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Query: EC:2.3.1.109 (AST)
 6,066 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Twenty biochemical parameters have been studied in 94 athlets of Marcialonga in basic conditions and after 30 min from the end of the competition. Urea, uric acid, creatinin, total proteins, albumin, sodium, calcium, phosphorus and several enzymes (AST, ALT, LAD, CK and ALP) have shown statistically significant increasings. It is, above all, clear the increasing of CK. On the contrary triglycerides have undergone a significant decreasing. The AA. try to explain the results obtained, considering some pathogenetic theories.
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PMID:[A study of biochemical parameters in 94 athlets of Marcialonga (author's transl)]. 75 25

1. The prairie dog has been used extensively for the study of gallstone genesis and gallstone dissolution therapies, and has recently been implicated in an effort to prevent total parenteral nutrition-associated cholelithiasis with intravenous chenodeoxycholate. 2. Towards this effort, it is important that a range of normal blood chemistry values be reported for the prairie dog. This paper reports the mean values for a complete blood cell count, electrolytes, blood urea nitrogen, creatinine, calcium, phosphorus, liver enzymes, total bilirubin, protein, albumin, cholesterol, triglycerides and lipids for 45 adult prairie dogs. 3. The prairie dog has normochromic, microcytic blood with an increased number of red blood cells. The prairie dog also has a high concentration of small platelets. 4. The prairie dog has a higher CO2 concentration with a slightly increased potassium concentration than is found in man. The anion gap is 12 with a calculated serum osmolality of 316. The BUN concentration is elevated with a 3-fold increase in the AST concentration. 5. The prairie dog has lower serum values for cholesterol, VLDL and LDL cholesterol than man. In the prairie dog, HDL cholesterol consists of 67% of the total cholesterol concentration and the LDL and HDL ratio is 0.3.
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PMID:Hematologic and blood chemistry data for the prairie dog (Cynomys ludovicianus). 135 55

A moderate malignant hyperthermia developed in a Labrador Retriever anaesthetized with isoflurane for a femoral shaft fracture repair. Signs of malignant hyperthermia included progressive increases in PETCO2 and rectal temperature up to 39.8 degrees C, tachycardia, cyanosis, and elevated serum levels of potassium, inorganic phosphorus, AST, CK and alkaline phosphatase. Treatment initiated in the early recovery period consisted of hyperventilation with 100% oxygen, stomach lavage with iced water, body surface cooling, and intravenous administration of cold isotonic saline solution. Cooling was continued until the rectal temperature had dropped to 37.3 degrees C. After treatment the dog recovered uneventfully. Clinical signs, pathophysiology, therapy, prevention of malignant hyperthermia and its association with other disorders are discussed.
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PMID:[Malignant hyperthermia as a complication of anesthesia in the dog]. 144 May 99

Six HK (high erythrocyte potassium) and 7 LK (low erythrocyte potassium) dairy cows were subjected to a 4-h intravenous infusion of 4.7% Na2EDTA solution to induce and maintain hypocalcaemia. Blood samples taken immediately before infusion, hourly for 7 h, and at 24 h after commencement of infusion were subjected to determination of concentration (or count) of 16 analytes. The mean changes in concentrations (or counts) of the various blood analytes were calculated for the periods 0-4, 4-7, 7-24, and 0-24 h after commencement of the infusion for all cows combined, and then separately for the HK and LK groups of cows. Plasma Ca(PCa), plasma inorganic phosphorus (PiP) and plasma potassium (PK) showed significant decreases during the 4-h infusion period and were still below pretreatment levels 24 h later. AST, CPK, PCVs and white cell-counts (WCCs) showed significant early increases which were still significantly elevated 24 h later. Plasma magnesium (PMg) and erythrocyte Na(ENa) and K(EK) all showed delayed changes which still persisted 24 h later. Significant between-group differences were present for PCVs which increased significantly more in the LK than the HK group during the infusion period, for PCa which showed a greater increase in the HK cows than the LK cows during the 4-7 h early clinical recovery period, and for plasma bilirubin (PBil) which showed a greater increase from 0 to 24 h in the HK group than in the LK group. Urine samples, collected before infusion, 4-7 h and 24 h after commencement of the infusion, were subjected to analysis for glucose, protein, pH, 'blood' and ketones. Most cows showed increases in urinary glucose, protein and 'blood'.
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PMID:The effects of hypocalcaemia due to a 4-hour infusion of Na2EDTA solution on various blood and urine analytes in dairy cows and a comparison of these effects between cows with high and low erythrocyte potassium concentrations. 149 40

Egyptian scorpion venom was collected by electrical stimulation of the telson. Rats were injected with the lyophilized venom in 3 different doses (100, 200 and 400 micrograms/kg). Blood samples were drawn by heart puncture before and 4 h after venom administration. Serum was separated and collected for determination of glucose, blood urea nitrogen (BUN), creatinine, uric acid (UA), total proteins, cholesterol, sodium, potassium, calcium, inorganic phosphorus, alkaline phosphatase, aspartate aminotransferase (AST, GOT), alanine aminotransferase (ALT, GPT), lactate dehydrogenase and creatine phosphokinase (CPK). Serum glucose, creatinine, GOT, GPT and LDH were increased significantly in all treatments. At the same time serum BUN and CPK were elevated significantly with a dose-response relationship. On the other hand, serum total proteins, uric acid, cholesterol, calcium and potassium were significantly decreased 4 h after administration of the 3 doses. These changes in clinical chemistry parameters are most probably related to the toxic effect of the venom on the target organs.
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PMID:Effect of scorpion Leiurus quinquestriatus (H&E) venom on the clinical chemistry parameters of the rat. 160 45

Blood samples were collected from v. jugularis in five-day intervals from parturition to postpartum day 45 in the rearing conditions of a dairy cow production herd, consisting of 10 groups with 10 pluriparous cows each (crossbreds of Bohemian Pied cattle with Holstein-Friesian cattle). In blood serum the following activities were determined photometrically: aspartate aminotransferase--AST (0.36-0.47 mukat.l-1), gamma-glutamyl transferase--GMT (0.50-0.83 mukat.l-1) and lactate dehydrogenase--LD (7.22-9.10 mukat.l-1); their average values were at an almost constant level. Only did AST and GMT values decrease slightly from day 25 after parturition. The glucose average content on the day of parturition (4.07 mmol.l-1) steeply decreased to postpartum day 5 (2.79 mmol.l-1), and later on, it increased irregularly. The average values of total protein (66.7-73.2 g per 1) slightly increased from postpartum day 20. The values of urea (2.33-2.37 mmol.l-1) and bilirubin (3.49-5.15 mmol.l-1) did not show any larger changes in dependence on the time elapsing from parturition. The average content of creatinine (124-162 mmol.l-1) increased irregularly from postpartum day 15 and then it decreased. Cholesterol concentrations were gradually increasing from 2.58 mmol.l-1 on the day of parturition to 4.99 mmol.l-1 on day 45 after parturition. The average contents of calcium (2.20-2.66 mmol.l-1) and phosphorus (1.75-2.27 mmol.l-1) were irregularly increasing until day 20 after parturition. Also the average content of magnesium (0.86-1.15 mmol.l-1) rose from day 25 after parturition.
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PMID:[Biochemical changes in the peripheral blood in cows 45 days after parturition]. 168 73

Blood and milk samples were taken at first insemination in 352 dairy cows from 18 herds for charting the relation between clinico-chemical parameters and fertility rate. Neither total protein, albumin, globulin, AST, bilirubin, bile acids, calcium, magnesium and phosphorus in blood nor urea in milk was significantly related to the rate of pregnancy. On the other hand, there was a significant difference for plasma glucose between cows that became pregnant and those that did not. Cows with low plasma glucose concentrations at first insemination also had low values four and seven weeks after calving, indicating that it is primarily cows with chronically low blood glucose which are likely to have reduced fertility. At first insemination there was no increase in the concentration of acetone in milk of cows with reduced fertility. However, they had had increased milk acetone concentrations three to five weeks after calving. It therefore seems possible to evaluate the risk of reduced fertility by measuring either blood glucose or milk acetone some weeks after calving. Owing to the difficulties associated with the sampling and laboratory techniques for glucose, analyses of milk acetone are more suitable under field conditions.
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PMID:The relationships between the fertility of dairy cows and clinical and biochemical measurements, with special reference to plasma glucose and milk acetone. 177 82

62 specimens of cystic fluid drawn back by ultrasound guided needle-aspiration in 37 males and 25 females were evaluated biochemical analysis including magnesium, calcium, phosphorus, chloride, uric acid, total protein, sugar, urea, creatinine, sodium, potassium, total cholesterol, AST, ALT, ALP, ACP, PAP, alpha-amilasys. In our study Cl, Na and sugar showed similar concentrations in the two fluids. Uric acid, and urea were more concentrated in the cystic fluid while Mg, Ca and total protein were more pronounced in the blood. The results obtained seem to indicate that simple renal cyst could originate from glomerular proximal tubulus part of the nephron as consequence of an obstructive cause.
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PMID:[Simple renal cysts, biochemical analysis of the cystic fluid, and comparison with blood parameters]. 183 Apr 3

Through the present delta value check used in quality control programs is a powerful tool for detecting random errors in clinical chemistry analysis, it has some problems, such as missed true errors and delays in reporting time, because it also has the potential of showing erroneous positive results. Recently, new calculation methods for delta check with delta difference, delta percent change, rate difference, and rate percent change have been suggested by Lacher and Connelly (Clin Chem 34:1966-1970, 1988). Based on this new delta check method, we made the new criteria of which calculation method is applied to the clinical chemistry tests, i.e., the differential application of rate and delta check, and selectively applied the new method to 17 chemistry tests in order to solve the above problems. The applied criteria were the time dependence of the test item and the coefficient of variation of the absolute delta difference. Calcium, inorganic phosphorus, total protein, albumin, sodium, potassium, and chloride were classified as delta difference calculation method group; glucose and cholesterol as delta percent change group; creatinine, total and direct bilirubin as rate difference group; and urea nitrogen, uric acid, ALP, ALT, and AST as rate percent change group. With the previous criteria by Whitehurst et al. (Clin Chem 221:87-92) for 5045 specimens, the check-out rate was 47.8% (2,411 out of 5,045), and the positive predictive value was 0.41% (10 out of 2,411). For the new criteria, the check-out rate was 12.7% (621 out of 5,045), and the positive predictive value was 1.8% (nine out of 621).(ABSTRACT TRUNCATED AT 250 WORDS)
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PMID:Differential application of rate and delta check on selected clinical chemistry tests. 210 Jan 25

The importance of calcium and phosphorus metabolism for the development of hypertrophic cardiomyopathies is still obscure. Therefore 52 patients with hypertrophic cardiomyopathy were subjected to detailed cardiological and laboratory examinations. Twenty-five age matched healthy subjects served as controls. The following indicators were assessed: calcium and its ionized fraction, phosphorus, chlorides and magnesium in serum and 24 h urine, as well as AST, ALT, ALP, ACP, urea, creatinine, protein electrophoresis (to check calcium values with regard to serum albumins), endogenous creatinine clearance, Palmer's chloride phosphate index and Nordin's index. In addition to tubular phosphate reabsorption, the renal phosphate threshold was assessed and finally the parathormone blood level by the RIA method. In patients with hypertrophic cardiomyopathy a significant increase of the parathormone level was found--in a total of seven patients with advanced myocardial hypertrophy (more than 30 mm). There were no significant differences in the remaining parameters. It may thus be admitted that in some instances the increased parathormone level may cause an increase of the already existing myocardial hypertrophy. However, in the broad spectrum of patients with hypertrophic cardiomyopathy it is not suited for explaining morphological findings.
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PMID:[Are there abnormalities of parathormone, calcium and phosphorus metabolism in hypertrophic cardiomyopathy?]. 237 75


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