Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:2.4.2.8 (
hypoxanthine-guanine phosphoribosyltransferase
)
2,527
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Adenosine deaminase (ADA), purine nucleoside phosphorylase (PNP), and
hypoxanthine-guanine phosphoribosyltransferase
(
HGPRT
) activities were measured in normal human B lymphocytes, T lymphocytes, and
T gamma
and T mu lymphocyte subsets. Total ADA activity in T cells was 5.5U, activity in
T gamma
and T mu cells was 3.7U and 5.3U, respectively; B cell ADA levels were 3.3U. PNP activity in T cells was 119U, activity in
T gamma
and T mu cells was 75U and 155U, respectively. B cell PNP activity was 88U.
HGPRT
activity in T cells was 20.9U;
T gamma
and T mu
HGPRT
levels were 13.0U and 52U respectively. B cell
HGPRT
levels were 46.8U. These data provides further evidence for the biochemical heterogeneity of normal human lymphocytes.
...
PMID:Adenosine deaminase, nucleoside phosphorylase and hypoxanthine-guanine phosphoribosyltransferase activity in normal lymphocyte subpopulations. 681 86
