Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:2.4.2.7 (adenine phosphoribosyltransferase)
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Human Gene/Protein
D16S444E 15.5
tetratricopeptide repeat domain 9C 15.5
vacuolar protein sorting 33A 13.9
aprt 13.5
PPRibP 13.2
transmembrane protein 33 13.2
3',5'-cyclic AMP phosphodiesterase 12.9
POLR2C 12.9
phosphoribosyl pyrophosphate amidotransferase 12.5
SLC43A3 12.5
adenylate kinase 3 12.5
POLR2F 12.5
APT1 12.3
NME5 12.2
5'-methylthioadenosine phosphorylase 12.1
PDHA2 12.0
hypoxanthine guanine phosphoribosyltransferase 11.9
uridine-cytidine kinase 2 11.9
microsomal signal peptidase 11.9
ENTPD3 11.9
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Disease
Deficiency of uracil phosphoribosyltransferase 15.5
APRT*J 15.0
APRT deficiency 15.0
UMP synthase deficiency 13.9
purine metabolism disorder 12.7
gouty nephropathy 11.4
Lesch-Nyhan syndrome 10.7
AT3 10.5
AT3 10.5
AT3 10.5
AT3 10.5
AT3 10.5
AT3 10.5
AT3 10.5
AT3 10.5
AT3 10.5
PNP deficiency 10.2
Serous carcinoma 10.0
colon neoplasm 9.6
orotic aciduria 9.6
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Symptom
renal colic 7.4
flank pain 6.4
muscle stiffness 5.2
dysuria 4.2
colic 3.9
spasticity 3.8
starvation 3.5
dystonia 2.5
vomiting 0.5
weakness 0.3
seizures 0.2
diarrhea -0.3
pain -0.9
Drug
6-Methylpurine 13.2
Adenyl 10.8
Mizoribine 8.9
Adenosine deaminase 8.7
Deoxyadenosine 8.5
Cytidine 7.6
Cellulose acetate 7.4
-deoxyadenosine 7.3
ATV 6.9
OMP 6.6
FLP 6.4
TAT 6.3
AGG 5.9
Mutagen 5.8
TTC 5.6
Acyclovir 5.5
DMAP 5.3
BLM 5.1
ACT 4.4
G418 4.4
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Enzyme
adenine phosphoribosyltransferase 15.5
adenosine nucleosidase 13.5
inosine kinase 13.4
xanthine phosphoribosyltransferase 13.1
adenine deaminase 12.9
amidophosphoribosyltransferase 12.0
hypoxanthine-guanine phosphoribosyltransferase 11.7
5'-methylthioadenosine nucleosidase 11.4
PRPP synthetase 11.4
adenosine kinase 11.3
GMP reductase 11.3
nitric-oxide reductase 11.1
uridine hydrolase 11.0
adenylosuccinate lyase 10.9
ribokinase 10.6
nucleoside phosphotransferase 10.6
guanase 10.6
AMP nucleosidase 10.6
purine nucleoside phosphorylase 10.5
methylthioadenosine phosphorylase 10.4
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Compound
6-Ethylmercaptopurine 15.5
8-Azainosine 14.5
dimethyloctanoate 13.9
C7H8N4S 13.5
6-Methylpurine 13.2
2-Azahypoxanthine 13.2
6-Methylpurine 12.9
C5H5NO 11.9
Xanthosine 11.7
3-hydroxy-2-pyrazinecarboxamide 11.6
5-methyl-cytidine 11.5
N-methyladenine 11.4
PRPP 11.2
Coformycin 11.1
2,6-DMA 10.5
Hypoxanthine 9.9
Adenine 9.4
3-methoxybenzamide 9.2
XMP 9.2
XTP 9.2
more...