Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:2.4.2.30 (
PARP
)
13,611
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
PARP
10709
caspase-3
4192
PARP-1
2521
poly(ADP-ribose) polymerase
2366
Bcl-2
2091
ADP
1685
p53
1385
Mol
1340
caspase-9
1182
poly (ADP-ribose) polymerase
1142
cytochrome c
1087
ADP-ribosyltransferase
1021
Sep
851
NAD
847
caspase-8
790
BRCA1
697
Poly
696
p21
619
Poly(ADP-ribose) polymerase
579
annexin V
547
more...
Disease
cancer
4520
tumor
2358
breast cancer
1122
tumor growth
577
ovarian cancer
551
leukemia
503
carcinoma
425
MCF
423
prostate cancer
398
hepatocellular carcinoma
353
lung cancer
347
ischemia
323
colon cancer
313
ATM
277
diabetes
259
melanoma
247
carcinogenesis
244
colorectal cancer
239
tumorigenesis
234
adenocarcinoma
218
more...
Symptom
collapse
94
starvation
37
pain
36
diarrhea
31
fatigue
21
nausea
21
seizures
16
hypothermia
15
respiratory distress
15
functional recovery
15
hyperoxia
14
exhaustion
12
vomiting
11
weakness
10
ataxia
9
anesthesia
8
skin damage
7
cachexia
7
headache
7
Neuropathic pain
6
more...
Drug
ROS
412
lysine
88
NADH
57
ascorbate
41
MAP
33
caffeine
31
vitamin E
31
IL-2
28
Monit
26
Arsenic trioxide
26
Dermatol
25
AMC
22
niacin
22
Taxol
20
Cardiovasc
20
Bortezomib
19
Glycyrrhiza
19
IFN-gamma
17
NVP
17
ETS
17
more...
Enzyme
PARP
13611
caspase-3
3345
mitogen-activated protein kinase
1114
ADP-ribosyltransferase
1024
ADP-ribosyltransferase
1021
caspase-9
966
ERK
697
caspase-8
625
protein kinase
314
superoxide dismutase
188
cdc2
179
focal adhesion kinase
177
caspase-7
176
caspase-7
172
MEK
162
catalase
160
proteasome
135
topoisomerase
123
lactate dehydrogenase
123
protein kinase C
122
more...
Compound
DNA
5221
ADP-ribose
1867
ADP
1816
ADP
1690
ADP
1686
oxygen
1408
NAD
1135
Dec
913
NAD
847
MTT
635
ATP
487
nicotinamide
436
MDA
384
cysteine
321
PAR
313
3-aminobenzamide
289
Clin
283
TNF
268
glucose
267
calcium
257
more...