Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:2.3.3.1 (citrate synthase)
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Human Gene/Protein
citrate synthase 12.8
mitochondrial ribosomal protein L48 12.8
MO25 protein 12.8
pentatricopeptide repeat domain 3 11.8
URK1 11.8
METTL12 11.8
Calcineurin catalytic subunit 11.8
NADH dehydrogenase flavoprotein 1 11.8
Citrate synthase 11.5
ATP synthase D chain, mitochondrial 11.2
myosin-Ic 10.8
pyruvate carboxylase, mitochondrial 10.8
ACTIN-2 10.8
SDHA protein 10.8
collagen, type IV, alpha 1 10.5
ATP5J2 10.5
3-hydroxyacyl-CoA dehydrogenase 10.3
Myokinase 10.2
CCL11 protein 10.2
PFK-P 10.2
more...
Disease
Citrate toxicity 10.8
HPLE 10.2
Steroid-induced diabetes 10.2
North Asian tick typhus 9.3
CIIP 9.0
spotted fever 8.5
bartonellosis 8.3
Richner-Hanhart syndrome 8.2
Brazilian spotted fever 8.1
mite-borne 8.0
Ehrlichia canis infection 7.9
Murine typhus 7.7
Muscle degeneration 7.6
MGA3 7.6
rickettsiosis 7.2
typhus 7.1
Mitochondrial DNA depletion 7.0
Klebs 7.0
KCS 7.0
Bladder outlet obstruction 6.7
more...
Symptom
Diaphragmatic weakness 8.5
Fatigability 6.8
loss of equilibrium 6.7
Exercise intolerance 5.9
physical exhaustion 5.4
Deafferentation 5.4
Tenderness 5.2
Extrapyramidal symptoms 5.2
exhaustion 4.8
male subfertility 4.7
Catch 3.8
ataxic gait 3.7
cachexia 3.5
fatigue 3.4
hyperoxia 3.3
ophthalmoplegia 3.1
DNA marker 2.9
starvation 2.8
fever of unknown origin 2.8
chorea 2.8
more...
Drug
Haloperidol Decanoate 10.2
Oxfenicine 8.4
Protein hydrolysate 7.9
Naftidrofuryl 7.5
Cimaterol 7.4
Amlexanox 7.3
Activase 7.2
CMX 7.0
Atabrine 6.9
citric acid 6.8
Trifluoroethanol 6.5
TMX 6.5
3,4-Dihydroxyphenylalanine 6.5
NADH 6.1
Citric acid 5.8
CEX 5.7
RBT 5.6
Perindopril 5.4
3-Methyladenine 5.4
Clofibrate 5.2
more...
Enzyme
citrate synthase 12.8
oleate Delta12-hydroxylase 12.8
condensing enzyme 11.9
citryl-CoA lyase 11.7
calpain A 11.2
PEP phosphatase 11.0
citrate lyase deacetylase 10.8
3-hydroxyacyl-CoA dehydrogenase 10.7
3-hydroxyacyl-CoA dehydrogenase 10.5
CimA 10.5
citryl-CoA synthetase 10.5
calpain B 10.2
trans-2-enoyl-CoA reductase 10.1
oxoglutarate dehydrogenase 10.1
citramalate synthase 10.0
glycerophosphate phosphatase 10.0
strombine dehydrogenase 9.8
FabF 9.8
2-oxoglutarate decarboxylase 9.5
malate synthase 9.5
more...
Compound
Trifluoroacetonylmercaptoethanol 12.8
Ubisemiquinone 11.8
2,4-Dihydroxyquinoline 11.2
Citramalate 10.8
Citramalate 10.8
Methylcitric acid 10.7
Ethylmalonic acid 10.5
T 78 10.5
Mersalyl acid 10.0
Thiolactomycin 9.9
malyl-CoA 9.6
C4H6O6 9.3
2-methylcitric acid 9.2
ethyl 3,4-dihydroxybenzoate 9.0
2,3-naphthalenediol 8.9
PDAP 8.9
MB 1 8.8
propionyl-coenzyme A 8.7
oxalacetate 8.6
2-keto-4-hydroxyglutarate 8.6
more...