Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:2.5.1.61 (porphobilinogen deaminase)
637 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
porphobilinogen deaminase 439
hydroxymethylbilane synthase 137
PBG 87
erythroid 78
Mol 70
ferrochelatase 52
Sep 43
PCT 40
housekeeping 33
UPS 32
uroporphyrinogen III synthase 30
delta-aminolevulinic acid dehydratase 28
ALA 28
hemoglobin 20
protoporphyrinogen oxidase 20
HMBS 19
porphobilinogen synthase 19
NF-E2 16
coproporphyrinogen oxidase 15
beta-globin 14
variegate porphyria 13
polypeptide 13
glyceraldehyde-3-phosphate dehydrogenase 13
GATA-1 13
delta-aminolevulinate synthase 13
catalase 11
erythropoietin 10
gamma-globin 10
heme oxygenase-1 9
cytochrome P450 9
Gen 9
microsomal 8
transferrin receptor 7
beta-2-microglobulin 7
cytochrome P-450 7
tyrosinase 6
erythropoietin receptor 6
reductase 6
endoplasmic reticulum 6
ferritin 6
cyclophilin A 6
superoxide dismutase 6
fused 6
axonal 5
tRNA 5
AIP 5
HPRT 5
cytochrome 5
beta-actin 5
MRI 5
ALAS1 5
B2M 4
NF-E1 4
methyltransferase 4
hypoxanthine-guanine phosphoribosyltransferase 4
B12 4
proteasome 4
ubiquitin C 4
cryptic 4
Ferrochelatase 4
glutathione reductase 4
Uroporphyrinogen decarboxylase 4
cytokine 4
NAD 4
NMR 4
ATP 3
tumor necrosis factor 3
transferrin 3
ACTB 3
interferon 3
beta-2 microglobulin 3
glycophorin B 3
GATA1 3
AP1 3
transcriptional activator 3
MEL 3
P450 3
ribosomal protein 3
p45 NF-E2 3
NADPH 3
more...
Disease
acute intermittent porphyria 247
porphyria 83
cancer 37
tumor 22
hepatic porphyria 17
anemia 17
variegate porphyria 16
neuropathy 16
porphyria cutanea tarda 15
hepatocellular carcinoma 10
CEP 10
erythroleukemia 10
coproporphyria 10
enzyme deficiency 9
schizophrenia 9
leukemia 9
depression 8
AIP 8
peripheral neuropathy 8
adenocarcinoma 8
hypertension 7
encephalopathy 6
liver disease 6
melanoma 6
photosensitivity 6
renal failure 5
AIP 5
psychosis 5
metabolic disorder 5
carcinoma 5
genetic disorder 4
breast cancer 4
tumorigenesis 4
diabetes 4
uremia 4
lymphoma 4
erythropoietic protoporphyria 4
tetraplegia 3
chronic myeloid leukemia 3
malnutrition 3
renal disease 3
chronic renal failure 3
polyneuropathy 3
hemolytic anemia 3
minimal residual disease 3
respiratory failure 3
glioblastoma 3
Barrett's esophagus 3
Leukemia 3
cirrhosis 3
mammary tumor 2
infectious diseases 2
hyperbilirubinemia 2
coma 2
pheochromocytoma 2
malaria 2
epilepsy 2
trisomy 2
MCF 2
Melanoma 2
DBA 2
dehydration 2
Friend leukemia 2
colorectal cancer 2
acute myeloid leukemia 2
Dubin-Johnson syndrome 2
psychiatric diagnosis 2
Epstein 2
fits 2
mesothelioma 2
delirium 2
iron deficiency 2
bladder cancer 2
West 2
Pineal 2
glioma 2
neuroblastoma 2
Posterior 2
Hereditary coproporphyria 2
mental illness 2
more...
Symptom
abdominal pain 30
seizures 8
vomiting 8
pain 7
weakness 5
starvation 4
constipation 4
anesthesia 4
nausea 4
acute abdominal pain 3
acute abdomen 2
agitation 2
headache 2
arthralgia 1
sleepiness 1
ataxia 1
stomach pain 1
fever of unknown origin 1
Physical findings 1
acidity 1
astasia 1
hepatosplenomegaly 1
HSA 1
paresis 1
erythema 1
paresthesia 1
myalgia 1
chills 1
colic 1
generalized abdominal pain 1
Drug
ALA 34
Heme 15
lysine 4
Leaf 3
Dermatol 3
VCR 2
DNase I 2
NADH 1
IFN-gamma 1
IL-2 1
Pyridoxal 1
Vitamin B 1
ascorbate 1
Alanine 1
Paraffin 1
MAP 1
CSF 1
ROS 1
Ethanol 1
NH3 1
Doxycycline 1
Capsicum 1
AMC 1
THF 1
Arsenic trioxide 1
IFN-beta 1
Enzyme
porphobilinogen deaminase 637
ALA synthase 58
ferrochelatase 52
delta-aminolevulinic acid dehydratase 49
uroporphyrinogen decarboxylase 43
protoporphyrinogen oxidase 21
coproporphyrinogen oxidase 20
deaminase 18
glyceraldehyde-3-phosphate dehydrogenase 14
glyceraldehyde-3-phosphate dehydrogenase 13
glyceraldehyde-3-phosphate dehydrogenase 13
glyceraldehyde-3-phosphate dehydrogenase 13
glyceraldehyde-3-phosphate dehydrogenase 13
porphobilinogenase 12
catalase 11
heme oxygenase 9
glutamyl-tRNA reductase 7
luciferase 6
hypoxanthine-guanine phosphoribosyltransferase 6
reverse transcriptase 6
superoxide dismutase 6
tyrosinase 6
succinate dehydrogenase 5
coproporphyrinogen III oxidase 5
Mg-chelatase 4
RNA polymerase 4
proteasome 4
glutathione reductase 4
chlorophyllase 3
transcriptase 3
lactate dehydrogenase 3
focal adhesion kinase 3
ERK 2
cystathionine beta-synthase 2
alanine aminotransferase 2
endonuclease 2
demethylase 2
glucose-6-phosphate dehydrogenase 2
protochlorophyllide oxidoreductase 2
ATP synthase 2
peroxidase 2
collagenase 2
DNase 2
ECH 1
TMT 1
tryptophan synthase 1
cysteine synthase 1
MCS 1
phosphoglycerate kinase 1
GLO 1
NADPH oxidase 1
glutamate dehydrogenase 1
glutamate dehydrogenase 1
phosphoglyceromutase 1
RNase 1
protein kinase 1
SPC 1
SirB 1
AMPK 1
glutamate-1-semialdehyde aminotransferase 1
firefly luciferase 1
CysG 1
cystathionine gamma-synthase 1
nicotinamidase 1
glutamate formiminotransferase 1
ribonucleotide reductase 1
L-serine dehydratase 1
enoyl-ACP reductase 1
DNA methyltransferase 1
ribonucleotide reductase 1
NADPH oxidase 1
rhodanese 1
pepsin 1
L-serine hydro-lyase 1
beta-glucuronidase 1
MMP-3 1
cobaltochelatase 1
carbonic anhydrase 1
RNase 1
transglutaminase 1
more...
Compound
DNA 83
Clin 71
delta-aminolevulinic acid 52
Dec 46
iron 24
PBG 19
cysteine 17
oxygen 17
Heme 16
sodium 16
zinc 16
hydroxymethylbilane 15
HIS 14
water 12
phosphate 11
coproporphyrinogen III 10
uroporphyrin I 9
glutamate 9
glucose 9
methionine 8
His 8
butyric acid 7
acetate 7
sulfate 7
arginine 7
phenol 6
butyric acid 5
butyric acid 5
DEAE 5
nitrogen 5
Protoporphyrin IX 5
lysine 5
ammonium 5
benzene 5
Luminal 5
NH2 5
DMSO 5
hydroquinone 5
Chlorophyll 5
Asp 4
Uroporphyrinogen III 4
salt 4
alanine 4
Lead 4
NAD 4
leucine 4
NAD 4
TBP 3
HCl 3
hydrogen 3
tryptophan 3
galactose 3
Porphyrin 3
NADPH 3
Ile 3
CoA 3
tryptophan 3
Benzene 3
Gly 3
EDTA 3
glutamine 3
TBP 3
serine 3
proline 3
MTT 3
ethanol 3
1,2,4-benzenetriol 3
EDTA 3
isoleucine 3
NADPH 3
tryptophan 3
silver 3
isoleucine 3
tryptophan 3
PDT 3
aniline 3
Porphyrin 3
ATP 3
copper 2
urea 2
more...