Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:2.3.1.108 (
TAT
)
2,389
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
We examined the production and secretion of fusion constructs containing alpha-N-acetylglucosaminidase, the enzyme deficient in
Sanfilippo
B, and either wildtype
TAT
or modified
TAT
in cultured Spodoptera frugiperda cells. All constructs exhibited successful expression of active enzyme, suggesting the future possibility of utilizing
TAT
/alpha-N-acetylglucosaminidase chimerae in enzyme replacement therapy.
...
PMID:Expression of active alpha-N-acetylglucosaminidase/TAT Chimerae in cultured Spodoptera frugiperda cells. 1671 10
