Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:2.3.1.109 (AST)
 6,066 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
AST 6039
ALP 845
LDH 712
GSH 622
aspartate aminotransferase 543
SOD 476
TNF 476
albumin 462
GGT 403
alkaline phosphatase 377
Sep 368
alanine aminotransferase 346
IL-6 298
superoxide dismutase 287
catalase 278
CAT 271
HDL 260
insulin 232
glutathione peroxidase 174
lactate dehydrogenase 173
caspase-3 172
Mol 167
hemoglobin 159
cytokine 132
collagen 118
prothrombin 117
tumor necrosis factor 114
IFN 114
lipopolysaccharide 113
Bcl-2 111
ROS 100
GST 98
inducible nitric oxide synthase 97
IL-10 96
creatine kinase 92
Nrf2 89
galactosamine 85
myeloperoxidase 84
CRP 79
interferon 78
CPK 75
CYP2E1 74
HO-1 74
LPS 74
serum albumin 68
amylase 67
SMA 64
gut 64
ATP 62
p53 61
COX-2 60
ALB 55
antioxidant enzyme 53
fibrinogen 52
TLR4 48
ferritin 48
JNK 47
PPAR 46
glutathione reductase 46
p65 45
endoplasmic reticulum 44
MAPK 44
FIB 44
lipase 44
p38 43
IL-2 42
C-reactive protein 42
IL-4 42
cytochrome P450 42
glutathione S-transferase 40
She 39
TNF-alpha 39
transferrin 39
AFP 39
gamma-glutamyltransferase 39
GPT 38
interleukin-6 38
CD4 38
AMPK 37
MCP-1 37
LPO 37
serum protein 36
proliferating cell nuclear antigen 35
heme oxygenase-1 35
Gen 34
Pol 34
adiponectin 34
caspase-9 34
chronic renal failure 34
ACP 32
leptin 32
melanin-concentrating hormone 31
erythroid 30
PLT 30
ERK 29
GTP 29
PI3K 29
NMR 29
IL-1 28
ATPase 27
VEGF 27
mTOR 27
NLRP3 26
surface antigen 26
HCC 26
EPA 26
MRI 26
ERK1 25
myoglobin 25
IL-8 25
cytochrome 24
IgA 24
CD8 24
Pseudomonas 24
microsomal 24
NQO1 23
alpha-fetoprotein 23
TOF 22
HSP70 22
STAT3 22
Fas 22
ANOVA 22
glutamate dehydrogenase 21
lysozyme 20
smooth muscle actin 20
FAS 20
AKT 20
CYP3A4 19
ESR 19
ICAM-1 19
IL-17 19
MIC 18
CYP 18
peroxidase 18
TEM 18
GTG 18
STZ 18
SIRT1 18
gamma-glutamyl transpeptidase 17
nitric oxide synthase 17
Aspartate aminotransferase 17
reductase 17
GCLC 17
carp 17
Catalase 17
MMP-9 17
phosphatase 17
glycoprotein 17
LC3 17
GRP78 17
Alkaline phosphatase 17
kit 17
Gal 17
thymus 17
Albumin 17
interferon-alpha 17
cytochrome c 17
Superoxide dismutase 16
acetylcholinesterase 16
PARP 16
more...
Disease
GSH 622
hepatitis 294
cirrhosis 294
liver disease 279
chronic hepatitis 235
cancer 234
fatty liver 224
diabetes 221
liver fibrosis 207
ischemia 204
hepatocellular carcinoma 196
hepatitis C 189
tumor 187
hepatitis B 168
obesity 137
cold 98
alcoholic fatty liver 95
thrombocytopenia 93
cholestasis 89
anemia 83
HIV 79
viral hepatitis 76
hypertension 74
chronic liver disease 74
hyperlipidemia 73
type 2 diabetes 73
metabolic syndrome 73
sepsis 69
acute hepatitis 68
sepsis 66
Nonalcoholic fatty liver 65
depression 59
liver cancer 57
cardiovascular disease 50
hyperglycemia 50
virus infection 47
myocardial infarction 45
dyslipidemia 45
breast cancer 45
alcoholism 43
chronic renal failure 42
alcohol abuse 41
renal failure 41
renal disease 41
infectious diseases 38
neutropenia 38
rash 37
Hepatotoxicity 37
carcinoma 37
leukopenia 37
chronic active hepatitis 36
carcinogenesis 35
tuberculosis 35
primary biliary cirrhosis 34
proteinuria 34
atherosclerosis 34
viremia 33
pruritus 32
dengue 32
ACP 32
hepatitis A 31
hypercholesterolemia 29
liver cancer 29
encephalopathy 28
hepatic encephalopathy 28
lymphoma 27
alcoholic hepatitis 27
hyperbilirubinemia 27
HCC 26
rheumatoid arthritis 25
myocardial ischemia 25
acute pancreatitis 24
hypoglycemia 24
AIDS 24
arthritis 23
pneumonia 23
tumor growth 22
iron overload 22
schistosomiasis 22
gallstones 21
coagulopathy 21
immunodeficiency 20
myopathy 20
dehydration 20
FAS 20
glomerulosclerosis 20
Infection 20
TEM 19
malaria 19
alcoholic cirrhosis 19
acute renal failure 18
portal hypertension 18
TEM 18
cytomegalovirus 17
heart failure 17
pancreatitis 17
eosinophilia 17
metastases 17
cholangitis 17
malnutrition 17
systemic lupus erythematosus 16
primary sclerosing cholangitis 16
sickle cell disease 16
adenocarcinoma 16
glucose intolerance 16
MIP 16
influenza 16
coma 16
West 15
preeclampsia 15
Hepatocellular carcinoma 15
Cirrhosis 15
acute myocardial infarction 15
lymphopenia 15
hypothyroidism 14
plaque 14
lymphadenopathy 14
SEM 14
stroke 14
asthma 14
cardiomyopathy 14
Schistosoma mansoni 13
uterus 13
lung cancer 13
SDS 13
Wilson's disease 12
hyperthyroidism 12
hemorrhagic fever 12
Epstein 12
uremia 12
Acute liver failure 12
thalassemia 12
prostate cancer 12
colon cancer 11
hepatitis E 11
Autoimmune hepatitis 11
osteoporosis 11
peritonitis 11
worms 11
Klebsiella 11
chronic persistent hepatitis 11
fascioliasis 11
Hodgkin's disease 11
disseminated intravascular coagulation 11
leptospirosis 11
polycystic ovary syndrome 10
Evans 10
NAME 10
ulcerative colitis 10
diabetic nephropathy 10
haemophilia 10
CCL 10
fits 10
LAP 10
esophageal varices 10
Still 10
hyperinsulinemia 10
Graves' disease 10
SARS 10
liver metastases 10
more...
Symptom
diarrhea 87
hepatomegaly 65
fatigue 64
nausea 56
pain 55
abdominal pain 54
vomiting 53
anesthesia 40
splenomegaly 37
anorexia 36
weakness 30
headache 26
overweight 24
myalgia 23
cough 18
Ill 17
dyspnea 15
erythema 14
hypothermia 14
nausea and vomiting 14
seizures 13
hepatosplenomegaly 12
lethargy 12
arthralgia 11
epigastric pain 10
tremor 9
starvation 8
asthenia 8
oliguria 8
exhaustion 8
respiratory distress 7
flushing 7
constipation 7
angina 7
discomfort 7
discomfort 7
ataxia 6
cyanosis 6
hypoproteinemia 6
decreased appetite 6
colic 5
nasal discharge 5
collapse 5
agitation 5
analgesia 5
incoordination 5
regurgitation 5
chills 5
acute stress 4
paresis 4
polyuria 4
fever of unknown origin 4
polydipsia 4
functional recovery 4
chest pain 3
shortness of breath 3
lassitude 3
dizziness 3
sleepiness 3
hypotonia 3
acidity 3
sore throat 3
back pain 3
consciousness disturbance 3
abdominal discomfort 3
apathy 3
ketonuria 3
abdominal cramps 3
bone pain 2
skin irritation 2
No adverse effect 2
pallor 2
tachypnea 2
rhinorrhea 2
dysarthria 2
despair 2
dystonia 2
emaciation 2
right upper quadrant pain 2
blurred vision 2
hyperoxia 2
jaundice of the skin 2
leg pain 2
frequent urination 2
acute abdomen 2
cerebellar ataxia 2
night sweats 2
hypercapnia 2
orthopnea 1
dark urine 1
pedal edema 1
rigors 1
eye pain 1
ACHE 1
rib pain 1
sinus congestion 1
numbness 1
Welt 1
bloating 1
meningism 1
stomach pain 1
non-productive cough 1
Kayser-Fleischer ring 1
muscle cramps 1
chronic constipation 1
tense 1
clubbing 1
liver pain 1
ECG signs of myocardial ischemia 1
gumma 1
productive cough 1
DNA marker 1
drooling 1
tonic-clonic seizure 1
intestinal bleeding 1
hypersomnia 1
dysuria 1
Flu-like symptoms 1
knee pain 1
insomnia 1
Fluctuation 1
memory loss 1
flank pain 1
Wind 1
vertigo 1
periorbital edema 1
heartburn 1
Limb weakness 1
Respiratory symptoms 1
wheezing 1
hemoptysis 1
adenitis 1
cachexia 1
arm weakness 1
thinning 1
hypocapnia 1
chest tightness 1
photophobia 1
breast hyperplasia 1
exertional dyspnea 1
hip pain 1
ENT 1
hot flashes 1
hypertonia 1
muscle rigidity 1
inanition 1
cancer pain 1
hyperesthesia 1
Drug
ROS 100
ascorbate 45
vitamin E 43
IL-2 42
Ethanol 23
ROC 21
Monit 20
TAC 19
CTX 18
Alanine 17
Albumin 17
IFN-gamma 16
Dial 14
Nephron 13
Vitamin E 13
CSF 13
MAP 13
Glutathione 11
Nephron 11
ALA 10
lysine 10
Heme 10
CCL 10
Bifidobacterium 10
Dermatol 10
CTX 9
Cardiovasc 9
caffeine 9
CTX 9
Portal 8
Fructose 8
NAG 7
Serum albumin 7
ampicillin 7
Tacrolimus 6
lactose 6
Leaf 6
Aloe 6
NH3 6
Asn 5
Vitamin B 5
ZnO 5
Rosiglitazone 5
Acacia 5
Simvastatin 5
Rutin 5
Glycyrrhiza 5
pyridoxal phosphate 4
Ginseng 4
ENT 4
NADH 4
Biopolymers 4
Liraglutide 4
Captopril 4
Ringer's solution 4
Sorafenib 4
TiO2 4
TTC 4
Emodin 3
Caspofungin 3
EPA 3
RFP 3
Senna 3
Emodin 3
Prednisone 3
G-CSF 3
Isotretinoin 3
Rosuvastatin 3
PMEA 3
Fluorescein 3
Senna 3
MOF 3
MRC 3
TMS 3
Isoniazid 3
Ranitidine 3
Gel 3
EE2 3
niacin 3
DNase I 3
OTC 3
DPA 2
Furan 2
DM1 2
Vitamin A 2
Methylprednisolone 2
GEO 2
Honey 2
HCH 2
Ofloxacin 2
Ceftazidime 2
Itraconazole 2
Infliximab 2
Propofol 2
TAK 2
NAH 2
Activin 2
OTC 2
DMAP 2
Retinoic acid 2
Lovastatin 2
Gelatin 2
Entecavir 2
Entecavir 2
metformin hydrochloride 2
PCP 2
Angiotensin II 2
PTC 2
uPA 2
Histamine 2
NBT 2
Swertia 2
Trabectedin 2
Moxifloxacin 2
ETA 2
Neoral 2
Olive oil 2
Fluconazole 2
Infliximab 2
Arsenic trioxide 2
Adriamycin 2
ADR 2
Iloprost 2
Artesunate 2
Nitric Oxide 2
ETS 2
Posaconazole 2
PCB 2
Oxacillin 2
Capsicum 2
Lead acetate 2
NLF 2
LCM 1
Indomethacin 1
Etoposide 1
citric acid 1
LCM 1
Ketotifen 1
Darapladib 1
9-THC 1
L-Ser 1
CDX 1
CIA 1
Fulvestrant 1
Medetomidine 1
Retinoic Acid 1
Azithromycin 1
Plantago seed 1
Kayexalate 1
Galactose 1
Tiopronin 1
MDS 1
Lifibrol 1
Ipilimumab 1
CTC 1
Rokitamycin 1
Darunavir 1
Asthma 1
ACT 1
PFA 1
more...
Enzyme
AST 6066
aspartate aminotransferase 6039
alanine aminotransferase 4535
superoxide dismutase 728
catalase 528
gamma-glutamyl transpeptidase 527
alkaline phosphatase 378
lactate dehydrogenase 190
glutathione peroxidase 176
creatine kinase 171
glutathione S-transferase 135
caspase-3 119
mitogen-activated protein kinase 103
peroxidase 102
ERK 66
acetylcholinesterase 48
AMP-activated protein kinase 48
lipase 45
glutathione reductase 43
cholinesterase 42
AMPK 37
AMPK 37
NQO1 31
ATPase 28
focal adhesion kinase 28
glucose-6-phosphate dehydrogenase 22
caspase-9 22
glutamate dehydrogenase 21
glutamate dehydrogenase 21
glutamate dehydrogenase 21
lysozyme 20
protein kinase 19
CYP3A4 19
malate dehydrogenase 18
PARP 17
MIP 16
luciferase 16
alcohol dehydrogenase 15
MDH 15
thromboplastin 15
MDH 15
reverse transcriptase 15
collagenase 14
caspase-1 14
CPT 14
GMT 14
acid phosphatase 13
NOS 13
ACE 12
xanthine oxidase 12
ceruloplasmin 10
acetyl-CoA carboxylase 10
MMP 10
PST 10
LPL 10
phosphoenolpyruvate carboxykinase 10
glucose-6-phosphatase 10
aryl sulfotransferase IV 9
MAP 9
CYP7A1 9
aldehyde dehydrogenase 9
GSK 9
gamma-glutamylcysteine synthetase 9
arginase 9
CPT 8
NADPH oxidase 8
hexokinase 8
heme oxygenase 8
CPT 8
caspase-8 8
renin 8
transpeptidase 7
ECH 7
estrogen sulfotransferase 7
SOAT 7
aldolase 7
glutamine synthetase 7
NADPH oxidase 7
NO synthase 7
thymidine kinase 7
succinate dehydrogenase 6
MTD 6
thrombin 6
5'-nucleotidase 6
RNA polymerase 6
phosphoenolpyruvate carboxykinase 6
phosphoenolpyruvate carboxykinase 6
transcriptase 6
ornithine transcarbamylase 6
IKK 5
beta-galactosidase 5
elastase 5
trypsin 5
proteasome 5
ADH 5
alpha-amylase 5
delta-aminolevulinic acid dehydratase 5
beta-lactamase 5
DNA polymerase 5
TSA 4
GLO 4
PCE 4
cytochrome oxidase 4
matrix metalloproteinase 9 4
urokinase-type plasminogen activator 4
CD10 4
phospholipase A2 4
fructose 1,6-bisphosphatase 4
nitrate reductase 3
acyl-CoA oxidase 3
nitrate reductase 3
SADH 3
nitrate reductase 3
nitrate reductase 3
TACE 3
hexosaminidase 3
aldehyde dehydrogenase 3
adenosine deaminase 3
purine nucleoside phosphorylase 3
soluble epoxide hydrolase 3
P-glycoprotein 3
aldehyde dehydrogenase 3
adenosine deaminase 3
ALDH 3
demethylase 3
BAL 3
protein kinase C 3
nitrate reductase 3
diacylglycerol acyltransferase 3
PAL 3
nitrate reductase 3
phosphorylase 3
UDP-glucuronosyltransferase 3
lipoprotein lipase 3
aldehyde dehydrogenase 3
aldehyde dehydrogenase 3
matrix metalloproteinase 2 3
glucokinase 3
MEK 3
chymotrypsin 3
paraoxonase 3
type III procollagen 3
ACS 3
prostate-specific antigen 3
granzyme B 3
cathepsin B 3
tyrosine aminotransferase 3
paraoxonase 3
hormone-sensitive lipase 3
phosphodiesterase 2
peroxiredoxin 2
dimethylarginine dimethylaminohydrolase 2
carbamoylphosphate synthetase 2
TOR 2
arylsulfate sulfotransferase 2
acetylornithine aminotransferase 2
BAT 2
nucleotidase 2
complex I 2
SST 2
more...
Compound
ALP 845
creatinine 687
GSH 631
GSH 631
glucose 601
urea 526
TNF 476
MDA 439
Clin 425
Dec 418
water 357
DNA 281
CAT 278
CAT 271
CAT 271
ethanol 236
oxygen 222
alanine 214
sodium 175
CCl4 166
calcium 148
nitrogen 131
iron 115
APAP 107
nitric oxide 107
potassium 106
sulfate 82
phosphate 68
ammonia 66
zinc 64
ATP 62
methionine 60
copper 59
phosphorus 56
acetate 53
arginine 52
methanol 51
selenium 46
cadmium 46
galactose 46
His 41
cysteine 40
MTT 39
GPT 38
N-acetylcysteine 38
DPPH 37
ethyl acetate 35
GSSG 34
glutamate 32
Asp 31
MCH 31
GTP 30
hyaluronic acid 30
nitrate 29
leucine 28
hydrogen 28
Bilirubin 28
salt 26
gallic acid 25
alloxan 25
tyrosine 25
TSH 24
Indoxyl sulfate 24
STZ 24
NH2 23
H2O2 23
PEG 23
TOF 22
silver 22
tryptophan 21
tryptophan 21
aspartic acid 21
Silymarin 21
Curcumin 20
Malondialdehyde 20
tryptophan 20
Phe 20
CO2 20
hexane 20
8-OHdG 20
tryptophan 20
Insulin 19
TEM 19
DEN 19
CTX 18
INH 18
MIC 18
Cholesterol 18
DMSO 17
manganese 17
Alanine 17
Pac 17
FFA 16
Quercetin 16
PEG 16
Arsenic 16
ADR 16
DDP 16
ASA 16
Adriamycin 16
chloroform 15
glutamine 15
2-oxoglutarate 15
phenol 15
alcohol dehydrogenase 15
nicotinamide 15
serine 14
lysine 14
kaempferol 14
Dial 14
TAA 14
Vitamin E 13
Lactate 13
acetic acid 13
ANA 13
chromium 13
PGE2 13
CoA 13
mercury 13
aflatoxin B1 13
SDS 13
ANA 13
Gly 13
ADP 12
aluminum 12
pyrene 12
vitamin D 12
ornithine 12
ornithine 12
ADP 12
Hematoxylin 12
ornithine 12
ornithine 12
NAD 12
Oil Red O 12
Oil Red O 12
DBA 12
ADP 12
ornithine 12
aldehyde 12
Methotrexate 11
iodine 11
NAD 11
homocysteine 11
threonine 11
palmitic acid 11
palmitic acid 11
dUTP 11
Ile 11
L-carnitine 11
cAMP 10
DBP 10
Cyclosporine 10
MAP 10
Heme 10
betaine 10
xylose 10
acetaldehyde 10
FK506 9
glycerol 9
more...