Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:2.6.1.1 (
aspartate aminotransferase
)
21,665
document(s) hit in 31,850,051 MEDLINE articles (0.02 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
aspartate aminotransferase
14774
alanine aminotransferase
7069
AST
6040
alkaline phosphatase
3556
lactate dehydrogenase
2397
albumin
1860
superoxide dismutase
1735
GSH
1560
Sep
1485
catalase
1353
creatine kinase
1262
glutathione peroxidase
1039
TNF
1031
ALP
874
AAT
845
Mol
791
LDH
782
hemoglobin
778
tumor necrosis factor
744
insulin
739
SOD
598
IL-6
596
GGT
509
caspase-3
497
glutamate pyruvate transaminase
462
lipopolysaccharide
461
HDL
454
cytokine
426
glutamate dehydrogenase
420
prothrombin
400
collagen
398
gamma-glutamyltransferase
385
CAT
340
C-reactive protein
324
glutathione reductase
319
serum albumin
306
myeloperoxidase
299
galactosamine
290
amylase
286
inducible nitric oxide synthase
282
gamma-glutamyl transpeptidase
280
interleukin-6
277
Bcl-2
255
interferon
249
malate dehydrogenase
231
glutathione S-transferase
224
IL-10
220
IFN
216
GTG
214
ATP
210
acid phosphatase
198
LPS
181
Alanine aminotransferase
177
antioxidant enzyme
177
Nrf2
172
ferritin
172
gut
166
SMA
163
TLR4
156
cytochrome P450
155
endoplasmic reticulum
152
microsomal
152
fibrinogen
151
lipase
151
heme oxygenase-1
149
ROS
143
CYP2E1
142
p65
140
GST
139
tumor necrosis factor alpha
134
erythroid
132
serum protein
131
p53
130
TNF-alpha
130
FIB
129
transferrin
125
sorbitol dehydrogenase
123
surface antigen
123
acetylcholinesterase
121
She
118
HO-1
115
smooth muscle actin
113
glutamine synthetase
113
NMR
113
CD4
111
Aspartate aminotransferase
111
CRP
111
GPT
111
myoglobin
109
thromboplastin
108
glucose-6-phosphate dehydrogenase
107
isocitrate dehydrogenase
104
adiponectin
104
lysozyme
103
JNK
102
p38
100
ATPase
98
NAD
97
COX-2
94
cytochrome
93
leptin
93
NADH
92
CPK
92
proliferating cell nuclear antigen
91
PPAR
91
Pol
88
alpha-fetoprotein
85
peroxisome proliferator-activated receptor
85
cyclooxygenase-2
84
gamma-glutamyltranspeptidase
84
MAPK
84
IL-2
82
thymus
81
peroxidase
80
TAT
80
carp
80
IL-8
79
caspase-9
78
cytochrome P450 2E1
78
cytochrome P-450
78
pyruvate kinase
77
reductase
76
Alkaline phosphatase
76
fatty acid synthase
76
IL-4
76
ALB
75
citrate synthase
75
hexokinase
75
HSP70
73
AFP
73
haptoglobin
72
glucose-6-phosphatase
72
AMPK
71
cytochrome c
71
nitric oxide synthase
69
PI3K
68
IL-1
68
glutaminase
68
mTOR
68
xanthine oxidase
67
MCP-1
66
phosphatase
66
CD8
66
phosphoenolpyruvate carboxykinase
66
kit
66
Gen
66
AMP-activated protein kinase
65
A-I
65
alcohol dehydrogenase
65
polypeptide
64
interleukin 6
64
metallothionein
62
glycoprotein
60
ceruloplasmin
60
NADPH
60
NADP
59
Albumin
58
lymphoid
57
ERK
56
IgA
56
more...
Disease
GSH
1560
liver disease
836
cirrhosis
799
cancer
771
hepatitis
749
ischemia
649
fatty liver
640
liver fibrosis
635
diabetes
631
tumor
593
hepatocellular carcinoma
556
chronic hepatitis
535
hepatitis C
465
hepatitis B
452
obesity
386
cholestasis
302
cold
259
anemia
254
sepsis
238
hypertension
235
thrombocytopenia
232
sepsis
226
alcoholic fatty liver
225
myocardial infarction
206
viral hepatitis
202
type 2 diabetes
201
depression
193
chronic liver disease
190
hyperlipidemia
188
metabolic syndrome
178
Nonalcoholic fatty liver
176
HIV
164
acute hepatitis
155
hyperglycemia
154
liver cancer
146
virus infection
135
acute myocardial infarction
128
alcoholism
124
rash
122
cardiovascular disease
118
carcinoma
117
dyslipidemia
113
Hepatotoxicity
113
breast cancer
108
hypercholesterolemia
106
primary biliary cirrhosis
99
infectious diseases
99
atherosclerosis
97
alcohol abuse
97
leukopenia
97
pneumonia
96
neutropenia
94
pruritus
92
liver cancer
92
hypoglycemia
91
hyperbilirubinemia
87
immunodeficiency
87
renal failure
87
hepatitis A
85
tuberculosis
85
myopathy
85
carcinogenesis
84
proteinuria
81
chronic active hepatitis
81
renal disease
81
myocardial ischemia
79
dehydration
78
AAT deficiency
75
viremia
75
malnutrition
72
portal hypertension
71
encephalopathy
71
stroke
69
tumor growth
69
iron overload
69
lymphoma
68
dengue
68
heart failure
66
cholangitis
66
rheumatoid arthritis
66
hepatic encephalopathy
65
emphysema
65
acute pancreatitis
64
AIDS
64
chronic renal failure
59
alcoholic hepatitis
58
cytomegalovirus
57
gallstones
57
acute renal failure
56
coagulopathy
56
West
56
adenocarcinoma
55
pancreatitis
55
malaria
53
metastases
53
B-cell lymphoma
53
lymphopenia
52
plaque
51
Acute liver failure
51
SEM
51
schistosomiasis
50
influenza
50
arthritis
50
eosinophilia
49
sickle cell disease
48
Infection
47
preeclampsia
47
cardiomyopathy
47
Hepatocellular carcinoma
46
thalassemia
45
HCC
45
glucose intolerance
43
asthma
43
lymphadenopathy
43
alcoholic cirrhosis
43
coma
43
chronic obstructive pulmonary disease
42
lung cancer
42
primary sclerosing cholangitis
42
leukemia
42
ASAT
42
hypothyroidism
42
periodontitis
41
fits
41
ACP
41
Cirrhosis
39
disseminated intravascular coagulation
38
epilepsy
38
biliary obstruction
37
abdominal aortic aneurysm
37
prostate cancer
36
SDS
36
Alcoholic liver disease
36
Epstein
36
obstructive jaundice
35
heart disease
34
hyperinsulinemia
34
Evans
34
peritonitis
34
uterus
34
ash
34
FAS
34
worms
34
hyperthyroidism
34
metabolic disorder
33
Alzheimer's disease
33
SARS
33
leishmaniasis
32
ketosis
32
coronary artery disease
32
systemic lupus erythematosus
32
graft-versus-host disease
32
liver metastases
31
AAA
31
Hodgkin's disease
31
melanoma
31
Klebsiella
30
Kawasaki disease
30
acute myeloid leukemia
30
Wilson's disease
30
more...
Symptom
diarrhea
267
fatigue
209
pain
183
anorexia
170
vomiting
167
hepatomegaly
162
nausea
160
anesthesia
148
abdominal pain
139
weakness
101
splenomegaly
82
overweight
81
headache
73
myalgia
73
lethargy
71
cough
69
dyspnea
66
seizures
61
hypothermia
48
starvation
40
nausea and vomiting
40
erythema
39
Ill
36
hepatosplenomegaly
35
chest pain
35
respiratory distress
33
arthralgia
33
chills
33
ataxia
31
collapse
29
exhaustion
28
constipation
25
hypoproteinemia
25
flushing
24
asthenia
23
angina
20
epigastric pain
19
emaciation
19
polyuria
18
decreased appetite
18
oliguria
17
tremor
16
analgesia
15
dizziness
15
polydipsia
15
incoordination
14
discomfort
14
insomnia
14
discomfort
14
sleepiness
13
right upper quadrant pain
12
colic
12
back pain
11
paresis
11
sore throat
11
acute stress
11
shortness of breath
11
functional recovery
11
agitation
10
acidity
10
abdominal discomfort
10
regurgitation
9
hypotonia
9
pallor
9
cachexia
9
cyanosis
9
tachypnea
9
nasal discharge
9
dark urine
8
apathy
8
skin irritation
8
hyperoxia
8
frequent urination
6
fever of unknown origin
6
exertional dyspnea
6
thinning
6
lassitude
5
ketonuria
5
bloating
5
hypercapnia
5
rigors
5
muscle rigidity
5
night sweats
5
bone pain
5
acute abdomen
4
abdominal cramps
4
blurred vision
4
low back pain
4
muscle cramps
4
muscle stiffness
4
consciousness disturbance
4
periorbital edema
4
jaundice of the skin
4
acute pain
4
vertigo
3
hyperemesis gravidarum
3
intestinal bleeding
3
stomach pain
3
dysarthria
3
Decreased activity
3
clubbing
3
stigma
3
dystonia
3
dysuria
3
prostration
3
HSA
3
No adverse effect
3
leg pain
3
nasal congestion
3
despair
3
flank pain
3
Wind
3
rales
3
rhinorrhea
3
memory loss
3
menopausal symptoms
3
hemoptysis
3
bradypnea
3
acute abdominal pain
3
excessive sweating
3
hunger
2
wheezing
2
non-productive cough
2
hyperesthesia
2
hypocapnia
2
Muscle soreness
2
adenitis
2
urinary frequency
2
meningism
2
livedo
2
hypertonia
2
Spots
2
asterixis
2
myoclonus
2
numbness
2
knee pain
2
tonic-clonic seizure
2
twitching
2
dry skin
2
Tenderness
2
Murphy's sign
2
generalized rash
2
spasm
2
hangover
2
cerebellar ataxia
2
hoarseness
2
hot flashes
1
POA
1
Limb weakness
1
Psychiatric symptoms
1
DNA marker
1
tense
1
cancer pain
1
Fluctuation
1
Flu-like symptoms
1
feeling sick
1
drooling
1
orthopnea
1
nocturnal cough
1
hot flushes
1
more...
Drug
vitamin E
240
ascorbate
202
pyridoxal phosphate
171
ROS
143
lysine
126
Ethanol
94
NADH
90
IL-2
83
Asn
66
Monit
65
Cardiovasc
60
Albumin
58
ROC
49
Glutathione
48
IFN-gamma
45
Alanine
44
Vitamin E
43
CTX
41
CSF
40
TAC
40
Portal
38
caffeine
35
Vitamin B
35
ALA
35
Dermatol
33
ACT
33
TAT
30
citric acid
29
Bifidobacterium
28
Serum albumin
28
MAP
27
Leaf
25
niacin
23
AGG
23
lactose
22
CTC
22
Nephron
22
Nephron
22
Dial
21
CTC
21
TTC
20
CTX
19
CTX
19
Heme
19
ZnO
18
Glycyrrhiza
18
CCL
18
Fructose
16
EE2
15
NH3
15
CTT
15
Gel
15
ENT
15
ampicillin
15
Ginseng
14
Tacrolimus
13
Acacia
13
Pyridoxal
13
Isoniazid
13
Rutin
13
Monensin
12
Ringer's solution
12
NAG
11
TiO2
11
Aloe
11
Simvastatin
10
Pyridoxal phosphate
10
L-tyrosine
10
Norplant
9
PCB
9
Prednisolone
9
Biopolymers
9
Rosiglitazone
9
CTA
9
TAK
9
Isotretinoin
9
Emodin
8
Adriamycin
8
Vitamin A
8
Retinoic acid
8
Emodin
8
Fraction
8
Spectrum
7
Swertia
7
Fluorescein
7
Mutagen
7
EPA
7
Infliximab
7
ABC
7
Infliximab
7
ATV
7
DMI
7
AZT
7
OTC
7
Captopril
7
Olive oil
7
MOF
7
Nitric Oxide
6
Doxycycline
6
NAH
6
Asthma
6
Kenyan
6
FAD
6
ETA
6
G-CSF
6
Sorafenib
5
Fluconazole
5
Lovastatin
5
Histamine
5
Entecavir
5
Arsenic trioxide
5
Entecavir
5
Liraglutide
5
Sodium valproate
5
Capsicum
5
CoCl2
5
CoCl2
5
RFP
5
Bosentan
5
DNase I
5
Lead acetate
5
NBT
5
Bosentan
5
Honey
5
Pravastatin
5
Sesame oil
5
HCH
4
TMS
4
Swainsonine
4
Iohexol
4
Furan
4
DPA
4
Artesunate
4
ZnCl2
4
Clofibrate
4
Itraconazole
4
Indocyanine green
4
Ranitidine
4
Caspofungin
4
Senna
4
Trimethoprim-sulfamethoxazole
4
ZnCl2
4
Fipronil
4
Senna
4
MgSO4
4
DM1
4
Tiopronin
4
MRC
4
Propofol
4
CAM
4
Ketoconazole
4
ADR
4
PMEA
4
PTH
4
Sesamol
4
Prednisone
4
Moxifloxacin
4
Gemfibrozil
4
Gastro
4
uPA
4
more...
Enzyme
aspartate aminotransferase
21665
alanine aminotransferase
13093
AST
6039
alkaline phosphatase
3559
lactate dehydrogenase
2637
superoxide dismutase
2253
catalase
1658
creatine kinase
1617
gamma-glutamyl transpeptidase
1479
glutathione peroxidase
1054
glutamate dehydrogenase
443
glutamate dehydrogenase
440
glutamate dehydrogenase
438
peroxidase
379
caspase-3
374
glutathione S-transferase
366
glutathione reductase
320
malate dehydrogenase
294
acetylcholinesterase
277
mitogen-activated protein kinase
268
cholinesterase
205
acid phosphatase
198
lipase
160
glucose-6-phosphate dehydrogenase
140
ERK
131
AMP-activated protein kinase
128
sorbitol dehydrogenase
124
ATPase
120
isocitrate dehydrogenase
120
glutamine synthetase
116
protein kinase
108
isocitrate dehydrogenase
107
thromboplastin
107
lysozyme
104
aldolase
98
phosphoenolpyruvate carboxykinase
98
phosphoenolpyruvate carboxykinase
98
phosphoenolpyruvate carboxykinase
96
alcohol dehydrogenase
80
citrate synthase
79
pyruvate kinase
78
hexokinase
75
AMPK
74
glucose-6-phosphatase
73
focal adhesion kinase
72
AMPK
71
glutaminase
70
xanthine oxidase
68
succinate dehydrogenase
68
collagenase
65
trypsin
63
NQO1
62
ceruloplasmin
61
tyrosine aminotransferase
59
caspase-9
58
transpeptidase
56
arginase
53
luciferase
52
reverse transcriptase
49
acetyl-CoA carboxylase
48
MDH
45
MDH
45
aldehyde dehydrogenase
43
AGT
43
heme oxygenase
42
demethylase
41
phosphoglucose isomerase
41
alpha-amylase
40
neutrophil elastase
39
pyruvate carboxylase
38
6-phosphogluconate dehydrogenase
38
6-phosphogluconate dehydrogenase
38
CYP3A4
36
phosphoenolpyruvate carboxylase
36
cytochrome oxidase
35
CPT
35
leucine aminopeptidase
35
alpha-ketoglutarate dehydrogenase
35
PARP
35
beta-glucuronidase
35
pyruvate dehydrogenase
34
phosphoglucomutase
34
NO synthase
34
thrombin
34
fumarase
32
delta-aminolevulinic acid dehydratase
32
aldehyde dehydrogenase
31
glutamate decarboxylase
31
ACE
31
phosphofructokinase
31
5'-nucleotidase
31
elastase
31
ornithine transcarbamylase
31
TAT
30
lactic acid dehydrogenase
29
gamma-glutamylcysteine synthetase
29
caspase-8
28
complex I
28
caspase-1
28
lipoprotein lipase
28
aldehyde dehydrogenase
28
glutamate synthase
28
aldehyde dehydrogenase
28
aromatic amino acid aminotransferase
28
NOS
28
aldehyde dehydrogenase
28
adenosine deaminase
27
glutamic dehydrogenase
27
ornithine aminotransferase
26
glucokinase
26
phosphorylase
25
glyceraldehyde-3-phosphate dehydrogenase
25
glutamate synthase
25
diaphorase
25
MIP
25
ECH
24
pyruvate dehydrogenase
24
GABA transaminase
24
pyruvate dehydrogenase
24
GSK
24
glutamate synthase
23
ACS
23
UDP-glucuronosyltransferase
23
CPR
23
adenosine deaminase
23
phospholipase A2
22
thymidine kinase
22
transketolase
22
aconitase
22
PGM
22
beta-galactosidase
21
renin
21
protein kinase C
21
NADPH oxidase
21
CGT
20
glyceraldehyde-3-phosphate dehydrogenase
20
monoamine oxidase
20
RNA polymerase
20
carboxylesterase
20
CYP7A1
19
APC
19
hexosaminidase
19
asparagine synthetase
19
NADPH oxidase
19
CPT
19
CPT
19
type III procollagen
19
glyceraldehyde-3-phosphate dehydrogenase
19
paraoxonase
18
enolase
17
fructose 1,6-bisphosphatase
17
RNase
16
ADH
16
MAP
16
transcriptase
16
adenylate kinase
16
branched-chain aminotransferase
16
chymotrypsin
15
DNA polymerase
15
ornithine decarboxylase
15
more...
Compound
glucose
2464
creatinine
2388
urea
2191
GSH
1597
GSH
1597
Clin
1488
Dec
1481
water
1181
nitrogen
1062
TNF
1031
DNA
989
alanine
881
ALP
874
Pac
874
oxygen
852
sodium
844
AAT
841
calcium
797
ethanol
769
phosphate
642
MDA
562
potassium
558
CCl4
553
glutamate
538
nitric oxide
486
iron
396
phosphorus
394
CAT
348
CAT
340
CAT
340
APAP
308
ammonia
294
2-oxoglutarate
275
acetate
257
zinc
242
cysteine
234
copper
228
methionine
220
hydrogen
219
ATP
210
arginine
198
sulfate
198
glutamine
197
lysine
182
selenium
179
cadmium
168
galactose
162
tyrosine
146
Asp
144
His
143
leucine
142
methanol
140
hyaluronic acid
133
N-acetylcysteine
129
Phe
128
salt
122
nitrate
120
NAD
118
GPT
111
CO2
108
serine
107
ammonium
101
GSSG
100
NAD
97
DPPH
94
NADH
90
Lactate
86
MTT
85
tryptophan
84
PEG
83
NH2
82
tryptophan
82
ethyl acetate
81
tryptophan
80
tryptophan
80
NADP
79
alcohol dehydrogenase
79
aspartic acid
79
Silymarin
78
threonine
75
GTP
74
alloxan
73
aflatoxin B1
72
silver
71
aldehyde
70
Glutamate
69
dUTP
66
mercury
65
gallic acid
65
Insulin
65
Curcumin
65
asparagine
65
8-OHdG
63
H2O2
60
ornithine
60
nicotinamide
60
ornithine
60
ornithine
60
ornithine
60
ornithine
60
NADPH
60
NADPH
60
chloroform
59
homocysteine
58
CoA
58
Bilirubin
57
glutamic acid
57
TCA
57
manganese
57
TEM
56
Ile
56
Malondialdehyde
56
aniline
55
oxalacetate
55
ADP
54
Cholesterol
53
Hematoxylin
52
Adriamycin
51
Gly
50
PLP
50
vitamin D
50
Cardiol
50
ADP
49
ADP
49
valine
48
phenol
48
TAA
48
STZ
48
GABA
47
ADR
47
proline
47
GABA
47
Vitamin E
47
chromium
46
glycerol
45
Quercetin
45
INH
45
Hemoglobin
44
DMSO
44
DDP
44
Alanine
43
AMP
43
PEG
43
MCH
42
bromide
42
aspartic acid
42
acetic acid
41
CTX
41
acetaldehyde
40
iodine
40
isoleucine
40
isoleucine
40
pyridine
40
Lead
39
Arsenic
39
SDS
38
hexane
38
Melatonin
38
DEN
38
cobalt
37
more...