Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: EC:2.3.1.177 (BIS)
957 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

For the biological examination of dental resin filling materials, a solubility and hemolysis test is recommended as an in-vitro testing method. Solubility and degree of hemolysis were examined in various filling materials based on MMA and BIS-GMA. It was found that, at the beginning, solubility was considerably higher in MMA-containing materials than in the BIS-GMA systems, and that after a while the conditions were reversed. The degree of hemolysis decreased in the following order with the individual materials: 1. Posite, Sevriton, Adatpic, 2. Epoxylite, Smile, Palakav, 3. MMA-BPO/Amin and MMA-TBBO. Comparison between the MMA and BIS-GMA monomers showed that corresponding to the same molar amounts, BIS-GMA materials developed a higher degree of hemolysis.
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PMID:[Solubility and degree of hemolysis as methods for the in vitro evaluation of dental filling materials]. 28 Apr 52

A study on the composition of the resin component of the several brands of composite resin has not been published so far. It was the purpose of the present work to fill out this gap in our knowledge of this important group of restorative materials by analyzing the monomers of the materials as delivered by the manufacturers. 24 brands of restorative resins were investigated by means of a Nuclear Magnetic Resonance spectrometer at 90 MHz. Spectra were taken of deuterated chloroform solutions of the organic part of the filling materials and compared with spectra of pure monomers that were conceivable constituents of the investigated brands. It was found that the BIS-GMA containing brands all contain at least one other monomer, most often TEDMA, in varying concentrations. The brands with MMA as main component in most cases also contain other monomers.
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PMID:NMR-analysis of monomers in restorative resins. 106 16

Methyl methacrylate-based (MMA-based) bonding resins have been used in orthodontics because they offer easy removal of both the bonded bracket and the residual adhesive at case completion. However, these materials are not cross-linked, and the brackets bonded with this type of product may undergo drifting when subjected to temperatures slightly higher than those in the mouth. This research investigated the influence of heat on the debonding characteristics of a MMA-based bonding resin compared with those of a BIS-GMA-based system. The temperature of initial bracket movement, as well as of final bracket displacement, was noted for a variety of applied loads (141, 226, 425, 934, and 1727 gm) with stainless steel brackets bonded to etched bovine enamel. The results showed that the MMA-based material underwent a glass transition near 47 degrees C in which the initiation of bracket drift resulted on the tooth surface. This temperature proved independent of the applied load. Further heating resulted in the release of heat from the resin as a result of further curing. The extent of bracket drift associated with this secondary heat release was dependent on the applied load. The debonding temperature of the BIS-GMA-based system was three to six times greater than that of the MMA-based product. Practitioners should be aware that brackets bonded with MMA-based resins have the potential for drifting when subjected to temperatures within the normal range of hot fluids consumed by their patients. Bracket drift could result in deactivation of orthodontic force and could prolong the treatment time.
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PMID:Thermal properties of a methyl methacrylate-based orthodontic bonding adhesive. 153 85