Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:2.3.1.184 (
LasR
)
897
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
The effect of the natural ketones emitted by bacteria (2-nonanone,
2-heptanone
, 2-undecanone) on the functioning of the Quorum Sensing (QS) systems was studied. In this work, three lux-reporter strains containing the components of the
LasI
/
LasR
,
RhlI
/RhlR,
LuxI
LuxR QS systems were used as biosensors for the N-acyl-homoserine lactones. It was shown that at concentrations of ketones that exhibited little or no bactericidal action the ketones could modulate the QS-response by suppressing the expression of the lux-operon reporter to a greater extent than the cell viability of these strains.
...
PMID:[The ability of the natural ketones to interact with bacterial quorum sensing systems]. 2584 35
