Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:2.4.2.8 (hypoxanthine-guanine phosphoribosyltransferase)
 2,527 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
WEE1 homolog 13.6
D8C6 13.6
60S ribosomal protein L13 13.6
HPRT 13.0
hypoxanthine-guanine phosphoribosyltransferase 12.9
BCT2 12.6
SARP3 12.6
TOP2 beta 12.3
PPRibP 12.3
F8c 12.0
60S ribosomal protein L32 12.0
ZNF75 12.0
MAE3 11.6
ubiquitin specific peptidase 24 11.6
sulfotransferase 1C1 11.6
engrailed homeobox 1 11.3
Tp120 11.3
PRTFDC1 11.3
C12orf35 11.3
RHOXF1 11.0
more...
Disease
Deficiency of uracil phosphoribosyltransferase 13.6
HPRT PARIS 13.6
Hyperuricemic nephropathy 13.6
MRX46 12.6
Kelley-Seegmiller syndrome 12.5
Lesch-Nyhan syndrome 12.1
UMP synthase deficiency 12.0
purine metabolism disorder 10.8
blood neoplasm 10.5
PNP deficiency 9.7
gouty nephropathy 9.5
APRT deficiency 9.3
RP10 9.2
choreoathetosis 8.8
Galactosialidosis 8.7
adult soft tissue sarcoma 8.3
Shope fibroma 8.0
hyperuricemia 7.9
self-injurious behavior 7.8
CGL1 7.8
more...
Symptom
athetosis 6.6
chromosome marker 6.5
clumsiness 5.5
spasticity 5.1
dystonia 4.2
renal colic 4.0
chorea 3.6
HSA 3.1
oliguria 2.8
dysarthria 2.7
hypotonia 2.7
flank pain 2.5
dysuria 2.4
starvation 2.2
colic 2.0
hepatomegaly 1.1
constipation 0.3
vomiting 0.2
Ill 0.2
anorexia -0.1
more...
Drug
Thioguanine 10.6
Proflavin 10.3
6-Methylpurine 10.3
8-Azaguanine 9.9
2-Methoxyethanol 9.0
Cellcept 8.6
Cellcept 8.6
Formycin B 8.5
Neocarzinostatin 7.9
Deoxyadenosine 7.7
Adenosine deaminase 7.4
TMX 7.3
Lead acetate 7.3
Epivir 7.1
G418 7.0
Mutagen 6.9
Mycophenolic acid 6.8
Febuxostat 6.5
CFX 6.3
BH4 6.0
more...
Enzyme
hypoxanthine-guanine phosphoribosyltransferase 13.6
xanthine phosphoribosyltransferase 12.1
adenine phosphoribosyltransferase 11.7
formyltetrahydrofolate deformylase 11.3
inosine kinase 11.2
amidophosphoribosyltransferase 10.9
deoxyadenosine kinase 10.5
adenine deaminase 10.4
PRPP synthetase 10.4
GMP reductase 10.2
adenylosuccinate synthetase 9.7
purine nucleoside phosphorylase 9.4
adenylosuccinate lyase 9.4
guanase 9.3
adenosine kinase 9.3
GMP synthetase 9.2
uridine hydrolase 9.1
EC 1.3.2.3 9.0
nicotinic acid phosphoribosyltransferase 9.0
orotate phosphoribosyltransferase 8.9
more...
Compound
6-Ethylmercaptopurine 13.6
Methylmercuric hydroxide 13.6
C10H12N4O5S 12.6
C7H8N4S 11.6
Marmesin 11.6
Disperse Red 11 11.3
Radium-224 11.3
R 48 11.0
6-Mercaptopurine riboside 10.8
Marmesin 10.8
R 7000 10.6
Tiazofurin 10.4
Hypoxanthine 10.4
6-Methylpurine 10.3
Inosinic acid 10.3
6-Thioguanine 10.2
6-Methylpurine 10.0
C5H5NO 10.0
Xanthosine 9.8
Myosmine 9.7
more...