9
Isotretinoin 9
Biopolymers 9
Prednisolone 9
Emodin 8
Emodin 8
Fraction 8
Adriamycin 8
more...
Enzyme
aspartate aminotransferase 21665
alanine aminotransferase 13093
AST 6039
alkaline phosphatase 3559
lactate dehydrogenase 2637
superoxide dismutase 2253
catalase 1658
creatine kinase 1617
gamma-glutamyl transpeptidase 1479
glutathione peroxidase 1054
glutamate dehydrogenase 443
glutamate dehydrogenase 440
glutamate dehydrogenase 438
peroxidase 379
caspase-3 374
glutathione S-transferase 366
glutathione reductase 320
malate dehydrogenase 294
acetylcholinesterase 277
mitogen-activated protein kinase 268
cholinesterase 205
acid phosphatase 198
lipase 160
glucose-6-phosphate dehydrogenase 140
ERK 131
AMP-activated protein kinase 128
sorbitol dehydrogenase 124
ATPase 120
isocitrate dehydrogenase 120
glutamine synthetase 116
protein kinase 108
isocitrate dehydrogenase 107
thromboplastin 107
lysozyme 104
phosphoenolpyruvate carboxykinase 98
phosphoenolpyruvate carboxykinase 98
aldolase 98
phosphoenolpyruvate carboxykinase 96
alcohol dehydrogenase 80
citrate synthase 79
pyruvate kinase 78
hexokinase 75
AMPK 74
glucose-6-phosphatase 73
focal adhesion kinase 72
AMPK 71
glutaminase 70
xanthine oxidase 68
succinate dehydrogenase 68
collagenase 65
trypsin 63
NQO1 62
ceruloplasmin 61
tyrosine aminotransferase 59
caspase-9 58
transpeptidase 56
arginase 53
luciferase 52
reverse transcriptase 49
acetyl-CoA carboxylase 48
MDH 45
MDH 45
AGT 43
aldehyde dehydrogenase 43
heme oxygenase 42
phosphoglucose isomerase 41
demethylase 41
alpha-amylase 40
neutrophil elastase 39
6-phosphogluconate dehydrogenase 38
6-phosphogluconate dehydrogenase 38
pyruvate carboxylase 38
CYP3A4 36
phosphoenolpyruvate carboxylase 36
PARP 35
leucine aminopeptidase 35
alpha-ketoglutarate dehydrogenase 35
CPT 35
beta-glucuronidase 35
cytochrome oxidase 35
more...
Compound
glucose 2464
creatinine 2388
urea 2191
GSH 1597
GSH 1597
Clin 1488
Dec 1481
water 1181
nitrogen 1062
TNF 1031
DNA 989
alanine 881
Pac 874
ALP 874
oxygen 852
sodium 844
AAT 841
calcium 797
ethanol 769
phosphate 642
MDA 562
potassium 558
CCl4 553
glutamate 538
nitric oxide 486
iron 396
phosphorus 394
CAT 348
CAT 340
CAT 340
APAP 308
ammonia 294
2-oxoglutarate 275
acetate 257
zinc 242
cysteine 234
copper 228
methionine 220
hydrogen 219
ATP 210
sulfate 198
arginine 198
glutamine 197
lysine 182
selenium 179
cadmium 168
galactose 162
tyrosine 146
Asp 144
His 143
leucine 142
methanol 140
hyaluronic acid 133
N-acetylcysteine 129
Phe 128
salt 122
nitrate 120
NAD 118
GPT 111
CO2 108
serine 107
ammonium 101
GSSG 100
NAD 97
DPPH 94
NADH 90
Lactate 86
MTT 85
tryptophan 84
PEG 83
tryptophan 82
NH2 82
ethyl acetate 81
tryptophan 80
tryptophan 80
NADP 79
alcohol dehydrogenase 79
aspartic acid 79
Silymarin 78
threonine 75
more...