Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: EC:2.3.1.177 (BIS)
 957 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Incorporation of [2-14C]glycine was used to estimate serum protein synthesis in four groups of rats. These were the control (group C); 20% body surface burn (group B); 20% burn, seeded with Pseudomonas aeruginosa (group BI); and burned-infected treated topically with mafenide (alpha-amino-p-toluenesulfonamide) acetate (group BIS), a treatment which controls P, aeruginosa burn-wound infection in humans. On the 6th day postburn the relative specific activities of all fractions were increased in the order BI greater than BIS greater than B greater than C, as were the concentrations of the globulins; Serum albumin concentration fell, being lowest in BI. Tissue albumin contents, measured by radioimmunoassay, of eviscerated blood-free bodies of rats were (mg/100 g rat wt): C, 207; B, 294; BI, 256. Analyses of individual tissues showed that the difference was due to increased albumin content in the burn-wound area. The tissue albumin was of normal molecular size and was immunologically reactive. We conclude that the prolonged hypoalbuminemia following burn injury is not a consequence of impaired albumin synthesis, but a result of altered compartmentation.
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PMID:Protein metabolism in burned rats. 96

The water from 20 wells of Nari area was assessed for different quality parameters. The nitrate (NO(-)3) concentration ranged from 57 to 80 ppm which is above the BIS limit while nitrite (NO(-02) concentration was within the BIS limit of 0.02 ppm. The pH of the water samples varied from 7.3 to 8.2. The concentrations of micronutrient cations, namely Zn, Fe, Cu and Mn, were below the toxic level in all the samples but some of the samples of the water had high and infinite growth of E. coli, Coliform bacteria, Pseudomonas aerugilosa, Yeast and molds count makes the well water of poor quality for drinking purpose.
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PMID:Assessment of well-water quality for drinking purpose--a case study in Nari area, Nagpur District, Maharashtra (India). 2474 4