Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:2.3.1.109 (AST)
6,066 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
AST 6039
ALP 845
LDH 712
GSH 622
aspartate aminotransferase 543
SOD 476
TNF 476
albumin 462
GGT 403
alkaline phosphatase 377
Sep 368
alanine aminotransferase 346
IL-6 298
superoxide dismutase 287
catalase 278
CAT 271
HDL 260
insulin 232
glutathione peroxidase 174
lactate dehydrogenase 173
caspase-3 172
Mol 167
hemoglobin 159
cytokine 132
collagen 118
prothrombin 117
tumor necrosis factor 114
IFN 114
lipopolysaccharide 113
Bcl-2 111
ROS 100
GST 98
inducible nitric oxide synthase 97
IL-10 96
creatine kinase 92
Nrf2 89
galactosamine 85
myeloperoxidase 84
CRP 79
interferon 78
CPK 75
HO-1 74
LPS 74
CYP2E1 74
serum albumin 68
amylase 67
SMA 64
gut 64
ATP 62
p53 61
COX-2 60
ALB 55
antioxidant enzyme 53
fibrinogen 52
ferritin 48
TLR4 48
JNK 47
glutathione reductase 46
PPAR 46
p65 45
endoplasmic reticulum 44
lipase 44
MAPK 44
FIB 44
p38 43
C-reactive protein 42
IL-2 42
cytochrome P450 42
IL-4 42
glutathione S-transferase 40
TNF-alpha 39
AFP 39
transferrin 39
gamma-glutamyltransferase 39
She 39
CD4 38
interleukin-6 38
GPT 38
MCP-1 37
LPO 37
more...
Disease
GSH 622
cirrhosis 294
hepatitis 294
liver disease 279
chronic hepatitis 235
cancer 234
fatty liver 224
diabetes 221
liver fibrosis 207
ischemia 204
hepatocellular carcinoma 196
hepatitis C 189
tumor 187
hepatitis B 168
obesity 137
cold 98
alcoholic fatty liver 95
thrombocytopenia 93
cholestasis 89
anemia 83
HIV 79
viral hepatitis 76
chronic liver disease 74
hypertension 74
metabolic syndrome 73
hyperlipidemia 73
type 2 diabetes 73
sepsis 69
acute hepatitis 68
sepsis 66
Nonalcoholic fatty liver 65
depression 59
liver cancer 57
hyperglycemia 50
cardiovascular disease 50
virus infection 47
myocardial infarction 45
dyslipidemia 45
breast cancer 45
alcoholism 43
chronic renal failure 42
alcohol abuse 41
renal disease 41
renal failure 41
neutropenia 38
infectious diseases 38
carcinoma 37
leukopenia 37
Hepatotoxicity 37
rash 37
chronic active hepatitis 36
tuberculosis 35
carcinogenesis 35
proteinuria 34
atherosclerosis 34
primary biliary cirrhosis 34
viremia 33
pruritus 32
ACP 32
dengue 32
hepatitis A 31
hypercholesterolemia 29
liver cancer 29
encephalopathy 28
hepatic encephalopathy 28
hyperbilirubinemia 27
lymphoma 27
alcoholic hepatitis 27
HCC 26
rheumatoid arthritis 25
myocardial ischemia 25
acute pancreatitis 24
AIDS 24
hypoglycemia 24
arthritis 23
pneumonia 23
iron overload 22
schistosomiasis 22
tumor growth 22
coagulopathy 21
more...
Symptom
diarrhea 87
hepatomegaly 65
fatigue 64
nausea 56
pain 55
abdominal pain 54
vomiting 53
anesthesia 40
splenomegaly 37
anorexia 36
weakness 30
headache 26
overweight 24
myalgia 23
cough 18
Ill 17
dyspnea 15
erythema 14
hypothermia 14
nausea and vomiting 14
seizures 13
lethargy 12
hepatosplenomegaly 12
arthralgia 11
epigastric pain 10
tremor 9
exhaustion 8
oliguria 8
starvation 8
asthenia 8
respiratory distress 7
flushing 7
discomfort 7
angina 7
constipation 7
discomfort 7
hypoproteinemia 6
ataxia 6
decreased appetite 6
cyanosis 6
agitation 5
analgesia 5
collapse 5
nasal discharge 5
regurgitation 5
incoordination 5
colic 5
chills 5
functional recovery 4
fever of unknown origin 4
paresis 4
polyuria 4
acute stress 4
polydipsia 4
chest pain 3
apathy 3
shortness of breath 3
lassitude 3
hypotonia 3
ketonuria 3
acidity 3
sore throat 3
consciousness disturbance 3
back pain 3
sleepiness 3
dizziness 3
abdominal discomfort 3
abdominal cramps 3
hypercapnia 2
frequent urination 2
No adverse effect 2
pallor 2
bone pain 2
blurred vision 2
right upper quadrant pain 2
tachypnea 2
dystonia 2
hyperoxia 2
dysarthria 2
rhinorrhea 2
more...
Drug
ROS 100
ascorbate 45
vitamin E 43
IL-2 42
Ethanol 23
ROC 21
Monit 20
TAC 19
CTX 18
Alanine 17
Albumin 17
IFN-gamma 16
Dial 14
Nephron 13
CSF 13
MAP 13
Vitamin E 13
Nephron 11
Glutathione 11
CCL 10
Heme 10
ALA 10
Bifidobacterium 10
Dermatol 10
lysine 10
CTX 9
CTX 9
Cardiovasc 9
caffeine 9
Portal 8
Fructose 8
NAG 7
ampicillin 7
Serum albumin 7
lactose 6
Leaf 6
NH3 6
Aloe 6
Tacrolimus 6
ZnO 5
Rosiglitazone 5
Acacia 5
Vitamin B 5
Rutin 5
Asn 5
Simvastatin 5
Glycyrrhiza 5
TiO2 4
TTC 4
ENT 4
pyridoxal phosphate 4
Sorafenib 4
NADH 4
Ginseng 4
Biopolymers 4
Liraglutide 4
Ringer's solution 4
Captopril 4
Senna 3
EE2 3
G-CSF 3
EPA 3
Caspofungin 3
RFP 3
Emodin 3
OTC 3
niacin 3
Emodin 3
Isotretinoin 3
Rosuvastatin 3
Fluorescein 3
Prednisone 3
Gel 3
PMEA 3
MRC 3
MOF 3
TMS 3
Senna 3
DNase I 3
Isoniazid 3
more...
Enzyme
AST 6066
aspartate aminotransferase 6039
alanine aminotransferase 4535
superoxide dismutase 728
catalase 528
gamma-glutamyl transpeptidase 527
alkaline phosphatase 378
lactate dehydrogenase 190
glutathione peroxidase 176
creatine kinase 171
glutathione S-transferase 135
caspase-3 119
mitogen-activated protein kinase 103
peroxidase 102
ERK 66
acetylcholinesterase 48
AMP-activated protein kinase 48
lipase 45
glutathione reductase 43
cholinesterase 42
AMPK 37
AMPK 37
NQO1 31
ATPase 28
focal adhesion kinase 28
glucose-6-phosphate dehydrogenase 22
caspase-9 22
glutamate dehydrogenase 21
glutamate dehydrogenase 21
glutamate dehydrogenase 21
lysozyme 20
protein kinase 19
CYP3A4 19
malate dehydrogenase 18
PARP 17
MIP 16
luciferase 16
reverse transcriptase 15
MDH 15
MDH 15
thromboplastin 15
alcohol dehydrogenase 15
caspase-1 14
CPT 14
GMT 14
collagenase 14
acid phosphatase 13
NOS 13
xanthine oxidase 12
ACE 12
glucose-6-phosphatase 10
phosphoenolpyruvate carboxykinase 10
MMP 10
ceruloplasmin 10
PST 10
acetyl-CoA carboxylase 10
LPL 10
arginase 9
aldehyde dehydrogenase 9
CYP7A1 9
gamma-glutamylcysteine synthetase 9
aryl sulfotransferase IV 9
MAP 9
GSK 9
renin 8
CPT 8
NADPH oxidase 8
CPT 8
heme oxygenase 8
hexokinase 8
caspase-8 8
ECH 7
NADPH oxidase 7
estrogen sulfotransferase 7
transpeptidase 7
aldolase 7
NO synthase 7
SOAT 7
glutamine synthetase 7
thymidine kinase 7
more...
Compound
ALP 845
creatinine 687
GSH 631
GSH 631
glucose 601
urea 526
TNF 476
MDA 439
Clin 425
Dec 418
water 357
DNA 281
CAT 278
CAT 271
CAT 271
ethanol 236
oxygen 222
alanine 214
sodium 175
CCl4 166
calcium 148
nitrogen 131
iron 115
APAP 107
nitric oxide 107
potassium 106
sulfate 82
phosphate 68
ammonia 66
zinc 64
ATP 62
methionine 60
copper 59
phosphorus 56
acetate 53
arginine 52
methanol 51
cadmium 46
galactose 46
selenium 46
His 41
cysteine 40
MTT 39
GPT 38
N-acetylcysteine 38
DPPH 37
ethyl acetate 35
GSSG 34
glutamate 32
MCH 31
Asp 31
GTP 30
hyaluronic acid 30
nitrate 29
hydrogen 28
leucine 28
Bilirubin 28
salt 26
tyrosine 25
gallic acid 25
alloxan 25
STZ 24
Indoxyl sulfate 24
TSH 24
NH2 23
PEG 23
H2O2 23
TOF 22
silver 22
tryptophan 21
aspartic acid 21
tryptophan 21
Silymarin 21
Curcumin 20
tryptophan 20
tryptophan 20
Phe 20
8-OHdG 20
hexane 20
Malondialdehyde 20
more...