Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:2.5.1.61 (
porphobilinogen deaminase
)
637
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
porphobilinogen deaminase
439
hydroxymethylbilane synthase
137
PBG
87
erythroid
78
Mol
70
ferrochelatase
52
Sep
43
PCT
40
housekeeping
33
UPS
32
uroporphyrinogen III synthase
30
ALA
28
delta-aminolevulinic acid dehydratase
28
hemoglobin
20
protoporphyrinogen oxidase
20
HMBS
19
porphobilinogen synthase
19
NF-E2
16
coproporphyrinogen oxidase
15
beta-globin
14
variegate porphyria
13
polypeptide
13
glyceraldehyde-3-phosphate dehydrogenase
13
GATA-1
13
delta-aminolevulinate synthase
13
catalase
11
gamma-globin
10
erythropoietin
10
Gen
9
heme oxygenase-1
9
cytochrome P450
9
microsomal
8
beta-2-microglobulin
7
cytochrome P-450
7
transferrin receptor
7
erythropoietin receptor
6
tyrosinase
6
endoplasmic reticulum
6
reductase
6
fused
6
more...
Disease
acute intermittent porphyria
247
porphyria
83
cancer
37
tumor
22
hepatic porphyria
17
anemia
17
variegate porphyria
16
neuropathy
16
porphyria cutanea tarda
15
coproporphyria
10
CEP
10
hepatocellular carcinoma
10
erythroleukemia
10
schizophrenia
9
enzyme deficiency
9
leukemia
9
AIP
8
adenocarcinoma
8
depression
8
peripheral neuropathy
8
hypertension
7
liver disease
6
encephalopathy
6
photosensitivity
6
melanoma
6
renal failure
5
carcinoma
5
psychosis
5
metabolic disorder
5
AIP
5
uremia
4
diabetes
4
erythropoietic protoporphyria
4
breast cancer
4
genetic disorder
4
tumorigenesis
4
lymphoma
4
respiratory failure
3
malnutrition
3
minimal residual disease
3
more...
Symptom
abdominal pain
30
seizures
8
vomiting
8
pain
7
weakness
5
starvation
4
constipation
4
anesthesia
4
nausea
4
acute abdominal pain
3
acute abdomen
2
agitation
2
headache
2
arthralgia
1
sleepiness
1
ataxia
1
stomach pain
1
fever of unknown origin
1
Physical findings
1
acidity
1
astasia
1
hepatosplenomegaly
1
HSA
1
paresis
1
erythema
1
paresthesia
1
myalgia
1
chills
1
colic
1
generalized abdominal pain
1
Drug
ALA
34
Heme
15
lysine
4
Leaf
3
Dermatol
3
VCR
2
DNase I
2
NADH
1
IFN-gamma
1
IL-2
1
Pyridoxal
1
Vitamin B
1
ascorbate
1
Alanine
1
Paraffin
1
MAP
1
CSF
1
ROS
1
Ethanol
1
NH3
1
Doxycycline
1
Capsicum
1
AMC
1
THF
1
Arsenic trioxide
1
IFN-beta
1
Enzyme
porphobilinogen deaminase
637
ALA synthase
58
ferrochelatase
52
delta-aminolevulinic acid dehydratase
49
uroporphyrinogen decarboxylase
43
protoporphyrinogen oxidase
21
coproporphyrinogen oxidase
20
deaminase
18
glyceraldehyde-3-phosphate dehydrogenase
14
glyceraldehyde-3-phosphate dehydrogenase
13
glyceraldehyde-3-phosphate dehydrogenase
13
glyceraldehyde-3-phosphate dehydrogenase
13
glyceraldehyde-3-phosphate dehydrogenase
13
porphobilinogenase
12
catalase
11
heme oxygenase
9
glutamyl-tRNA reductase
7
superoxide dismutase
6
hypoxanthine-guanine phosphoribosyltransferase
6
tyrosinase
6
luciferase
6
reverse transcriptase
6
coproporphyrinogen III oxidase
5
succinate dehydrogenase
5
proteasome
4
glutathione reductase
4
RNA polymerase
4
Mg-chelatase
4
lactate dehydrogenase
3
focal adhesion kinase
3
transcriptase
3
chlorophyllase
3
peroxidase
2
alanine aminotransferase
2
ERK
2
collagenase
2
endonuclease
2
glucose-6-phosphate dehydrogenase
2
protochlorophyllide oxidoreductase
2
cystathionine beta-synthase
2
more...
Compound
DNA
83
Clin
71
delta-aminolevulinic acid
52
Dec
46
iron
24
PBG
19
oxygen
17
cysteine
17
sodium
16
Heme
16
zinc
16
hydroxymethylbilane
15
HIS
14
water
12
phosphate
11
coproporphyrinogen III
10
uroporphyrin I
9
glucose
9
glutamate
9
His
8
methionine
8
acetate
7
sulfate
7
arginine
7
butyric acid
7
phenol
6
ammonium
5
butyric acid
5
benzene
5
DMSO
5
Luminal
5
NH2
5
butyric acid
5
lysine
5
hydroquinone
5
Protoporphyrin IX
5
DEAE
5
Chlorophyll
5
nitrogen
5
Lead
4
more...