Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

---

Query: EC:2.4.2.8 (hypoxanthine-guanine phosphoribosyltransferase)
2,527 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein hypoxanthine-guanine phosphoribosyltransferase 1475 HPRT 1096 Mol 315 AMP 205 Sep 193 X-linked 163 IMP 113 purine nucleoside phosphorylase 76 thymidine kinase 74 GMP 73 HAT 61 ATP 58 X-chromosome 57 adenosine deaminase 57 fused 56 GTP 53 adenosine kinase 51 housekeeping 50 glucose-6-phosphate dehydrogenase 50 G6PD 47 phosphoglycerate kinase 45 PGK 40 p53 40 GAPDH 39 xanthine oxidase 33 5'-nucleotidase 27 X-linked recessive 26 ATPase 26 ACTB 23 hemoglobin 21 SDHA 20 beta-actin 20 NAD 19 lymphoid 18 glyceraldehyde-3-phosphate dehydrogenase 17 Gen 17 cytokine 17 hypoxanthine guanine phosphoribosyltransferase 16 B2M 16 polypeptide 15 more...

Disease Lesch-Nyhan syndrome 297 cancer 261 tumor 103 carcinogenesis 91 hyperuricemia 71 gout 56 leukemia 51 mental retardation 40 mental retardation 40 lymphoma 40 carcinoma 29 hepatocellular carcinoma 26 arthritis 25 neuroblastoma 24 choreoathetosis 21 xeroderma pigmentosum 20 enzyme deficiency 19 immunodeficiency 18 self-injurious behavior 17 acute promyelocytic leukemia 17 anemia 15 acute lymphoblastic leukemia 15 renal failure 15 lung cancer 14 breast cancer 14 HIV 14 tumorigenesis 13 Schistosoma mansoni 13 herpes simplex 12 infectious diseases 12 Epstein 12 Fanconi 12 fibrosarcoma 12 nephrolithiasis 11 genetic disorder 11 chronic myeloid leukemia 10 neoplastic transformation 10 CEM 10 renal disease 10 acute myeloid leukemia 10 more...

Symptom spasticity 18 dystonia 12 starvation 9 seizures 5 hypotonia 3 vomiting 3 weakness 2 dysarthria 2 clumsiness 2 athetosis 2 chorea 2 pain 2 HSA 2 fatigue 2 diarrhea 1 Ill 1 anorexia 1 nausea 1 colic 1 abdominal pain 1 respiratory distress 1 flank pain 1 renal colic 1 ataxia 1 anesthesia 1 constipation 1 dysuria 1 oliguria 1 tremor 1 chromosome marker 1 hepatomegaly 1

Drug Mutagen 57 G418 22 lysine 15 IFN-gamma 14 DNase I 9 Adenosine deaminase 9 BH4 8 AZT 8 AZT 8 caffeine 7 IL-2 7 Adriamycin 4 ascorbate 4 IFN-beta 4 Thioguanine 4 Mycophenolic acid 3 THF 3 Gel 3 TAT 3 vitamin E 3 BLM 3 Dermatol 3 MRC 3 -deoxyadenosine 3 CSF 2 EPI 2 AGG 2 ACT 2 ddI 2 OTC 2 Deoxyadenosine 2 Neocarzinostatin 2 NADH 2 8-Azaguanine 2 OTC 2 Lead acetate 2 EPA 2 ETS 2 Asn 2 Acyclovir 2 more...

Enzyme hypoxanthine-guanine phosphoribosyltransferase 2527 adenine phosphoribosyltransferase 179 phosphoglycerate kinase 81 purine nucleoside phosphorylase 76 thymidine kinase 74 adenosine deaminase 59 adenosine deaminase 57 glucose-6-phosphate dehydrogenase 54 glyceraldehyde-3-phosphate dehydrogenase 51 adenosine kinase 47 xanthine oxidase 31 5'-nucleotidase 31 IMP dehydrogenase 30 ATPase 27 PRPP synthetase 26 xanthine phosphoribosyltransferase 25 glyceraldehyde-3-phosphate dehydrogenase 24 amidophosphoribosyltransferase 18 glyceraldehyde-3-phosphate dehydrogenase 18 glyceraldehyde-3-phosphate dehydrogenase 17 glyceraldehyde-3-phosphate dehydrogenase 17 AMP deaminase 16 endonuclease 15 reverse transcriptase 15 adenylosuccinate synthetase 14 orotate phosphoribosyltransferase 13 DNA polymerase 13 dihydrofolate reductase 13 ERK 12 alpha-galactosidase 12 guanase 12 superoxide dismutase 12 deaminase 12 RNA polymerase 11 glutathione S-transferase 11 adenine deaminase 11 catalase 11 beta-galactosidase 10 adenylosuccinate lyase 10 aldehyde dehydrogenase 9 more...

Compound DNA 806 Dec 191 IMP 116 GMP 94 Clin 80 pyrene 61 pyrimidine 59 pyrimidine 59 phosphate 59 ATP 58 AMP 58 GTP 55 sodium 51 oxygen 50 Hypoxanthine 41 EMS 32 arginine 28 Purine 27 water 26 lysine 22 His 20 NAD 20 acetate 19 NAD 19 nitrogen 18 hydrogen 18 glucose 17 uridine 17 DMSO 16 retinoic acid 16 methyl methanesulfonate 16 methionine 15 Guo 15 calcium 15 adenylate 15 DEAE 14 sulfate 14 Ile 13 valine 13 glutamine 13 more...

---