Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:2.4.2.7 (
adenine phosphoribosyltransferase
)
692
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
AMP
681
hypoxanthine-guanine phosphoribosyltransferase
132
Mol
113
HPRT
57
adenosine kinase
53
adenosine deaminase
49
Sep
45
purine nucleoside phosphorylase
42
ATP
37
IMP
33
aprt
27
GMP
20
thymidine kinase
17
X-linked
16
5'-nucleotidase
16
GTP
14
hypoxanthine guanine phosphoribosyltransferase
14
xanthine oxidase
11
ADP
10
Sp1
9
more...
Disease
APRT deficiency
56
urolithiasis
50
cancer
39
Lesch-Nyhan syndrome
30
tumor
27
APRT*J
19
renal failure
16
gout
12
carcinogenesis
11
hyperuricemia
10
carcinoma
9
nephrolithiasis
8
leukemia
8
chronic renal failure
8
hepatocellular carcinoma
7
renal disease
7
AT3
6
AT3
6
AT3
6
AT3
6
more...
Symptom
starvation
6
flank pain
4
renal colic
3
pain
3
seizures
2
spasticity
2
dystonia
1
vomiting
1
dysuria
1
colic
1
diarrhea
1
muscle stiffness
1
weakness
1
Drug
-deoxyadenosine
7
Mutagen
7
Adenosine deaminase
6
TAT
4
caffeine
4
lysine
3
6-Methylpurine
2
DNase I
2
FLP
2
TTC
2
NH3
1
Dermatol
1
ACT
1
ATV
1
THF
1
Mizoribine
1
DMAP
1
Acyclovir
1
MAP
1
BLM
1
more...
Enzyme
adenine phosphoribosyltransferase
692
hypoxanthine-guanine phosphoribosyltransferase
179
adenosine deaminase
52
adenosine kinase
52
adenosine deaminase
49
purine nucleoside phosphorylase
45
thymidine kinase
17
5'-nucleotidase
17
adenine deaminase
17
xanthine phosphoribosyltransferase
14
PRPP synthetase
14
IMP dehydrogenase
12
xanthine oxidase
12
AMP deaminase
12
dihydrofolate reductase
11
amidophosphoribosyltransferase
11
phosphorylase
11
endonuclease
8
adenylate kinase
8
deaminase
8
more...
Compound
DNA
157
AMP
75
Dec
47
phosphate
41
pyrimidine
40
pyrimidine
40
ATP
38
IMP
34
Clin
34
GMP
24
Adenine
23
Adenine
22
DHA
15
DHA
15
DHA
15
adenylate
15
GTP
14
uridine
14
sodium
13
EMS
11
more...