Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:2.3.3.1 (
citrate synthase
)
4,488
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
citrate synthase
4253
lactate dehydrogenase
552
ATP
443
malate dehydrogenase
345
Mol
335
Sep
290
insulin
287
hexokinase
266
cytochrome c oxidase
255
phosphofructokinase
247
isocitrate dehydrogenase
216
NADH
213
pyruvate kinase
171
PGC
145
ATPase
143
aconitase
138
Citrate synthase
137
creatine kinase
135
catalase
124
pyruvate dehydrogenase
121
superoxide dismutase
120
ADP
113
3-hydroxyacyl-CoA dehydrogenase
98
NAD
95
TCA
91
myosin heavy chain
91
cytochrome c
89
glutamate dehydrogenase
87
fumarase
86
glucose-6-phosphate dehydrogenase
81
cytochrome
79
aspartate aminotransferase
78
peroxisome proliferator-activated receptor
76
pyruvate carboxylase
69
LDH
67
AMP
67
myosin
62
glutathione peroxidase
59
peroxisome proliferator-activated receptor gamma
57
membrane protein
53
more...
Disease
obesity
110
cold
95
diabetes
94
spotted fever
69
heart failure
48
type 2 diabetes
45
cancer
43
ischemia
43
SDS
34
GSH
29
myopathy
28
tumor
27
Alzheimer's disease
24
depression
23
typhus
22
stroke
22
chronic obstructive pulmonary disease
21
Parkinson's disease
19
hyperglycemia
17
muscular atrophy
17
Mycobacterium
16
mitochondrial disease
16
Evans
16
rickettsiosis
16
myocardial infarction
16
fatty liver
16
ventricular hypertrophy
15
Brown
15
hypertension
15
bartonellosis
15
glucose intolerance
13
tuberculosis
13
amyotrophic lateral sclerosis
13
cardiomyopathy
13
hyperthyroidism
13
hyperinsulinemia
12
hypothyroidism
12
lactic acidosis
12
endocarditis
12
sepsis
11
more...
Symptom
fatigue
78
exhaustion
55
weakness
25
starvation
24
seizures
12
overweight
11
cachexia
9
functional recovery
7
hyperoxia
7
ataxia
6
pain
6
hypothermia
5
anesthesia
5
acidity
5
hepatomegaly
5
hypotonia
5
myalgia
5
ophthalmoplegia
4
hypercapnia
4
headache
4
agitation
3
tremor
3
acute stress
3
loss of equilibrium
2
Tenderness
2
chorea
2
fever of unknown origin
2
anorexia
2
spasticity
2
lethargy
2
dyspnea
2
vomiting
2
collapse
2
arthralgia
2
nausea
1
physical exhaustion
1
Exercise intolerance
1
muscle stiffness
1
male subfertility
1
ataxic gait
1
more...
Drug
NADH
215
citric acid
158
lysine
32
ROS
24
Asn
12
ascorbate
11
Gel
10
vitamin E
9
Leaf
8
Parkin
7
Cardiovasc
7
Parkin
7
VCR
6
Glutathione
6
lactose
5
DNase I
4
Citric acid
4
FAD
4
Clofibrate
3
Ethanol
3
Growth hormone
3
Portal
3
Growth hormone
3
caffeine
3
L-tyrosine
3
NH3
2
CMX
2
EPI
2
Simvastatin
2
Nitric Oxide
2
AZT
2
Biopolymers
2
Fructose
2
CAM
2
Papaverine
2
Kenyan
2
Naftidrofuryl
2
Adenosine triphosphate
2
Rosiglitazone
2
ETS
2
more...
Enzyme
citrate synthase
4488
lactate dehydrogenase
572
malate dehydrogenase
369
succinate dehydrogenase
328
cytochrome oxidase
281
hexokinase
266
phosphofructokinase
265
isocitrate dehydrogenase
235
isocitrate dehydrogenase
233
ATPase
177
pyruvate kinase
171
complex I
166
3-hydroxyacyl-CoA dehydrogenase
157
aconitase
156
creatine kinase
154
pyruvate dehydrogenase
150
condensing enzyme
148
3-hydroxyacyl-CoA dehydrogenase
144
superoxide dismutase
135
catalase
127
pyruvate dehydrogenase
120
pyruvate dehydrogenase
120
alpha-ketoglutarate dehydrogenase
111
glucose-6-phosphate dehydrogenase
99
fumarase
95
AMP-activated protein kinase
88
glutamate dehydrogenase
87
glutamate dehydrogenase
87
glutamate dehydrogenase
87
phosphorylase
80
diaphorase
80
aspartate aminotransferase
79
phosphoenolpyruvate carboxykinase
76
phosphoenolpyruvate carboxykinase
75
phosphoenolpyruvate carboxykinase
75
pyruvate carboxylase
71
acyl-CoA dehydrogenase
68
CPT
67
CPR
61
glutathione peroxidase
60
more...
Compound
glucose
634
oxygen
523
ATP
443
DNA
438
CoA
390
Dec
348
acetyl-CoA
217
NADH
215
phosphate
184
glutamate
184
acetate
164
water
157
2-oxoglutarate
138
NAD
134
ADP
123
Clin
117
ADP
114
ADP
113
NAD
95
TCA
94
calcium
92
sodium
83
nitrogen
80
alanine
77
AMP
73
NADP
69
CO2
65
hydrogen
64
glutamine
61
glycerol
60
isocitrate
57
arginine
57
iron
51
phosphocreatine
48
serine
47
cysteine
44
ethanol
43
urea
42
oxalacetate
42
leucine
41
more...