Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:2.5.1.18 (
glutathione S-transferase
)
22,582
document(s) hit in 31,850,051 MEDLINE articles (0.02 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
glutathione S-transferase
13304
GST
9466
GSH
2583
catalase
2103
glutathione peroxidase
1912
superoxide dismutase
1723
Mol
1722
glutathione transferase
1648
Sep
1597
glutathione reductase
1274
fused
889
SOD
872
cytochrome P450
754
microsomal
692
GSTM1
631
xenobiotic
629
CAT
614
GSTT1
527
SDS
427
GSTP1
422
cytochrome P-450
400
acetylcholinesterase
388
polypeptide
378
peroxidase
370
ATP
368
p53
365
antioxidant enzyme
351
P450
314
cytochrome
298
CYP1A1
278
insulin
266
lactate dehydrogenase
254
NADPH
252
thrombin
241
epoxide hydrolase
240
ubiquitin
236
reductase
234
aspartate aminotransferase
233
ATPase
229
GTP
224
Glutathione S-transferase
223
endoplasmic reticulum
217
Nrf2
215
ROS
215
caspase-3
214
DT-diaphorase
213
alkaline phosphatase
205
alanine aminotransferase
204
interacting protein
198
threonine
193
dimeric
190
phosphatase
188
metallothionein
181
cytokine
181
quinone reductase
178
albumin
174
NAD
174
NQO1
166
P-glycoprotein
164
tyrosine kinase
162
Bcl-2
158
esterase
158
CYP2E1
157
NMR
157
thioredoxin
156
heme oxygenase-1
155
gamma-glutamyl transpeptidase
154
erythroid
153
TNF
149
GTPase
148
glucose-6-phosphate dehydrogenase
148
calmodulin
145
UDP-glucuronosyltransferase
144
proliferating cell nuclear antigen
143
glycoprotein
142
tumor necrosis factor
137
AST
136
p38
135
c-Jun
133
p21
131
Catalase
130
microsomal epoxide hydrolase
129
carboxylesterase
128
HSP70
128
Gen
128
membrane protein
125
AChE
124
proteasome
123
CYP1A2
116
Rho
115
JNK
115
1A1
115
histone
114
proline-rich
112
collagen
112
TOF
111
MAPK
111
CYP
111
estrogen receptor
110
carp
110
LPO
110
heat shock protein
107
IL-6
105
membrane-bound
105
gut
104
AP-1
100
Glutathione transferase
100
GSTP1-1
100
NADH
100
DNA-binding domain
95
ERK
95
GDP
94
LDH
93
epidermal growth factor
92
sulfotransferase
92
quinone oxidoreductase
92
CYP3A
92
GSTA1
92
zinc finger
89
aryl hydrocarbon receptor
88
oxidoreductase
87
protein phosphatase
87
hemoglobin
87
aldehyde dehydrogenase
86
UDP-glucuronyltransferase
83
ras
82
cytochrome b5
82
adaptor protein
81
interferon
81
ERK1
81
nuclear receptor
81
aryl hydrocarbon hydroxylase
81
phosphatidylinositol 3-kinase
80
ADP
80
myeloperoxidase
79
glutaredoxin
79
gamma-glutamylcysteine synthetase
79
Pseudomonas
78
p65
77
ligandin
77
MnSOD
76
Superoxide dismutase
76
gamma-glutamyltranspeptidase
75
MDR1
75
P1b
73
methyltransferase
73
lipopolysaccharide
73
phosphoprotein
71
cyclin
71
acid phosphatase
70
inducible nitric oxide synthase
70
Glutathione peroxidase
70
ALP
70
N-acetyltransferase
69
p85
69
CYP2D6
68
MBP
68
glutathione S-transferase pi
68
PKC
68
HEK
68
more...
Disease
GSH
2585
cancer
2291
tumor
1277
carcinogenesis
1040
SDS
427
hepatocellular carcinoma
381
breast cancer
354
carcinoma
292
tumorigenesis
220
lung cancer
215
leukemia
162
diabetes
158
prostate cancer
148
adenocarcinoma
141
Schistosoma japonicum
138
MCF
128
worms
119
HIV
116
colorectal cancer
112
Alzheimer's disease
112
Schistosoma mansoni
109
melanoma
101
malaria
97
cold
95
liver cancer
92
gastric cancer
88
colon cancer
88
squamous cell carcinoma
86
ischemia
85
herpes simplex
83
hepatitis B
83
tumor growth
81
virus infection
77
immunodeficiency
75
schistosomiasis
73
liver cancer
73
bladder cancer
71
Epstein
69
chemical carcinogenesis
69
Parkinson's disease
69
hepatitis C
67
retinoblastoma
67
depression
65
glioma
65
asthma
64
obesity
62
ovarian cancer
62
tumor progression
61
cirrhosis
61
hypertension
58
lymphoma
56
hepatitis
55
neuroblastoma
53
atherosclerosis
52
adenoma
50
influenza
49
liver disease
48
cytomegalovirus
48
acute lymphoblastic leukemia
46
tuberculosis
45
AIN
43
infectious diseases
43
acute myeloid leukemia
43
non-small cell lung cancer
41
chronic hepatitis
41
metastases
40
dengue
40
DDP
40
renal cell carcinoma
39
epithelial ovarian cancer
38
cardiovascular disease
38
cervical cancer
38
AIDS
36
epididymis
36
HSP
36
Mycobacterium
35
vaccinia
34
hyperglycemia
33
uterus
33
lung carcinoma
33
Echinococcus
32
liver fibrosis
31
Farber
31
multiple myeloma
31
rheumatoid arthritis
30
B-cell lymphoma
29
renal disease
27
stroke
26
chronic obstructive pulmonary disease
26
osteosarcoma
26
Evans
26
dysplasia
25
Yersinia
25
West
25
type 2 diabetes
25
oral cancer
25
pertussis
25
SARS
25
pheochromocytoma
25
Infection
24
fatty liver
24
ATM
24
mammary tumor
24
neoplastic transformation
24
arthritis
24
Kaposi's sarcoma
24
malnutrition
23
small cell lung cancer
23
skin cancer
23
aggressiveness
23
chronic myeloid leukemia
23
anemia
23
male infertility
22
glioblastoma
22
plaque
22
Proteus
22
SEM
22
volvulus
22
DBA
22
infertility
21
cognitive impairment
21
cholera
21
myocardial infarction
21
PAL
21
polycystic kidney
20
plague
20
head and neck cancer
20
dehydration
20
ARF
20
parasitic disease
20
amyotrophic lateral sclerosis
20
cornea
19
basal cell carcinoma
19
Huntington's disease
19
systemic lupus erythematosus
19
acute promyelocytic leukemia
19
schizophrenia
19
NS3
19
solid tumor
19
CHS
19
esophageal cancer
19
immunotoxicity
18
cerebral ischemia
18
TEM
18
erythroleukemia
18
APC
18
Chlamydia
18
myeloid leukemia
18
infestation
18
Mycoplasma
18
cholestasis
17
ash
17
ACP
17
esophageal cancer
17
pancreatic cancer
17
multiple sclerosis
17
pneumonia
17
coronary artery disease
16
Brown
16
inflammatory bowel disease
16
more...
Symptom
starvation
62
diarrhea
37
anesthesia
35
pain
26
seizures
25
collapse
15
hyperoxia
12
fatigue
9
hepatomegaly
9
exhaustion
8
vomiting
5
nausea
5
headache
5
polyuria
4
angina
4
hypothermia
4
acute stress
4
respiratory distress
4
anorexia
4
emaciation
3
memory loss
3
ataxia
3
tremor
3
erythema
2
wheezing
2
tense
2
analgesia
2
dizziness
2
stigma
2
Hudson
2
insomnia
2
arthralgia
2
discomfort
2
cachexia
2
hypotonia
2
hypercapnia
2
polydipsia
2
Spots
2
splenomegaly
2
Welt
2
cough
2
abdominal cramps
2
discomfort
2
thinning
2
acidity
2
dry eye
1
DNA marker
1
dystonia
1
hunger
1
masculinization
1
overweight
1
rundown
1
upset stomach
1
weakness
1
skin irritation
1
wrist pain
1
despair
1
Scratch
1
physical appearance
1
flushing
1
microbial colonization
1
loin pain
1
functional recovery
1
persistent cough
1
acute abdomen
1
bitter taste
1
Neuropathic pain
1
syncope
1
tingling
1
hypoproteinemia
1
chest pain
1
abdominal pain
1
nausea and vomiting
1
partial seizure
1
apathy
1
constipation
1
Fluctuation
1
Wind
1
Anoxia
1
knee pain
1
exertional dyspnea
1
menopausal symptoms
1
HSA
1
chills
1
autodigestion
1
acute abdominal pain
1
Halo
1
incoordination
1
Drug
Glutathione
582
ascorbate
221
ROS
215
lysine
170
vitamin E
158
Gel
89
NADH
83
caffeine
48
Mutagen
45
Adriamycin
45
Asn
44
PCB
43
Vitamin E
42
DNase I
40
ABC
39
IL-2
36
IFN-gamma
36
Dermatol
34
Ethanol
30
Monit
27
ALA
25
Leaf
25
MAP
24
CTX
23
Alanine
23
nitroglycerin
22
ZnO
18
lactose
18
ETS
17
FAD
15
CSF
14
EE2
13
Cardiovasc
13
HCH
13
Albumin
13
Taxol
12
Nephron
12
TAC
11
ADR
11
Arsenic trioxide
11
RFP
11
EPA
11
Cibacron Blue
10
Triclosan
9
CTX
9
G418
9
Indomethacin
9
CTX
9
TAT
9
TiO2
9
Capsicum
9
Oxaliplatin
8
NAG
8
p75
8
Retinoic acid
8
CoCl2
8
CoCl2
8
THF
7
Tannic acid
7
Nitric Oxide
7
VCR
7
ADM
7
VCR
7
citric acid
7
ICI
7
Clofibrate
7
Aloe
7
Bifidobacterium
7
ampicillin
6
Cimetidine
6
Vitamin K
6
Rutin
6
Portal
6
AMC
6
Nephron
6
Paraffin
6
Auranofin
6
Asthma
6
ROC
6
Vitamin A
6
PCP
6
CPT-11
5
Spectrum
5
uPA
5
Kenyan
5
Glycyrrhiza
5
Furan
5
Ginger
5
Carotenoid
5
R1881
5
Estrogens
5
Propofol
5
pyridoxal phosphate
5
CDP
5
Angiotensin II
5
Itraconazole
5
Ginseng
5
MRC
5
Spectrum
4
Abamectin
4
Fluorescein
4
Forskolin
4
Fipronil
4
OTC
4
ETA
4
Isoniazid
4
Myricetin
4
Parkin
4
Areca
4
ZnCl2
4
Cimetidine
4
Parkin
4
ZnCl2
4
Fructose
4
Atrovent
4
Rituximab
4
Heme
4
Fraction
4
Biopolymers
4
IFN-beta
4
PTH
4
IL-1ra
4
NBT
3
CPR
3
DHT
3
Honey
3
AHF
3
Simvastatin
3
Fluorescein
3
GRF
3
Tocopherol
3
balanced salt solution
3
Ketoconazole
3
Indocyanine green
3
L-tyrosine
3
ACT
3
CTA
3
BCG vaccine
3
Lead acetate
3
BH4
3
Omeprazole
3
DHT
3
Bezafibrate
3
CaCl2
3
S-Hexylglutathione
3
Sorafenib
3
NH3
3
Nipradilol
3
CaCl2
3
CaCl2
3
Histamine
2
TEL
2
Atenolol
2
Growth hormone
2
Acacia
2
AGG
2
Limonene
2
PPA
2
Iron dextran
2
Fenbendazole
2
more...
Enzyme
glutathione S-transferase
22582
catalase
2547
superoxide dismutase
2333
glutathione peroxidase
1962
glutathione reductase
1266
NQO1
507
mitogen-activated protein kinase
474
peroxidase
468
acetylcholinesterase
443
protein kinase
437
alanine aminotransferase
414
aspartate aminotransferase
366
gamma-glutamyl transpeptidase
339
UDP-glucuronosyltransferase
297
ATPase
268
lactate dehydrogenase
260
soluble epoxide hydrolase
248
thrombin
230
luciferase
229
glucose-6-phosphate dehydrogenase
211
ERK
208
alkaline phosphatase
205
demethylase
205
protein kinase C
197
P-glycoprotein
167
caspase-3
156
microsomal epoxide hydrolase
151
AST
135
ascorbate peroxidase
133
calcineurin
131
CPR
131
trypsin
130
carboxylesterase
130
proteasome
130
focal adhesion kinase
127
RNA polymerase
114
cholinesterase
111
gamma-glutamylcysteine synthetase
105
aryl hydrocarbon hydroxylase
97
aldehyde dehydrogenase
92
MEK
91
aldehyde dehydrogenase
91
aldehyde dehydrogenase
90
aldehyde dehydrogenase
86
aldehyde dehydrogenase
86
peroxiredoxin
84
topoisomerase
81
phosphatidylinositol 3-kinase
81
reverse transcriptase
78
cdc2
74
N-acetyltransferase
72
topoisomerase
70
acid phosphatase
70
heme oxygenase
69
diaphorase
66
thioredoxin reductase
61
glyceraldehyde-3-phosphate dehydrogenase
61
alcohol dehydrogenase
61
dehydroascorbate reductase
58
lysozyme
58
glyceraldehyde-3-phosphate dehydrogenase
55
xanthine oxidase
55
AMPK
55
CYP3A4
54
phospholipase C
54
PARP
53
RNase
52
PAH
51
lipoxygenase
51
beta-galactosidase
47
creatine kinase
47
ornithine decarboxylase
46
chloramphenicol acetyltransferase
46
glyceraldehyde-3-phosphate dehydrogenase
44
glyceraldehyde-3-phosphate dehydrogenase
44
glyceraldehyde-3-phosphate dehydrogenase
44
DNA polymerase
44
RNase
43
IKK
42
AMP-activated protein kinase
40
pyruvate kinase
39
transcriptase
39
MDR
38
ATP synthase
37
collagenase
37
thymidylate synthase
37
protein phosphatase 2A
36
complex I
35
enolase
35
PAL
35
lipase
34
beta-glucuronidase
34
chymotrypsin
32
NADPH oxidase
32
papain
32
NADPH oxidase
32
monoamine oxidase
31
ACE
31
aldose reductase
30
glutathione synthetase
30
cysteine synthase
30
malate dehydrogenase
29
aldolase
29
sorbitol dehydrogenase
29
caspase-9
29
SOR
28
glutamine synthetase
27
NO synthase
27
MAP
26
succinate dehydrogenase
26
phospholipase A2
26
caspase-8
26
phosphoinositide 3-kinase
25
glyoxalase II
25
thromboplastin
24
ACS
24
enterokinase
24
kinesin
24
carbonic anhydrase
24
chalcone synthase
24
DNA methyltransferase
24
APC
23
PST
23
NOS
23
glutamate dehydrogenase
22
glutamate dehydrogenase
22
glutamate dehydrogenase
22
tyrosinase
22
cathepsin L
21
transpeptidase
21
GSK
21
NADH-cytochrome b5 reductase
21
phosphodiesterase
21
phospholipase D
21
endonuclease
21
paraoxonase
21
pyruvate dehydrogenase
21
dihydrofolate reductase
21
LTC4 synthase
21
PAL
21
delta-aminolevulinic acid dehydratase
21
paraoxonase
20
histone acetyltransferase
20
cathepsin B
20
MEKK1
19
AMPK
19
6-phosphogluconate dehydrogenase
19
6-phosphogluconate dehydrogenase
19
sulfatase
19
transglutaminase
19
ceruloplasmin
19
citrate synthase
19
ECH
19
phosphorylase
19
PDK1
18
glucose-6-phosphatase
18
cathepsin D
18
methylenetetrahydrofolate reductase
18
methylenetetrahydrofolate reductase
18
neuraminidase
18
more...
Compound
GSH
3003
GSH
3003
DNA
2938
Dec
1649
oxygen
1131
water
1052
1-chloro-2,4-dinitrobenzene
871
tyrosine
699
CAT
616
CAT
614
CAT
614
cysteine
579
calcium
468
sodium
464
SDS
444
His
431
pyrene
429
serine
413
hydrogen
407
alanine
406
ATP
368
glucose
355
arginine
333
Clin
333
threonine
312
GSSG
306
phosphate
300
MDA
299
selenium
293
lysine
276
zinc
276
cadmium
269
urea
260
NADPH
252
NADPH
252
copper
243
nitric oxide
238
acetate
232
GTP
228
H2O2
223
ethanol
222
sulfate
219
methionine
212
aflatoxin B1
207
UDP
193
nitrogen
191
iron
188
NAD
186
COS
182
creatinine
181
Phe
179
leucine
177
NAD
174
salt
173
Ile
155
proline
153
TNF
149
anthracene
146
Gly
138
Asp
123
cAMP
120
tryptophan
114
glutamate
112
TOF
111
MTT
110
DEN
108
aniline
106
N-acetylcysteine
98
NH2
96
galactose
96
tryptophan
96
retinoic acid
94
tryptophan
94
tryptophan
94
GDP
94
CCl4
91
ADP
85
silver
84
aldehyde
84
NADH
83
potassium
83
8-OHdG
82
mercury
82
manganese
82
ADP
80
bromide
80
ADP
80
DDP
75
benzene
75
uridine
74
nitrate
72
Pac
72
glutamine
70
ALP
70
aldehyde
69
ammonium
69
DDT
68
salicylic acid
67
dichloromethane
63
AMP
62
nickel
62
Triton X-100
61
PEG
60
methanol
60
pyridine
58
APAP
58
Adriamycin
58
Curcumin
56
DBA
55
naphthalene
55
valine
55
EDTA
53
EDTA
52
PMA
52
AAF
52
PAH
51
DEAE
50
phenol
50
Insulin
50
MEK
50
Malondialdehyde
50
2-nonenal
49
Luminal
49
NTA
49
chromium
49
caffeine
48
DMSO
48
CoA
48
alcohol dehydrogenase
48
Vitamin E
48
Mg2+
47
1,2-dimethylhydrazine
46
formaldehyde
45
quinoline
42
acrylamide
42
acetone
42
quinoline
42
NADP
41
phenanthrene
41
Arsenic
41
isoleucine
41
acetic acid
41
glycerol
41
PEG
40
isoleucine
40
nicotinamide
40
glutamic acid
40
Ascorbic acid
40
iodine
40
LTC4
39
ammonia
39
Cyt
39
MDR
39
formaldehyde
37
indole-3-carbinol
37
1-naphthol
37
CdCl2
37
aluminum
36
Tyrosine
35
aspartic acid
34
more...