Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

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Query: EC:2.4.2.30 (PARP)
13,611 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein PARP 10709 caspase-3 4192 PARP-1 2521 poly(ADP-ribose) polymerase 2366 Bcl-2 2091 ADP 1685 p53 1385 Mol 1340 caspase-9 1182 poly (ADP-ribose) polymerase 1142 cytochrome c 1087 ADP-ribosyltransferase 1021 Sep 851 NAD 847 caspase-8 790 BRCA1 697 Poly 696 p21 619 Poly(ADP-ribose) polymerase 579 annexin V 547 p38 517 ATP 487 PARP1 467 AKT 455 JNK 443 PI3K 421 ROS 412 mTOR 394 BRCA2 379 MAPK 363 ERK 363 Fas 330 PAR 313 cyclin D1 312 NAD+ 301 ERK1 282 histone 269 TNF 268 Bid 265 survivin 258 more...

Disease cancer 4520 tumor 2358 breast cancer 1122 tumor growth 577 ovarian cancer 551 leukemia 503 carcinoma 425 MCF 423 prostate cancer 398 hepatocellular carcinoma 353 lung cancer 347 ischemia 323 colon cancer 313 ATM 277 diabetes 259 melanoma 247 carcinogenesis 244 colorectal cancer 239 tumorigenesis 234 adenocarcinoma 218 pancreatic cancer 191 GSH 190 neuroblastoma 178 non-small cell lung cancer 175 gastric cancer 165 glioma 165 tumor progression 154 cholera 153 lymphoma 151 squamous cell carcinoma 147 stroke 141 glioblastoma 140 cervical cancer 138 epithelial ovarian cancer 135 multiple myeloma 133 acute myeloid leukemia 127 B-cell lymphoma 121 osteosarcoma 118 pertussis 117 diphtheria 109 more...

Symptom collapse 94 starvation 37 pain 36 diarrhea 31 fatigue 21 nausea 21 seizures 16 respiratory distress 15 hypothermia 15 functional recovery 15 hyperoxia 14 exhaustion 12 vomiting 11 weakness 10 ataxia 9 anesthesia 8 headache 7 skin damage 7 cachexia 7 Neuropathic pain 6 acute stress 5 asthenia 4 thinning 4 acidity 4 erythema 4 abdominal pain 4 stigma 3 dyspnea 3 decreased appetite 3 splenomegaly 3 cough 3 nausea and vomiting 3 menopausal symptoms 3 analgesia 2 insomnia 2 discomfort 2 memory loss 2 stomach pain 2 hepatomegaly 2 numbness 2 more...

Drug ROS 412 lysine 88 NADH 57 ascorbate 41 MAP 33 vitamin E 31 caffeine 31 IL-2 28 Arsenic trioxide 26 Monit 26 Dermatol 25 AMC 22 niacin 22 Cardiovasc 20 Taxol 20 Bortezomib 19 Glycyrrhiza 19 IFN-gamma 17 ETS 17 NVP 17 CED 17 Mutagen 16 Etoposide 16 MRC 15 DNase I 15 Imatinib 14 CPT-11 14 ADR 14 Sorafenib 13 BLM 13 CSF 13 Ethanol 12 Gel 12 CTX 12 Indomethacin 12 p75 12 TTC 12 Glutathione 12 Bevacizumab 11 Emodin 10 more...

Enzyme PARP 13611 caspase-3 3345 mitogen-activated protein kinase 1114 ADP-ribosyltransferase 1024 ADP-ribosyltransferase 1021 caspase-9 966 ERK 697 caspase-8 625 protein kinase 314 superoxide dismutase 188 cdc2 179 focal adhesion kinase 177 caspase-7 176 caspase-7 172 MEK 162 catalase 160 proteasome 135 lactate dehydrogenase 123 topoisomerase 123 protein kinase C 122 topoisomerase 120 caspase-1 116 luciferase 115 AMP-activated protein kinase 115 poly(ADP-ribose) glycohydrolase 101 DNA ligase 99 DNA ligase 99 AMPK 86 AMPK 79 peroxidase 76 DNA polymerase 69 GSK 62 endonuclease 62 phosphatidylinositol 3-kinase 59 MMP 56 glutathione S-transferase 53 ATPase 53 NADPH oxidase 51 P-glycoprotein 51 glutathione peroxidase 49 more...

Compound DNA 5221 ADP-ribose 1867 ADP 1816 ADP 1690 ADP 1686 oxygen 1408 NAD 1135 Dec 913 NAD 847 MTT 635 ATP 487 nicotinamide 436 MDA 384 cysteine 321 PAR 313 3-aminobenzamide 289 Clin 283 TNF 268 glucose 267 calcium 257 hydrogen 240 nitric oxide 233 arginine 228 N-acetylcysteine 224 iodine 221 water 202 GSH 198 GSH 198 bromide 177 Asp 158 sodium 153 dUTP 147 serine 147 alanine 137 tyrosine 135 GTP 133 zinc 132 H2O2 126 nitrogen 122 MEK 117 more...

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