Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: EC:2.3.1.177 (BIS)
 957 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Over the past twenty years, oncology has taken into account the study of patient's quality of life. This article offers a review of the quality of life questionnaires that are currently being used in cancerology: QLQC-30 and its modules, FLIC, FACT-G and its modules, BIS, SF-36. Among these evaluation tools, two questionnaires which have been validated in French can be used to evaluate the quality of life of women suffering from breast cancer: QLQBR-23 and FACT-B. However, these two questionnaires target the quality of life of women suffering from breast cancer in general without taking into account the specific characteristics of these women and their past experiences; such as their age or their family's situation. It seems important to study which topics could be specific to young women at the time of diagnosis (education or desire for a child [ren], couple relationship, professional life), all of which are important issues for women in this situation. Besides, there appears to be no questionnaire which specifically evaluates the partner's quality of life, even though he is frequently the first source of support for these women. Directions for future research will be suggested based on the necessity of having specific measures of the quality of life of the young woman suffering from breast cancer and her partner. Such a tool could be useful in a clinical setting within the context of the care of these young women with particular profiles.
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PMID:[Assessing the quality of life of young women and their partners: a pertinent approach to the study of breast cancer]. 1943 88

Objective: To report the trends in quality of life (QoL) reporting for radical cystectomy (RC) and urinary diversion (UD) over the last four decades, as RC for bladder cancer is associated with significant morbidity and QoL issues. Material and methods: We searched PubMed, Medical Literature Analysis and Retrieval System Online (MEDLINE), Excerpta Medica dataBASE (EMBASE), Cumulative Index to Nursing and Allied Health Literature (CINAHL), and the Cochrane library for published studies from January 1980 to January 2017 in the English language. We divided the published articles into three time periods: period-1 (1980-1997), period-2 (1998-2007) and period-3 (2008-2017). Results: A total of 85 QoL studies (8417 patients) were identified, of which 3347 (39.8%) patients had an ileal conduit (IC), 1078 (12.8%) had a continent UD (CD), 3264 (38.8%) had a neobladder (NB), and in the remaining 728 (8.6%) the type of UD was not specified. Whilst there were 15, 24 and 41 studies in period-1, period-2 and period-3 respectively, two (13%), 20 (83%) and 37 (90%) used a validated QoL tool; and none, six (25%) and 23 (56%) used a urology specific QoL tool during these three time periods. Similarly, the number of prospective studies increased from one (7%) to four (17%) and 14 (34%) in these three time periods. The proportion of reported IC patients reduced from 65% (784 patients) to 36% (899) and 35% (1664) from period-1 to period-3, whereas the proportion of NB patients increased from 4.5% (54) to 44% (1105) and 44% (2105). Over the last few years there have been QoL studies on laparoscopic and robotic IC and NB UDs. Conclusion: Our review suggests an increasing use of validated, bladder cancer-specific questionnaires with UD-specific constructs. Abbreviations: BCI: Bladder Cancer Index; BDI: Beck Depression Inventory; BIS: Body Image Scale; CD: continent urinary diversion; EORTC QLQ-30C: European Organisation for the Research and Treatment of Cancer Quality of Life 30-item core questionnaire; ERAS: enhanced recovery after surgery; FACT(-BL)(-G)(-VCI): Functional Assessment of Cancer Therapy(-Bladder Cancer)(-General)(-Vanderbilt Cystectomy Index); IC: ileal conduit; NB: neobladder; (HR)QoL: (health-related) quality of life; (RA)RC: (robot-assisted) radical cystectomy; SF-36: 36-item short-form health survey; SIP: Sickness Impact Profile; UD: urinary diversion.
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PMID:Trends in quality of life reporting for radical cystectomy and urinary diversion over the last four decades: A systematic review of the literature. 3148 33