Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:2.5.1.61 (porphobilinogen deaminase)
 637 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
porphobilinogen deaminase 439
hydroxymethylbilane synthase 137
PBG 87
erythroid 78
Mol 70
ferrochelatase 52
Sep 43
PCT 40
housekeeping 33
UPS 32
uroporphyrinogen III synthase 30
ALA 28
delta-aminolevulinic acid dehydratase 28
protoporphyrinogen oxidase 20
hemoglobin 20
HMBS 19
porphobilinogen synthase 19
NF-E2 16
coproporphyrinogen oxidase 15
beta-globin 14
delta-aminolevulinate synthase 13
GATA-1 13
variegate porphyria 13
polypeptide 13
glyceraldehyde-3-phosphate dehydrogenase 13
catalase 11
gamma-globin 10
erythropoietin 10
cytochrome P450 9
heme oxygenase-1 9
Gen 9
microsomal 8
cytochrome P-450 7
beta-2-microglobulin 7
transferrin receptor 7
endoplasmic reticulum 6
fused 6
superoxide dismutase 6
ferritin 6
erythropoietin receptor 6
tyrosinase 6
cyclophilin A 6
reductase 6
HPRT 5
cytochrome 5
axonal 5
ALAS1 5
AIP 5
beta-actin 5
tRNA 5
MRI 5
ubiquitin C 4
glutathione reductase 4
NAD 4
B12 4
B2M 4
Uroporphyrinogen decarboxylase 4
methyltransferase 4
hypoxanthine-guanine phosphoribosyltransferase 4
cryptic 4
Ferrochelatase 4
NF-E1 4
proteasome 4
NMR 4
cytokine 4
glycophorin B 3
AP1 3
14-3-3 zeta 3
pseudogene 3
ribosomal protein 3
glycophorin A 3
ACTB 3
interferon 3
HS2 3
transferrin 3
NADPH 3
TBP 3
progesterone receptor 3
transcriptional activator 3
tumor necrosis factor 3
Sp1 3
p45 NF-E2 3
ATP 3
GATA1 3
beta-2 microglobulin 3
P450 3
MEL 3
GPA 2
Polymerase 2
ribosomal protein L13a 2
beta actin 2
She 2
lymphoid 2
Maf 2
CD34 2
UROD 2
MART-1 2
peroxidase 2
Cytokine 2
peptidylprolyl isomerase A 2
nuclear protein 2
ATP synthase 2
UTR 2
ribosomal protein L4 2
ubiquitously expressed transcript 2
esterase 2
telomerase catalytic subunit 2
unknown function 2
cytochrome c-1 2
SDHA 2
heme synthetase 2
endonuclease 2
RPS9 2
NADP 2
protamine 2 2
beta globin 2
H2A.X 2
ERK 2
ES2 2
MIM 2
vasopressin 2
breakpoint cluster region 2
EKLF 2
ferredoxin 2
CYP1A1 2
alanine aminotransferase 2
ETS1 2
AML 2
annexin V 2
YWHAZ 2
JAMA 2
insulin-like growth factor I 2
GATA-2 2
hinge 2
ALAS-E 2
Protoporphyrinogen oxidase 2
histone 2
neural cell adhesion molecule 2
hypoxanthine phosphoribosyltransferase 1 2
epidermal growth factor receptor 2
mucin 4 2
zinc finger protein 2
transcription factor GATA-1 2
glycoprotein 2
ALAD 2
Delta-aminolevulinic acid dehydratase 2
A-I 2
hTERT 2
p53 2
STR 2
GAPDH 2
telomerase reverse transcriptase 2
DNase I 2
DNase 2
HIS3 2
c-myc 2
dopamine D2 receptor 2
AP-1 2
collagenase 2
TCF11 2
X-linked 2
Pol 2
membrane-bound 2
P22 2
ribonucleotide reductase 1
SP1 1
SOCS-2 1
aryl hydrocarbon receptor 1
mucin 1
cAMP-dependent protein kinase 1
non-catalytic 1
factor VII 1
regulator of G-protein signaling 3 1
MSP 1
p38IP 1
complement component C3 1
TGA 1
Bos taurus 1
TRA 1
AF9 1
REST 1
guanylate cyclase 1
MMP7 1
ESI 1
ABL 1
TGP 1
serine dehydratase 1
IL-10 1
p45 1
thyroglobulin 1
SRS 1
non-protein coding 1
gp100 1
extracellular signal-regulated kinase 1 1
UXT 1
NADH 1
Arnt 1
epsilon-globin 1
ALG8 1
LIM and SH3 protein 1 1
ATP5B 1
dermcidin 1
COXII 1
MAP 1
succinate dehydrogenase complex subunit A 1
apoE 1
DNA-binding protein 1
T3D 1
integral membrane protein 1
Noelin 1
neu 1
GPIIIa 1
P1-450 1
suppressor of cytokine signaling 1
cell surface glycoprotein 1
prohibitin 1
NADP-dependent malic enzyme 1
somatomedin C 1
THY1 1
Nrf2 1
suppressor of cytokine signaling 3 1
ABC transporter 1
muscle creatine kinase 1
IGF-1 1
HEM1 1
actin beta 1
proline-rich 1
ATP synthase 6 1
reserved 1
apolipoprotein 1
p22 1
pantothenate kinase 1
alpha-chain 1
fibronectin 1
ferroportin1 1
loricrin 1
hormone receptor 1
polycomb group protein 1
stromelysin 1
c-myc mRNA 1
transglutaminase 1
zinc finger 1
thymidine kinase 1
glucose-6-phosphate dehydrogenase 1
40 kDa) 1
malate dehydrogenase 1
BCR 1
TOF 1
c-fos 1
LDHA 1
Oct-2 1
AP4 1
plasminogen activator inhibitor-1 1
apolipoprotein E 1
decarboxylating 1
cardiac muscle 1
poly (ADP-ribose) polymerase 1
Cytochrome b5 1
prolactin 1
GABA transport protein 1
LIM domain protein 1
H-ras 1
BPGM 1
c-myb 1
ornithine decarboxylase 1
CD14 1
proteasome inhibitor 1
AGRN 1
RPS23 1
LEU2 1
prothrombin 1
gamma2 1
SPTA1 1
MLL 1
Met 1
TGF-beta 1
PPARA 1
single-stranded DNA binding protein 1
AIR 1
peptidase 1
precursor protein 1
DBA 1
inducible nitric oxide synthase 1
BRCA1 1
CD8B 1
proline rich 1
KLF13 1
caspase-3 1
p13 1
MT-CO2 1
ribosomal protein L29 1
San 1
chorionic gonadotropin 1
gamma, delta 1
beta-glucuronidase 1
cytokeratin 19 1
IL-8 1
peptidoglycan recognition protein 1
RPL35 1
LDH 1
DNA-binding domain 1
CACC 1
MRPL39 1
DNA methyltransferase 1
bcr/abl 1
IGF-I 1
ACP 1
proinsulin 1
HEMO 1
kit 1
alpha-fetoprotein 1
TRE 1
insulin-like growth factor 1
CYP1B1 1
retinoic acid receptor alpha 1
DOK7 1
ATPase 1
IL-4 1
H2AFZ 1
neurofibromatosis 1
more...
Disease
acute intermittent porphyria 247
porphyria 83
cancer 37
tumor 22
hepatic porphyria 17
anemia 17
neuropathy 16
variegate porphyria 16
porphyria cutanea tarda 15
CEP 10
coproporphyria 10
erythroleukemia 10
hepatocellular carcinoma 10
schizophrenia 9
leukemia 9
enzyme deficiency 9
depression 8
peripheral neuropathy 8
AIP 8
adenocarcinoma 8
hypertension 7
encephalopathy 6
photosensitivity 6
melanoma 6
liver disease 6
AIP 5
renal failure 5
psychosis 5
carcinoma 5
metabolic disorder 5
genetic disorder 4
tumorigenesis 4
breast cancer 4
uremia 4
diabetes 4
erythropoietic protoporphyria 4
lymphoma 4
hemolytic anemia 3
chronic renal failure 3
malnutrition 3
glioblastoma 3
chronic myeloid leukemia 3
renal disease 3
respiratory failure 3
minimal residual disease 3
polyneuropathy 3
tetraplegia 3
Barrett's esophagus 3
Leukemia 3
cirrhosis 3
epilepsy 2
mammary tumor 2
Melanoma 2
Hereditary coproporphyria 2
DBA 2
hyperbilirubinemia 2
colorectal cancer 2
fits 2
pheochromocytoma 2
malaria 2
delirium 2
MCF 2
Epstein 2
dehydration 2
Friend leukemia 2
psychiatric diagnosis 2
neuroblastoma 2
trisomy 2
glioma 2
Posterior 2
Pineal 2
infectious diseases 2
bladder cancer 2
iron deficiency 2
acute myeloid leukemia 2
West 2
coma 2
mesothelioma 2
mental illness 2
Dubin-Johnson syndrome 2
Blocking 1
adenoma 1
mild mental retardation 1
virus infection 1
spotted fever 1
Friedreich's ataxia 1
sideroblastic anemia 1
lung carcinoma 1
neurofibrosarcoma 1
proteinuria 1
chlorosis 1
acute hepatitis 1
Hodgkin's disease 1
polycystic kidney 1
cholecystitis 1
gallstones 1
Luminal 1
cholestasis 1
stuttering 1
cytomegalovirus 1
polyarthritis 1
chronic active hepatitis 1
appendicitis 1
Proteinuria 1
chronic renal insufficiency 1
rash 1
retinoblastoma 1
homocystinuria 1
arteriosclerosis 1
B-cell lymphoma 1
rheumatoid arthritis 1
ichthyosis 1
CCD 1
primary tumor 1
bipolar disorder 1
MCS 1
hepatitis B 1
chronic liver disease 1
RARS 1
PML 1
neuroticism 1
tyrosinemia 1
ACP 1
viral hepatitis 1
aldosteronism 1
lymphoproliferative disorders 1
neurofibromatosis type 1 1
CCD 1
SEM 1
Testis 1
plexiform neurofibroma 1
blindness 1
chronic lymphocytic leukemia 1
metastases 1
autism 1
tuberculosis 1
lymphoblastic leukemia 1
multiple sclerosis 1
PDB 1
hypercholesterolemia 1
muscular atrophy 1
hypothyroidism 1
Mycobacterium 1
Hepatocellular carcinoma 1
tumor progression 1
hysteria 1
SIADH 1
acute lymphoblastic leukemia 1
carcinogenesis 1
lung cancer 1
quadriparesis 1
renal insufficiency 1
Photosensitization 1
lymphosarcoma 1
chronic pain 1
SRS 1
ichthyosis 1
rare disease 1
Evans 1
chronic lymphocytic leukemia 1
sinus tachycardia 1
Pituitary 1
incontinence 1
pancreatitis 1
sick building syndrome 1
confusion 1
measles 1
anaplastic astrocytoma 1
cerebral ischemia 1
paraplegia 1
Fanconi 1
tumor growth 1
acute promyelocytic leukemia 1
schizoaffective disorder 1
EMT 1
liposarcoma 1
lymphadenopathy 1
biliary obstruction 1
renal clear cell carcinoma 1
ABL 1
solid tumor 1
laryngeal cancer 1
cold 1
conversion reaction 1
Alzheimer's disease 1
plaque 1
iron overload 1
fibrosarcoma 1
MCS 1
SDS 1
microcytic anemia 1
peritonitis 1
Tonsil 1
siderosis 1
hematologic malignancies 1
organic disease 1
Testis 1
liver cancer 1
bowel obstruction 1
Acute encephalopathy 1
laryngeal cancer 1
hypertensive encephalopathy 1
dysautonomia 1
non-Hodgkin's lymphoma 1
ischemia 1
histrionic personality disorder 1
Fox 1
Symptom
abdominal pain 30
seizures 8
vomiting 8
pain 7
weakness 5
starvation 4
constipation 4
anesthesia 4
nausea 4
acute abdominal pain 3
acute abdomen 2
agitation 2
headache 2
arthralgia 1
sleepiness 1
ataxia 1
stomach pain 1
fever of unknown origin 1
Physical findings 1
acidity 1
astasia 1
hepatosplenomegaly 1
HSA 1
paresis 1
erythema 1
paresthesia 1
myalgia 1
chills 1
colic 1
generalized abdominal pain 1
Drug
ALA 34
Heme 15
lysine 4
Leaf 3
Dermatol 3
VCR 2
DNase I 2
NADH 1
IFN-gamma 1
IL-2 1
Pyridoxal 1
Vitamin B 1
ascorbate 1
Alanine 1
Paraffin 1
MAP 1
CSF 1
ROS 1
Ethanol 1
NH3 1
Doxycycline 1
Capsicum 1
AMC 1
THF 1
Arsenic trioxide 1
IFN-beta 1
Enzyme
porphobilinogen deaminase 637
ALA synthase 58
ferrochelatase 52
delta-aminolevulinic acid dehydratase 49
uroporphyrinogen decarboxylase 43
protoporphyrinogen oxidase 21
coproporphyrinogen oxidase 20
deaminase 18
glyceraldehyde-3-phosphate dehydrogenase 14
glyceraldehyde-3-phosphate dehydrogenase 13
glyceraldehyde-3-phosphate dehydrogenase 13
glyceraldehyde-3-phosphate dehydrogenase 13
glyceraldehyde-3-phosphate dehydrogenase 13
porphobilinogenase 12
catalase 11
heme oxygenase 9
glutamyl-tRNA reductase 7
tyrosinase 6
reverse transcriptase 6
superoxide dismutase 6
hypoxanthine-guanine phosphoribosyltransferase 6
luciferase 6
succinate dehydrogenase 5
coproporphyrinogen III oxidase 5
RNA polymerase 4
glutathione reductase 4
proteasome 4
Mg-chelatase 4
chlorophyllase 3
focal adhesion kinase 3
transcriptase 3
lactate dehydrogenase 3
ERK 2
cystathionine beta-synthase 2
alanine aminotransferase 2
endonuclease 2
collagenase 2
glucose-6-phosphate dehydrogenase 2
peroxidase 2
demethylase 2
protochlorophyllide oxidoreductase 2
ATP synthase 2
DNase 2
ECH 1
TMT 1
tryptophan synthase 1
cysteine synthase 1
MCS 1
phosphoglycerate kinase 1
GLO 1
NADPH oxidase 1
glutamate dehydrogenase 1
glutamate dehydrogenase 1
phosphoglyceromutase 1
RNase 1
protein kinase 1
SPC 1
SirB 1
arginase 1
glutamate-1-semialdehyde aminotransferase 1
CysG 1
ornithine decarboxylase 1
CEP 1
nicotinamidase 1
glutamate formiminotransferase 1
Lod 1
monoamine oxidase 1
L-serine dehydratase 1
enoyl-ACP reductase 1
L-serine hydro-lyase 1
beta-glucuronidase 1
MMP-3 1
cobaltochelatase 1
mannonate dehydratase 1
AMPK 1
glutamate dehydrogenase 1
firefly luciferase 1
peroxiredoxin 1
NADPH oxidase 1
rhodanese 1
pepsin 1
peptidyl-prolyl cis-trans isomerase 1
cystathionine gamma-synthase 1
ribonucleotide reductase 1
acetylcholinesterase 1
ascorbate peroxidase 1
ribonucleotide reductase 1
DNA methyltransferase 1
ADP-glucose pyrophosphorylase 1
rubisco 1
carbonic anhydrase 1
transglutaminase 1
RNase 1
TdT 1
MAP 1
nitrite reductase 1
CEP 1
glutathione peroxidase 1
glycolate oxidase 1
trypsin 1
lipoxygenase 1
alkaline phosphatase 1
thymidine kinase 1
phosphoribulokinase 1
malate dehydrogenase 1
glutathione S-transferase 1
PRA 1
nitrite reductase 1
pantothenate kinase 1
guanylate cyclase 1
nitrite reductase 1
MEK 1
phenylalanine hydroxylase 1
enoyl-ACP reductase 1
citrate synthase 1
ATPase 1
calcineurin 1
CbiX 1
Compound
DNA 83
Clin 71
delta-aminolevulinic acid 52
Dec 46
iron 24
PBG 19
oxygen 17
cysteine 17
sodium 16
Heme 16
zinc 16
hydroxymethylbilane 15
HIS 14
water 12
phosphate 11
coproporphyrinogen III 10
uroporphyrin I 9
glutamate 9
glucose 9
methionine 8
His 8
acetate 7
butyric acid 7
sulfate 7
arginine 7
phenol 6
DMSO 5
benzene 5
Luminal 5
ammonium 5
DEAE 5
butyric acid 5
Protoporphyrin IX 5
Chlorophyll 5
nitrogen 5
lysine 5
hydroquinone 5
butyric acid 5
NH2 5
leucine 4
NAD 4
Asp 4
Lead 4
NAD 4
alanine 4
Uroporphyrinogen III 4
salt 4
aniline 3
ethanol 3
Porphyrin 3
NADPH 3
TBP 3
EDTA 3
tryptophan 3
tryptophan 3
Porphyrin 3
Benzene 3
CoA 3
Ile 3
NADPH 3
Gly 3
hydrogen 3
glutamine 3
tryptophan 3
proline 3
isoleucine 3
EDTA 3
PDT 3
tryptophan 3
isoleucine 3
silver 3
TBP 3
serine 3
HCl 3
galactose 3
MTT 3
1,2,4-benzenetriol 3
ATP 3
Bisphenol A 2
LCR 2
glycerol 2
formaldehyde 2
copper 2
NADP 2
nitric oxide 2
calcium 2
hydroxide 2
Bisphenol A 2
urea 2
tyrosine 2
TCA 2
creatinine 2
selenium 2
valine 2
nitrate 2
PEG 2
asparagine 2
formaldehyde 2
potassium 2
COS 2
aspartic acid 2
pyrene 2
Neurotol 2
corrin 2
Ehrlich's reagent 2
cobalt 2
phenanthrene 1
protoporphyrinogen IX 1
Tris 1
Pantothenate 1
Guo 1
ornithine 1
Benzidine 1
Tamoxifen 1
Phenylhydrazine 1
Mg2+ 1
Melatonin 1
Bilirubin 1
5-HIAA 1
bromide 1
FAP 1
Chlorophyll b 1
manganese 1
pentose 1
acetonitrile 1
aldehyde 1
ornithine 1
DSM 1
cyclohexanone 1
BCR 1
cyclohexanone 1
cyanide 1
DBA 1
NADH 1
Chrysin 1
Doxycycline 1
A 1 1
TOF 1
ethyl acetate 1
dicarboxylic acid 1
ENU 1
Tellimagrandin I 1
Hemin 1
nonanoic acid 1
cyclohexanone 1
Hemin 1
mercury 1
Cysteine 1
FAP 1
AIR 1
Alanine 1
pentose 1
PGA 1
THF 1
DTT 1
Hemin 1
Resveratrol 1
N'-methylnicotinamide 1
cyclohexanone 1
TNF 1
homocysteine 1
Chlorophyll b 1
Danazol 1
Triton X-100 1
Tamoxifen 1
Hemin 1
phosphoric acid 1
LTC4 1
Androgen 1
2-mercaptoethanol 1
hydroxylamine 1
Arsenite 1
2-oxoglutarate 1
DPA 1
UGA 1
Catechol 1
DPM 1
DBA 1
cyclohexanone 1
ABL 1
thioglycollate 1
cyclohexanone 1
S-adenosylhomocysteine 1
Succinylacetone 1
dATP 1
Guo 1
HBC 1
pentose 1
DBA 1
acetone 1
ammonia 1
chloroform 1
silicon 1
Tris 1
retinol 1
Proline 1
Hemin 1
MEK 1
iodine 1
carbonate 1
Histone 1
Pyridoxal 1
Cobalt 1
Malondialdehyde 1
sodium chloride 1
methanol 1
TAA 1
ornithine 1
Genistein 1
Cyt 1
adenosylmethionine 1
cyclohexanone 1
cyclohexanone 1
THP 1
ASA 1
ornithine 1
BeCl2 1
Catechol 1
ornithine 1
DTT 1
A 3 1
GlcNAc 1
heptane 1
N-Acetylglucosamine 1
MAP 1
phosphorus 1
Arsenic 1
cyclohexanone 1
Optimal 1
pentose 1
cadmium 1
SDS 1
acetaldehyde 1
PDB 1
Chlorophyll b 1
hydroxylamine 1
Protochlorophyllide 1
Triton 1