Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:2.5.1.18 (glutathione S-transferase)
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Human Gene/Protein
FHL3 protein 10.5
ISG12 protein 10.5
vacuolar ATP synthase subunit D 10.5
nephronophthisis 3 10.5
LINCR 10.5
Chloride intracellular channel 2 10.5
hSnf7-3 10.5
HBP21 10.5
transforming growth factor, alpha 10.5
C1orf121 10.5
dolichyl-phosphate beta-glucosyltransferase 10.5
Down syndrome critical region gene 1-like 2 10.5
Rab9 effector p40 10.5
GSTT4 10.5
GST class-alpha 10.5
Glutathione S-alkyltransferase 10.5
FSD2 protein 10.5
fatty acid ethyl ester synthase-II 10.5
LDHAL6A protein 10.5
GST 13-13 10.5
MT-ACT48 10.5
KIAA0809 10.5
AHNAK-related protein 10.5
USP15 protein 10.5
glutathione transferase 10.5
GRB-IR 10.5
Glutathione S-transferase omega 2 10.5
EFEMP2 protein 10.5
C2orf62 10.5
KIAA0068 10.5
AMP deaminase 2 10.5
PhLOP2 10.5
TNFRSF10B protein 10.5
FLJ23654 10.5
C16orf63 10.5
tectonin beta-propeller repeat containing 1 10.5
tropomyosin 4 isoform 2 10.5
Ras-related protein Rab-34 10.5
HMGE 10.5
vacuolar protein sorting 28 10.5
glutathione S-transferase 10.5
V-type proton ATPase subunit E 1 10.5
gamma-glutamylcysteine synthetase light subunit 10.5
microsomal GST-III 10.5
COE4 10.5
phosphoinositide-3-kinase adaptor protein 1 10.5
FYVE, RhoGEF and PH domain containing 4 10.5
zinc finger protein 200 10.5
glutathione S-aryltransferase 10.5
trafficking protein particle complex 4 10.5
GST 10.5
membrane-associated multivalent-anchoring protein 10.5
Synaptotagmin XV 10.5
SLA protein 10.5
actin-related protein T2 10.5
PPP1R11 protein 10.5
glutathione S-transferase class theta 10.0
GSTT2B 10.0
glutathione S-transferase M4 10.0
GST T1 10.0
GST A4 9.9
GSTP1-1 9.9
GST mRNA 9.9
PhLOP1 9.9
TSBP 9.9
Glutathione transferase 9.8
PDIP46 9.7
GSTA5 9.7
mutant GSTP1 9.7
GST2 9.6
GSTK1-1 9.6
GSTA1-1 9.6
GST3 9.6
MGST3 9.6
Glutathione S-transferase pi 9.5
YPEL4 9.5
APC-binding protein EB1 9.5
hD55 9.5
PROCA1 9.5
GTP-binding protein SAR1 9.5
more...
Disease
GST6 9.0
Adult atopic dermatitis 8.9
Barrett's Adenocarcinoma 8.5
Barrett's Adenocarcinoma 8.5
Hypotriglyceridemia 8.1
Osmotic nephrosis 7.9
RP26 7.3
CMD1A 7.3
SSS1 7.1
Ketonemia 7.0
Dietary selenium deficiency 7.0
ter Haar syndrome 6.9
ACCCA 6.9
ADH3*2 6.8
Hepatocarcinogenesis 6.6
GSH 6.6
LIH 6.6
Schistosoma japonicum 6.5
CMT2K 6.5
PHA2 6.5
Essential mixed cryoglobulinemia 6.4
UVS 6.3
ADH3*1 6.1
RP23 6.1
chemical carcinogenesis 6.1
WTS 6.1
Farber 6.1
Fasciola gigantica infection 6.0
DTD 6.0
bone marrow cancer 5.9
Bovine ephemeral fever 5.9
Pleuropneumonia 5.9
EBSS 5.9
preneoplastic state 5.8
FHL3 5.7
partial trisomy 2p 5.7
Piscirickettsiosis 5.7
environmental carcinogenesis 5.6
connective tissue hyperplasia 5.6
IBR 5.5
hyperlysinemia 5.5
MODY4 5.5
AGS3 5.4
Hepatic necrosis 5.3
CLL progression 5.3
Obstructive nephropathy 5.3
SAMS 5.3
childhood ANLL 5.3
Chemotherapy-induced neutropenia 5.3
AIN 5.2
BDB 5.2
Dietary zinc deficiency 5.2
Liver mass 5.2
adult soft tissue sarcoma 5.1
DMAT 5.1
Sclerosing hemangioma 5.1
Crabs 5.1
FHL2 5.1
hepatic neoplasm 5.0
GDD 5.0
Selenium deficiency 5.0
angiectasis 5.0
CTPA 4.9
bad behavior 4.9
FDD 4.9
Congenital heart block 4.9
Severe pre-eclampsia 4.9
Steroid-resistant nephrotic syndrome 4.9
ovarian serous cystadenocarcinoma 4.9
coenurosis 4.9
Ehrlich Ascites Tumor 4.9
Classical swine fever 4.8
CMD1 4.8
Shope fibroma 4.8
Acute mesenteric ischemia 4.8
XPV 4.8
PAL 4.8
Nasal cavity 4.7
HOPS 4.7
congenital amegakaryocytic thrombocytopenia 4.7
more...
Symptom
upset stomach 5.6
Spots 2.6
abdominal cramps 2.4
autodigestion 2.2
loin pain 2.1
emaciation 2.0
Scratch 1.8
starvation 1.8
hyperoxia 1.7
Halo 1.6
rundown 1.5
Hudson 1.4
Anoxia 1.4
Fluctuation 1.2
persistent cough 1.2
hepatomegaly 1.1
partial seizure 1.0
polyuria 0.9
wrist pain 0.7
DNA marker 0.6
microbial colonization 0.4
tense 0.4
polydipsia 0.4
hypoproteinemia 0.3
acute stress 0.3
memory loss 0.2
tingling 0.1
bitter taste 0.0
Neuropathic pain -0.0
physical appearance -0.1
diarrhea -0.1
despair -0.2
menopausal symptoms -0.2
exhaustion -0.3
incoordination -0.3
collapse -0.4
acute abdominal pain -0.5
skin irritation -0.6
wheezing -0.8
masculinization -0.9
Wind -0.9
dry eye -0.9
knee pain -1.0
cachexia -1.0
hypotonia -1.1
HSA -1.1
acute abdomen -1.1
anesthesia -1.2
seizures -1.2
exertional dyspnea -1.3
anorexia -1.3
arthralgia -1.3
hypercapnia -1.5
apathy -1.5
chills -1.6
hypothermia -1.6
nausea -1.7
dizziness -1.8
respiratory distress -1.8
splenomegaly -1.8
angina -1.9
ataxia -1.9
insomnia -1.9
thinning -2.0
hunger -2.0
fatigue -2.0
tremor -2.1
vomiting -2.2
flushing -2.2
erythema -2.2
stigma -2.2
acidity -2.4
Welt -2.5
dystonia -2.6
syncope -2.7
nausea and vomiting -2.8
pain -2.8
constipation -2.9
discomfort -3.0
headache -3.0
more...
Drug
S-Hexylglutathione 10.5
S-Octylglutathione 10.5
Polygonum root 10.5
Isepamicin sulfate 9.5
Bromisoval 8.5
Mitogillin 8.1
Schisandra fruit 8.1
S-Methylcysteine 7.9
Valerianae radix 7.7
Actarit 7.5
Gemifloxacin mesylate 7.3
Glutathione 7.3
2-Butanol 7.0
Gluthathione 6.8
RXM 6.7
2,4,6-Tribromophenol 6.7
Calamine 6.4
Phenobarbital sodium 6.3
Equilenin 6.3
Vitamin-E 6.2
Nipradilol 6.1
Stannous chloride 6.0
Iron dextran 6.0
Flolan 5.9
Atrovent 5.8
Perhexiline maleate 5.8
Caraway 5.8
CTZ 5.7
Coal tar 5.5
Abamectin 5.3
Indoxacarb 5.3
Parsol 5.2
CPFX 5.2
Ciprofibrate 5.2
Gold sodium thiomalate 5.1
Cibacron Blue 4.9
1-Deoxynojirimycin 4.8
DDF 4.8
Lead acetate 4.7
Tannic acid 4.7
Tenidap 4.7
Furan 4.7
AKM 4.7
Tallow 4.7
Auranofin 4.7
Tiaprofenic acid 4.5
Hyoscyamine 4.5
Esculin 4.4
Dextran sulfate sodium 4.4
Brotizolam 4.4
Areca 4.4
Zebularine 4.3
Jujube 4.3
Florfenicol 4.3
CPFX 4.3
Myricetin 4.2
Fipronil 4.2
Hyoscyamine 4.2
Vitamin E 4.2
Fenbendazole 4.2
Clofibrate 4.1
Synthroid 4.0
ROS 4.0
VCR 4.0
Ziconotide 4.0
Deuterium oxide 4.0
Zinc sulfate 3.9
Bezafibrate 3.9
Zinc sulfate 3.9
Ginger 3.9
Lipidex 3.9
Nabumetone 3.9
PCB 3.8
Clove 3.8
Adriamycin 3.8
ascorbate 3.8
Paliperidone 3.7
Rutin 3.7
RFP 3.7
vitamin E 3.7
more...
Enzyme
EC 1.5.1.18 10.5
glutathione S-transferase 10.5
EC 3.1.2.7 10.5
mRNA (nucleoside-2'-O-)-methyltransferase 9.5
dichloromethane dehalogenase 9.5
PDA synthase 9.5
hepoxilin epoxide hydrolase 9.5
DDTase 9.2
maleylacetoacetate isomerase 9.2
MMA(V) reductase 9.0
cytochrome c methyltransferase 8.9
4NQO reductase 8.9
FAEES 8.5
calpain 4 8.5
UDP-glucose:dolichol phosphate glucosyltransferase 8.1
PAPS sulfotransferase 8.1
microsomal epoxide hydrolase 8.1
LTC4 synthase 7.9
SuyAB 7.9
aliphatic nitrilase 7.9
CYP12 7.9
4-nitrophenol hydroxylase 7.7
diaminopropionate ammonia-lyase 7.7
BAST I 7.7
complement subcomponent C1r 7.7
amine N-sulfotransferase 7.7
maleylpyruvate isomerase 7.6
glutathione reductase 7.5
4-aminobenzoate hydroxylase 7.5
soluble epoxide hydrolase 7.3
SMP-I 7.3
steroid isomerase 7.3
dehydroascorbate reductase 7.2
glyoxalase II 7.2
3-GT 7.1
2-alkenal reductase 7.0
UDP-glucuronosyltransferase 7.0
glutathione peroxidase 7.0
NADPH:quinone oxidoreductase 6.9
NQO1 6.9
alkene monooxygenase 6.8
EC 4.4.1.5 6.8
2-alkenal reductase 6.8
gamma-glutamylcysteine synthetase 6.7
phosphoacetylglucosamine mutase 6.7
homoglutathione synthetase 6.7
mycocerosic acid synthase 6.7
S-formylglutathione hydrolase 6.6
NAD+ synthetase 6.6
UDP-sulfoquinovose synthase 6.6
17-ketoreductase 6.5
aryl hydrocarbon hydroxylase 6.4
EC 3.6.1.29 6.4
progesterone hydroxylase 6.4
small monomeric GTPase 6.3
sucrose-phosphatase 6.3
ADP-ribosylarginine hydrolase 6.2
isoflavone reductase 6.2
cysteine synthase 6.1
long-chain acyl-coenzyme A dehydrogenase 6.1
2-nitropropane dioxygenase 6.1
EC 5.3.3.2 6.1
EC 1.14.11.11 6.1
ascorbate peroxidase 6.1
catalase 6.0
codeinone reductase 6.0
2-hydroxymuconic semialdehyde dehydrogenase 6.0
histidinol phosphate phosphatase 6.0
cysteine conjugate beta-lyase 6.0
dihydrodiol dehydrogenase 6.0
glutathione synthetase 6.0
3-hydroxyisobutyryl-CoA hydrolase 5.9
NAD+ synthetase 5.9
aminodeoxychorismate synthase 5.9
retinal dehydrogenase 5.9
flavanone 3-hydroxylase 5.9
carboxylesterase 5.9
flavonoid 3'-hydroxylase 5.9
PAPS reductase 5.9
GAR 5.8
more...
Compound
15-carboxy-13-isopropylatis-13-ene-17,18-dioic acid 10.5
o-Dinitrobenzene 10.5
2,5-Difluoronitrobenzene 10.5
2-bromooctane 10.5
Benoxacor 10.1
2,2,5-trimethyl-1,3-oxazolidine 9.5
Butrin 9.5
15-carboxy-13-isopropylatis-13-ene-17,18-dioic acid 9.5
1,2-Dichloro-4-nitrobenzene 9.5
Flurochloridone 9.5
3-fluoroquinoline 9.5
4-phenyl-3-buten-2-one 9.3
4-phenyl-3-buten-2-one 9.3
4-phenyl-3-buten-2-one 9.3
1-chloro-2,4-dinitrobenzene 9.2
S-Methylglutathione 9.1
4,6-dichloro-2-phenylpyrimidine 9.1
Stilbene oxide 9.0
5,10-dihydroindeno[1,2-b]indole 9.0
4-phenyl-3-buten-2-one 8.9
cyclododecanol 8.9
Cupressuflavone 8.9
Jacobine 8.9
1,1-Dichloropropene 8.9
EPNP 8.6
3-amino-2,4,6-triiodobenzoic acid 8.5
C16H11NO4 8.5
C16H11NO4 8.5
C7H9N 8.5
2,3-diphenyloxirane 8.5
C16H11NO4 8.5
C16H11NO4 8.5
Preforan 8.5
C16H11NO4 8.5
Kokusaginine 8.5
C16H11NO4 8.5
C16H11NO4 8.5
Gum karaya 8.5
C16H11NO4 8.1
2-chloroethyl methanesulfonate 8.1
C16H11NO4 8.1
C10H12O2 8.1
Rubiadin 8.1
Disperse Red 11 8.1
C16H11NO4 8.1
10-Deacetylbaccatin III 8.1
Oltipraz 8.1
o-Toluidine 8.0
Uniblue A 7.9
1-iodohexane 7.9
Trichloropropene oxide 7.9
Cyanidin 3-O-beta-D-glucoside 7.8
DHS-I 7.7
C16H11NO4 7.7
Mepenzolate 7.7
Thiamine triphosphate 7.7
Propazine 7.7
dimethyl hydrogen phosphite 7.7
Thiamine triphosphate 7.7
2,2-dimethylpentanoic acid 7.7
Hexabromobenzene 7.7
Tral 7.6
Ethacrynic acid 7.6
8-Hydroxyguanine 7.5
Bitertanol 7.5
ethyl fluoroacetate 7.5
Trichloroisocyanuric acid 7.5
pregn-5-ene-3,20-dione 7.5
C7H14 7.5
11(R)-HETE 7.5
trioxilin A3 7.5
Disperse Blue 3 7.5
Fenpyroximate 7.5
1-bromo-2-chloroethane 7.4
2-nonenoic acid 7.3
DL-alpha-Lipoic acid 7.3
Phorone 7.3
2,4,6-Trichloroanisole 7.3
Tebufenpyrad 7.3
Benalaxyl 7.3
more...