Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:2.3.1.109 (
AST
)
6,066
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
AST
6039
ALP
845
LDH
712
GSH
622
aspartate aminotransferase
543
SOD
476
TNF
476
albumin
462
GGT
403
alkaline phosphatase
377
Sep
368
alanine aminotransferase
346
IL-6
298
superoxide dismutase
287
catalase
278
CAT
271
HDL
260
insulin
232
glutathione peroxidase
174
lactate dehydrogenase
173
caspase-3
172
Mol
167
hemoglobin
159
cytokine
132
collagen
118
prothrombin
117
tumor necrosis factor
114
IFN
114
lipopolysaccharide
113
Bcl-2
111
ROS
100
GST
98
inducible nitric oxide synthase
97
IL-10
96
creatine kinase
92
Nrf2
89
galactosamine
85
myeloperoxidase
84
CRP
79
interferon
78
CPK
75
HO-1
74
LPS
74
CYP2E1
74
serum albumin
68
amylase
67
SMA
64
gut
64
ATP
62
p53
61
COX-2
60
ALB
55
antioxidant enzyme
53
fibrinogen
52
ferritin
48
TLR4
48
JNK
47
glutathione reductase
46
PPAR
46
p65
45
endoplasmic reticulum
44
lipase
44
MAPK
44
FIB
44
p38
43
C-reactive protein
42
IL-2
42
cytochrome P450
42
IL-4
42
glutathione S-transferase
40
TNF-alpha
39
AFP
39
transferrin
39
gamma-glutamyltransferase
39
She
39
CD4
38
interleukin-6
38
GPT
38
MCP-1
37
LPO
37
more...
Disease
GSH
622
cirrhosis
294
hepatitis
294
liver disease
279
chronic hepatitis
235
cancer
234
fatty liver
224
diabetes
221
liver fibrosis
207
ischemia
204
hepatocellular carcinoma
196
hepatitis C
189
tumor
187
hepatitis B
168
obesity
137
cold
98
alcoholic fatty liver
95
thrombocytopenia
93
cholestasis
89
anemia
83
HIV
79
viral hepatitis
76
chronic liver disease
74
hypertension
74
metabolic syndrome
73
hyperlipidemia
73
type 2 diabetes
73
sepsis
69
acute hepatitis
68
sepsis
66
Nonalcoholic fatty liver
65
depression
59
liver cancer
57
hyperglycemia
50
cardiovascular disease
50
virus infection
47
myocardial infarction
45
dyslipidemia
45
breast cancer
45
alcoholism
43
chronic renal failure
42
alcohol abuse
41
renal disease
41
renal failure
41
neutropenia
38
infectious diseases
38
carcinoma
37
leukopenia
37
Hepatotoxicity
37
rash
37
chronic active hepatitis
36
tuberculosis
35
carcinogenesis
35
proteinuria
34
atherosclerosis
34
primary biliary cirrhosis
34
viremia
33
pruritus
32
ACP
32
dengue
32
hepatitis A
31
hypercholesterolemia
29
liver cancer
29
encephalopathy
28
hepatic encephalopathy
28
hyperbilirubinemia
27
lymphoma
27
alcoholic hepatitis
27
HCC
26
rheumatoid arthritis
25
myocardial ischemia
25
acute pancreatitis
24
AIDS
24
hypoglycemia
24
arthritis
23
pneumonia
23
iron overload
22
schistosomiasis
22
tumor growth
22
coagulopathy
21
more...
Symptom
diarrhea
87
hepatomegaly
65
fatigue
64
nausea
56
pain
55
abdominal pain
54
vomiting
53
anesthesia
40
splenomegaly
37
anorexia
36
weakness
30
headache
26
overweight
24
myalgia
23
cough
18
Ill
17
dyspnea
15
erythema
14
hypothermia
14
nausea and vomiting
14
seizures
13
lethargy
12
hepatosplenomegaly
12
arthralgia
11
epigastric pain
10
tremor
9
exhaustion
8
oliguria
8
starvation
8
asthenia
8
respiratory distress
7
flushing
7
discomfort
7
angina
7
constipation
7
discomfort
7
hypoproteinemia
6
ataxia
6
decreased appetite
6
cyanosis
6
agitation
5
analgesia
5
collapse
5
nasal discharge
5
regurgitation
5
incoordination
5
colic
5
chills
5
functional recovery
4
fever of unknown origin
4
paresis
4
polyuria
4
acute stress
4
polydipsia
4
chest pain
3
apathy
3
shortness of breath
3
lassitude
3
hypotonia
3
ketonuria
3
acidity
3
sore throat
3
consciousness disturbance
3
back pain
3
sleepiness
3
dizziness
3
abdominal discomfort
3
abdominal cramps
3
hypercapnia
2
frequent urination
2
No adverse effect
2
pallor
2
bone pain
2
blurred vision
2
right upper quadrant pain
2
tachypnea
2
dystonia
2
hyperoxia
2
dysarthria
2
rhinorrhea
2
more...
Drug
ROS
100
ascorbate
45
vitamin E
43
IL-2
42
Ethanol
23
ROC
21
Monit
20
TAC
19
CTX
18
Alanine
17
Albumin
17
IFN-gamma
16
Dial
14
Nephron
13
CSF
13
MAP
13
Vitamin E
13
Nephron
11
Glutathione
11
CCL
10
Heme
10
ALA
10
Bifidobacterium
10
Dermatol
10
lysine
10
CTX
9
CTX
9
Cardiovasc
9
caffeine
9
Portal
8
Fructose
8
NAG
7
ampicillin
7
Serum albumin
7
lactose
6
Leaf
6
NH3
6
Aloe
6
Tacrolimus
6
ZnO
5
Rosiglitazone
5
Acacia
5
Vitamin B
5
Rutin
5
Asn
5
Simvastatin
5
Glycyrrhiza
5
TiO2
4
TTC
4
ENT
4
pyridoxal phosphate
4
Sorafenib
4
NADH
4
Ginseng
4
Biopolymers
4
Liraglutide
4
Ringer's solution
4
Captopril
4
Senna
3
EE2
3
G-CSF
3
EPA
3
Caspofungin
3
RFP
3
Emodin
3
OTC
3
niacin
3
Emodin
3
Isotretinoin
3
Rosuvastatin
3
Fluorescein
3
Prednisone
3
Gel
3
PMEA
3
MRC
3
MOF
3
TMS
3
Senna
3
DNase I
3
Isoniazid
3
more...
Enzyme
AST
6066
aspartate aminotransferase
6039
alanine aminotransferase
4535
superoxide dismutase
728
catalase
528
gamma-glutamyl transpeptidase
527
alkaline phosphatase
378
lactate dehydrogenase
190
glutathione peroxidase
176
creatine kinase
171
glutathione S-transferase
135
caspase-3
119
mitogen-activated protein kinase
103
peroxidase
102
ERK
66
acetylcholinesterase
48
AMP-activated protein kinase
48
lipase
45
glutathione reductase
43
cholinesterase
42
AMPK
37
AMPK
37
NQO1
31
ATPase
28
focal adhesion kinase
28
glucose-6-phosphate dehydrogenase
22
caspase-9
22
glutamate dehydrogenase
21
glutamate dehydrogenase
21
glutamate dehydrogenase
21
lysozyme
20
protein kinase
19
CYP3A4
19
malate dehydrogenase
18
PARP
17
MIP
16
luciferase
16
reverse transcriptase
15
MDH
15
MDH
15
thromboplastin
15
alcohol dehydrogenase
15
caspase-1
14
CPT
14
GMT
14
collagenase
14
acid phosphatase
13
NOS
13
xanthine oxidase
12
ACE
12
glucose-6-phosphatase
10
phosphoenolpyruvate carboxykinase
10
MMP
10
ceruloplasmin
10
PST
10
acetyl-CoA carboxylase
10
LPL
10
arginase
9
aldehyde dehydrogenase
9
CYP7A1
9
gamma-glutamylcysteine synthetase
9
aryl sulfotransferase IV
9
MAP
9
GSK
9
renin
8
CPT
8
NADPH oxidase
8
CPT
8
heme oxygenase
8
hexokinase
8
caspase-8
8
ECH
7
NADPH oxidase
7
estrogen sulfotransferase
7
transpeptidase
7
aldolase
7
NO synthase
7
SOAT
7
glutamine synthetase
7
thymidine kinase
7
more...
Compound
ALP
845
creatinine
687
GSH
631
GSH
631
glucose
601
urea
526
TNF
476
MDA
439
Clin
425
Dec
418
water
357
DNA
281
CAT
278
CAT
271
CAT
271
ethanol
236
oxygen
222
alanine
214
sodium
175
CCl4
166
calcium
148
nitrogen
131
iron
115
APAP
107
nitric oxide
107
potassium
106
sulfate
82
phosphate
68
ammonia
66
zinc
64
ATP
62
methionine
60
copper
59
phosphorus
56
acetate
53
arginine
52
methanol
51
cadmium
46
galactose
46
selenium
46
His
41
cysteine
40
MTT
39
GPT
38
N-acetylcysteine
38
DPPH
37
ethyl acetate
35
GSSG
34
glutamate
32
MCH
31
Asp
31
GTP
30
hyaluronic acid
30
nitrate
29
hydrogen
28
leucine
28
Bilirubin
28
salt
26
tyrosine
25
gallic acid
25
alloxan
25
STZ
24
Indoxyl sulfate
24
TSH
24
NH2
23
PEG
23
H2O2
23
TOF
22
silver
22
tryptophan
21
aspartic acid
21
tryptophan
21
Silymarin
21
Curcumin
20
tryptophan
20
tryptophan
20
Phe
20
8-OHdG
20
hexane
20
Malondialdehyde
20
more...