Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:2.4.99.10 (sialyltransferase)
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Human Gene/Protein
sialyltransferase 1533
CMP 337
Gal 207
glycoprotein 196
galactosyltransferase 151
beta 1 149
lectin 138
Sep 108
glycosyltransferase 103
alpha2,6-sialyltransferase 95
sialidase 92
fucosyltransferase 91
neuraminidase 88
ST6Gal I 74
Mol 69
mucin 60
ST3Gal I 52
STZ 42
NMR 39
endoplasmic reticulum 38
membrane-bound 37
SIAT1 32
polypeptide 31
alpha 2,6-sialyltransferase 31
microsomal 29
GD3 synthase 25
N-acetylglucosaminyltransferase 25
alpha 2,3-sialyltransferase 24
CMP-sialic acid synthetase 22
N-acetylgalactosaminyltransferase 22
lipopolysaccharide 22
CDP 20
GM3 synthase 20
UDP-GlcNAc 19
neural cell adhesion molecule 19
ST6GAL1 18
glucosamine 18
GalNAcT 17
E-selectin 17
transferrin 17
ST3Gal III 17
MUC1 17
alpha2,3-sialyltransferase 17
SDS 16
fibronectin 14
membrane protein 14
ISH 14
thymus 14
SAT 13
ATP 13
ST3GAL4 13
fused 13
GDP 13
Neuraminidase 13
albumin 12
alkaline phosphatase 12
UDP-GalNAc 12
CD22 12
SAT-1 12
colon carcinoma 11
CD45 11
CD82 11
STX 11
ST3 11
cage 11
CD56 11
beta-galactoside alpha-2,6-sialyltransferase 11
erythropoietin 10
SNA 10
GalT 10
N-acetylglucosaminyltransferase I 10
cytokine 10
insulin 10
Galactosyltransferase 10
ST6GALNAC2 9
lymphoid 9
CTP 9
Glycosyltransferase 9
ST8Sia III 9
ST3Gal II 9
CD8 9
galactosamine 8
serum albumin 8
beta-1,4-galactosyltransferase 8
N-CAM 8
caspase-3 8
ST3GAL5 8
CD4 8
alpha1-acid glycoprotein 8
ST3GAL3 8
ST6GalNAc III 8
ST6GalNAc I 8
GD3S 8
threonine 8
type II membrane protein 8
carcinoembryonic antigen 8
TOF 7
NEU2 7
TLR4 7
alpha-L-fucosidase 7
HEK 7
transferrin receptor 7
epidermal growth factor receptor 7
CMP-sialic acid transporter 7
BACE1 7
collagen 7
pyrophosphatase 7
PST 7
ST8Sia IV 7
castor 7
CD43 7
UDP-N-acetylglucosamine 6
IL-4 6
glucosyltransferase 6
p38 6
spermatozoa 6
ATPase 6
interferon 6
dimeric 6
P-selectin 6
acid phosphatase 6
glucosylceramide synthase 6
TNF 6
epidermal growth factor 6
N-acetylglucosaminyltransferase V 6
sulfotransferase 6
O-acetyltransferase 6
alpha2,8-sialyltransferase 6
ERK 6
membrane glycoprotein 6
cathepsin D 6
IFN 5
extracellular signal-regulated kinase 5
amyloid precursor protein 5
sialic acid synthase 5
IgA 5
tumor-associated antigen 5
ST3N 5
H. influenzae 5
transmembrane protein 5
glycophorin A 5
CD15 5
galectin-1 5
long chain 5
ST8Sia VI 5
ST8Sia II 5
histone 5
brush border 5
nodal 5
TGN 5
ST6Gal II 5
IL-6 5
5'-nucleotidase 5
ST3GAL6 5
galectin-3 5
MAPK 5
ST6GALNAC5 5
von Willebrand factor 4
glucosaminyl 4
PHA 4
more...
Disease
cancer 184
tumor 142
breast cancer 43
carcinoma 41
hepatocellular carcinoma 35
melanoma 30
colon cancer 29
influenza 29
metastases 27
tumor progression 26
neuroblastoma 20
tumorigenesis 19
leukemia 17
adenocarcinoma 16
SDS 16
Haemophilus 15
ISH 14
ovarian cancer 14
gonococcal 14
multiple myeloma 14
MCF 14
colorectal cancer 13
virus infection 12
carcinogenesis 11
glioma 11
cholera 11
Alzheimer's disease 11
ST3 11
mimicry 9
cystic fibrosis 9
tumor growth 9
diabetes 9
prostate cancer 9
chancroid 9
meningitis 8
chronic myeloid leukemia 8
pancreatic cancer 8
sepsis 8
lung cancer 7
gastric cancer 7
lymphoma 7
sepsis 7
erythroleukemia 6
epilepsy 6
Newcastle disease 6
depression 6
acute myeloid leukemia 5
autoimmune disease 5
acute lymphoblastic leukemia 5
bladder cancer 5
lung carcinoma 5
neuropathy 5
obesity 4
epithelial ovarian cancer 4
PSA 4
atherosclerosis 4
B-cell lymphoma 4
epididymis 4
cardiomyopathy 4
PHA 4
stomatitis 4
proteinuria 4
cervical cancer 4
Foot-and-mouth disease 4
mammary tumor 4
renal disease 4
enteritis 4
squamous cell carcinoma 4
lymphoblastic leukemia 4
primary tumor 4
chronic lymphocytic leukemia 3
gastroenteritis 3
thrombocytopenia 3
parvovirus 3
chronic lymphocytic leukemia 3
rheumatoid arthritis 3
Gilbert 3
mole 3
uterus 3
infertility 3
complex partial seizures 3
systemic lupus erythematosus 3
chronic bronchitis 3
mole 3
ST8 3
alcohol abuse 3
schizophrenia 3
mouth disease 3
aggressiveness 3
tumor angiogenesis 3
liver metastases 3
goiter 3
hepatoblastoma 3
Down syndrome 3
IgA nephropathy 3
renal cell carcinoma 3
Thomsen 3
neoplastic transformation 3
lung metastases 3
metastatic breast cancer 3
ichthyosis 2
SCID 2
infectious diseases 2
bacterial meningitis 2
immunodeficiency 2
lupus 2
bacteremia 2
Colon 2
deafness 2
thyroid cancer 2
astrocytoma 2
colitis 2
brain metastases 2
coronary artery disease 2
hepatitis B 2
failure to thrive 2
arthritis 2
Colon 2
Ovary 2
lupus 2
fibrosarcoma 2
embryonal carcinoma 2
Epstein 2
Colon 2
choriocarcinoma 2
worms 2
hypertension 2
heart failure 2
Neuroblastoma 2
encephalitis 2
CAM 2
blast crisis 2
hyperglycemia 2
Leukemia 2
liver cancer 2
avian influenza 2
cirrhosis 2
AIDS 2
fatty liver 2
PSS 2
T-cell lymphoma 2
metastatic melanoma 2
liver disease 2
Blocking 2
Miller Fisher syndrome 2
adenoma 2
Ovary 2
meningioma 2
choreoathetosis 2
Roth 2
Malignant transformation 2
vaccinia 2
glioblastoma 2
hypothyroidism 2
polyarthritis 2
Melanoma 2
dilated cardiomyopathy 2
heart disease 2
ichthyosis 2
solid tumor 2
more...
Symptom
seizures 6
ophthalmoplegia 4
acidity 3
ataxia 3
starvation 2
collapse 2
weakness 2
acute stress 1
hepatomegaly 1
hypotonia 1
Ill 1
diarrhea 1
impaired motor coordination 1
cachexia 1
pain 1
fasciculation 1
Drug
lactose 41
CDP 20
Asn 13
Cytidine 6
CSF 5
Retinoic acid 5
Dermatol 5
Ganciclovir 4
Gel 4
Cibacron Blue 3
lysine 3
Pronase 3
NADH 3
IL-2 3
CAM 2
Bifidobacterium 2
NAG 2
RFP 2
EE2 2
Thyroglobulin 2
IFN-gamma 2
GNA 2
Lactose 2
ADR 1
Cardiovasc 1
Oseltamivir 1
Hypaque 1
Adriamycin 1
ACT 1
Relenza 1
Camp 1
RbCl 1
AZT 1
Hypaque 1
Fraction 1
Leaf 1
Fluorescein 1
Silica 1
RbCl 1
balanced salt solution 1
Galactose 1
PE2 1
G-CSF 1
ROS 1
-deoxyadenosine 1
MAP 1
Herceptin 1
MRC 1
Bortezomib 1
AZT 1
p75 1
citric acid 1
Monensin 1
G418 1
Ethanol 1
CPM 1
Iodixanol 1
Fluorescein 1
Enzyme
sialyltransferase 1547
sialyltransferase 1533
sialyltransferase 1533
neuraminidase 178
sialidase 92
EC 2.4.99.1 61
GD3 synthase 35
N-acetylglucosaminyltransferase 25
beta-galactosidase 23
GM3 synthase 23
mitogen-activated protein kinase 17
ERK 16
CMP-Neu5Ac synthetase 16
protein kinase C 14
GalT 14
trypsin 14
alkaline phosphatase 12
N-acetylglucosaminyltransferase I 10
EC 2.4.99.4 10
beta-1,4-galactosyltransferase 10
FucT 9
luciferase 8
mannosidase II 8
peroxidase 7
PNGase F 7
endoglycosidase H 7
PST 7
NPL 7
ATPase 6
alpha-L-fucosidase 6
cathepsin D 6
N-acetylglucosaminyltransferase V 6
hexosaminidase 6
acid phosphatase 6
glucosylceramide synthase 6
ricin 5
focal adhesion kinase 5
endo-beta-galactosidase 5
endo-beta-galactosidase 5
5'-nucleotidase 5
tissue plasminogen activator 5
mannosidase I 5
caspase-3 4
alpha-mannosidase 4
phosphodiesterase 4
S1 nuclease 4
alpha-L-fucosidase 4
lactose synthetase 4
acetylesterase 4
GalT-4 4
calcineurin 4
protein kinase 4
CMP-sialic acid:lactosylceramide sialyltransferase 4
N-acetylgalactosaminyltransferase I 4
galactose oxidase 4
reverse transcriptase 4
alpha-L-fucosidase 4
endo-N 3
alpha-galactosidase 3
acetylcholinesterase 3
chloramphenicol acetyltransferase 3
plasmin 3
CMP-Neu5Ac hydroxylase 3
ACS 3
CMP-sialic acid hydrolase 3
GalNAc-T 3
PARP 3
lysozyme 3
aldolase 3
N-acetylglucosaminyltransferase III 3
EC 2.4.1.102 3
caspase-9 3
beta-secretase 3
sphingomyelin synthase 2
RNase 2
glucose-6-phosphatase 2
ceruloplasmin 2
ribonuclease 2
urokinase-type plasminogen activator 2
NeuAc synthase 2
alcohol dehydrogenase 2
catalase 2
invertase 2
P-glycoprotein 2
CPR 2
neutrophil elastase 2
pyruvate kinase 2
thrombin 2
EC 2.4.99.3 2
galactokinase 2
phospholipase C 2
galactosyltransferase I 2
N-acetylglucosaminyltransferase IV 2
ribonuclease 2
glutathione S-transferase 2
dipeptidyl peptidase IV 2
phosphorylase 2
RNase 2
proteinase K 2
polypeptide N-acetylgalactosaminyltransferase 2
ADPase 2
caspase-8 2
collagenase 2
MEK 2
CDH 2
dihydrofolate reductase 2
caspase-6 1
acetate kinase 1
lactate dehydrogenase 1
MAT 1
furin 1
condensing enzyme 1
sialate O-acetyltransferase 1
beta-glucosidase 1
PRE 1
EC 2.4.1.65 1
guanylate cyclase 1
glucoamylase 1
beta-glucuronidase 1
hyaluronidase 1
neutral sphingomyelinase 1
hyaluronidase 1
N-acetylglucosaminylphosphotransferase 1
polyphosphate kinase 1
proteasome 1
renin 1
NADPH oxidase 1
EC 2.4.1.152 1
aspartate aminotransferase 1
succinate dehydrogenase 1
complex I 1
diaphorase 1
ganglioside galactosyltransferase 1
mannosylphosphoryldolichol synthase 1
NADPH oxidase 1
branching enzyme 1
alpha-galactosyltransferase 1
dihydroorotate dehydrogenase 1
nucleoside diphosphokinase 1
SPC 1
uridyltransferase 1
poly(A) polymerase 1
ADP-ribosyltransferase 1
CPM 1
TdT 1
cholinesterase 1
elastase 1
papain 1
thyroid peroxidase 1
ADP-ribosyltransferase 1
3C protease 1
dihydroorotate dehydrogenase 1
N-acetylglucosaminyltransferase II 1
ceramidase 1
glucokinase 1
glutamine synthetase 1
monosialoganglioside sialyltransferase 1
PTPase 1
glycerol-3-phosphate dehydrogenase 1
cellulose synthase 1
more...
Compound
CMP 341
CMP 337
Neu5Ac 168
galactose 166
GlcNAc 115
Dec 113
GM3 97
GalNAc 92
GM1 61
GD3 58
Sialic acid 57
DNA 51
Triton X-100 43
phosphate 39
Clin 39
sodium 35
UDP-galactose 34
COS 34
threonine 29
Lewis X 28
GM2 27
acetate 26
UDP-GlcNAc 25
sulfate 24
CMP-N-acetylneuraminate 24
CMP-N-acetylneuraminate 24
SDS 22
calcium 21
Triton 20
glucose 20
CDP 20
MDA 18
ethanol 17
manganese 17
tyrosine 16
asparagine 16
retinoic acid 16
CDH 16
serine 15
Lea 15
UDP 15
N-acetylmannosamine 14
His 14
Cer 14
water 14
GDP 13
leucine 13
ATP 13
Mg2+ 11
NH2 11
methanol 11
beta-D-galactoside 10
methionine 10
CTP 10
oxygen 10
glycerol 9
D-galactopyranosyl 9
PNA 9
uridine 8
cysteine 8
TOF 7
alanine 7
lysine 7
EDTA 6
Cyd 6
potassium 6
hydrogen 6
aldehyde 6
TNF 6
iron 6
EDTA 6
aldehyde 5
TSH 5
Asp 5
Gly 5
thioglycollate 5
TCA 5
DEAE 5
hexose 5
GA1 5
Lac 5
iodine 5
acrylamide 5
UTP 4
Agarose 4
ACS 4
C-3 4
GA2 4
arginine 4
heptose 4
GTP 4
heptose 4
heptose 4
UDP-glucose 4
butyric acid 4
DMSO 4
cAMP 4
chloroform 4
ammonia 4
Insulin 3
aldosterone 3
hexose 3
Neu5,9Ac2 3
AMP 3
Thyroid 3
Phe 3
PEG 3
glutamic acid 3
Gb4 3
THP 3
ACS 3
ADR 3
Cardiol 3
NADPH 3
hexose 3
copper 3
hexose 3
ADP 3
ammonium 3
zinc 3
Adriamycin 3
ADP 3
APS 3
THP 3
ADP 3
NADH 3
KDN 3
Ile 3
Tunicamycin 3
PMA 3
NADPH 3
Dexamethasone 3
hyaluronic acid 2
UMP 2
CAM 2
phosphite 2
acrylonitrile 2
Lactose 2
selenium 2
STZ 2
2-aminobenzoic acid 2
Trypsin 2
tryptophan 2
glutamine 2
Estradiol 2
2-aminobenzoic acid 2
UDP-N-acetylgalactosamine 2
nitrate 2
xylose 2
MAL 2
PEG 2
GAL 2
Neuronal 2
N-hydroxysuccinimide ester 2
Amide 2
PMA 2
N-acetyl-D-glucosamine 2
NeuAcalpha2,6Galbeta1,4GlcNAc 2
PAN 2
tryptophan 2
more...