Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: EC:2.3.3.1 (citrate synthase)
 4,488 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The effects of electrically induced dynamic muscle contractions on muscle endurance, strength, morphology and enzymatic adaptation were studied in seven male physical education students. The training program consisted of electrically induced one-leg extensions on a modified Krogh cycle with a 30-Watt (W) load for 60 min, 3 times a week for 4 weeks. Muscle fiber type composition was unchanged, but diffusional capacity was increased after electromyostimulation training. The endurance capacity in the trained leg increased by 82% (p < 0.01), but there were no significant changes in citrate synthase, phosphofructokinase activities, and carbonic anhydrase III and myoglobin contents, suggesting that neural adaptation and learning were more important factors for the increased endurance capacity than enzymatic adaptation. Prolyl 4-hydroxylase activity, a marker of collagen biosynthesis, increased 3-fold (p < 0.01) as a result of the training. This could be due to muscle damage caused by electrically induced muscle contractions. In conclusion, electrically induced dynamic muscle contractions can increase muscle endurance without clear concominant changes in muscle morphologic and enzymatic adaptation. Increased prolyl 4-hydroxylase activity could suggest muscle damage caused by electrically induced muscle contractions.
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PMID:Training effects of electrically induced dynamic contractions in human quadriceps muscle. 766 36