Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:2.4.2.7 (
adenine phosphoribosyltransferase
)
692
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
To identify the proteins induced by Fe deficiency, we have compared the proteins of Fe-sufficient and Fe-deficient barley (Hordeum vulgare L.) roots by two-dimensional polyacrylamide gel electrophoresis. Peptide sequence analysis of induced proteins revealed that
formate dehydrogenase
(
FDH
),
adenine phosphoribosyltransferase
, and the lds3 gene product (for Fe deficiency-specific) increased in Fe-deficient roots.
FDH
enzyme activity was detected in Fe-deficient roots but not in Fe-sufficient roots. A cDNA encoding
FDH
(Fdh) was cloned and sequenced. Fdh expression was induced by Fe deficiency. Fdh was also expressed under anaerobic stress and its expression was more rapid than that induced by Fe deficiency. Thus, the expression of Fdh observed in Fe-deficient barley roots appeared to be a secondary effect caused by oxygen deficiency in Fe-deficient plants.
...
PMID:Formate dehydrogenase, an enzyme of anaerobic metabolism, is induced by iron deficiency in barley roots. 948 19
