Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:2.4.99.6 (sialyltransferase)
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Human Gene/Protein
sialyltransferase 1533
CMP 335
Gal 207
glycoprotein 195
galactosyltransferase 150
beta 1 148
lectin 140
Sep 108
glycosyltransferase 104
alpha2,6-sialyltransferase 93
sialidase 92
fucosyltransferase 91
neuraminidase 87
ST6Gal I 77
Mol 70
mucin 60
ST3Gal I 52
endoplasmic reticulum 38
NMR 38
membrane-bound 37
alpha 2,6-sialyltransferase 35
SIAT1 35
polypeptide 32
STZ 31
microsomal 29
N-acetylglucosaminyltransferase 26
GD3 synthase 25
alpha 2,3-sialyltransferase 25
CMP-sialic acid synthetase 22
lipopolysaccharide 22
N-acetylgalactosaminyltransferase 22
GM3 synthase 20
CDP 20
neural cell adhesion molecule 19
ST6GAL1 18
glucosamine 18
ST3Gal III 18
E-selectin 17
transferrin 17
MUC1 17
UDP-GlcNAc 17
alpha2,3-sialyltransferase 17
SDS 16
GalNAcT 16
fibronectin 14
ISH 14
membrane protein 14
thymus 14
ST3GAL4 13
ATP 13
Neuraminidase 12
albumin 12
CD22 12
fused 12
alkaline phosphatase 12
CD45 11
ST3 11
GDP 11
UDP-GalNAc 11
cage 11
beta-galactoside alpha-2,6-sialyltransferase 11
CD56 11
STX 11
CD82 11
erythropoietin 10
SAT 10
lymphoid 10
GalT 10
N-acetylglucosaminyltransferase I 10
cytokine 10
insulin 10
ST3Gal II 10
SNA 10
Galactosyltransferase 10
ST6GALNAC2 9
colon carcinoma 9
CTP 9
ST8Sia III 9
Glycosyltransferase 9
CD8 9
galactosamine 8
ST6GalNAc III 8
alpha1-acid glycoprotein 8
CD4 8
N-CAM 8
beta-1,4-galactosyltransferase 8
GD3S 8
ST6GalNAc I 8
ST3GAL3 8
threonine 8
serum albumin 8
type II membrane protein 8
ST3GAL5 8
caspase-3 7
NEU2 7
TLR4 7
HEK 7
transferrin receptor 7
epidermal growth factor receptor 7
CMP-sialic acid transporter 7
pyrophosphatase 7
collagen 7
BACE1 7
ST8Sia IV 7
castor 7
alpha-L-fucosidase 7
carcinoembryonic antigen 7
CD43 7
PST 7
UDP-N-acetylglucosamine 6
TOF 6
glucosyltransferase 6
IL-4 6
p38 6
ATPase 6
spermatozoa 6
interferon 6
dimeric 6
TNF 6
epidermal growth factor 6
acid phosphatase 6
P-selectin 6
glucosylceramide synthase 6
N-acetylglucosaminyltransferase V 6
sulfotransferase 6
O-acetyltransferase 6
alpha2,8-sialyltransferase 6
ERK 6
cathepsin D 6
membrane glycoprotein 6
extracellular signal-regulated kinase 5
amyloid precursor protein 5
sialic acid synthase 5
ST3N 5
IgA 5
tumor-associated antigen 5
transmembrane protein 5
CD15 5
glycophorin A 5
long chain 5
histone 5
galectin-1 5
ST8Sia VI 5
ST8Sia II 5
nodal 5
TGN 5
IL-6 5
ST6Gal II 5
ST3GAL6 5
galectin-3 5
brush border 5
ST6GALNAC5 5
5'-nucleotidase 5
H. influenzae 5
MAPK 5
IFN 5
mTOR 4
glucosaminyl 4
RACE 4
PHA 4
more...
Disease
cancer 183
tumor 143
breast cancer 42
carcinoma 41
hepatocellular carcinoma 36
melanoma 31
colon cancer 29
influenza 29
metastases 27
tumor progression 26
neuroblastoma 20
tumorigenesis 18
leukemia 17
adenocarcinoma 16
SDS 16
Haemophilus 15
gonococcal 14
multiple myeloma 14
ISH 14
ovarian cancer 14
MCF 13
colorectal cancer 13
virus infection 12
Alzheimer's disease 11
ST3 11
carcinogenesis 11
glioma 11
cholera 11
tumor growth 9
chancroid 9
mimicry 9
cystic fibrosis 9
prostate cancer 9
diabetes 9
chronic myeloid leukemia 8
sepsis 8
pancreatic cancer 8
meningitis 8
lung cancer 7
sepsis 7
gastric cancer 7
depression 6
erythroleukemia 6
Newcastle disease 6
epilepsy 6
lymphoma 6
acute lymphoblastic leukemia 5
bladder cancer 5
autoimmune disease 5
acute myeloid leukemia 5
lung carcinoma 5
neuropathy 5
mammary tumor 4
lymphoblastic leukemia 4
primary tumor 4
enteritis 4
B-cell lymphoma 4
cardiomyopathy 4
PHA 4
stomatitis 4
obesity 4
renal disease 4
PSA 4
cervical cancer 4
atherosclerosis 4
proteinuria 4
epididymis 4
squamous cell carcinoma 4
epithelial ovarian cancer 4
chronic lymphocytic leukemia 3
gastroenteritis 3
parvovirus 3
liver metastases 3
renal cell carcinoma 3
metastatic breast cancer 3
Gilbert 3
infertility 3
chronic lymphocytic leukemia 3
systemic lupus erythematosus 3
Epstein 3
complex partial seizures 3
mole 3
chronic bronchitis 3
alcohol abuse 3
schizophrenia 3
aggressiveness 3
goiter 3
tumor angiogenesis 3
hepatoblastoma 3
Down syndrome 3
neoplastic transformation 3
Thomsen 3
rheumatoid arthritis 3
IgA nephropathy 3
thrombocytopenia 3
uterus 3
mole 3
lung metastases 3
bacteremia 2
immunodeficiency 2
SCID 2
bacterial meningitis 2
lupus 2
deafness 2
AIDS 2
thyroid cancer 2
Colon 2
brain metastases 2
astrocytoma 2
colitis 2
hepatitis B 2
coronary artery disease 2
failure to thrive 2
lupus 2
Ovary 2
pneumonia 2
Neuroblastoma 2
fibrosarcoma 2
arthritis 2
Colon 2
choriocarcinoma 2
hypertension 2
ST8 2
CAM 2
blast crisis 2
worms 2
encephalitis 2
hyperglycemia 2
infectious diseases 2
Leukemia 2
heart disease 2
liver cancer 2
avian influenza 2
cirrhosis 2
PSS 2
Blocking 2
fatty liver 2
Ovary 2
Colon 2
liver disease 2
adenoma 2
metastatic melanoma 2
Roth 2
choreoathetosis 2
T-cell lymphoma 2
meningioma 2
Malignant transformation 2
vaccinia 2
hypothyroidism 2
polyarthritis 2
Melanoma 2
solid tumor 2
glioblastoma 2
ichthyosis 2
conjunctiva 2
heart failure 2
Miller Fisher syndrome 2
embryonal carcinoma 2
ichthyosis 2
dilated cardiomyopathy 2
more...
Symptom
seizures 6
ophthalmoplegia 4
acidity 3
ataxia 3
starvation 2
collapse 2
weakness 2
acute stress 1
hepatomegaly 1
hypotonia 1
Ill 1
diarrhea 1
impaired motor coordination 1
cachexia 1
pain 1
fasciculation 1
Drug
lactose 42
CDP 20
Asn 13
Cytidine 6
Dermatol 5
Retinoic acid 5
CSF 5
Ganciclovir 4
Gel 4
IL-2 3
Pronase 3
lysine 3
NADH 3
Cibacron Blue 3
CAM 2
Bifidobacterium 2
NAG 2
IFN-gamma 2
Leaf 2
RFP 2
EE2 2
Thyroglobulin 2
GNA 2
Lactose 2
ADR 1
Cardiovasc 1
Oseltamivir 1
Hypaque 1
Adriamycin 1
ACT 1
Relenza 1
AZT 1
Camp 1
RbCl 1
Hypaque 1
Galactose 1
Fraction 1
Fluorescein 1
Silica 1
RbCl 1
balanced salt solution 1
PE2 1
G-CSF 1
ROS 1
-deoxyadenosine 1
MAP 1
Herceptin 1
MRC 1
Bortezomib 1
AZT 1
p75 1
citric acid 1
Monensin 1
G418 1
Ethanol 1
CPM 1
Iodixanol 1
Fluorescein 1
Enzyme
sialyltransferase 1546
sialyltransferase 1533
sialyltransferase 1533
neuraminidase 177
sialidase 92
EC 2.4.99.1 63
GD3 synthase 28
N-acetylglucosaminyltransferase 26
GM3 synthase 23
beta-galactosidase 22
mitogen-activated protein kinase 17
ERK 16
CMP-Neu5Ac synthetase 16
protein kinase C 14
trypsin 13
GalT 13
alkaline phosphatase 12
EC 2.4.99.4 10
beta-1,4-galactosyltransferase 10
N-acetylglucosaminyltransferase I 10
luciferase 8
mannosidase II 8
FucT 7
endoglycosidase H 7
peroxidase 7
NPL 7
PNGase F 7
PST 7
hexosaminidase 6
cathepsin D 6
glucosylceramide synthase 6
N-acetylglucosaminyltransferase V 6
ATPase 6
alpha-L-fucosidase 6
acid phosphatase 6
tissue plasminogen activator 5
lactose synthetase 5
focal adhesion kinase 5
endo-beta-galactosidase 5
mannosidase I 5
endo-beta-galactosidase 5
5'-nucleotidase 5
ricin 5
alpha-L-fucosidase 4
alpha-L-fucosidase 4
calcineurin 4
S1 nuclease 4
N-acetylgalactosaminyltransferase I 4
alpha-mannosidase 4
protein kinase 4
acetylesterase 4
phosphodiesterase 4
CMP-sialic acid:lactosylceramide sialyltransferase 4
reverse transcriptase 4
galactose oxidase 4
caspase-3 3
endo-N 3
beta-secretase 3
chloramphenicol acetyltransferase 3
lysozyme 3
ACS 3
CMP-sialic acid hydrolase 3
alpha-galactosidase 3
GalNAc-T 3
aldolase 3
PARP 3
N-acetylglucosaminyltransferase III 3
CMP-Neu5Ac hydroxylase 3
acetylcholinesterase 3
plasmin 3
phosphorylase 2
NeuAc synthase 2
ADPase 2
transglutaminase 2
EC 2.4.1.65 2
invertase 2
P-glycoprotein 2
sphingomyelin synthase 2
CPR 2
RNase 2
urokinase-type plasminogen activator 2
catalase 2
alcohol dehydrogenase 2
pyruvate kinase 2
glucose-6-phosphatase 2
phospholipase C 2
neutrophil elastase 2
thrombin 2
EC 2.4.99.3 2
galactokinase 2
ribonuclease 2
galactosyltransferase I 2
N-acetylglucosaminyltransferase IV 2
dipeptidyl peptidase IV 2
glutathione S-transferase 2
EC 2.4.1.102 2
RNase 2
proteinase K 2
collagenase 2
polypeptide N-acetylgalactosaminyltransferase 2
caspase-8 2
chymotrypsin 2
caspase-9 2
MEK 2
dihydrofolate reductase 2
ceruloplasmin 2
CDH 2
ribonuclease 2
acetate kinase 1
lactate dehydrogenase 1
MAT 1
furin 1
ganglioside galactosyltransferase 1
condensing enzyme 1
sialate O-acetyltransferase 1
PRE 1
beta-glucosidase 1
CPM 1
SPC 1
guanylate cyclase 1
glucoamylase 1
beta-glucuronidase 1
hyaluronidase 1
dihydroorotate dehydrogenase 1
polyphosphate kinase 1
NADPH oxidase 1
succinate dehydrogenase 1
complex I 1
diaphorase 1
N-acetylglucosaminyltransferase II 1
branching enzyme 1
NADPH oxidase 1
mannosylphosphoryldolichol synthase 1
alanine aminotransferase 1
GalT-4 1
alpha-galactosyltransferase 1
dihydroorotate dehydrogenase 1
nucleoside diphosphokinase 1
uridyltransferase 1
poly(A) polymerase 1
hyaluronidase 1
neutral sphingomyelinase 1
ADP-ribosyltransferase 1
thyroid peroxidase 1
elastase 1
TdT 1
renin 1
aspartate aminotransferase 1
cholinesterase 1
glucokinase 1
ceramidase 1
papain 1
ADP-ribosyltransferase 1
glutamine synthetase 1
glycerol-3-phosphate dehydrogenase 1
monosialoganglioside sialyltransferase 1
PTPase 1
cellulose synthase 1
DNA methyltransferase 1
GSK 1
more...
Compound
CMP 339
CMP 335
Neu5Ac 167
galactose 166
GlcNAc 114
Dec 111
GM3 95
GalNAc 91
GM1 61
GD3 59
Sialic acid 57
DNA 52
Triton X-100 44
Clin 39
phosphate 39
sodium 36
COS 34
UDP-galactose 31
threonine 29
acetate 26
Lewis X 26
CMP-N-acetylneuraminate 25
GM2 25
CMP-N-acetylneuraminate 25
sulfate 24
UDP-GlcNAc 23
SDS 22
calcium 21
glucose 21
CDP 20
Triton 19
MDA 17
manganese 17
ethanol 17
tyrosine 16
retinoic acid 16
UDP 16
asparagine 16
CDH 16
serine 15
Lea 15
water 15
His 14
N-acetylmannosamine 14
leucine 14
ATP 13
Cer 12
NH2 12
Mg2+ 11
GDP 11
methanol 11
beta-D-galactoside 10
oxygen 10
CTP 10
glycerol 9
methionine 9
D-galactopyranosyl 9
PNA 9
uridine 8
cysteine 8
alanine 7
lysine 7
Cyd 6
EDTA 6
TOF 6
potassium 6
hydrogen 6
aldehyde 6
TNF 6
EDTA 6
iron 6
aldehyde 5
Asp 5
Gly 5
thioglycollate 5
TCA 5
TSH 5
iodine 5
hexose 5
GA1 5
acrylamide 5
UTP 4
Agarose 4
GA2 4
PEG 4
ACS 4
C-3 4
arginine 4
heptose 4
GTP 4
heptose 4
DEAE 4
heptose 4
UDP-glucose 4
DMSO 4
butyric acid 4
chloroform 4
Lac 4
cAMP 4
ammonia 4
Insulin 3
aldosterone 3
hexose 3
Gb4 3
glutamine 3
Neu5,9Ac2 3
AMP 3
Thyroid 3
Phe 3
glutamic acid 3
PEG 3
THP 3
ADR 3
ACS 3
Cardiol 3
NADPH 3
hexose 3
ammonium 3
copper 3
APS 3
ADP 3
hexose 3
zinc 3
ADP 3
Adriamycin 3
THP 3
ADP 3
NADH 3
KDN 3
Ile 3
PMA 3
Tunicamycin 3
NADPH 3
Dexamethasone 3
hyaluronic acid 2
UMP 2
CAM 2
phosphite 2
acrylonitrile 2
Lactose 2
STZ 2
2-aminobenzoic acid 2
Trypsin 2
tryptophan 2
UDP-N-acetylgalactosamine 2
selenium 2
Estradiol 2
2-aminobenzoic acid 2
nitrate 2
xylose 2
Neuronal 2
N-hydroxysuccinimide ester 2
MAL 2
Sucrose 2
Amide 2
PMA 2
GAL 2
N-acetyl-D-glucosamine 2
NeuAcalpha2,6Galbeta1,4GlcNAc 2
PAN 2
more...