Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:2.4.1.14 (SPS)
 813 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Oxidation of the square planar Rh(I) complex [Rh(SPS(Me))(PPh3)] (SPS(Me) = 1-methyl-1-P-2.6-bis(diphenylphosphinosulfide)-3,5-(bisphenyl)-phosphinine) (1) based on mixed SPS-pincer ligand with hexachloroethane yielded the Rh(III) dichloride complex [Rh(SPS(Me))(PPh3)Cl2] (2), which was structurally characterized. The homoleptic Rh(III) complex [Rh(SPS(Me))2][Cl] (4) was obtained via the stoichiometric reaction of SPS(Me) anion (3) with [Rh(tht)3Cl3] (tht = tetrahydrothiophene). Complex 4, which was characterized by X-ray diffraction, was also studied by cyclic voltammetry. Complex 4 can be reversibly reduced at E = -1.16 V (vs SCE) to give the neutral 19-electron Rh(II) complex [Rh(SPS(Me))2] (5). Accordingly, complex 5 could be synthesized via chemical reduction of 4 with zinc dust. EPR spectra of complex 5 were obtained after electrochemical or chemical reduction of 4 in THF or CH2Cl2. Hyperfine interaction with two equivalent 31P nuclei was observed in liquid solution, while an additional coupling with a spin 1/2 nucleus, probably 103Rh, was detected in frozen solution. The 31P couplings are consistent with DFT calculations that predict a drastic increase in the axial P-S bond lengths when reducing (SPS(Me))2Rh(III). In the reduced complex, the unpaired electron is mainly localized in a rhodium d(z2) orbital, consistent with the g-anisotropy measured at 100 K.
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PMID:Synthesis and X-ray crystal structure of a cationic homoleptic (SPS)2Rh(III) complex and EPR study of its reduction process. 1585 97

Reactions of Ln(BH4)3(THF)n and [Li(Et2O)]SPS(Me)], the lithium salt of an anionic SPS pincer ligand composed of a central hypervalent lambda4-phosphinine ring bearing two ortho-positioned diphenylphosphine sulfide sidearms, led to the monosubstituted compounds [Ln(BH4)2(SPS(Me))(THF)2] [Ln = Ce (1), Nd (2)], while the homoleptic complexes [Ln(SPS(Me))3] [Ln = Ce (3), Nd (4)] were obtained by treatment of LnX3 (X = I, BH4) with [K(Et2O)][SPS(Me)]. The [UX2(SPS(Me))2] complexes [X = Cl (5), BH4 (6)] were isolated from reactions of UX4 and the lithium or potassium salt of the [SPS(Me)]- anion. The X-ray crystal structures of 1.1.5THF, 2.1.5THF, 3.2THF.2Et2O, and 5.4py reveal that the flexible tridentate [SPS(Me)]- anion is bound to the metal as a tertiary phosphine with electronic delocalization within the unsaturated parts of the ligand.
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PMID:Lanthanide and uranium complexes with an SPS-based pincer ligand. 1711 89