Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:2.3.1.177 (BIS)
 957 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A 106-year-old female underwent emergency colectomy for peritonitis secondary to ischemic colitis. Following induction of anaesthesia with 18 mg etomidate (0,4 mg/kg), BIS monitoring allowed to perform surgery with an averaged desflurane end-tidal concentration and remifentanil infusion as low as 0.9% and 0.057 microg/kg/minute respectively. The mean BIS value was of 45+/-4 (min = 38, max = 50), systolic arterial pressure was maintained within+/-10% of control values during 72% of anaesthesia duration (160 min) and the maximal drop did not exceed 27%. No adrenergic agent was used. This observation underlined the interest of BIS when anaesthetic requirement are difficult to estimate rapidly.
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PMID:[Which doses of anaesthetic agents in centenarian patients? Interest of BIS monitoring]. 1592 47