Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
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Drug
Enzyme
Compound
Query: EC:2.4.2.7 (
adenine phosphoribosyltransferase
)
692
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Polymorphism of electrophoretic mobility of
adenine phosphoribosyltransferase
(
APRT
) was found in a population of domestic mice, Mus musculus bactrianus. The Aprt gene was mapped using two markers: plasma
esterase
1 coded by the gene Es-1 situated at the distance of 26 morgans from the centromere, and a Robertsonian translocation Rb (8.17) 1 Iem which marks the centromere. The results of linkage analysis permitted to localize the gene Aprt at 51 morgans from the centromere, and 25 morgans distal from the gene Es-1 on the genetic map of chromosome 8. It is found that emotional stress does not alter the recombination rate at chromosome 8, when spermatocytes are at the pachytene stage.
...
PMID:[Localization of the gene coding for adenine phosphoribosyltransferase on the genetic map of chromosome 8 in the mouse]. 341 35
Two electrophoretic variants of
adenine phosphoribosyltransferase
(
APRT
) were identified in a population of wild mice (Mus musculus bactrianus). Breeding tests demonstrated that the
APRT
variants are under the control of two alleles at an autosomal locus designated Aprt. We have examined the linkage relationships between Aprt and the markers of chromosome 8 including
esterase
-1 and the centromere. The recombination distance between the centromere and Aprt is 44 +/- 7 cM, and that between Es-1 and Aprt is 25 +/- 2 cM, i.e., the probable order of the markers examined is cen-Es-1-Aprt on chromosome 8.
...
PMID:Assignment of the gene for adenine phosphoribosyltransferase on the genetic map of mouse chromosome 8. 344 90
