Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:2.3.1.21 (CPT)
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Human Gene/Protein
carnitine palmitoyltransferase I 12.8
CPT 12.8
transducin-like enhancer protein 12.8
carnitine palmitoyltransferase 12.7
CPT I 12.3
CPT II 12.3
Carnitine palmitoyltransferase I 11.8
Carnitine O-palmitoyltransferase 11.8
IKBB 11.8
acyl-Coenzyme A oxidase 2, branched chain 11.8
CATL1 11.8
NADH dehydrogenase flavoprotein 1 11.8
Cell death activator 11.8
CPT2 11.3
CPTI-M 11.2
TYKi 11.2
enoyl-Coenzyme A, hydratase/3-hydroxyacyl Coenzyme A dehydrogenase 10.8
jun B proto-oncogene 10.8
cell death-inducing DFFA-like effector a 10.8
suppressor of cytokine signalling protein 10.8
CPTI 10.7
CPT1B 10.6
LCAD 10.5
ubiquinol-cytochrome c reductase binding protein 10.4
acyl-CoA thioesterase 1 10.4
TSARG7 10.4
Distal-less homeobox 5 10.4
TMLH 10.4
IHPK2 10.4
CPT1 10.4
CPT1C 10.4
carnitine acetyltransferase 10.3
CROCC 10.2
actin, alpha 2, smooth muscle, aorta 10.2
ENaCbeta 10.2
acetyl-CoA carboxylase 2 10.0
glycerol-3-phosphate acyltransferase, mitochondrial 10.0
APC2 protein 10.0
malonyl-CoA decarboxylase 9.9
CPT1A 9.9
TSC1 protein 9.8
TIMM44 9.8
NDUFB5 9.8
CALR protein 9.8
MOGAT2 9.8
DHRS7 9.8
VLCAD 9.7
LPGAT1 9.6
Inosine triphosphatase 9.6
acyl-CoA synthetase long-chain family member 1 9.5
long-chain acyl-CoA dehydrogenase 9.5
carnitine palmitoyltransferase 1C 9.5
ATP-binding cassette transporter-1 9.5
CACT 9.5
SLC27A5 9.4
2,4-dienoyl-CoA reductase 9.4
pyruvate dehydrogenase kinase 4 9.4
aspartate aminotransferase 1 9.2
palmitoyl-CoA hydrolase 9.2
cot 9.1
carnitine palmitoyltransferase 1 9.1
BCKDK 9.1
INPP5K 9.1
Delta(3)-Delta(2)-enoyl-CoA isomerase 9.1
MCAD 9.0
NETO1 9.0
DC12 9.0
ACOX1 8.9
very-long-chain acyl-CoA dehydrogenase 8.9
UDP-glucuronosyltransferase 2B7 8.9
acetyl-CoA carboxylase 8.9
mitochondrial 3-oxoacyl-CoA thiolase 8.9
MECR 8.9
Acetyl-CoA hydrolase 8.9
acetyl-CoA carboxylase alpha 8.8
sterol regulatory element-binding protein-1c 8.8
ACOT7 8.8
dehydrodolichyl diphosphate synthase 8.8
collagen, type I, alpha 1 8.8
UGT2B7 protein 8.8
more...
Disease
Carnitine palmitoyltransferase I deficiency 12.8
Carnitine palmitoyltransferase deficiency 12.3
CPT1 deficiency 12.3
Carnitine palmitoyltransferase II deficiency 11.8
Blindness and low vision 11.8
Disorders of mitochondrial metabolism 11.8
Metabolic myopathy 11.2
Drug-induced cardiomyopathy 10.8
Metabolic cardiomyopathy 10.8
Disorders of fatty acid oxidation 10.4
Ketonemia 9.3
Myoadenylate deaminase deficiency 9.0
Metabolic encephalopathy 8.7
OIC 8.4
Reye 7.7
Carnitine deficiency 7.6
metagonimiasis 7.5
CPS deficiency 7.5
SCD 7.1
CPX 7.1
Conduction disorders 6.9
Wolcott-Rallison syndrome 6.9
McArdle's disease 6.9
Lymphatic metastasis 6.8
FAS 6.8
FVR 6.8
lipid disorder 6.6
Tauri 6.5
Acute encephalopathy 6.4
neurobehavioral problems 6.4
PDH deficiency 6.3
schizotypal personality disorder 6.1
Cancer cachexia 6.1
Large cell neuroendocrine carcinoma 6.1
fatty liver 6.0
glutaric aciduria 5.9
diabetic ulcer 5.8
MCD 5.8
Inattention 5.7
ICD 5.7
lipoproteinemia 5.6
FA2 5.6
riboflavin deficiency 5.6
ornithine transcarbamylase deficiency 5.5
postmaturity 5.5
SCP 5.5
MCAD deficiency 5.5
FRA 5.5
enzyme deficiency 5.5
intermittent explosive disorder 5.5
disruptive behavior disorder 5.4
Zellweger syndrome 5.4
alcoholic fatty liver 5.4
hyperargininemia 5.4
recurrent gastric cancer 5.4
Diabetic peripheral neuropathy 5.3
AD2 5.3
VIN 5.3
Forbes 5.3
choroid plexus carcinoma 5.2
child physical abuse 5.2
macromastia 5.2
MELAS 5.2
tympanosclerosis 5.1
Nonalcoholic fatty liver 5.1
avoidant personality disorder 5.1
stage III colon cancer 5.1
PCT 5.1
CDT 5.1
MERRF 5.1
ADHD 5.0
Prinzmetal 5.0
cardiac overload 5.0
moderate obesity 5.0
PSP 5.0
OPA1 5.0
methylmalonic acidemia 4.9
choline deficiency 4.9
diabetic cardiomyopathy 4.9
MELAS 4.9
more...
Symptom
Exercise intolerance 6.9
mental fatigue 6.2
dark urine 5.6
physical exhaustion 5.4
generalized pain 5.1
muscle cramps 4.9
hepatomegaly 4.5
myalgia 4.5
hangover 4.3
Poor sleep 4.2
starvation 3.9
hyperemesis gravidarum 3.7
hypocapnia 3.6
presyncope 3.5
thigh pain 3.4
partial seizure 3.3
chronic back pain 3.2
cachexia 3.1
menopausal symptoms 3.1
neurological disability 2.9
muscle rigidity 2.7
tense 2.7
weakness 2.6
hypotonia 2.6
hot flushes 2.5
tachypnea 2.5
Mills 2.4
hyperoxia 2.4
distraction 2.4
lethargy 2.3
HSA 2.2
anorexia 2.2
ophthalmoplegia 2.1
bloating 2.1
alexithymia 2.0
epigastric pain 2.0
fatigue 1.9
functional recovery 1.9
pelvic pain 1.8
polydipsia 1.7
facial pain 1.6
dysuria 1.5
hypothermia 1.5
paresthesia 1.5
pallor 1.5
numbness 1.4
shortness of breath 1.4
overweight 1.4
hypercapnia 1.4
insomnia 1.4
angina 1.2
polyuria 1.2
diarrhea 1.1
tinnitus 1.1
constipation 1.0
seizures 0.9
spasm 0.9
pain 0.8
nausea 0.8
neck pain 0.8
acute pain 0.8
hepatosplenomegaly 0.7
exhaustion 0.6
acute stress 0.6
syncope 0.6
analgesia 0.6
nausea and vomiting 0.5
low back pain 0.5
hunger 0.3
agitation 0.2
back pain 0.2
hemoptysis 0.2
sleepiness 0.1
dyspnea -0.0
collapse -0.0
arthralgia -0.0
discomfort -0.1
abdominal pain -0.2
vomiting -0.2
Welt -0.2
more...
Drug
Edodekin alfa 11.8
Oxfenicine 11.2
Metastat 10.0
Manidipine hydrochloride 9.6
Cassia seed 9.6
Parecoxib sodium 9.3
Perhexiline 9.2
Alclofenac 9.1
Quinidine sulfate 8.8
Hemolink 8.7
Topamax 7.9
CPT-11 7.7
Doxifluridine 7.5
Cilomilast 7.4
Creosote 7.1
Irinotecan 7.0
Elvitegravir 6.9
Enprostil 6.8
Butaprost 6.8
Clofibrate 6.8
Lumefantrine 6.8
Kaletra 6.7
Bezafibrate 6.6
Ciprofibrate 6.5
Rosiglitazone 6.4
Dronedarone 6.3
Palmitoyl 6.2
Icodextrin 6.0
Liposyn 5.9
Safflower 5.8
Nesiritide 5.8
Rhubarb 5.8
Saha 5.7
PNT 5.7
Ximelagatran 5.6
Rolipram 5.6
Febuxostat 5.6
Apixaban 5.6
Norvir 5.6
Zileuton 5.5
Xeloda 5.5
Rasagiline 5.5
CPZ 5.5
Calcipotriol 5.4
Vardenafil 5.3
Navelbine 5.3
Forskolin 5.2
ATV 5.2
Orlistat 5.2
Abatacept 5.1
linolenate 5.1
Palivizumab 5.1
Atomoxetine 5.1
Rosuvastatin 4.9
Raltegravir 4.9
Pirfenidone 4.9
Loratadine 4.8
OIF 4.8
Compound 9 4.8
Levonorgestrel 4.6
Ketotifen 4.6
CFT 4.6
Sodium nitroprusside 4.4
Colombo 4.4
Ritalin 4.4
DEL 4.4
Glucagon 4.4
AC2 4.4
K-252a 4.3
Adenosine deaminase 4.3
Vorinostat 4.3
TTC 4.2
Trimethoprim-sulfamethoxazole 4.2
Modafinil 4.2
SBT 4.1
Ipilimumab 4.1
ADR 4.1
Bumetanide 4.1
CPR 4.0
Vinorelbine 4.0
more...
Enzyme
CPT 12.8
CPT 12.8
CPT 12.6
glycerophospholipid acyltransferase 11.2
secologanin synthase 10.3
carnitine acetyltransferase 10.2
long-chain acyl-coenzyme A dehydrogenase 10.0
malonyl-CoA decarboxylase 9.8
palmitoyl-CoA hydrolase 9.5
acyl-CoA oxidase 9.5
carnitine O-octanoyltransferase 9.4
2,4-dienoyl-CoA reductase 9.4
trimethyllysine dioxygenase 9.3
rubber transferase 8.9
acetyl-CoA carboxylase 8.8
acyl-CoA dehydrogenase 8.6
EC 5.3.3.8 8.5
HMG-CoA synthase 8.4
glycerophosphate acyltransferase 8.4
acyl-CoA dehydrogenase 8.2
3-hydroxyacyl-CoA dehydrogenase 8.1
PAF acetyltransferase 8.1
gamma-butyrobetaine hydroxylase 8.0
acyl-CoA synthetase 7.8
acyl-CoA synthetase 7.8
3-hydroxyacyl-CoA dehydrogenase 7.7
diacylglycerol acyltransferase 7.6
hormone-sensitive lipase 7.5
fatty-acid synthase 7.5
EC 1.1.1.82 7.4
PAF acetyltransferase 7.4
butyryl-CoA dehydrogenase 7.4
fatty acid elongase 7.3
gluconate dehydrogenase 7.3
phosphotransbutyrylase 7.3
arogenate dehydrogenase 7.2
oxoglutarate dehydrogenase 7.0
sterol carrier protein 6.9
beta-hydroxybutyrate dehydrogenase 6.8
PDK1 6.7
AMP-activated protein kinase 6.7
citrate synthase 6.7
AMPK 6.7
EPT 6.6
3-hydroxy-3-methylglutaryl-CoA lyase 6.5
NADPH:quinone oxidoreductase 6.4
KAT 6.3
AMPK 6.2
PKG 6.2
3-oxoacid CoA-transferase 6.2
lipoprotein lipase 6.1
phosphatidylglycerophosphate synthase 6.1
ketohexokinase 6.1
LPL 6.0
acetoacetyl-CoA thiolase 6.0
pyruvate dehydrogenase 6.0
pyruvate dehydrogenase 6.0
phosphofructokinase 1 5.9
phosphoenolpyruvate carboxykinase 5.9
phosphoenolpyruvate carboxykinase 5.9
adenosine kinase 5.9
ECH 5.9
phosphoenolpyruvate carboxykinase 5.9
3-hydroxy-3-methylglutaryl-CoA reductase 5.8
glucose-6-phosphatase 5.8
acyl-CoA thioesterase 5.7
pyruvate dehydrogenase 5.7
uricase 5.7
iodothyronine 5'-deiodinase 5.6
glycogenin 5.6
SCP 5.5
TMT 5.5
glycine amidinotransferase 5.4
ubiquinol-cytochrome c oxidoreductase 5.4
VIP1 5.4
phosphofructokinase 5.3
SPT 5.3
glucokinase 5.3
SPT 5.3
6-phosphogluconate dehydrogenase 5.3
more...
Compound
CPT 12.8
CPT 12.6
Palmitoyl-L-carnitine 11.0
1-(phenylsulfonyl)-1H-indole 10.8
Avizafone 10.8
Batatasin I 10.4
malonyl-CoA 10.4
TDGA 10.2
8-Cyclopentyltheophylline 10.0
Methyl palmoxirate 9.9
Ginkgolide C 9.8
palmitoyl-CoA 9.7
Octanoylcarnitine 9.6
D-Carnitine 9.6
Coproporphyrin I 9.4
Coproporphyrin I 9.4
Coproporphyrin I 9.4
Coproporphyrin I 9.4
Coproporphyrin I 9.4
Fagaronine 9.4
Thyronine 9.3
Methylmalonyl-CoA 9.2
Carnitine 9.1
PC-4 9.1
octanoyl-CoA 9.0
Sinensetin 9.0
Ginkgolide C 8.9
Buformin 8.6
Quinidine sulfate 8.5
Ammonium perfluorooctanoate 8.4
Coniferaldehyde 8.4
L-carnitine 8.4
hexadecanedioic acid 8.1
gamma-Linolenic acid 8.1
Rocaglamide 8.1
Hoechst dye 33258 8.0
AD 32 7.8
C acid 7.8
CPT-11 7.7
linoleoyl-CoA 7.6
Camptothecin 7.4
icosane 7.4
SN-38 7.4
Laminariaceae 7.4
tetracosanoic acid 7.4
Camptothecin 7.4
Camptothecin 7.4
3-methylbenzamide 7.3
pentanamide 7.3
Fluticasone 7.3
CoA 7.3
cyclopentyl 7.2
L-methylmalonyl-CoA 7.2
2-Chloroadenosine 7.2
2-Chloroadenosine 7.2
Coenzyme A 7.2
2-furoic acid 7.1
Myricitrin 7.1
Tributyrin 7.1
diethyl succinate 7.1
Ethionine 7.0
2-furoic acid 7.0
Tolcapone 7.0
Granulin 7.0
Tolmetin 7.0
DCI 6.9
Fenofibrate 6.8
Pterostilbene 6.8
CITCO 6.7
Clofibrate 6.7
Zinc pyrithione 6.7
Zinc pyrithione 6.7
Zinc pyrithione 6.7
5-aminopentanoic acid 6.7
Cerulenin 6.6
W37 6.6
Oil Red O 6.6
Nedaplatin 6.6
Bilobalide 6.5
BayK8644 6.5
more...