Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: EC:2.3.1.177 (BIS)
 957 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The single application of a BIS-GMA adhesive sealant in Kalispell on a paired half-moouth basis and the annual monitoring of the sealed sites for five years is not a recommended preventive regimen. The study does proved information on the potential long-term in vivo retention of the sealant and its ability to prevent dental caries. The findings of this study clearly show that when this pit and fissure sealant is retained, its is effective in preventing caries in sealed tooth surfaces. Moreover, on occlusal surfaces, the usual susceptibility to decay is not altered by having been treated with a sealant that is not retained.
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PMID:Retention and effectiveness of a single application of an adhesive sealant in preventing occlusal caries: final report after five years of a study in Kalispell, Montana. 27 77

To clarify the high hemolytic activity of BIS-GMA, the molar concentration producing 50% hemolysis (H50) and the partition coefficient inoctanol-water were determined using BIS-GMA and various types of methacrylates. It is suggested that the strong hemolytic potency of BIS-GMA is due to the high hydrophobic nature of the compound.
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PMID:Studies on hemolytic activity of bisphenol A diglycidyl methacrylate (BIS-GMA). 27 7

Various particulate materials were combined with a BIS-GMA resin, and the resulting composites were evaluated. The fillers prevented, altered, had no apparent effect, or accelerated polymerization. Coupling agents also influenced polymerization. Physical properties varied widely with different fillers.
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PMID:Metal-filled resin composites. II. 27 16

For the biological examination of dental resin filling materials, a solubility and hemolysis test is recommended as an in-vitro testing method. Solubility and degree of hemolysis were examined in various filling materials based on MMA and BIS-GMA. It was found that, at the beginning, solubility was considerably higher in MMA-containing materials than in the BIS-GMA systems, and that after a while the conditions were reversed. The degree of hemolysis decreased in the following order with the individual materials: 1. Posite, Sevriton, Adatpic, 2. Epoxylite, Smile, Palakav, 3. MMA-BPO/Amin and MMA-TBBO. Comparison between the MMA and BIS-GMA monomers showed that corresponding to the same molar amounts, BIS-GMA materials developed a higher degree of hemolysis.
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PMID:[Solubility and degree of hemolysis as methods for the in vitro evaluation of dental filling materials]. 28 Apr 52

Temporary splints to immobilize periodontally diseased teeth were made by fiber glass bonded and attached to the teeth with acid-etch technique with BIS-GMA resin. Twenty-one splints were made. Observation time ranged from 4 to 14 months. During the observation only one splint fractured and was repaired while the others functioned without failure.
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PMID:Fiber glass splints. 28 40

Six systems (one polycarboxylate, one polymethyl methacrylate, one unfilled BIS-GMA resin, two combinations of methyl cyanoacrylate and polymethyl methacrylate, and one combination of unfilled BIS-GMA and filled composite resin) were evaluated for in vitro retention to acid-etched human enamel. Also tested were one unfilled-filled resin combination backed by perforated orthodontic band metal and another unfilled resin backed by stainless steel wire mesh. Significant differences in retention were found. Results show that retention depends pril surface and to resist subsequent chemical degradation.
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PMID:Strength determination of periodontal splints fabricated from acid-etched retained materials. 32 49

One hundred and forty-three patients ranging in age from 5 to 8 years participated in a pit and fissure sealant study using a half-mouth design. At the end of 18 months, for all permanent first molars, there was a 75.9% effectiveness with a net gain of 82, which was statistically significant. The sealant was present on the surfaces to which it was applied in 74% of the teeth. Application time was 8 minutes per quadrant and 5.5 minutes per tooth. The effect of treatment was similar to that reported for an unfilled BIS-GMA sealant in patients with similar teeth and similar ages. Loss of sealant from the permanent maxillary first molars did not appear to contribute to the initiation of dental caries. However, in 6 of 38 mandibular tooth surfaces, sealant loss may have been a factor.
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PMID:A filled pit and fissure sealant: 18-month results. 33 Jun 2

A comparison was made of scoring the retention status of BIS-GMA occlusal sealants 5 years after they had been placed, according to a non-blind and blind method of identification of teeth that had been sealed. Subjects were 175 children ages 15--18. One examiner made all the assessments. Retention of sealant was classified as all present, partly missing or all missing. There was 90.5% complete agreement between non-blind and blind examinations in scoring the retention status of 893 occlusal sites. Essentially no difference in agreement was found between sites on maxillary and mandibular teeth nor according to sites in specific teeth. There was only a slight tendency to classify more sites as having sealant present at the non-blind examinations than at the blind examinations, 56.7% and 55.1%, respectively. These findings would seem to indicate that whether examinations are done blindly or non-blindly is of minor importance in making an accurate assessment of sealant retention.
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PMID:Comparison of blind and non-blind assessments of occlusal sealant retention. 34 82

The frequency of complete penetration of two commercial BIS-GMA resin pit and fissure coating materials into wide and constricted fissures was assessed from photomicrographs. It was found that 334 of the 390 wide fissures examined were completely filled by the coating materials. However, in contrast, only 28 of the 650 constricted fissures examined were completely filled by these resins.
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PMID:An in vitro investigation of the penetrating efficacy of BIS-GMA resin pit and fissure coatings. 35 14

A single application of a filled chemically initiated BIS-GMA sealant to permanent first molars of children ranging in age from 5 to 8 years covered the original sites in 52.4% of the 185 teeth examined after four years. Retention of sealant is greater in mandibular (64.7%) than in maxillary (42.0%) molars. The rate of loss of sealant was greatest during the first year (20%), then less than 10% per year at the second, third, and fourth recalls. In comparison with two similar studies, the retention of sealant was 20% to 30% greater. Using the parameters of percent effectiveness, net gain, and DMF scores per 100 test and control teeth, the data from the current study indicate a continued positive effect substantially greater than that in other similar studies. Complete loss of sealant does not appear to predispose that surface to caries any more than its contralateral paired surface. However, a partial loss of sealant because of abrasive wear that results in the exposure of the terminal ends of a fissure is a potential failure in that it creates an environment conducive to caries. Thus, even the well-applied sealant does not necessarily constitute permanent obturation of pits and fissures. Periodic clinical observation is necessary to determine the success or potential failure of the sealant treatment.
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PMID:Clinical success and potential failure after single application of a pit and fissure sealant: a four-year report. 37 86


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