Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:2.3.3.1 (citrate synthase)
4,488 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
citrate synthase 4253
lactate dehydrogenase 552
ATP 443
malate dehydrogenase 345
Mol 335
Sep 290
insulin 287
hexokinase 266
cytochrome c oxidase 255
phosphofructokinase 247
isocitrate dehydrogenase 216
NADH 213
pyruvate kinase 171
PGC 145
ATPase 143
aconitase 138
Citrate synthase 137
creatine kinase 135
catalase 124
pyruvate dehydrogenase 121
superoxide dismutase 120
ADP 113
3-hydroxyacyl-CoA dehydrogenase 98
NAD 95
TCA 91
myosin heavy chain 91
cytochrome c 89
glutamate dehydrogenase 87
fumarase 86
glucose-6-phosphate dehydrogenase 81
cytochrome 79
aspartate aminotransferase 78
peroxisome proliferator-activated receptor 76
pyruvate carboxylase 69
LDH 67
AMP 67
myosin 62
glutathione peroxidase 59
peroxisome proliferator-activated receptor gamma 57
membrane protein 53
NMR 52
alpha-ketoglutarate dehydrogenase 52
HAD 51
heat shock protein 51
myoglobin 49
AMPK 48
CO2 48
NADP 46
crystallin 44
AMP-activated protein kinase 44
acyl-CoA dehydrogenase 44
mitochondrial transcription factor A 43
GLUT4 43
phosphoenolpyruvate carboxylase 42
fatty acid synthase 42
NAD+ 41
glucose transporter 41
endoplasmic reticulum 40
carnitine palmitoyltransferase 40
reductase 39
glycogen phosphorylase 38
TFAM 38
COX 37
dimeric 37
cardiac muscle 37
glycolytic enzyme 36
ATP synthase 35
hemoglobin 34
SDS 34
Pseudomonas 33
alcohol dehydrogenase 32
NADPH 32
AED 32
pyruvate dehydrogenase complex 31
phosphoenolpyruvate carboxykinase 31
CD36 31
polypeptide 30
alanine aminotransferase 30
GLUT-4 30
UCP3 30
more...
Disease
obesity 110
cold 95
diabetes 94
spotted fever 69
heart failure 48
type 2 diabetes 45
cancer 43
ischemia 43
SDS 34
GSH 29
myopathy 28
tumor 27
Alzheimer's disease 24
depression 23
typhus 22
stroke 22
chronic obstructive pulmonary disease 21
Parkinson's disease 19
hyperglycemia 17
muscular atrophy 17
fatty liver 16
rickettsiosis 16
mitochondrial disease 16
Evans 16
myocardial infarction 16
Mycobacterium 16
ventricular hypertrophy 15
bartonellosis 15
hypertension 15
Brown 15
cardiomyopathy 13
tuberculosis 13
hyperthyroidism 13
amyotrophic lateral sclerosis 13
glucose intolerance 13
hyperinsulinemia 12
hypothyroidism 12
lactic acidosis 12
endocarditis 12
sepsis 11
cardiovascular disease 11
sepsis 10
heart disease 10
encephalopathy 10
malnutrition 10
Huntington's disease 9
FAS 9
Duchenne muscular dystrophy 9
mitochondrial myopathy 9
bipolar disorder 9
bacteremia 9
dehydration 9
ACP 9
infectious diseases 9
wasting 8
Leigh syndrome 8
OPA1 8
immunodeficiency 8
anemia 8
Mycoplasma 8
iron deficiency 8
myocardial ischemia 8
metabolic syndrome 8
HIV 8
pheochromocytoma 8
epilepsy 8
Friedreich's ataxia 8
Diaphragm 7
carcinoma 7
dilated cardiomyopathy 7
congestive heart failure 7
neuroblastoma 7
NAME 7
SEM 7
neuropathy 6
Infection 6
PCC 6
Kearns-Sayre syndrome 6
carcinogenesis 6
hypoglycemia 6
more...
Symptom
fatigue 78
exhaustion 55
weakness 25
starvation 24
seizures 12
overweight 11
cachexia 9
hyperoxia 7
functional recovery 7
ataxia 6
pain 6
hypothermia 5
hepatomegaly 5
anesthesia 5
acidity 5
myalgia 5
hypotonia 5
ophthalmoplegia 4
hypercapnia 4
headache 4
agitation 3
tremor 3
acute stress 3
loss of equilibrium 2
Tenderness 2
chorea 2
anorexia 2
dyspnea 2
spasticity 2
lethargy 2
vomiting 2
collapse 2
fever of unknown origin 2
arthralgia 2
nausea 1
physical exhaustion 1
Exercise intolerance 1
muscle stiffness 1
male subfertility 1
cyanosis 1
ataxic gait 1
diarrhea 1
thinning 1
Extrapyramidal symptoms 1
DNA marker 1
erythema 1
Diaphragmatic weakness 1
pallor 1
low back pain 1
paresis 1
spasm 1
pelvic pain 1
Fatigability 1
nasal discharge 1
Deafferentation 1
abdominal pain 1
angina 1
Catch 1
Drug
NADH 215
citric acid 158
lysine 32
ROS 24
Asn 12
ascorbate 11
Gel 10
vitamin E 9
Leaf 8
Parkin 7
Cardiovasc 7
Parkin 7
VCR 6
Glutathione 6
lactose 5
Citric acid 4
FAD 4
DNase I 4
Clofibrate 3
Ethanol 3
Growth hormone 3
Portal 3
caffeine 3
Growth hormone 3
L-tyrosine 3
Captopril 2
CMX 2
Biopolymers 2
Nitric Oxide 2
AZT 2
EPI 2
Fructose 2
NH3 2
CAM 2
Papaverine 2
EPA 2
Rosiglitazone 2
Adenosine triphosphate 2
ETS 2
Kenyan 2
AZT 2
Perindopril 2
Coral 2
PTH 2
Naftidrofuryl 2
Simvastatin 2
CSI 2
ETA 1
Alanine 1
Tao 1
Photofrin 1
Dermatol 1
CEX 1
MAP 1
Haloperidol Decanoate 1
EE2 1
RBT 1
Fluorescein 1
Cytidine 1
Oxfenicine 1
Cimaterol 1
Artesunate 1
Mutagen 1
Fulvestrant 1
Check 1
Monit 1
ddI 1
Protein hydrolysate 1
Acacia 1
K-252a 1
ISP 1
Colombo 1
Ginseng 1
CaCl2 1
Bayer 1
TMS 1
ABC 1
TMX 1
Rasburicase 1
Bezafibrate 1
more...
Enzyme
citrate synthase 4488
lactate dehydrogenase 572
malate dehydrogenase 369
succinate dehydrogenase 328
cytochrome oxidase 281
hexokinase 266
phosphofructokinase 265
isocitrate dehydrogenase 235
isocitrate dehydrogenase 233
ATPase 177
pyruvate kinase 171
complex I 166
3-hydroxyacyl-CoA dehydrogenase 157
aconitase 156
creatine kinase 154
pyruvate dehydrogenase 150
condensing enzyme 148
3-hydroxyacyl-CoA dehydrogenase 144
superoxide dismutase 135
catalase 127
pyruvate dehydrogenase 120
pyruvate dehydrogenase 120
alpha-ketoglutarate dehydrogenase 111
glucose-6-phosphate dehydrogenase 99
fumarase 95
AMP-activated protein kinase 88
glutamate dehydrogenase 87
glutamate dehydrogenase 87
glutamate dehydrogenase 87
diaphorase 80
phosphorylase 80
aspartate aminotransferase 79
phosphoenolpyruvate carboxykinase 76
phosphoenolpyruvate carboxykinase 75
phosphoenolpyruvate carboxykinase 75
pyruvate carboxylase 71
acyl-CoA dehydrogenase 68
CPT 67
CPR 61
glutathione peroxidase 60
glyceraldehyde-3-phosphate dehydrogenase 56
glyceraldehyde-3-phosphate dehydrogenase 55
malate synthase 51
AMPK 49
AMPK 48
phosphoenolpyruvate carboxylase 47
isocitrate lyase 46
glyceraldehyde-3-phosphate dehydrogenase 45
acyl-CoA dehydrogenase 44
glycerol-3-phosphate dehydrogenase 42
glycerol-3-phosphate dehydrogenase 42
alanine aminotransferase 42
glyceraldehyde-3-phosphate dehydrogenase 41
ATP synthase 40
alcohol dehydrogenase 34
adenylate kinase 33
succinic dehydrogenase 32
acetyl-CoA carboxylase 29
aldolase 29
carnitine acetyltransferase 28
glyceraldehyde-3-phosphate dehydrogenase 27
citrate lyase 27
luciferase 27
diaphorase 26
ACS 25
RNA polymerase 25
oxoglutarate dehydrogenase 25
protein kinase 24
chaperonin 24
glutaminase 23
SCS 23
lipoprotein lipase 22
glutamine synthetase 22
succinyl-CoA synthetase 22
glutathione reductase 21
beta-hydroxybutyrate dehydrogenase 20
acyl-CoA synthetase 20
FabH 20
6-phosphogluconate dehydrogenase 19
mitogen-activated protein kinase 19
more...
Compound
glucose 634
oxygen 523
ATP 443
DNA 438
CoA 390
Dec 348
acetyl-CoA 217
NADH 215
phosphate 184
glutamate 184
acetate 164
water 157
2-oxoglutarate 138
NAD 134
ADP 123
Clin 117
ADP 114
ADP 113
NAD 95
TCA 94
calcium 92
sodium 83
nitrogen 80
alanine 77
AMP 73
NADP 69
CO2 65
hydrogen 64
glutamine 61
glycerol 60
arginine 57
isocitrate 57
iron 51
phosphocreatine 48
serine 47
cysteine 44
ethanol 43
oxalacetate 42
urea 42
leucine 41
lysine 40
nicotinamide 39
His 39
CIT 38
SDS 38
salt 37
COX 37
Lactate 37
Cardiol 36
nitric oxide 36
NADPH 34
GSH 33
GSH 33
Insulin 33
NADPH 32
alcohol dehydrogenase 32
ammonium 32
pentose 31
pentose 31
pentose 31
palmitoyl-CoA 31
pentose 31
ammonia 31
acetic acid 29
methionine 27
sulfate 26
Asp 26
malonyl-CoA 25
L-carnitine 25
copper 25
H2O2 24
succinic acid 24
proline 23
glucose-6-phosphate 22
aluminum 20
Glycogen 20
malic acid 20
Phe 20
Mg2+ 19
aspartic acid 19
more...