Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

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Query: EC:2.4.2.8 (hypoxanthine-guanine phosphoribosyltransferase)
2,527 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein hypoxanthine-guanine phosphoribosyltransferase 1475 HPRT 1096 Mol 315 AMP 205 Sep 193 X-linked 163 IMP 113 purine nucleoside phosphorylase 76 thymidine kinase 74 GMP 73 HAT 61 ATP 58 X-chromosome 57 adenosine deaminase 57 fused 56 GTP 53 adenosine kinase 51 housekeeping 50 glucose-6-phosphate dehydrogenase 50 G6PD 47 more...

Disease Lesch-Nyhan syndrome 297 cancer 261 tumor 103 carcinogenesis 91 hyperuricemia 71 gout 56 leukemia 51 lymphoma 40 mental retardation 40 mental retardation 40 carcinoma 29 hepatocellular carcinoma 26 arthritis 25 neuroblastoma 24 choreoathetosis 21 xeroderma pigmentosum 20 enzyme deficiency 19 immunodeficiency 18 acute promyelocytic leukemia 17 self-injurious behavior 17 more...

Symptom spasticity 18 dystonia 12 starvation 9 seizures 5 vomiting 3 hypotonia 3 fatigue 2 weakness 2 pain 2 HSA 2 clumsiness 2 athetosis 2 chorea 2 dysarthria 2 diarrhea 1 Ill 1 anorexia 1 nausea 1 colic 1 flank pain 1 more...

Drug Mutagen 57 G418 22 lysine 15 IFN-gamma 14 DNase I 9 Adenosine deaminase 9 AZT 8 AZT 8 BH4 8 IL-2 7 caffeine 7 ascorbate 4 Adriamycin 4 Thioguanine 4 IFN-beta 4 Dermatol 3 THF 3 Gel 3 Mycophenolic acid 3 BLM 3 more...

Enzyme hypoxanthine-guanine phosphoribosyltransferase 2527 adenine phosphoribosyltransferase 179 phosphoglycerate kinase 81 purine nucleoside phosphorylase 76 thymidine kinase 74 adenosine deaminase 59 adenosine deaminase 57 glucose-6-phosphate dehydrogenase 54 glyceraldehyde-3-phosphate dehydrogenase 51 adenosine kinase 47 xanthine oxidase 31 5'-nucleotidase 31 IMP dehydrogenase 30 ATPase 27 PRPP synthetase 26 xanthine phosphoribosyltransferase 25 glyceraldehyde-3-phosphate dehydrogenase 24 amidophosphoribosyltransferase 18 glyceraldehyde-3-phosphate dehydrogenase 18 glyceraldehyde-3-phosphate dehydrogenase 17 more...

Compound DNA 806 Dec 191 IMP 116 GMP 94 Clin 80 pyrene 61 phosphate 59 pyrimidine 59 pyrimidine 59 AMP 58 ATP 58 GTP 55 sodium 51 oxygen 50 Hypoxanthine 41 EMS 32 arginine 28 Purine 27 water 26 lysine 22 more...

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