Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

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Query: EC:2.4.2.30 (PARP)
13,611 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein PARP 10709 caspase-3 4192 PARP-1 2521 poly(ADP-ribose) polymerase 2366 Bcl-2 2091 ADP 1685 p53 1385 Mol 1340 caspase-9 1182 poly (ADP-ribose) polymerase 1142 cytochrome c 1087 ADP-ribosyltransferase 1021 Sep 851 NAD 847 caspase-8 790 BRCA1 697 Poly 696 p21 619 Poly(ADP-ribose) polymerase 579 annexin V 547 p38 517 ATP 487 PARP1 467 AKT 455 JNK 443 PI3K 421 ROS 412 mTOR 394 BRCA2 379 ERK 363 MAPK 363 Fas 330 PAR 313 cyclin D1 312 NAD+ 301 ERK1 282 histone 269 TNF 268 Bid 265 survivin 258 H2AX 255 Mcl-1 255 endoplasmic reticulum 248 LC3 244 ATM 238 cytochrome 234 PARP-2 231 tumor necrosis factor 205 apoptosis-inducing factor 196 p27 191 GSH 190 cytokine 186 DNA-dependent protein kinase 167 c-Jun 166 Pseudomonas 164 Bak 163 inducible nitric oxide synthase 162 XIAP 159 p65 156 RAD51 150 STAT3 149 anti-apoptotic protein 147 catalase 146 HER2 144 cyclin B1 144 PARG 143 bcl-2 143 proliferating cell nuclear antigen 143 BAX 135 proteasome 135 MMP-9 132 GTP 132 ATR 131 superoxide dismutase 131 CHOP 130 IL-6 127 PC-3 126 CDK4 125 EGFR 124 MEK 122 more...

Disease cancer 4520 tumor 2358 breast cancer 1122 tumor growth 577 ovarian cancer 551 leukemia 503 carcinoma 425 MCF 423 prostate cancer 398 hepatocellular carcinoma 353 lung cancer 347 ischemia 323 colon cancer 313 ATM 277 diabetes 259 melanoma 247 carcinogenesis 244 colorectal cancer 239 tumorigenesis 234 adenocarcinoma 218 pancreatic cancer 191 GSH 190 neuroblastoma 178 non-small cell lung cancer 175 glioma 165 gastric cancer 165 tumor progression 154 cholera 153 lymphoma 151 squamous cell carcinoma 147 stroke 141 glioblastoma 140 cervical cancer 138 epithelial ovarian cancer 135 multiple myeloma 133 acute myeloid leukemia 127 B-cell lymphoma 121 osteosarcoma 118 pertussis 117 diphtheria 109 Parkinson's disease 108 Alzheimer's disease 105 cerebral ischemia 104 liver cancer 102 metastases 93 chronic myeloid leukemia 89 DDP 81 lung carcinoma 79 liver cancer 78 acute promyelocytic leukemia 70 hyperglycemia 68 metastatic breast cancer 65 skin cancer 63 MTS 59 bladder cancer 58 chronic lymphocytic leukemia 58 AGS 57 anemia 57 retinoblastoma 57 atherosclerosis 54 oral cancer 51 renal cell carcinoma 50 myocardial infarction 49 myocardial ischemia 48 acute lymphoblastic leukemia 48 chronic lymphocytic leukemia 47 Hepatocellular carcinoma 46 heart failure 45 SDS 43 Leukemia 43 sepsis 43 colitis 43 Bordetella 42 HIV 42 Ewing's sarcoma 42 obesity 41 glioblastoma multiforme 41 sepsis 41 SCID 39 Blocking 38 more...

Symptom collapse 94 starvation 37 pain 36 diarrhea 31 fatigue 21 nausea 21 seizures 16 hypothermia 15 respiratory distress 15 functional recovery 15 hyperoxia 14 exhaustion 12 vomiting 11 weakness 10 ataxia 9 anesthesia 8 cachexia 7 headache 7 skin damage 7 Neuropathic pain 6 acute stress 5 asthenia 4 thinning 4 acidity 4 erythema 4 abdominal pain 4 menopausal symptoms 3 stigma 3 decreased appetite 3 splenomegaly 3 nausea and vomiting 3 cough 3 dyspnea 3 insomnia 2 discomfort 2 hepatomegaly 2 numbness 2 constipation 2 memory loss 2 analgesia 2 discomfort 2 stomach pain 2 pelvic pain 1 Floppy 1 Ill 1 despair 1 arthralgia 1 bradykinesia 1 neurological disability 1 tingling 1 chills 1 colic 1 HSA 1 agitation 1 hot flashes 1 tremor 1 impaired motor coordination 1 back pain 1 Welt 1 anorexia 1 eds 1 male subfertility 1 bone pain 1 Induced hypothermia 1 dry eye 1 vertigo 1 ENT 1 limb pain 1 angina 1 hypercapnia 1 overweight 1

Drug ROS 412 lysine 88 NADH 57 ascorbate 41 MAP 33 caffeine 31 vitamin E 31 IL-2 28 Arsenic trioxide 26 Monit 26 Dermatol 25 AMC 22 niacin 22 Cardiovasc 20 Taxol 20 Glycyrrhiza 19 Bortezomib 19 CED 17 IFN-gamma 17 ETS 17 NVP 17 Mutagen 16 Etoposide 16 DNase I 15 MRC 15 ADR 14 Imatinib 14 CPT-11 14 BLM 13 Sorafenib 13 CSF 13 Gel 12 Indomethacin 12 TTC 12 CTX 12 Ethanol 12 p75 12 Glutathione 12 Bevacizumab 11 Emodin 10 Emodin 10 Docetaxel 10 Adriamycin 9 Gefitinib 9 Heme 9 Herceptin 9 Asn 9 DM1 8 Parkin 8 Leaf 8 Parkin 8 ABC 7 Nitric Oxide 6 -deoxyadenosine 6 ampicillin 6 Simvastatin 6 Flavopiridol 6 PFT 6 CTX 6 CTX 6 3-Methyladenine 6 Irinotecan 6 CAM 5 Rituximab 5 ETA 5 Rosiglitazone 5 2-Methoxyestradiol 5 EE2 5 RFP 5 DHT 5 Gelatin 5 Lenalidomide 5 Dihydro 5 Oxaliplatin 5 Vitamin E 5 MDM 5 CCL 5 Lovastatin 5 ADM 5 Asthma 5 more...

Enzyme PARP 13611 caspase-3 3345 mitogen-activated protein kinase 1114 ADP-ribosyltransferase 1024 ADP-ribosyltransferase 1021 caspase-9 966 ERK 697 caspase-8 625 protein kinase 314 superoxide dismutase 188 cdc2 179 focal adhesion kinase 177 caspase-7 176 caspase-7 172 MEK 162 catalase 160 proteasome 135 topoisomerase 123 lactate dehydrogenase 123 protein kinase C 122 topoisomerase 120 caspase-1 116 AMP-activated protein kinase 115 luciferase 115 poly(ADP-ribose) glycohydrolase 101 DNA ligase 99 DNA ligase 99 AMPK 86 AMPK 79 peroxidase 76 DNA polymerase 69 GSK 62 endonuclease 62 phosphatidylinositol 3-kinase 59 MMP 56 ATPase 53 glutathione S-transferase 53 P-glycoprotein 51 NADPH oxidase 51 glutathione peroxidase 49 alanine aminotransferase 48 caspase-2 47 NADPH oxidase 46 NAD glycohydrolase 46 caspase-2 45 phospholipase C 43 ACS 42 RNA polymerase 42 NQO1 41 caspase-6 41 NO synthase 41 IKK 41 phosphoinositide 3-kinase 40 phosphodiesterase 38 trypsin 37 caspase-6 36 aspartate aminotransferase 35 adenylate cyclase 34 MAP 31 calcineurin 31 complex I 25 APC 23 creatine kinase 22 DNase 22 reverse transcriptase 22 glyceraldehyde-3-phosphate dehydrogenase 21 MPP 21 NOS 21 cathepsin B 20 DNA methyltransferase 20 nitrogenase 20 AST 17 phospholipase A2 17 acetylcholinesterase 16 prostate-specific antigen 16 glyceraldehyde-3-phosphate dehydrogenase 16 xanthine oxidase 16 venom phosphodiesterase 16 alkaline phosphatase 16 glyceraldehyde-3-phosphate dehydrogenase 15 more...

Compound DNA 5221 ADP-ribose 1867 ADP 1816 ADP 1690 ADP 1686 oxygen 1408 NAD 1135 Dec 913 NAD 847 MTT 635 ATP 487 nicotinamide 436 MDA 384 cysteine 321 PAR 313 3-aminobenzamide 289 Clin 283 TNF 268 glucose 267 calcium 257 hydrogen 240 nitric oxide 233 arginine 228 N-acetylcysteine 224 iodine 221 water 202 GSH 198 GSH 198 bromide 177 Asp 158 sodium 153 serine 147 dUTP 147 alanine 137 tyrosine 135 GTP 133 zinc 132 H2O2 126 nitrogen 122 MEK 117 phosphate 113 lysine 109 glutamate 106 DDP 104 ethanol 99 acetate 90 Panam 90 Curcumin 90 threonine 83 AMP 68 benzamide 65 acridine 65 NH2 65 urea 63 ADR 62 iron 60 Hoechst 33342 59 MTS 59 boron 58 NADH 57 Adriamycin 56 methionine 53 retinoic acid 52 Ribose 52 salt 51 cAMP 51 creatinine 50 THP 49 galactose 49 THP 49 methanol 49 ethyl acetate 48 sulfate 47 Resveratrol 47 Cytochrome c 45 cadmium 44 Cyt 44 His 44 SDS 43 ACS 42 more...

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