Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:2.3.3.1 (
citrate synthase
)
4,488
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
citrate synthase
4253
lactate dehydrogenase
552
ATP
443
malate dehydrogenase
345
Mol
335
Sep
290
insulin
287
hexokinase
266
cytochrome c oxidase
255
phosphofructokinase
247
isocitrate dehydrogenase
216
NADH
213
pyruvate kinase
171
PGC
145
ATPase
143
aconitase
138
Citrate synthase
137
creatine kinase
135
catalase
124
pyruvate dehydrogenase
121
superoxide dismutase
120
ADP
113
3-hydroxyacyl-CoA dehydrogenase
98
NAD
95
TCA
91
myosin heavy chain
91
cytochrome c
89
glutamate dehydrogenase
87
fumarase
86
glucose-6-phosphate dehydrogenase
81
cytochrome
79
aspartate aminotransferase
78
peroxisome proliferator-activated receptor
76
pyruvate carboxylase
69
LDH
67
AMP
67
myosin
62
glutathione peroxidase
59
peroxisome proliferator-activated receptor gamma
57
membrane protein
53
NMR
52
alpha-ketoglutarate dehydrogenase
52
HAD
51
heat shock protein
51
myoglobin
49
AMPK
48
CO2
48
NADP
46
crystallin
44
AMP-activated protein kinase
44
acyl-CoA dehydrogenase
44
mitochondrial transcription factor A
43
GLUT4
43
phosphoenolpyruvate carboxylase
42
fatty acid synthase
42
NAD+
41
glucose transporter
41
endoplasmic reticulum
40
carnitine palmitoyltransferase
40
reductase
39
glycogen phosphorylase
38
TFAM
38
COX
37
dimeric
37
cardiac muscle
37
glycolytic enzyme
36
ATP synthase
35
hemoglobin
34
SDS
34
Pseudomonas
33
alcohol dehydrogenase
32
NADPH
32
AED
32
pyruvate dehydrogenase complex
31
phosphoenolpyruvate carboxykinase
31
CD36
31
polypeptide
30
alanine aminotransferase
30
GLUT-4
30
UCP3
30
more...
Disease
obesity
110
cold
95
diabetes
94
spotted fever
69
heart failure
48
type 2 diabetes
45
cancer
43
ischemia
43
SDS
34
GSH
29
myopathy
28
tumor
27
Alzheimer's disease
24
depression
23
typhus
22
stroke
22
chronic obstructive pulmonary disease
21
Parkinson's disease
19
hyperglycemia
17
muscular atrophy
17
fatty liver
16
rickettsiosis
16
mitochondrial disease
16
Evans
16
myocardial infarction
16
Mycobacterium
16
ventricular hypertrophy
15
bartonellosis
15
hypertension
15
Brown
15
cardiomyopathy
13
tuberculosis
13
hyperthyroidism
13
amyotrophic lateral sclerosis
13
glucose intolerance
13
hyperinsulinemia
12
hypothyroidism
12
lactic acidosis
12
endocarditis
12
sepsis
11
cardiovascular disease
11
sepsis
10
heart disease
10
encephalopathy
10
malnutrition
10
Huntington's disease
9
FAS
9
Duchenne muscular dystrophy
9
mitochondrial myopathy
9
bipolar disorder
9
bacteremia
9
dehydration
9
ACP
9
infectious diseases
9
wasting
8
Leigh syndrome
8
OPA1
8
immunodeficiency
8
anemia
8
Mycoplasma
8
iron deficiency
8
myocardial ischemia
8
metabolic syndrome
8
HIV
8
pheochromocytoma
8
epilepsy
8
Friedreich's ataxia
8
Diaphragm
7
carcinoma
7
dilated cardiomyopathy
7
congestive heart failure
7
neuroblastoma
7
NAME
7
SEM
7
neuropathy
6
Infection
6
PCC
6
Kearns-Sayre syndrome
6
carcinogenesis
6
hypoglycemia
6
more...
Symptom
fatigue
78
exhaustion
55
weakness
25
starvation
24
seizures
12
overweight
11
cachexia
9
hyperoxia
7
functional recovery
7
ataxia
6
pain
6
hypothermia
5
hepatomegaly
5
anesthesia
5
acidity
5
myalgia
5
hypotonia
5
ophthalmoplegia
4
hypercapnia
4
headache
4
agitation
3
tremor
3
acute stress
3
loss of equilibrium
2
Tenderness
2
chorea
2
anorexia
2
dyspnea
2
spasticity
2
lethargy
2
vomiting
2
collapse
2
fever of unknown origin
2
arthralgia
2
nausea
1
physical exhaustion
1
Exercise intolerance
1
muscle stiffness
1
male subfertility
1
cyanosis
1
ataxic gait
1
diarrhea
1
thinning
1
Extrapyramidal symptoms
1
DNA marker
1
erythema
1
Diaphragmatic weakness
1
pallor
1
low back pain
1
paresis
1
spasm
1
pelvic pain
1
Fatigability
1
nasal discharge
1
Deafferentation
1
abdominal pain
1
angina
1
Catch
1
Drug
NADH
215
citric acid
158
lysine
32
ROS
24
Asn
12
ascorbate
11
Gel
10
vitamin E
9
Leaf
8
Parkin
7
Cardiovasc
7
Parkin
7
VCR
6
Glutathione
6
lactose
5
Citric acid
4
FAD
4
DNase I
4
Clofibrate
3
Ethanol
3
Growth hormone
3
Portal
3
caffeine
3
Growth hormone
3
L-tyrosine
3
Captopril
2
CMX
2
Biopolymers
2
Nitric Oxide
2
AZT
2
EPI
2
Fructose
2
NH3
2
CAM
2
Papaverine
2
EPA
2
Rosiglitazone
2
Adenosine triphosphate
2
ETS
2
Kenyan
2
AZT
2
Perindopril
2
Coral
2
PTH
2
Naftidrofuryl
2
Simvastatin
2
CSI
2
ETA
1
Alanine
1
Tao
1
Photofrin
1
Dermatol
1
CEX
1
MAP
1
Haloperidol Decanoate
1
EE2
1
RBT
1
Fluorescein
1
Cytidine
1
Oxfenicine
1
Cimaterol
1
Artesunate
1
Mutagen
1
Fulvestrant
1
Check
1
Monit
1
ddI
1
Protein hydrolysate
1
Acacia
1
K-252a
1
ISP
1
Colombo
1
Ginseng
1
CaCl2
1
Bayer
1
TMS
1
ABC
1
TMX
1
Rasburicase
1
Bezafibrate
1
more...
Enzyme
citrate synthase
4488
lactate dehydrogenase
572
malate dehydrogenase
369
succinate dehydrogenase
328
cytochrome oxidase
281
hexokinase
266
phosphofructokinase
265
isocitrate dehydrogenase
235
isocitrate dehydrogenase
233
ATPase
177
pyruvate kinase
171
complex I
166
3-hydroxyacyl-CoA dehydrogenase
157
aconitase
156
creatine kinase
154
pyruvate dehydrogenase
150
condensing enzyme
148
3-hydroxyacyl-CoA dehydrogenase
144
superoxide dismutase
135
catalase
127
pyruvate dehydrogenase
120
pyruvate dehydrogenase
120
alpha-ketoglutarate dehydrogenase
111
glucose-6-phosphate dehydrogenase
99
fumarase
95
AMP-activated protein kinase
88
glutamate dehydrogenase
87
glutamate dehydrogenase
87
glutamate dehydrogenase
87
diaphorase
80
phosphorylase
80
aspartate aminotransferase
79
phosphoenolpyruvate carboxykinase
76
phosphoenolpyruvate carboxykinase
75
phosphoenolpyruvate carboxykinase
75
pyruvate carboxylase
71
acyl-CoA dehydrogenase
68
CPT
67
CPR
61
glutathione peroxidase
60
glyceraldehyde-3-phosphate dehydrogenase
56
glyceraldehyde-3-phosphate dehydrogenase
55
malate synthase
51
AMPK
49
AMPK
48
phosphoenolpyruvate carboxylase
47
isocitrate lyase
46
glyceraldehyde-3-phosphate dehydrogenase
45
acyl-CoA dehydrogenase
44
glycerol-3-phosphate dehydrogenase
42
glycerol-3-phosphate dehydrogenase
42
alanine aminotransferase
42
glyceraldehyde-3-phosphate dehydrogenase
41
ATP synthase
40
alcohol dehydrogenase
34
adenylate kinase
33
succinic dehydrogenase
32
acetyl-CoA carboxylase
29
aldolase
29
carnitine acetyltransferase
28
glyceraldehyde-3-phosphate dehydrogenase
27
citrate lyase
27
luciferase
27
diaphorase
26
ACS
25
RNA polymerase
25
oxoglutarate dehydrogenase
25
protein kinase
24
chaperonin
24
glutaminase
23
SCS
23
lipoprotein lipase
22
glutamine synthetase
22
succinyl-CoA synthetase
22
glutathione reductase
21
beta-hydroxybutyrate dehydrogenase
20
acyl-CoA synthetase
20
FabH
20
6-phosphogluconate dehydrogenase
19
mitogen-activated protein kinase
19
more...
Compound
glucose
634
oxygen
523
ATP
443
DNA
438
CoA
390
Dec
348
acetyl-CoA
217
NADH
215
phosphate
184
glutamate
184
acetate
164
water
157
2-oxoglutarate
138
NAD
134
ADP
123
Clin
117
ADP
114
ADP
113
NAD
95
TCA
94
calcium
92
sodium
83
nitrogen
80
alanine
77
AMP
73
NADP
69
CO2
65
hydrogen
64
glutamine
61
glycerol
60
arginine
57
isocitrate
57
iron
51
phosphocreatine
48
serine
47
cysteine
44
ethanol
43
oxalacetate
42
urea
42
leucine
41
lysine
40
nicotinamide
39
His
39
CIT
38
SDS
38
salt
37
COX
37
Lactate
37
Cardiol
36
nitric oxide
36
NADPH
34
GSH
33
GSH
33
Insulin
33
NADPH
32
alcohol dehydrogenase
32
ammonium
32
pentose
31
pentose
31
pentose
31
palmitoyl-CoA
31
pentose
31
ammonia
31
acetic acid
29
methionine
27
sulfate
26
Asp
26
malonyl-CoA
25
L-carnitine
25
copper
25
H2O2
24
succinic acid
24
proline
23
glucose-6-phosphate
22
aluminum
20
Glycogen
20
malic acid
20
Phe
20
Mg2+
19
aspartic acid
19
more...