Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:2.6.1.1 (
aspartate aminotransferase
)
21,665
document(s) hit in 31,850,051 MEDLINE articles (0.02 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
aspartate aminotransferase
14774
alanine aminotransferase
7069
AST
6040
alkaline phosphatase
3556
lactate dehydrogenase
2397
albumin
1860
superoxide dismutase
1735
GSH
1560
Sep
1485
catalase
1353
creatine kinase
1262
glutathione peroxidase
1039
TNF
1031
ALP
874
AAT
845
Mol
791
LDH
782
hemoglobin
778
tumor necrosis factor
744
insulin
739
SOD
598
IL-6
596
GGT
509
caspase-3
497
glutamate pyruvate transaminase
462
lipopolysaccharide
461
HDL
454
cytokine
426
glutamate dehydrogenase
420
prothrombin
400
collagen
398
gamma-glutamyltransferase
385
CAT
340
C-reactive protein
324
glutathione reductase
319
serum albumin
306
myeloperoxidase
299
galactosamine
290
amylase
286
inducible nitric oxide synthase
282
gamma-glutamyl transpeptidase
280
interleukin-6
277
Bcl-2
255
interferon
249
malate dehydrogenase
231
glutathione S-transferase
224
IL-10
220
IFN
216
GTG
214
ATP
210
acid phosphatase
198
LPS
181
Alanine aminotransferase
177
antioxidant enzyme
177
Nrf2
172
ferritin
172
gut
166
SMA
163
TLR4
156
cytochrome P450
155
endoplasmic reticulum
152
microsomal
152
lipase
151
fibrinogen
151
heme oxygenase-1
149
ROS
143
CYP2E1
142
p65
140
GST
139
tumor necrosis factor alpha
134
erythroid
132
serum protein
131
p53
130
TNF-alpha
130
FIB
129
transferrin
125
sorbitol dehydrogenase
123
surface antigen
123
acetylcholinesterase
121
She
118
more...
Disease
GSH
1560
liver disease
836
cirrhosis
799
cancer
771
hepatitis
749
ischemia
649
fatty liver
640
liver fibrosis
635
diabetes
631
tumor
593
hepatocellular carcinoma
556
chronic hepatitis
535
hepatitis C
465
hepatitis B
452
obesity
386
cholestasis
302
cold
259
anemia
254
sepsis
238
hypertension
235
thrombocytopenia
232
sepsis
226
alcoholic fatty liver
225
myocardial infarction
206
viral hepatitis
202
type 2 diabetes
201
depression
193
chronic liver disease
190
hyperlipidemia
188
metabolic syndrome
178
Nonalcoholic fatty liver
176
HIV
164
acute hepatitis
155
hyperglycemia
154
liver cancer
146
virus infection
135
acute myocardial infarction
128
alcoholism
124
rash
122
cardiovascular disease
118
carcinoma
117
dyslipidemia
113
Hepatotoxicity
113
breast cancer
108
hypercholesterolemia
106
primary biliary cirrhosis
99
infectious diseases
99
atherosclerosis
97
leukopenia
97
alcohol abuse
97
pneumonia
96
neutropenia
94
liver cancer
92
pruritus
92
hypoglycemia
91
immunodeficiency
87
renal failure
87
hyperbilirubinemia
87
myopathy
85
tuberculosis
85
hepatitis A
85
carcinogenesis
84
renal disease
81
proteinuria
81
chronic active hepatitis
81
myocardial ischemia
79
dehydration
78
AAT deficiency
75
viremia
75
malnutrition
72
portal hypertension
71
encephalopathy
71
stroke
69
tumor growth
69
iron overload
69
dengue
68
lymphoma
68
heart failure
66
rheumatoid arthritis
66
cholangitis
66
more...
Symptom
diarrhea
267
fatigue
209
pain
183
anorexia
170
vomiting
167
hepatomegaly
162
nausea
160
anesthesia
148
abdominal pain
139
weakness
101
splenomegaly
82
overweight
81
headache
73
myalgia
73
lethargy
71
cough
69
dyspnea
66
seizures
61
hypothermia
48
nausea and vomiting
40
starvation
40
erythema
39
Ill
36
chest pain
35
hepatosplenomegaly
35
arthralgia
33
respiratory distress
33
chills
33
ataxia
31
collapse
29
exhaustion
28
hypoproteinemia
25
constipation
25
flushing
24
asthenia
23
angina
20
emaciation
19
epigastric pain
19
polyuria
18
decreased appetite
18
oliguria
17
tremor
16
analgesia
15
polydipsia
15
dizziness
15
discomfort
14
discomfort
14
insomnia
14
incoordination
14
sleepiness
13
right upper quadrant pain
12
colic
12
paresis
11
acute stress
11
shortness of breath
11
back pain
11
sore throat
11
functional recovery
11
abdominal discomfort
10
agitation
10
acidity
10
nasal discharge
9
pallor
9
tachypnea
9
cyanosis
9
cachexia
9
regurgitation
9
hypotonia
9
dark urine
8
apathy
8
skin irritation
8
hyperoxia
8
thinning
6
frequent urination
6
fever of unknown origin
6
exertional dyspnea
6
hypercapnia
5
night sweats
5
bone pain
5
bloating
5
more...
Drug
vitamin E
240
ascorbate
202
pyridoxal phosphate
171
ROS
143
lysine
126
Ethanol
94
NADH
90
IL-2
83
Asn
66
Monit
65
Cardiovasc
60
Albumin
58
ROC
49
Glutathione
48
IFN-gamma
45
Alanine
44
Vitamin E
43
CTX
41
TAC
40
CSF
40
Portal
38
Vitamin B
35
ALA
35
caffeine
35
Dermatol
33
ACT
33
TAT
30
citric acid
29
Serum albumin
28
Bifidobacterium
28
MAP
27
Leaf
25
niacin
23
AGG
23
CTC
22
lactose
22
Nephron
22
Nephron
22
Dial
21
CTC
21
TTC
20
CTX
19
Heme
19
CTX
19
ZnO
18
Glycyrrhiza
18
CCL
18
Fructose
16
Gel
15
ampicillin
15
ENT
15
EE2
15
CTT
15
NH3
15
Ginseng
14
Isoniazid
13
Rutin
13
Pyridoxal
13
Acacia
13
Tacrolimus
13
Ringer's solution
12
Monensin
12
NAG
11
TiO2
11
Aloe
11
L-tyrosine
10
Simvastatin
10
Pyridoxal phosphate
10
Norplant
9
CTA
9
Rosiglitazone
9
PCB
9
TAK
9
Isotretinoin
9
Biopolymers
9
Prednisolone
9
Emodin
8
Emodin
8
Fraction
8
Adriamycin
8
more...
Enzyme
aspartate aminotransferase
21665
alanine aminotransferase
13093
AST
6039
alkaline phosphatase
3559
lactate dehydrogenase
2637
superoxide dismutase
2253
catalase
1658
creatine kinase
1617
gamma-glutamyl transpeptidase
1479
glutathione peroxidase
1054
glutamate dehydrogenase
443
glutamate dehydrogenase
440
glutamate dehydrogenase
438
peroxidase
379
caspase-3
374
glutathione S-transferase
366
glutathione reductase
320
malate dehydrogenase
294
acetylcholinesterase
277
mitogen-activated protein kinase
268
cholinesterase
205
acid phosphatase
198
lipase
160
glucose-6-phosphate dehydrogenase
140
ERK
131
AMP-activated protein kinase
128
sorbitol dehydrogenase
124
ATPase
120
isocitrate dehydrogenase
120
glutamine synthetase
116
protein kinase
108
isocitrate dehydrogenase
107
thromboplastin
107
lysozyme
104
phosphoenolpyruvate carboxykinase
98
phosphoenolpyruvate carboxykinase
98
aldolase
98
phosphoenolpyruvate carboxykinase
96
alcohol dehydrogenase
80
citrate synthase
79
pyruvate kinase
78
hexokinase
75
AMPK
74
glucose-6-phosphatase
73
focal adhesion kinase
72
AMPK
71
glutaminase
70
xanthine oxidase
68
succinate dehydrogenase
68
collagenase
65
trypsin
63
NQO1
62
ceruloplasmin
61
tyrosine aminotransferase
59
caspase-9
58
transpeptidase
56
arginase
53
luciferase
52
reverse transcriptase
49
acetyl-CoA carboxylase
48
MDH
45
MDH
45
AGT
43
aldehyde dehydrogenase
43
heme oxygenase
42
phosphoglucose isomerase
41
demethylase
41
alpha-amylase
40
neutrophil elastase
39
6-phosphogluconate dehydrogenase
38
6-phosphogluconate dehydrogenase
38
pyruvate carboxylase
38
CYP3A4
36
phosphoenolpyruvate carboxylase
36
PARP
35
leucine aminopeptidase
35
alpha-ketoglutarate dehydrogenase
35
CPT
35
beta-glucuronidase
35
cytochrome oxidase
35
more...
Compound
glucose
2464
creatinine
2388
urea
2191
GSH
1597
GSH
1597
Clin
1488
Dec
1481
water
1181
nitrogen
1062
TNF
1031
DNA
989
alanine
881
Pac
874
ALP
874
oxygen
852
sodium
844
AAT
841
calcium
797
ethanol
769
phosphate
642
MDA
562
potassium
558
CCl4
553
glutamate
538
nitric oxide
486
iron
396
phosphorus
394
CAT
348
CAT
340
CAT
340
APAP
308
ammonia
294
2-oxoglutarate
275
acetate
257
zinc
242
cysteine
234
copper
228
methionine
220
hydrogen
219
ATP
210
sulfate
198
arginine
198
glutamine
197
lysine
182
selenium
179
cadmium
168
galactose
162
tyrosine
146
Asp
144
His
143
leucine
142
methanol
140
hyaluronic acid
133
N-acetylcysteine
129
Phe
128
salt
122
nitrate
120
NAD
118
GPT
111
CO2
108
serine
107
ammonium
101
GSSG
100
NAD
97
DPPH
94
NADH
90
Lactate
86
MTT
85
tryptophan
84
PEG
83
tryptophan
82
NH2
82
ethyl acetate
81
tryptophan
80
tryptophan
80
NADP
79
alcohol dehydrogenase
79
aspartic acid
79
Silymarin
78
threonine
75
more...