Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:2.4.2.8 (hypoxanthine-guanine phosphoribosyltransferase)
 2,527 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

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Human Gene/Protein
60S ribosomal protein L13 13.6
WEE1 homolog 13.6
D8C6 13.6
HPRT 13.0
hypoxanthine-guanine phosphoribosyltransferase 12.9
SARP3 12.6
BCT2 12.6
PPRibP 12.3
TOP2 beta 12.3
ZNF75 12.0
F8c 12.0
60S ribosomal protein L32 12.0
MAE3 11.6
sulfotransferase 1C1 11.6
ubiquitin specific peptidase 24 11.6
Tp120 11.3
engrailed homeobox 1 11.3
C12orf35 11.3
PRTFDC1 11.3
Mvp1 11.0
RHOXF1 11.0
RNF206 11.0
GUK1 10.9
hREV3 10.8
ALDH16A1 10.8
40S ribosomal protein S12 10.8
GMP reductase 10.7
60S acidic ribosomal protein P0 10.6
RML2 10.6
REV1 protein 10.6
phosphoribosyl pyrophosphate amidotransferase 10.6
UV20 10.5
cadherin-9 10.5
Adapter protein 10.5
succinate dehydrogenase complex subunit A 10.5
PIG11 10.5
SLC25A6 10.5
HMBS 10.4
USP24 10.3
Cysteine conjugate beta-lyase 10.3
hypoxanthine guanine phosphoribosyltransferase 10.2
guanine deaminase 10.2
hypoxanthine phosphoribosyltransferase 1 10.1
SRPR 10.0
adenylosuccinate synthase 10.0
amidophosphoribosyltransferase 10.0
PSA2 9.9
red cone pigment 9.9
RPL17 9.9
selenium binding protein 1 9.9
PGK 9.9
RPL13A 9.9
GANC 9.8
ribosomal protein L8 9.8
RPL13 9.7
RPS7 9.7
PPIA 9.7
adenylosuccinate synthetase 9.7
Inosine 5'-monophosphate dehydrogenase 9.7
CLK4 9.6
MDR/TAP 9.6
PHPT1 9.5
POLB 9.5
PRPS2 9.5
MCF2 9.5
SDHA 9.5
ATP5O 9.5
peptidylprolyl isomerase A 9.5
C8G 9.5
EIF4A2 9.5
VDAC-2 9.5
RPS4X 9.5
GYPC 9.4
ARAF1 9.4
RPL19 9.3
adenosine kinase 9.3
adenylosuccinate lyase 9.3
YWHAZ 9.3
ALDOC 9.3
HAT 9.3
more...
Disease
HPRT PARIS 13.6
Hyperuricemic nephropathy 13.6
Deficiency of uracil phosphoribosyltransferase 13.6
MRX46 12.6
Kelley-Seegmiller syndrome 12.5
Lesch-Nyhan syndrome 12.1
UMP synthase deficiency 12.0
purine metabolism disorder 10.8
blood neoplasm 10.5
PNP deficiency 9.7
gouty nephropathy 9.5
APRT deficiency 9.3
RP10 9.2
choreoathetosis 8.8
Galactosialidosis 8.7
adult soft tissue sarcoma 8.3
Shope fibroma 8.0
hyperuricemia 7.9
self-injurious behavior 7.8
CGL1 7.8
uricosuria 7.7
orotic aciduria 7.7
XPE 7.7
AT3 7.6
AT3 7.6
AT3 7.6
AT3 7.6
AT3 7.6
AT3 7.6
AT3 7.6
AT3 7.6
AT3 7.6
ADA deficiency 7.5
enzyme deficiency 7.5
mouse leukemia L1210 7.4
Fowlpox 7.3
basal ganglia disease 7.3
neurobehavioral problems 7.2
environmental carcinogenesis 7.2
gout 7.1
Gouty arthritis 6.9
self-destructive behavior 6.9
FANCD1 6.9
Burkitt-like lymphoma 6.8
DRD 6.7
tophi 6.7
MCL 6.4
xeroderma pigmentosum 6.4
X-linked hyper-IgM syndrome 6.4
salivary gland cancer 6.3
hyperargininemia 6.3
AN2 6.2
XP-A 6.2
hypobetalipoproteinemia 6.0
X-linked lymphoproliferative syndrome 5.9
XX males 5.9
meningoencephalomyelitis 5.9
XPD 5.9
CPL 5.8
FRAXA 5.8
XPG 5.8
Simpson-Golabi-Behmel syndrome 5.7
chronic myeloproliferative disorders 5.7
nephrolithiasis 5.7
CAE 5.7
color blindness 5.7
incontinentia pigmenti 5.6
CAE 5.6
radiation carcinogenesis 5.6
sialidosis 5.5
XPF 5.5
familial disorder 5.5
RARS 5.4
spastic diplegia 5.4
thyroid neoplasm 5.3
Immune thrombocytopenia 5.3
XPB 5.3
testicular carcinoma 5.3
dissociative disorder 5.2
malignant state 5.2
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Symptom
athetosis 6.6
chromosome marker 6.5
clumsiness 5.5
spasticity 5.1
dystonia 4.2
renal colic 4.0
chorea 3.6
HSA 3.1
oliguria 2.8
dysarthria 2.7
hypotonia 2.7
flank pain 2.5
dysuria 2.4
starvation 2.2
colic 2.0
hepatomegaly 1.1
constipation 0.3
vomiting 0.2
Ill 0.2
anorexia -0.1
ataxia -0.3
seizures -0.3
tremor -0.5
weakness -0.6
respiratory distress -0.6
nausea -0.9
fatigue -1.0
abdominal pain -1.3
diarrhea -2.2
anesthesia -3.1
pain -3.4
Drug
Thioguanine 10.6
Proflavin 10.3
6-Methylpurine 10.3
8-Azaguanine 9.9
2-Methoxyethanol 9.0
Cellcept 8.6
Cellcept 8.6
Formycin B 8.5
Neocarzinostatin 7.9
Deoxyadenosine 7.7
Adenosine deaminase 7.4
TMX 7.3
Lead acetate 7.3
Epivir 7.1
G418 7.0
Mutagen 6.9
Mycophenolic acid 6.8
Febuxostat 6.5
CFX 6.3
BH4 6.0
Aztec 5.9
ddI 5.8
Cytidine 5.8
Rasburicase 5.6
Propidium 5.6
Zmax 5.6
KCL 5.5
Areca 5.5
AZT 5.2
OTC 5.1
AZT 5.1
AGG 5.0
CTT 4.9
MEA 4.8
BLM 4.8
OMP 4.7
AmBisome 4.6
Acyclovir 4.6
AIC 4.6
OTC 4.6
DMAP 4.5
Helium 4.4
-deoxyadenosine 4.2
Ganciclovir 4.1
IFN-beta 4.1
TEL 4.0
TAT 4.0
Oxaliplatin 3.8
DNase I 3.8
Prednisone 3.6
EPI 3.6
AraC 3.6
FLP 3.5
ACT 3.5
Hypaque 3.5
Infliximab 3.5
Etoposide 3.5
Infliximab 3.5
MRC 3.5
Adriamycin 3.4
Azithromycin 3.4
Hypaque 3.4
Arsenic trioxide 3.3
ETS 3.3
Meth 3.2
Gleevec 3.1
MIL 3.0
PTC 2.9
Parkin 2.8
Parkin 2.8
IFN-gamma 2.6
Glycerol 2.4
Imatinib 2.3
Ouabain 2.3
Nitric Oxide 2.3
THF 2.2
ETA 2.2
Alanine 2.2
caffeine 2.0
Vitamin E 1.9
more...
Enzyme
hypoxanthine-guanine phosphoribosyltransferase 13.6
xanthine phosphoribosyltransferase 12.1
adenine phosphoribosyltransferase 11.7
formyltetrahydrofolate deformylase 11.3
inosine kinase 11.2
amidophosphoribosyltransferase 10.9
deoxyadenosine kinase 10.5
adenine deaminase 10.4
PRPP synthetase 10.4
GMP reductase 10.2
adenylosuccinate synthetase 9.7
purine nucleoside phosphorylase 9.4
adenylosuccinate lyase 9.4
guanase 9.3
adenosine kinase 9.3
GMP synthetase 9.2
uridine hydrolase 9.1
EC 1.3.2.3 9.0
nicotinic acid phosphoribosyltransferase 9.0
orotate phosphoribosyltransferase 8.9
phosphoglycerate kinase 8.9
GMP synthase 8.8
adenosine nucleosidase 8.8
AICAR transformylase 8.8
deoxyguanosine kinase 8.8
nucleoside phosphotransferase 8.8
IMP dehydrogenase 8.7
ribokinase 8.4
IMP cyclohydrolase 8.3
DHOdehase 8.2
AMP deaminase 8.2
PRT 7.8
CTP synthase 7.7
3-hydroxyanthranilic acid oxygenase 7.6
orotidine-5'-phosphate decarboxylase 7.6
uracil phosphoribosyltransferase 7.5
glycinamide ribonucleotide transformylase 7.4
methylthioadenosine phosphorylase 7.3
inosine triphosphatase 7.3
CMP kinase 7.3
3'-phosphatase 7.2
deoxycytidine deaminase 7.2
deoxycytidine kinase 7.2
gluconate dehydrogenase 7.2
adenosine deaminase 7.2
adenosine deaminase 7.1
5'-nucleotidase 6.9
thymidine kinase 6.9
porphobilinogen deaminase 6.9
phosphomannose isomerase 6.7
guanylate kinase 6.7
penicillopepsin 6.7
nicotinamide mononucleotide adenylyltransferase 6.6
glyceraldehyde-3-phosphate dehydrogenase 6.6
ADH3 6.6
tripeptidase 6.6
S-adenosyl-L-homocysteine hydrolase 6.5
prolinase 6.5
alpha-galactosidase 6.5
glucose-6-phosphate dehydrogenase 6.4
dihydroorotase 6.4
uridine phosphorylase 6.4
nucleoside diphosphokinase 6.3
NMT 6.2
Fpg protein 6.2
thiopurine methyltransferase 6.1
PIP kinase 6.0
EC 1.1.1.40 5.9
galactokinase 5.9
uridine kinase 5.9
cyclohydrolase 5.9
CGT 5.8
dihydrodiol dehydrogenase 5.8
glyceraldehyde-3-phosphate dehydrogenase 5.7
formaldehyde dehydrogenase 5.7
PPH 5.7
cytidine deaminase 5.7
deoxyribonuclease 5.7
xanthine dehydrogenase 5.7
glyceraldehyde-3-phosphate dehydrogenase 5.6
more...
Compound
6-Ethylmercaptopurine 13.6
Methylmercuric hydroxide 13.6
C10H12N4O5S 12.6
C7H8N4S 11.6
Marmesin 11.6
Disperse Red 11 11.3
Radium-224 11.3
R 48 11.0
Marmesin 10.8
6-Mercaptopurine riboside 10.8
R 7000 10.6
Tiazofurin 10.4
Hypoxanthine 10.4
Inosinic acid 10.3
6-Methylpurine 10.3
6-Thioguanine 10.2
C5H5NO 10.0
6-Methylpurine 10.0
Xanthosine 9.8
Myosmine 9.7
methoxyacetaldehyde 9.6
Orotidine 9.5
1,6-Dinitropyrene 9.3
XMP 9.3
PRPP 9.3
Coformycin 9.2
Trenbolone 9.1
IMP 8.9
2,6-DMA 8.6
2,5-DCP 8.6
Perillaldehyde 8.5
4-vinylbenzoic acid 8.5
Purine 8.5
Formycin B 8.5
Formycin B 8.5
1-pyrenol 8.4
4-Aminobiphenyl 8.3
vinyl laurate 8.3
Glycidol 8.3
CI-921 8.2
1,3-Butadiene 8.2
dGDP 8.2
Angelicin 8.2
Xanthine 8.1
7H-dibenzo[c,g]carbazole 8.1
Diepoxybutane 8.0
6-Mercaptopurine 8.0
Glycidyl methacrylate 7.9
Radon-222 7.9
Inosine 7.9
Neocarzinostatin 7.9
Deoxyadenosine 7.7
adenylosuccinate 7.7
Azan 7.6
1,2-butanediol 7.6
2-ethylhexyl acrylate 7.6
MNNG 7.5
Benzidine 7.4
3-methoxybenzamide 7.3
ABPP 7.2
N-ethylurea 7.2
Deoxyguanosine 7.2
Guanidinoacetic acid 7.1
1-methylhistidine 7.1
5-Methylcytosine 7.1
GMP 7.0
2,5-dichlorophenol 7.0
WR-1065 7.0
NOP 7.0
O6-Methylguanine 7.0
Steviol 6.9
TBP 6.9
Ethionine 6.9
dGTP 6.9
TGR 6.9
bromoacetic acid 6.8
Acivicin 6.8
MOCA 6.8
TBP 6.7
Adenine 6.7
more...