Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:2.5.1.61 (porphobilinogen deaminase)
 637 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
porphobilinogen deaminase 439
hydroxymethylbilane synthase 137
PBG 87
erythroid 78
Mol 70
ferrochelatase 52
Sep 43
PCT 40
housekeeping 33
UPS 32
uroporphyrinogen III synthase 30
delta-aminolevulinic acid dehydratase 28
ALA 28
hemoglobin 20
protoporphyrinogen oxidase 20
porphobilinogen synthase 19
HMBS 19
NF-E2 16
coproporphyrinogen oxidase 15
beta-globin 14
variegate porphyria 13
polypeptide 13
glyceraldehyde-3-phosphate dehydrogenase 13
delta-aminolevulinate synthase 13
GATA-1 13
catalase 11
gamma-globin 10
erythropoietin 10
Gen 9
heme oxygenase-1 9
cytochrome P450 9
microsomal 8
cytochrome P-450 7
beta-2-microglobulin 7
transferrin receptor 7
erythropoietin receptor 6
cyclophilin A 6
fused 6
endoplasmic reticulum 6
tyrosinase 6
superoxide dismutase 6
ferritin 6
reductase 6
axonal 5
AIP 5
cytochrome 5
beta-actin 5
tRNA 5
MRI 5
HPRT 5
ALAS1 5
Ferrochelatase 4
B2M 4
NAD 4
NF-E1 4
B12 4
proteasome 4
cryptic 4
ubiquitin C 4
cytokine 4
NMR 4
glutathione reductase 4
hypoxanthine-guanine phosphoribosyltransferase 4
methyltransferase 4
Uroporphyrinogen decarboxylase 4
transcriptional activator 3
beta-2 microglobulin 3
glycophorin B 3
transferrin 3
P450 3
ribosomal protein 3
MEL 3
glycophorin A 3
14-3-3 zeta 3
HS2 3
Sp1 3
p45 NF-E2 3
ATP 3
GATA1 3
tumor necrosis factor 3
progesterone receptor 3
pseudogene 3
ACTB 3
NADPH 3
TBP 3
interferon 3
AP1 3
neural cell adhesion molecule 2
mucin 4 2
ERK 2
beta globin 2
Polymerase 2
Cytokine 2
transcription factor GATA-1 2
cytochrome c-1 2
Delta-aminolevulinic acid dehydratase 2
peroxidase 2
ALAD 2
hypoxanthine phosphoribosyltransferase 1 2
nuclear protein 2
She 2
breakpoint cluster region 2
alanine aminotransferase 2
A-I 2
p53 2
Maf 2
AML 2
ribosomal protein L4 2
DNase I 2
dopamine D2 receptor 2
DNase 2
GPA 2
epidermal growth factor receptor 2
collagenase 2
TCF11 2
ubiquitously expressed transcript 2
AP-1 2
beta actin 2
SDHA 2
JAMA 2
insulin-like growth factor I 2
endonuclease 2
CD34 2
c-myc 2
UROD 2
ES2 2
MIM 2
ribosomal protein L13a 2
CYP1A1 2
EKLF 2
ETS1 2
peptidylprolyl isomerase A 2
annexin V 2
protamine 2 2
YWHAZ 2
NADP 2
glycoprotein 2
telomerase reverse transcriptase 2
hTERT 2
HIS3 2
MART-1 2
H2A.X 2
Pol 2
zinc finger protein 2
ATP synthase 2
histone 2
STR 2
ferredoxin 2
lymphoid 2
GAPDH 2
GATA-2 2
vasopressin 2
RPS9 2
telomerase catalytic subunit 2
unknown function 2
esterase 2
UTR 2
X-linked 2
heme synthetase 2
membrane-bound 2
more...
Disease
acute intermittent porphyria 247
porphyria 83
cancer 37
tumor 22
anemia 17
hepatic porphyria 17
neuropathy 16
variegate porphyria 16
porphyria cutanea tarda 15
erythroleukemia 10
CEP 10
hepatocellular carcinoma 10
coproporphyria 10
enzyme deficiency 9
leukemia 9
schizophrenia 9
AIP 8
depression 8
peripheral neuropathy 8
adenocarcinoma 8
hypertension 7
photosensitivity 6
encephalopathy 6
melanoma 6
liver disease 6
psychosis 5
carcinoma 5
renal failure 5
metabolic disorder 5
AIP 5
tumorigenesis 4
diabetes 4
genetic disorder 4
uremia 4
erythropoietic protoporphyria 4
breast cancer 4
lymphoma 4
polyneuropathy 3
hemolytic anemia 3
glioblastoma 3
malnutrition 3
tetraplegia 3
respiratory failure 3
chronic renal failure 3
renal disease 3
minimal residual disease 3
Barrett's esophagus 3
chronic myeloid leukemia 3
Leukemia 3
cirrhosis 3
pheochromocytoma 2
Melanoma 2
coma 2
Hereditary coproporphyria 2
dehydration 2
psychiatric diagnosis 2
DBA 2
mammary tumor 2
fits 2
delirium 2
malaria 2
bladder cancer 2
trisomy 2
Epstein 2
acute myeloid leukemia 2
neuroblastoma 2
hyperbilirubinemia 2
glioma 2
Posterior 2
Pineal 2
colorectal cancer 2
infectious diseases 2
Friend leukemia 2
iron deficiency 2
epilepsy 2
West 2
MCF 2
mesothelioma 2
mental illness 2
Dubin-Johnson syndrome 2
Blocking 1
adenoma 1
mild mental retardation 1
virus infection 1
spotted fever 1
Friedreich's ataxia 1
sideroblastic anemia 1
lung carcinoma 1
neurofibrosarcoma 1
proteinuria 1
chlorosis 1
acute hepatitis 1
Hodgkin's disease 1
polycystic kidney 1
cholecystitis 1
gallstones 1
Luminal 1
cholestasis 1
stuttering 1
cytomegalovirus 1
polyarthritis 1
chronic active hepatitis 1
appendicitis 1
Proteinuria 1
chronic renal insufficiency 1
rash 1
retinoblastoma 1
homocystinuria 1
arteriosclerosis 1
B-cell lymphoma 1
lymphosarcoma 1
SRS 1
ichthyosis 1
bipolar disorder 1
MCS 1
ichthyosis 1
Pituitary 1
PML 1
neuroticism 1
tyrosinemia 1
viral hepatitis 1
blindness 1
CCD 1
SEM 1
aldosteronism 1
lymphoproliferative disorders 1
neurofibromatosis type 1 1
conversion reaction 1
tuberculosis 1
laryngeal cancer 1
carcinogenesis 1
lung cancer 1
SIADH 1
Testis 1
plexiform neurofibroma 1
fibrosarcoma 1
Evans 1
multiple sclerosis 1
PDB 1
hypercholesterolemia 1
incontinence 1
sick building syndrome 1
muscular atrophy 1
hypothyroidism 1
Mycobacterium 1
Hepatocellular carcinoma 1
tumor progression 1
hysteria 1
siderosis 1
measles 1
Photosensitization 1
paraplegia 1
Fanconi 1
Acute encephalopathy 1
tumor growth 1
schizoaffective disorder 1
EMT 1
liposarcoma 1
lymphadenopathy 1
biliary obstruction 1
more...
Symptom
abdominal pain 30
seizures 8
vomiting 8
pain 7
weakness 5
starvation 4
constipation 4
anesthesia 4
nausea 4
acute abdominal pain 3
acute abdomen 2
agitation 2
headache 2
arthralgia 1
sleepiness 1
ataxia 1
stomach pain 1
fever of unknown origin 1
Physical findings 1
acidity 1
astasia 1
hepatosplenomegaly 1
HSA 1
paresis 1
erythema 1
paresthesia 1
myalgia 1
chills 1
colic 1
generalized abdominal pain 1
Drug
ALA 34
Heme 15
lysine 4
Leaf 3
Dermatol 3
VCR 2
DNase I 2
NADH 1
IFN-gamma 1
IL-2 1
Pyridoxal 1
Vitamin B 1
ascorbate 1
Alanine 1
Paraffin 1
MAP 1
CSF 1
ROS 1
Ethanol 1
NH3 1
Doxycycline 1
Capsicum 1
AMC 1
THF 1
Arsenic trioxide 1
IFN-beta 1
Enzyme
porphobilinogen deaminase 637
ALA synthase 58
ferrochelatase 52
delta-aminolevulinic acid dehydratase 49
uroporphyrinogen decarboxylase 43
protoporphyrinogen oxidase 21
coproporphyrinogen oxidase 20
deaminase 18
glyceraldehyde-3-phosphate dehydrogenase 14
glyceraldehyde-3-phosphate dehydrogenase 13
glyceraldehyde-3-phosphate dehydrogenase 13
glyceraldehyde-3-phosphate dehydrogenase 13
glyceraldehyde-3-phosphate dehydrogenase 13
porphobilinogenase 12
catalase 11
heme oxygenase 9
glutamyl-tRNA reductase 7
tyrosinase 6
reverse transcriptase 6
superoxide dismutase 6
hypoxanthine-guanine phosphoribosyltransferase 6
luciferase 6
succinate dehydrogenase 5
coproporphyrinogen III oxidase 5
RNA polymerase 4
glutathione reductase 4
proteasome 4
Mg-chelatase 4
chlorophyllase 3
focal adhesion kinase 3
transcriptase 3
lactate dehydrogenase 3
ERK 2
cystathionine beta-synthase 2
alanine aminotransferase 2
endonuclease 2
collagenase 2
glucose-6-phosphate dehydrogenase 2
peroxidase 2
demethylase 2
protochlorophyllide oxidoreductase 2
ATP synthase 2
DNase 2
ECH 1
TMT 1
tryptophan synthase 1
cysteine synthase 1
MCS 1
phosphoglycerate kinase 1
GLO 1
NADPH oxidase 1
glutamate dehydrogenase 1
glutamate dehydrogenase 1
phosphoglyceromutase 1
RNase 1
protein kinase 1
SPC 1
SirB 1
arginase 1
glutamate-1-semialdehyde aminotransferase 1
CysG 1
ornithine decarboxylase 1
CEP 1
nicotinamidase 1
glutamate formiminotransferase 1
Lod 1
monoamine oxidase 1
L-serine dehydratase 1
enoyl-ACP reductase 1
L-serine hydro-lyase 1
beta-glucuronidase 1
MMP-3 1
cobaltochelatase 1
mannonate dehydratase 1
AMPK 1
glutamate dehydrogenase 1
firefly luciferase 1
peroxiredoxin 1
NADPH oxidase 1
rhodanese 1
pepsin 1
peptidyl-prolyl cis-trans isomerase 1
cystathionine gamma-synthase 1
ribonucleotide reductase 1
acetylcholinesterase 1
ascorbate peroxidase 1
ribonucleotide reductase 1
DNA methyltransferase 1
ADP-glucose pyrophosphorylase 1
rubisco 1
carbonic anhydrase 1
transglutaminase 1
RNase 1
TdT 1
MAP 1
nitrite reductase 1
CEP 1
glutathione peroxidase 1
glycolate oxidase 1
trypsin 1
lipoxygenase 1
alkaline phosphatase 1
thymidine kinase 1
phosphoribulokinase 1
malate dehydrogenase 1
glutathione S-transferase 1
PRA 1
nitrite reductase 1
pantothenate kinase 1
guanylate cyclase 1
nitrite reductase 1
MEK 1
phenylalanine hydroxylase 1
enoyl-ACP reductase 1
citrate synthase 1
ATPase 1
calcineurin 1
CbiX 1
Compound
DNA 83
Clin 71
delta-aminolevulinic acid 52
Dec 46
iron 24
PBG 19
oxygen 17
cysteine 17
sodium 16
zinc 16
Heme 16
hydroxymethylbilane 15
HIS 14
water 12
phosphate 11
coproporphyrinogen III 10
glucose 9
glutamate 9
uroporphyrin I 9
His 8
methionine 8
sulfate 7
arginine 7
butyric acid 7
acetate 7
phenol 6
hydroquinone 5
nitrogen 5
DEAE 5
butyric acid 5
Chlorophyll 5
Protoporphyrin IX 5
lysine 5
butyric acid 5
NH2 5
Luminal 5
benzene 5
ammonium 5
DMSO 5
NAD 4
leucine 4
alanine 4
Asp 4
salt 4
Uroporphyrinogen III 4
Lead 4
NAD 4
EDTA 3
tryptophan 3
Porphyrin 3
hydrogen 3
TBP 3
EDTA 3
tryptophan 3
glutamine 3
tryptophan 3
Porphyrin 3
Ile 3
Benzene 3
CoA 3
isoleucine 3
NADPH 3
serine 3
Gly 3
PDT 3
TBP 3
aniline 3
NADPH 3
proline 3
silver 3
tryptophan 3
HCl 3
galactose 3
isoleucine 3
1,2,4-benzenetriol 3
ethanol 3
MTT 3
ATP 3
Bisphenol A 2
LCR 2
glycerol 2
formaldehyde 2
copper 2
NADP 2
nitric oxide 2
calcium 2
tyrosine 2
creatinine 2
PEG 2
pyrene 2
asparagine 2
potassium 2
corrin 2
aspartic acid 2
COS 2
selenium 2
formaldehyde 2
nitrate 2
Neurotol 2
Bisphenol A 2
valine 2
hydroxide 2
TCA 2
urea 2
Ehrlich's reagent 2
cobalt 2
phenanthrene 1
protoporphyrinogen IX 1
Tris 1
Pantothenate 1
Guo 1
ornithine 1
Benzidine 1
Tamoxifen 1
Phenylhydrazine 1
Mg2+ 1
Melatonin 1
Bilirubin 1
5-HIAA 1
bromide 1
FAP 1
Chlorophyll b 1
manganese 1
pentose 1
acetonitrile 1
aldehyde 1
ornithine 1
DSM 1
cyclohexanone 1
BCR 1
cyclohexanone 1
cyanide 1
DBA 1
NADH 1
Chrysin 1
Doxycycline 1
TOF 1
A 1 1
Tellimagrandin I 1
Tamoxifen 1
cyclohexanone 1
2-mercaptoethanol 1
Alanine 1
pentose 1
Catechol 1
cyclohexanone 1
mercury 1
DTT 1
Hemin 1
cyclohexanone 1
TNF 1
thioglycollate 1
Chlorophyll b 1
Danazol 1
Guo 1
phosphoric acid 1
Arsenite 1
ammonia 1
Hemin 1
carbonate 1
more...