Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:2.4.2.8 (hypoxanthine-guanine phosphoribosyltransferase)
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Human Gene/Protein
60S ribosomal protein L13 13.6
WEE1 homolog 13.6
D8C6 13.6
HPRT 13.0
hypoxanthine-guanine phosphoribosyltransferase 12.9
BCT2 12.6
SARP3 12.6
PPRibP 12.3
TOP2 beta 12.3
60S ribosomal protein L32 12.0
ZNF75 12.0
F8c 12.0
MAE3 11.6
ubiquitin specific peptidase 24 11.6
sulfotransferase 1C1 11.6
engrailed homeobox 1 11.3
Tp120 11.3
PRTFDC1 11.3
C12orf35 11.3
RHOXF1 11.0
RNF206 11.0
Mvp1 11.0
GUK1 10.9
40S ribosomal protein S12 10.8
ALDH16A1 10.8
hREV3 10.8
GMP reductase 10.7
RML2 10.6
phosphoribosyl pyrophosphate amidotransferase 10.6
REV1 protein 10.6
60S acidic ribosomal protein P0 10.6
UV20 10.5
Adapter protein 10.5
cadherin-9 10.5
succinate dehydrogenase complex subunit A 10.5
SLC25A6 10.5
PIG11 10.5
HMBS 10.4
USP24 10.3
Cysteine conjugate beta-lyase 10.3
hypoxanthine guanine phosphoribosyltransferase 10.2
guanine deaminase 10.2
hypoxanthine phosphoribosyltransferase 1 10.1
SRPR 10.0
adenylosuccinate synthase 10.0
amidophosphoribosyltransferase 10.0
red cone pigment 9.9
selenium binding protein 1 9.9
PSA2 9.9
RPL17 9.9
PGK 9.9
RPL13A 9.9
GANC 9.8
ribosomal protein L8 9.8
RPL13 9.7
RPS7 9.7
PPIA 9.7
adenylosuccinate synthetase 9.7
Inosine 5'-monophosphate dehydrogenase 9.7
MDR/TAP 9.6
CLK4 9.6
MCF2 9.5
PRPS2 9.5
POLB 9.5
PHPT1 9.5
SDHA 9.5
ATP5O 9.5
C8G 9.5
peptidylprolyl isomerase A 9.5
EIF4A2 9.5
RPS4X 9.5
VDAC-2 9.5
ARAF1 9.4
GYPC 9.4
RPL19 9.3
adenosine kinase 9.3
adenylosuccinate lyase 9.3
YWHAZ 9.3
ALDOC 9.3
HAT 9.3
purine nucleoside phosphorylase 9.3
nicotinic acid phosphoribosyltransferase 9.3
RPL18 9.2
Guanine deaminase 9.2
acyl-protein thioesterase 9.2
ZNF224 9.2
LTV1 9.2
XMP 9.2
mannose phosphate isomerase 9.2
mutS homolog 6 9.2
MRPL19 9.2
aprt 9.2
CDH10 9.1
ribosomal protein P0 9.0
RPL30 9.0
Deoxyguanosine kinase 9.0
THO2 9.0
G6PD 9.0
B2M 9.0
RPLP0 9.0
DRP2 9.0
NADH-coenzyme Q reductase 9.0
GMP synthase 9.0
ECA39 9.0
ACTB 9.0
RPL4 8.9
BGR 8.9
IMP 8.9
A-9 8.9
LDHB 8.9
OPRT 8.9
KLK15 8.9
RPL8 8.8
ANXA11 8.8
alphaPIX 8.8
deoxyguanosine kinase 8.8
RPL7 8.8
GART 8.8
3-hydroxyanthranilate 3,4-dioxygenase 8.8
Tuba 8.7
Xg blood group 8.7
CAK1 8.7
GALA 8.6
adenosine monophosphate deaminase 8.6
nucleoside phosphorylase 8.6
THH 8.6
dGK 8.6
14-3-3 epsilon protein 8.6
AIRS 8.6
Rev-erb alpha 8.6
IMPDH2 8.6
IMPDH 8.6
G6PD protein 8.5
RPL22 8.5
phosphoglycerate kinase 8.5
hnRNPH 8.5
LAMR1 8.5
ribosomal protein L13a 8.5
hMSH3 8.5
RPL32 8.5
PLAC1 8.5
inosine triphosphatase 8.4
PGK1 8.4
RPS9 8.4
UXT 8.4
GAPD 8.4
betaine homocysteine methyltransferase 8.4
IDI1 8.4
MDH1 8.3
CYP2A3 8.3
EF1A 8.3
hPMS2 8.3
NEIL2 8.3
CCNG1 8.3
GMPS 8.3
Adenylosuccinate synthetase 8.3
TFRC 8.3
HPT1 8.3
tryptophan 5-monooxygenase 8.2
IMPDH1 8.2
adenylate kinase 1 8.2
ribosomal protein L19 8.2
NIP1 8.2
MGR 8.2
AGAT 8.2
GOT1 8.2
AMP deaminase 8.2
TUBB 8.2
MYH1 8.2
AHH 8.1
phenylalanine 4-monooxygenase 8.1
REV3L 8.1
GRIK1 8.1
ITPA 8.1
CD3E 8.1
hydroxymethylbilane synthase 8.0
RPS23 8.0
JMJD2D 8.0
RPS15 8.0
nucleoside-diphosphate kinase 8.0
SESN1 8.0
GUCY2C 8.0
PRPS1 8.0
ANT3 8.0
nuclear autoantigen 8.0
MAP kinase kinase 1 8.0
ADORA2A 8.0
5'-methylthioadenosine phosphorylase 7.9
ENO2 7.9
LDHA 7.9
REV1 7.9
CD8B 7.9
NOXA1 7.9
CGL1 7.9
ribosomal protein S5 7.9
AK3 7.9
APT1 7.9
GP120 7.9
TK1 7.9
ACSL5 7.9
NOXO1 7.9
ubiquitin C 7.8
methylthioadenosine phosphorylase 7.8
CDw40 7.8
Beta-actin 7.8
PEPA 7.8
homeotic protein 7.8
GST T1 7.8
PUM1 7.8
ZFX 7.8
FDXR 7.8
ALAS1 7.8
WNT7B 7.8
XPE 7.8
CBR3 7.7
CD27 ligand 7.7
12E7 7.7
ADSL 7.7
GAPDH 7.7
PNKP 7.7
proteasome subunit alpha 7.7
MIC1 7.7
glutamine amidotransferase 7.7
TOP2B 7.7
HUGO 7.7
PEPD 7.6
GMP 7.6
cytokeratin 15 7.6
X-chromosome 7.6
Pol iota 7.6
AT3 7.6
UBE1 7.6
KSR1 7.6
antiquitin 7.6
RBP2 7.6
RPS5 7.6
p84 7.6
Growth hormone receptor 7.5
dTMP kinase 7.5
UBC 7.5
DNA directed 7.5
PAIS 7.5
beta-polymerase 7.5
POLQ 7.5
SHMT 7.5
SLC16A2 7.4
PIG3 7.4
QR1 7.4
EN1 7.4
MRX 7.3
X-linked recessive 7.3
Kruppel-associated box 7.3
ATPase6 7.3
UBB 7.3
CTP synthetase 7.3
CASP2 7.3
ATIC 7.3
ANT2 7.3
PSP94 7.3
lamin B2 7.2
macrophage inhibitory factor 7.2
TCTA 7.2
deoxycytidine kinase 7.2
CASP4 7.2
POU3F4 7.2
Dihydroorotate dehydrogenase 7.2
TATA box binding protein 7.2
HEG 7.2
CDC10 7.2
ALF 7.2
MDH2 7.2
L41 7.2
MutS homolog 7.1
ALDOA 7.1
myc oncogene 7.1
hMSH2 7.1
adenosine deaminase 7.1
6PGD 7.1
ATP5B 7.1
beta actin 7.1
myoadenylate deaminase 7.1
GMK 7.1
poly(ADP-ribose) synthetase 7.1
NMNAT 7.1
RPS18 7.1
DNA-directed RNA polymerase 7.1
KDM4C 7.1
TNF receptor-associated factor 3 7.1
CDX1 7.0
PIP kinase 7.0
phosphoglycerate kinase 1 7.0
guanylate kinase 7.0
lactate dehydrogenase-A 7.0
TBP 7.0
thymidine kinase 7.0
transition protein 1 6.9
glycophorin A 6.9
X-linked 6.9
TGR 6.9
WNT11 6.9
Cadherin-11 6.9
squalene monooxygenase 6.9
hypoxia-inducible gene 6.9
UPS 6.9
14-3-3 zeta 6.9
ribokinase 6.9
MNF 6.8
DNA polymerase-alpha 6.8
TMX 6.8
PIG-A 6.8
glutathione-S-transferase M1 6.8
RNA polymerase II subunit 6.8
FANCD1 6.8
5'-nucleotidase 6.8
phosphatidylcholine transfer protein 6.8
phosphatidic acid phosphohydrolase 6.8
IL-22 receptor 6.8
UMP-CMP kinase 6.8
Thymidine kinase 6.8
alpha-galactosidase 6.8
more...
Disease
Hyperuricemic nephropathy 13.6
Deficiency of uracil phosphoribosyltransferase 13.6
HPRT PARIS 13.6
MRX46 12.6
Kelley-Seegmiller syndrome 12.5
Lesch-Nyhan syndrome 12.1
UMP synthase deficiency 12.0
purine metabolism disorder 10.8
blood neoplasm 10.5
PNP deficiency 9.7
gouty nephropathy 9.5
APRT deficiency 9.3
RP10 9.2
choreoathetosis 8.8
Galactosialidosis 8.7
adult soft tissue sarcoma 8.3
Shope fibroma 8.0
hyperuricemia 7.9
self-injurious behavior 7.8
CGL1 7.8
uricosuria 7.7
orotic aciduria 7.7
XPE 7.7
AT3 7.6
AT3 7.6
AT3 7.6
AT3 7.6
AT3 7.6
AT3 7.6
AT3 7.6
AT3 7.6
AT3 7.6
ADA deficiency 7.5
enzyme deficiency 7.5
mouse leukemia L1210 7.4
Fowlpox 7.3
basal ganglia disease 7.3
neurobehavioral problems 7.2
environmental carcinogenesis 7.2
gout 7.1
Gouty arthritis 6.9
self-destructive behavior 6.9
FANCD1 6.9
Burkitt-like lymphoma 6.8
DRD 6.7
tophi 6.7
MCL 6.4
xeroderma pigmentosum 6.4
X-linked hyper-IgM syndrome 6.4
salivary gland cancer 6.3
hyperargininemia 6.3
AN2 6.2
XP-A 6.2
hypobetalipoproteinemia 6.0
X-linked lymphoproliferative syndrome 5.9
XX males 5.9
meningoencephalomyelitis 5.9
XPD 5.9
CPL 5.8
FRAXA 5.8
XPG 5.8
Simpson-Golabi-Behmel syndrome 5.7
chronic myeloproliferative disorders 5.7
nephrolithiasis 5.7
CAE 5.7
color blindness 5.7
incontinentia pigmenti 5.6
CAE 5.6
radiation carcinogenesis 5.6
sialidosis 5.5
XPF 5.5
familial disorder 5.5
RARS 5.4
spastic diplegia 5.4
thyroid neoplasm 5.3
Immune thrombocytopenia 5.3
testicular carcinoma 5.3
XPB 5.3
dissociative disorder 5.2
malignant state 5.2
Fanconi 5.2
LYP 5.2
embryonal carcinoma 5.2
chemical carcinogenesis 5.2
Severe sepsis 5.1
STS 5.1
Lowe syndrome 5.1
blast crisis 5.1
HBB 5.1
HBB 5.1
HBB 5.1
SD1 5.1
Cockayne syndrome 5.0
relapsing fever 5.0
mental retardation 5.0
mental retardation 5.0
paroxysmal nocturnal hemoglobinuria 5.0
Sezary syndrome 5.0
Lowe 5.0
CEM 4.9
megaloblastic anemia 4.9
panhypopituitarism 4.9
RBS 4.9
second cancer 4.8
anosognosia 4.8
hemophilia B 4.8
acute promyelocytic leukemia 4.8
neoplastic transformation 4.7
HML 4.6
hereditary motor and sensory neuropathy 4.6
mild mental retardation 4.6
plasma cell leukemia 4.5
Fanconi syndrome 4.5
Schistosoma mansoni 4.5
folate deficiency 4.5
Ovary 4.5
HPP 4.5
amelanotic melanoma 4.5
refractory anemia 4.4
macrocytic anemia 4.4
HPP 4.4
Bradley 4.4
BLM 4.4
intestinal cancer 4.4
ventral hernia 4.4
secondary AML 4.4
fibrosarcoma 4.4
pyometra 4.3
Gilbert 4.3
GCT 4.3
abnormal involuntary movements 4.3
Borna disease 4.2
MPS II 4.2
AIC 4.2
X-linked agammaglobulinemia 4.2
fragile X syndrome 4.1
Schwannoma 4.1
Schwannoma 4.1
carcinogenesis 4.1
CREST 4.1
acute nonlymphocytic leukemia 4.1
mantle cell lymphoma 4.1
delirium tremens 4.1
WRN 4.1
chronic stable angina 4.1
multinodular goiter 4.0
RTS 4.0
neuroma 4.0
TMD 4.0
dysplastic nevi 4.0
NLS 4.0
Dandy-Walker malformation 4.0
genetic disorder 3.9
TCC 3.9
T-cell acute lymphoblastic leukemia 3.9
CNS diseases 3.9
giardiasis 3.9
Turner syndrome 3.9
histiocytic lymphoma 3.9
MAR 3.8
testicular atrophy 3.8
SCS 3.8
Ovary 3.8
skin tumor 3.7
Robinson 3.7
African trypanosomiasis 3.7
urolithiasis 3.7
DMS 3.7
sarcoma 180 3.6
IgA deficiency 3.6
AAA 3.6
MLC 3.6
childhood cancer 3.6
progeria 3.5
EPI 3.5
Wiskott-Aldrich syndrome 3.5
HOS 3.5
neurological disease 3.5
neuroblastoma 3.4
compulsion 3.4
vaccinia 3.4
tubular necrosis 3.3
childhood ALL 3.3
Appendix 3.3
Appendix 3.3
Appendix 3.3
Klinefelter's syndrome 3.3
PDE 3.3
Cushing's disease 3.3
trichomoniasis 3.3
hemangioendothelioma 3.3
glycogen storage disease 3.2
Hymenolepis 3.2
G6PD deficiency 3.2
erythroleukemia 3.2
HAM 3.2
leukemogenesis 3.2
pituitary tumor 3.2
developmental delay 3.2
adenomyosis 3.2
chronic myelomonocytic leukemia 3.2
brain dysfunction 3.2
Chagas 3.2
histiocytic lymphoma 3.1
severe mental retardation 3.1
acute lymphoblastic leukemia 3.1
nephrocalcinosis 3.1
seminoma 3.1
TTP 3.1
petechiae 3.1
Neumann 3.1
L. infantum 3.0
acute renal failure 3.0
macrocephaly 3.0
B-ALL 3.0
ATM 3.0
T-cell lymphoma 2.9
mammary tumor 2.9
latent infection 2.9
MIP 2.9
coccidiosis 2.9
failure to thrive 2.9
uropathy 2.8
azotemia 2.8
FBS 2.8
AGA 2.8
lymphoma 2.8
leukemia 2.8
renal insufficiency 2.8
chronic myeloid leukemia 2.7
Dissociation 2.7
NBS 2.7
cerebral palsy 2.7
uremia 2.7
gestational trophoblastic disease 2.7
myeloid leukemia 2.7
tapeworm 2.7
Spleen 2.7
Epstein 2.6
subacute sclerosing panencephalitis 2.6
primary myelofibrosis 2.6
synovial sarcoma 2.6
renal failure 2.6
Marek's disease 2.6
TTP 2.5
PHA 2.5
premature aging 2.5
ADH 2.5
ICH 2.5
ABL 2.5
gastrointestinal cancer 2.5
thymoma 2.4
herpes simplex 2.4
cryptosporidiosis 2.4
interstitial nephritis 2.4
diphtheria 2.4
metabolic disorder 2.3
myelodysplastic syndrome 2.3
Leukemia 2.3
idiopathic dilated cardiomyopathy 2.3
skin cancer 2.3
SCH 2.3
developmental disabilities 2.3
myeloproliferative disorders 2.3
Duchenne muscular dystrophy 2.3
human papilloma virus 2.3
human papilloma virus 2.3
germ cell tumor 2.3
trisomy 2.3
chronic granulomatous disease 2.2
Barrett's esophagus 2.2
DDP 2.2
Placenta 2.2
hepatocellular carcinoma 2.2
hepatoblastoma 2.2
SCID 2.2
arthritis 2.2
esophageal cancer 2.2
achalasia 2.2
Down syndrome 2.2
degenerative disease 2.1
herpes 2.1
EMT 2.1
abdominal aortic aneurysm 2.1
esophageal cancer 2.1
PSS 2.1
PSS 2.1
schistosomiasis 2.1
Rous sarcoma 2.1
acute leukemia 2.1
Burkitt's lymphoma 2.0
renal impairment 2.0
IVF 2.0
invasive cancer 2.0
Adenovirus 2.0
fibroma 2.0
CAP 2.0
giant cell arteritis 2.0
Chlamydia 2.0
Tourette syndrome 2.0
testicular cancer 1.9
hypogonadotropic hypogonadism 1.9
Rett syndrome 1.9
idiopathic thrombocytopenic purpura 1.9
NOD 1.9
infectious mononucleosis 1.9
polycythemia vera 1.9
DBA 1.9
lung carcinoma 1.9
APC 1.9
polyarthritis 1.9
anemia 1.9
thrombocytosis 1.8
acute myeloid leukemia 1.8
pulmonary fibrosis 1.8
IBM 1.8
leptospirosis 1.8
chronic lymphocytic leukemia 1.8
Wright 1.8
Lyme disease 1.8
more...
Symptom
athetosis 6.6
chromosome marker 6.5
clumsiness 5.5
spasticity 5.1
dystonia 4.2
renal colic 4.0
chorea 3.6
HSA 3.1
oliguria 2.8
dysarthria 2.7
hypotonia 2.7
flank pain 2.5
dysuria 2.4
starvation 2.2
colic 2.0
hepatomegaly 1.1
constipation 0.3
vomiting 0.2
Ill 0.2
anorexia -0.1
ataxia -0.3
seizures -0.3
tremor -0.5
weakness -0.6
respiratory distress -0.6
nausea -0.9
fatigue -1.0
abdominal pain -1.3
diarrhea -2.2
anesthesia -3.1
pain -3.4
Drug
Thioguanine 10.6
6-Methylpurine 10.3
Proflavin 10.3
8-Azaguanine 9.9
2-Methoxyethanol 9.0
Cellcept 8.6
Cellcept 8.6
Formycin B 8.5
Neocarzinostatin 7.9
Deoxyadenosine 7.7
Adenosine deaminase 7.4
TMX 7.3
Lead acetate 7.3
Epivir 7.1
G418 7.0
Mutagen 6.9
Mycophenolic acid 6.8
Febuxostat 6.5
CFX 6.3
BH4 6.0
Aztec 5.9
ddI 5.8
Cytidine 5.8
Rasburicase 5.6
Propidium 5.6
Zmax 5.6
KCL 5.5
Areca 5.5
AZT 5.2
OTC 5.1
AZT 5.1
AGG 5.0
CTT 4.9
MEA 4.8
BLM 4.8
OMP 4.7
AmBisome 4.6
Acyclovir 4.6
AIC 4.6
OTC 4.6
DMAP 4.5
Helium 4.4
-deoxyadenosine 4.2
Ganciclovir 4.1
IFN-beta 4.1
TEL 4.0
TAT 4.0
Oxaliplatin 3.8
DNase I 3.8
Prednisone 3.6
EPI 3.6
AraC 3.6
FLP 3.5
ACT 3.5
Hypaque 3.5
Infliximab 3.5
Etoposide 3.5
Infliximab 3.5
MRC 3.5
Adriamycin 3.4
Azithromycin 3.4
Hypaque 3.4
Arsenic trioxide 3.3
ETS 3.3
Meth 3.2
Gleevec 3.1
MIL 3.0
PTC 2.9
Parkin 2.8
Parkin 2.8
IFN-gamma 2.6
Glycerol 2.4
Imatinib 2.3
Ouabain 2.3
Nitric Oxide 2.3
THF 2.2
ETA 2.2
Alanine 2.2
caffeine 2.0
Vitamin E 1.9
Retinoic acid 1.9
EPA 1.8
lysine 1.7
Spectrum 1.6
IL-2 1.6
PCB 1.6
nitroglycerin 1.5
Gel 1.3
Glutathione 1.2
ICI 1.2
FAD 1.2
ascorbate 1.1
vitamin E 1.1
Asn 1.1
CaCl2 1.0
CaCl2 1.0
CaCl2 0.9
NH3 0.8
Spectrum 0.7
ABC 0.5
Nephron 0.5
CTX 0.3
NADH 0.2
Nephron 0.1
CSF -0.3
ampicillin -0.4
ROS -0.6
Dial -1.3
Dermatol -2.8
Enzyme
hypoxanthine-guanine phosphoribosyltransferase 13.6
xanthine phosphoribosyltransferase 12.1
adenine phosphoribosyltransferase 11.7
formyltetrahydrofolate deformylase 11.3
inosine kinase 11.2
amidophosphoribosyltransferase 10.9
deoxyadenosine kinase 10.5
adenine deaminase 10.4
PRPP synthetase 10.4
GMP reductase 10.2
adenylosuccinate synthetase 9.7
purine nucleoside phosphorylase 9.4
adenylosuccinate lyase 9.4
guanase 9.3
adenosine kinase 9.3
GMP synthetase 9.2
uridine hydrolase 9.1
EC 1.3.2.3 9.0
nicotinic acid phosphoribosyltransferase 9.0
orotate phosphoribosyltransferase 8.9
phosphoglycerate kinase 8.9
GMP synthase 8.8
AICAR transformylase 8.8
adenosine nucleosidase 8.8
deoxyguanosine kinase 8.8
nucleoside phosphotransferase 8.8
IMP dehydrogenase 8.7
ribokinase 8.4
IMP cyclohydrolase 8.3
DHOdehase 8.2
AMP deaminase 8.2
PRT 7.8
CTP synthase 7.7
3-hydroxyanthranilic acid oxygenase 7.6
orotidine-5'-phosphate decarboxylase 7.6
uracil phosphoribosyltransferase 7.5
glycinamide ribonucleotide transformylase 7.4
methylthioadenosine phosphorylase 7.3
inosine triphosphatase 7.3
CMP kinase 7.3
3'-phosphatase 7.2
deoxycytidine deaminase 7.2
deoxycytidine kinase 7.2
gluconate dehydrogenase 7.2
adenosine deaminase 7.2
adenosine deaminase 7.1
5'-nucleotidase 6.9
thymidine kinase 6.9
porphobilinogen deaminase 6.9
phosphomannose isomerase 6.7
guanylate kinase 6.7
penicillopepsin 6.7
nicotinamide mononucleotide adenylyltransferase 6.6
glyceraldehyde-3-phosphate dehydrogenase 6.6
ADH3 6.6
tripeptidase 6.6
S-adenosyl-L-homocysteine hydrolase 6.5
prolinase 6.5
alpha-galactosidase 6.5
glucose-6-phosphate dehydrogenase 6.4
dihydroorotase 6.4
uridine phosphorylase 6.4
nucleoside diphosphokinase 6.3
NMT 6.2
Fpg protein 6.2
thiopurine methyltransferase 6.1
PIP kinase 6.0
EC 1.1.1.40 5.9
galactokinase 5.9
uridine kinase 5.9
cyclohydrolase 5.9
CGT 5.8
dihydrodiol dehydrogenase 5.8
glyceraldehyde-3-phosphate dehydrogenase 5.7
formaldehyde dehydrogenase 5.7
PPH 5.7
cytidine deaminase 5.7
deoxyribonuclease 5.7
xanthine dehydrogenase 5.7
glyceraldehyde-3-phosphate dehydrogenase 5.6
nucleotidase 5.6
glyceraldehyde-3-phosphate dehydrogenase 5.6
CPL 5.6
glyceraldehyde-3-phosphate dehydrogenase 5.6
microsomal epoxide hydrolase 5.6
xanthine oxidase 5.5
alanine dehydrogenase 5.5
SpeB 5.5
dihydropyrimidinase 5.5
adenylate kinase 5.5
thymidylate kinase 5.5
HDR 5.4
alanine racemase 5.3
phosphoglycerate dehydrogenase 5.3
tryptophanyl-tRNA synthetase 5.3
propionyl-CoA carboxylase 5.2
propionyl-CoA carboxylase 5.2
anthranilate synthase 5.2
nicotinamide phosphoribosyltransferase 5.1
squalene epoxidase 5.1
aspartokinase 5.0
uricase 5.0
phosphoglucose isomerase 4.9
deaminase 4.9
dihydrofolate reductase 4.8
thymidylate synthase 4.8
6-phosphogluconate dehydrogenase 4.7
6-phosphogluconate dehydrogenase 4.7
carbonyl reductase 4.6
DOPA decarboxylase 4.6
aryl hydrocarbon hydroxylase 4.5
meprin 4.5
myrosinase 4.5
ornithine transcarbamylase 4.5
serine hydroxymethyltransferase 4.4
tryptophan hydroxylase 4.4
arylsulfatase 4.4
S1 nuclease 4.4
dihydropyrimidine dehydrogenase 4.4
TPP 4.3
GTP cyclohydrolase I 4.3
methionine adenosyltransferase 4.2
DNA ligase 4.2
DNA ligase 4.2
argininosuccinate synthetase 4.2
type III procollagen 4.2
GCA 4.2
phenylalanine hydroxylase 4.2
PGM 4.2
polynucleotide phosphorylase 4.1
aldehyde dehydrogenase 4.1
TPP 4.1
malate dehydrogenase 4.0
AGT 4.0
peptidyl-prolyl cis-trans isomerase 4.0
TAT 4.0
MDH 4.0
phosphorylase 4.0
dihydropyrimidine dehydrogenase 4.0
chloramphenicol acetyltransferase 3.9
TSP-1 3.9
phosphoenolpyruvate carboxylase 3.9
aspartate transcarbamylase 3.9
MDH 3.9
isocitrate dehydrogenase 3.9
PAH 3.8
S-adenosylmethionine decarboxylase 3.8
ALDH 3.8
micrococcal nuclease 3.7
histone demethylase 3.7
PTPase 3.6
glucose dehydrogenase 3.6
thymidine phosphorylase 3.6
STR 3.6
proprotein convertase 3.5
soluble epoxide hydrolase 3.5
N-acetyltransferase 3.4
Thy1 3.4
endonuclease 3.3
CPS 3.3
transketolase 3.3
pyruvate kinase 3.3
tyrosine aminotransferase 3.3
DNA polymerase 3.3
phosphoglucomutase 3.2
LPL 3.2
dopamine beta-hydroxylase 3.2
topoisomerase 3.2
ribonucleotide reductase 3.1
beta-galactosidase 3.1
ribonucleotide reductase 3.1
topoisomerase 3.0
deoxyribonuclease 3.0
isocitrate dehydrogenase 3.0
CYP3A4 3.0
MIP 2.9
UDP-glucuronosyltransferase 2.9
paraoxonase 2.9
glycerol-3-phosphate dehydrogenase 2.8
glycerol-3-phosphate dehydrogenase 2.8
prostaglandin synthetase 2.8
PDE 2.8
arginase 2.8
TdT 2.7
transcriptase 2.7
PRE 2.7
BAL 2.7
glutathione S-transferase 2.6
NQO1 2.6
cathepsin B 2.6
paraoxonase 2.6
reverse transcriptase 2.6
ADH 2.5
PDK1 2.5
tyrosinase 2.5
PARP 2.5
ATPase 2.4
DNA methyltransferase 2.3
PKG 2.3
beta-glucuronidase 2.3
peroxiredoxin 2.3
monoamine oxidase 2.2
sialidase 2.2
succinate dehydrogenase 2.2
firefly luciferase 2.2
complex I 2.1
carboxylesterase 2.1
AMPK 2.0
AMPK 2.0
ornithine decarboxylase 2.0
glutathione reductase 2.0
RNA polymerase 2.0
CPT 2.0
furin 2.0
sulfatase 2.0
P-glycoprotein 1.9
aldolase 1.9
CPT 1.9
enolase 1.8
carbonic anhydrase 1.8
urease 1.8
alanine aminotransferase 1.7
DNase 1.7
NADPH-diaphorase 1.7
CaMKII 1.6
proteinase K 1.6
AMP-activated protein kinase 1.5
CAD 1.5
aldehyde dehydrogenase 1.5
subtilisin 1.5
aldehyde dehydrogenase 1.5
CAD 1.5
aldehyde dehydrogenase 1.5
RNase 1.5
gamma-glutamyl transpeptidase 1.5
CAD 1.5
CPT 1.5
superoxide dismutase 1.4
tyrosine hydroxylase 1.4
catalase 1.3
ceruloplasmin 1.3
NADPH oxidase 1.3
aldehyde dehydrogenase 1.3
CPR 1.3
trypsin 1.3
hexokinase 1.3
glucose oxidase 1.2
RNase 1.2
demethylase 1.2
NADPH oxidase 1.2
tissue plasminogen activator 1.2
alkaline phosphatase 1.1
kallikrein 1.1
AST 1.1
caspase-1 1.0
choline acetyltransferase 1.0
ATP synthase 0.8
neuraminidase 0.8
urease 0.8
NOS 0.8
lactate dehydrogenase 0.8
focal adhesion kinase 0.8
NO synthase 0.7
ERK 0.7
elastase 0.5
collagenase 0.5
alcohol dehydrogenase 0.4
phosphodiesterase 0.4
adenylate cyclase 0.4
protein kinase 0.3
urokinase-type plasminogen activator 0.2
lysozyme 0.2
peroxidase 0.2
glutathione peroxidase 0.2
phosphatidylinositol 3-kinase 0.2
luciferase -0.0
acid phosphatase -0.0
proteasome -0.2
APC -0.4
renin -0.5
MEK -0.5
lipase -0.6
creatine kinase -0.6
aspartate aminotransferase -0.8
acetylcholinesterase -1.2
mitogen-activated protein kinase -1.3
protein kinase C -2.0
ACS -2.6
Compound
Methylmercuric hydroxide 13.6
6-Ethylmercaptopurine 13.6
C10H12N4O5S 12.6
C7H8N4S 11.6
Marmesin 11.6
Radium-224 11.3
Disperse Red 11 11.3
R 48 11.0
Marmesin 10.8
6-Mercaptopurine riboside 10.8
R 7000 10.6
Tiazofurin 10.4
Hypoxanthine 10.4
6-Methylpurine 10.3
Inosinic acid 10.3
6-Thioguanine 10.2
6-Methylpurine 10.0
C5H5NO 10.0
Xanthosine 9.8
Myosmine 9.7
methoxyacetaldehyde 9.6
Orotidine 9.5
1,6-Dinitropyrene 9.3
XMP 9.3
PRPP 9.3
Coformycin 9.2
Trenbolone 9.1
IMP 8.9
2,6-DMA 8.6
2,5-DCP 8.6
Perillaldehyde 8.5
4-vinylbenzoic acid 8.5
Purine 8.5
Formycin B 8.5
Formycin B 8.5
1-pyrenol 8.4
4-Aminobiphenyl 8.3
vinyl laurate 8.3
Glycidol 8.3
1,3-Butadiene 8.2
CI-921 8.2
dGDP 8.2
Angelicin 8.2
Xanthine 8.1
7H-dibenzo[c,g]carbazole 8.1
Diepoxybutane 8.0
6-Mercaptopurine 8.0
Glycidyl methacrylate 7.9
Radon-222 7.9
Inosine 7.9
Neocarzinostatin 7.9
Deoxyadenosine 7.7
adenylosuccinate 7.7
Azan 7.6
1,2-butanediol 7.6
2-ethylhexyl acrylate 7.6
MNNG 7.5
Benzidine 7.4
3-methoxybenzamide 7.3
N-ethylurea 7.2
ABPP 7.2
Deoxyguanosine 7.2
Guanidinoacetic acid 7.1
1-methylhistidine 7.1
5-Methylcytosine 7.1
GMP 7.0
2,5-dichlorophenol 7.0
WR-1065 7.0
NOP 7.0
O6-Methylguanine 7.0
Steviol 6.9
TBP 6.9
Ethionine 6.9
dGTP 6.9
TGR 6.9
bromoacetic acid 6.8
Acivicin 6.8
MOCA 6.8
TBP 6.7
Adenine 6.7
dibromomethane 6.6
Styrene 6.6
EMS 6.5
HPP 6.5
triethyl phosphate 6.5
4-NQO 6.4
methyl methanesulfonate 6.4
Palmitoleic acid 6.3
alpha-Naphthoflavone 6.3
alpha-Naphthoflavone 6.3
alpha-Naphthoflavone 6.3
Cyd 6.2
benzo[ghi]perylene 6.2
2-imidazolidinone 6.2
methoxyacetic acid 6.2
dGMP 6.1
Thymine 6.1
2-methoxyethyl 6.1
AAF 6.1
2-methoxyethyl 6.1
3-aminobenzamide 6.1
SC-1 6.0
SC-1 6.0
ENU 6.0
Filipin 6.0
GA2 6.0
Domoic acid 5.9
ribose-5-phosphate 5.9
5-Azacytidine 5.9
CPL 5.8
ethyl acrylate 5.8
Geigy 5.8
methylphosphonic acid 5.8
methylphosphonic acid 5.8
Adenine 5.8
BOP 5.7
methylphosphonic acid 5.7
Guanine 5.7
Benzo[a]pyrene 5.7
MGBG 5.7
MGBG 5.7
BUdR 5.7
chloroacetic acid 5.7
dCTP 5.7
pentanal 5.6
PPi 5.6
Ethylene oxide 5.6
4-Hydroxynonenal 5.6
Novobiocin 5.6
pentanal 5.6
MNU 5.6
m-AMSA 5.6
HCP 5.6
benzo[a]anthracene 5.5
BSH 5.5
5H-pyrido[4,3-b]indole 5.5
AICAR 5.5
Tocopherols 5.5
2-methoxyethanol 5.4
NaAsO2 5.4
IDP 5.3
Diacetyl 5.3
Guo 5.3
2,2,6,6-tetramethylpiperidine 5.3
MNU 5.3
pyrene 5.3
Parks 5.3
methyl acrylate 5.2
Sitosterol 5.2
HMF 5.2
pyrimidine 5.2
Azathioprine 5.2
pyrimidine 5.2
dATP 5.2
D-glucuronate 5.1
Ribose 5.1
Tiron 5.1
DMAP 5.1
DMAP 5.1
HBB 5.1
AICAR 5.1
NMA 5.1
HEI 5.1
Hydrazine 5.0
nonyl 5.0
3TC 5.0
DMS 5.0
GPT 5.0
HN2 5.0
AZT 5.0
PHE 5.0
AIR 5.0
4-methoxybenzyl 5.0
Ribavirin 4.9
adenylate 4.9
G20 4.9
Morin 4.9
acrylonitrile 4.9
3-methylindole 4.8
MAOA 4.8
MEA 4.8
cinnamyl 4.8
Vanillin 4.8
UTP 4.7
Cortisone 4.7
ETH 4.7
Uric acid 4.7
G11 4.7
DCB 4.7
GA1 4.7
OMP 4.7
DCB 4.6
Acyclovir 4.6
Ochratoxin A 4.6
Ifosfamide 4.6
GAL 4.6
ECP 4.6
GTP 4.6
ECP 4.5
ECP 4.5
DMAP 4.5
Neo 4.5
MTA 4.5
BLM 4.5
Malate 4.5
UMP 4.5
DMD 4.5
DCB 4.5
2-hexenal 4.5
Hydroxyurea 4.5
glucose-6-phosphate 4.4
Camptothecin 4.4
Camptothecin 4.4
Camptothecin 4.4
CTP 4.4
Arsenite 4.4
butanal 4.3
TDI 4.3
2-hydroxyethyl 4.3
2-hydroxyethyl 4.3
2-hydroxyethyl 4.3
2-hydroxyethyl 4.3
2-hydroxyethyl 4.3
2-hydroxyethyl 4.3
2-hydroxyethyl 4.3
GGG 4.3
aflatoxin B1 4.2
MMC 4.2
HBA 4.2
Acrolein 4.2
Glucosamine 4.2
Adenosine 4.2
DCB 4.2
Thymidine 4.2
TPP 4.2
TTP 4.2
Dichloroacetate 4.2
AMP 4.1
PNP 4.1
MTX 4.1
uridine 4.1
DCB 4.0
BSO 4.0
indole-3-carbinol 4.0
DEA 4.0
DEA 4.0
3-methylhistidine 4.0
Guo 4.0
Uridine 4.0
TEL 4.0
DON 4.0
d4T 4.0
2-hydroxyethyl 4.0
DEA 3.9
HIS 3.9
MOD 3.9
VM-26 3.9
TPP 3.9
2-butanone 3.8
PAH 3.8
TCC 3.8
Rutin 3.8
DCM 3.8
CCC 3.8
CCC 3.7
Glutaraldehyde 3.7
MOP 3.7
Coumarin 3.7
MSM 3.7
AAA 3.7
PAC 3.7
Cyt 3.7
nicotinic acid 3.7
nicotinic acid 3.7
Methotrexate 3.7
Nitroglycerin 3.6
ITP 3.6
DMSO 3.6
DNA 3.6
PHB 3.6
anthracene 3.6
nicotinic acid 3.6
NAD 3.6
acrylonitrile 3.6
nicotinic acid 3.6
DEAE 3.5
HBr 3.5
cyclopentane 3.5
methylhistamine 3.5
L-T3 3.5
MEP 3.5
BCNU 3.5
valine 3.5
NADP 3.5
Wortmannin 3.5
TPP 3.5
DMPC 3.5
aspartic acid 3.4
aspartic acid 3.4
Belt 3.4
fMet 3.4
acetaldehyde 3.4
thioglycollate 3.4
Bisulfite 3.3
chrysene 3.3
isoleucine 3.3
PAR 3.3
aspartic acid 3.3
Hypaque 3.3
isoleucine 3.3
DFO 3.3
DIC 3.3
NAD 3.3
Titanium dioxide 3.2
TPA 3.2
hexanal 3.2
GDP 3.2
Triton 3.2
aspartic acid 3.2
DAMP 3.1
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